JP2022519690A - 単離された細胞培養成分、及びそれを液状の細胞培養培地から単離する方法 - Google Patents

単離された細胞培養成分、及びそれを液状の細胞培養培地から単離する方法 Download PDF

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JP2022519690A
JP2022519690A JP2021545993A JP2021545993A JP2022519690A JP 2022519690 A JP2022519690 A JP 2022519690A JP 2021545993 A JP2021545993 A JP 2021545993A JP 2021545993 A JP2021545993 A JP 2021545993A JP 2022519690 A JP2022519690 A JP 2022519690A
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cell culture
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リー ビターフィールド，デボラ
クイン ドハーティ，ミッシェル
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リンディー バイオサイエンシーズ，インク．
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/06—Hydrolysis; Cell lysis; Extraction of intracellular or cell wall material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/145—Extraction; Separation; Purification by extraction or solubilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/08—Homogenizing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12—Purification

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  • Engineering & Computer Science (AREA)
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  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
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  • Genetics & Genomics (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
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  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2021545993A 2019-02-05 2020-02-05 単離された細胞培養成分、及びそれを液状の細胞培養培地から単離する方法 Pending JP2022519690A (ja)

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JP2024199964A JP2025026925A (ja) 2019-02-05 2024-11-15 単離された細胞培養成分、及びそれを液状の細胞培養培地から単離する方法

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US201962801225P 2019-02-05 2019-02-05
US62/801,225 2019-02-05
PCT/US2020/016743 WO2020163446A1 (en) 2019-02-05 2020-02-05 Isolated cell culture components and methods for isolating the same from liquid cell culture medium

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JP2022519690A true JP2022519690A (ja) 2022-03-24
JP2022519690A5 JP2022519690A5 (https=) 2023-02-13

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JP2024199964A Pending JP2025026925A (ja) 2019-02-05 2024-11-15 単離された細胞培養成分、及びそれを液状の細胞培養培地から単離する方法

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US (2) US20220119760A1 (https=)
EP (1) EP3921082A4 (https=)
JP (2) JP2022519690A (https=)
KR (1) KR102941878B1 (https=)
CN (1) CN113661006A (https=)
AU (2) AU2020219125B2 (https=)
CA (1) CA3128204C (https=)
SG (1) SG11202107901QA (https=)
WO (1) WO2020163446A1 (https=)

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AU2018306303A1 (en) 2017-07-25 2020-02-20 Elektrofi, Inc. Formation of particles including agents
WO2019226969A1 (en) 2018-05-24 2019-11-28 Elektrofi, Inc. Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof
EP3917500A2 (en) 2019-01-31 2021-12-08 Elektrofi, Inc. Particle formation and morphology
CN113661006A (zh) 2019-02-05 2021-11-16 林迪生物科学公司 分离的细胞培养物组分以及用于从液体细胞培养基中分离其的方法
EP4027978A1 (en) 2019-09-13 2022-07-20 Elektrofi, Inc. Compositions and methods for the delivery of therapeutic biologics for treatment of disease
WO2021212019A1 (en) 2020-04-17 2021-10-21 Elektrofi, Inc. Methods of forming particles by continuous droplet formation and dehydration
CN112675935B (zh) * 2021-01-22 2022-03-25 中国科学院上海微系统与信息技术研究所 用于单细胞冷冻的液滴阵列芯片及液滴生成方法和应用
WO2024177927A1 (en) * 2023-02-20 2024-08-29 Lindy Biosciences, Inc. Hyaluronidase particles, compositions comprising the same and methods of making and using the same

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CA3128204A1 (en) 2020-08-13
US20220119760A1 (en) 2022-04-21
WO2020163446A1 (en) 2020-08-13
AU2020219125B2 (en) 2025-10-02
KR20210125032A (ko) 2021-10-15
KR102941878B1 (ko) 2026-03-23
EP3921082A4 (en) 2022-11-02
AU2025237973A1 (en) 2025-10-16
AU2020219125A1 (en) 2021-08-12
JP2025026925A (ja) 2025-02-26
EP3921082A1 (en) 2021-12-15
CA3128204C (en) 2025-06-10
US20230093954A1 (en) 2023-03-30
US11795429B2 (en) 2023-10-24
SG11202107901QA (en) 2021-08-30
CN113661006A (zh) 2021-11-16

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