CN113811604A - Car-nk细胞的产生方法及其用途 - Google Patents

Car-nk细胞的产生方法及其用途 Download PDF

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CN113811604A
CN113811604A CN202080032042.7A CN202080032042A CN113811604A CN 113811604 A CN113811604 A CN 113811604A CN 202080032042 A CN202080032042 A CN 202080032042A CN 113811604 A CN113811604 A CN 113811604A
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cells
car
cell
antigen
patients
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K·雷兹瓦尼
E·施帕尔
刘恩莉
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University of Texas System
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CN202080032042.7A 2019-03-29 2020-03-25 Car-nk细胞的产生方法及其用途 Pending CN113811604A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962826856P 2019-03-29 2019-03-29
US62/826,856 2019-03-29
PCT/US2020/024671 WO2020205359A1 (en) 2019-03-29 2020-03-25 Methods for production of car-nk cells and use thereof

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CN113811604A true CN113811604A (zh) 2021-12-17

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US (1) US20220325245A1 (enExample)
EP (1) EP3947647A4 (enExample)
JP (1) JP2022519935A (enExample)
KR (1) KR20220004992A (enExample)
CN (1) CN113811604A (enExample)
AR (1) AR118510A1 (enExample)
AU (1) AU2020254420A1 (enExample)
BR (1) BR112021019411A2 (enExample)
CA (1) CA3135407A1 (enExample)
CO (1) CO2021012719A2 (enExample)
MX (1) MX2021011816A (enExample)
TW (1) TW202104252A (enExample)
WO (1) WO2020205359A1 (enExample)

Cited By (5)

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Publication number Priority date Publication date Assignee Title
CN115896016A (zh) * 2022-09-07 2023-04-04 普华赛尔生物医疗科技有限公司 培养组合物及其在培养免疫细胞中的应用
CN116168765A (zh) * 2023-04-25 2023-05-26 山东大学 基于改进strobemer的基因序列生成方法及系统
CN116262793A (zh) * 2021-12-13 2023-06-16 上海恒润达生生物科技股份有限公司 膜整合型融合蛋白、含有其的细胞及用途
CN116769722A (zh) * 2023-07-04 2023-09-19 杭州荣谷生物科技有限公司 功能增强型car-nk细胞、其制备方法及其在免疫疗法中的应用
WO2025067151A1 (en) * 2023-09-25 2025-04-03 Nanjing Legend Biotech Co., Ltd. Modified immune cells and calcineurin inhibitors and uses thereof

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IL276365B2 (en) 2018-02-01 2023-10-01 Nkmax Co Ltd A method for the production of natural killer cells and a preparation for cancer treatment
US12473336B2 (en) 2018-02-21 2025-11-18 Board Of Regents, The University Of Texas System Methods for activation and expansion of natural killer cells and uses thereof
KR20210005240A (ko) * 2018-05-03 2021-01-13 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 면역 관문 차단과 함께 키메라 항원 수용체를 발현하도록 가공된 천연 킬러 세포
GB202005216D0 (en) * 2020-04-08 2020-05-20 Autolus Ltd Cell
US20240325443A1 (en) * 2021-07-23 2024-10-03 Board Of Regents, The University Of Texas System Cd3-expressing natural killer cells with enhanced function for adoptive immunotherapy
CA3244259A1 (en) * 2022-02-23 2023-08-31 Aloe Therapeutics Inc Compositions and methods for modulating the immune system
WO2024058589A1 (ko) * 2022-09-16 2024-03-21 한국과학기술연구원 유전자 가위 넉-인을 이용하여 제조한 키메릭 항원 수용체 세포 및 이의 용도
IL320156A (en) * 2022-10-10 2025-06-01 Kite Pharma Inc New large scale car-t immune cell manufacturing method utilizing lentiviral vector transfection
AU2024279278A1 (en) 2023-05-31 2025-12-18 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
WO2025006799A1 (en) * 2023-06-27 2025-01-02 Capstan Therapeutics, Inc. Extracorporeal and ex vivo engineering of select cell populations from peripheral blood
WO2025169136A1 (en) * 2024-02-09 2025-08-14 Takeda Pharmaceutical Company Limited Dosing regimen for cd19 car nk cells in treating cancer
US20250333700A1 (en) * 2024-02-28 2025-10-30 Gene Solutions Joint Stock Company Modified k562 feeder cell line expressing factors that enhance the activation and proliferation of natural killer cells and a method for its production

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WO2018195339A1 (en) * 2017-04-19 2018-10-25 Board Of Regents, The University Of Texas System Immune cells expressing engineered antigen receptors

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HK1245080A1 (zh) * 2014-10-27 2018-08-24 University Of Central Florida Research Foundation, Inc. 自然杀伤细胞的方法和组合物
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EP3755347B1 (en) * 2018-02-21 2025-06-25 Board of Regents, The University of Texas System Universal antigen presenting cells and uses thereof
KR20210005240A (ko) * 2018-05-03 2021-01-13 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 면역 관문 차단과 함께 키메라 항원 수용체를 발현하도록 가공된 천연 킬러 세포
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WO2018195339A1 (en) * 2017-04-19 2018-10-25 Board Of Regents, The University Of Texas System Immune cells expressing engineered antigen receptors

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116262793A (zh) * 2021-12-13 2023-06-16 上海恒润达生生物科技股份有限公司 膜整合型融合蛋白、含有其的细胞及用途
CN115896016A (zh) * 2022-09-07 2023-04-04 普华赛尔生物医疗科技有限公司 培养组合物及其在培养免疫细胞中的应用
CN115896016B (zh) * 2022-09-07 2023-09-12 普华赛尔生物医疗科技有限公司 培养组合物及其在培养免疫细胞中的应用
CN116168765A (zh) * 2023-04-25 2023-05-26 山东大学 基于改进strobemer的基因序列生成方法及系统
CN116168765B (zh) * 2023-04-25 2023-08-18 山东大学 基于改进strobemer的基因序列生成方法及系统
CN116769722A (zh) * 2023-07-04 2023-09-19 杭州荣谷生物科技有限公司 功能增强型car-nk细胞、其制备方法及其在免疫疗法中的应用
WO2025067151A1 (en) * 2023-09-25 2025-04-03 Nanjing Legend Biotech Co., Ltd. Modified immune cells and calcineurin inhibitors and uses thereof

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TW202104252A (zh) 2021-02-01
JP2022519935A (ja) 2022-03-25
US20220325245A1 (en) 2022-10-13
KR20220004992A (ko) 2022-01-12
BR112021019411A2 (pt) 2021-11-30
MX2021011816A (es) 2021-10-22
AR118510A1 (es) 2021-10-20
EP3947647A4 (en) 2023-01-04
CA3135407A1 (en) 2020-10-08
EP3947647A1 (en) 2022-02-09
WO2020205359A1 (en) 2020-10-08
AU2020254420A1 (en) 2021-11-11
CO2021012719A2 (es) 2021-10-20

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