|
US5436146A
(en)
|
1989-09-07 |
1995-07-25 |
The Trustees Of Princeton University |
Helper-free stocks of recombinant adeno-associated virus vectors
|
|
US5173414A
(en)
|
1990-10-30 |
1992-12-22 |
Applied Immune Sciences, Inc. |
Production of recombinant adeno-associated virus vectors
|
|
US5387484A
(en)
|
1992-07-07 |
1995-02-07 |
International Business Machines Corporation |
Two-sided mask for patterning of materials with electromagnetic radiation
|
|
US5658785A
(en)
|
1994-06-06 |
1997-08-19 |
Children's Hospital, Inc. |
Adeno-associated virus materials and methods
|
|
US5872005A
(en)
|
1994-11-03 |
1999-02-16 |
Cell Genesys Inc. |
Packaging cell lines for adeno-associated viral vectors
|
|
US6924128B2
(en)
|
1994-12-06 |
2005-08-02 |
Targeted Genetics Corporation |
Packaging cell lines for generation of high titers of recombinant AAV vectors
|
|
IL116816A
(en)
|
1995-01-20 |
2003-05-29 |
Rhone Poulenc Rorer Sa |
Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
|
|
US5688676A
(en)
|
1995-06-07 |
1997-11-18 |
Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
|
US5741683A
(en)
|
1995-06-07 |
1998-04-21 |
The Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
|
US6027931A
(en)
|
1995-08-03 |
2000-02-22 |
Avigen, Inc. |
High-efficiency AA V helper functions
|
|
US6004797A
(en)
|
1995-11-09 |
1999-12-21 |
Avigen, Inc. |
Adenovirus helper-free recombinant AAV Virion production
|
|
CA2270285A1
(en)
|
1996-12-18 |
1998-06-25 |
Targeted Genetics Corporation |
Aav split-packaging genes and cell lines comprising such genes for use in the production of recombinant aav vectors
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
US6566118B1
(en)
|
1997-09-05 |
2003-05-20 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
|
US6995006B2
(en)
|
1997-09-05 |
2006-02-07 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
|
WO1999014354A1
(en)
|
1997-09-19 |
1999-03-25 |
The Trustees Of The University Of The Pennsylvania |
Methods and vector constructs useful for production of recombinant aav
|
|
IT1297074B1
(it)
|
1997-11-21 |
1999-08-03 |
Angeletti P Ist Richerche Bio |
Forme ormone-dipendenti delle proteine rep del virus adeno-associato (aav-2), sequenze di dna codificanti per esse, vettori che le
|
|
US6759050B1
(en)
|
1998-12-03 |
2004-07-06 |
Avigen, Inc. |
Excipients for use in adeno-associated virus pharmaceutical formulations, and pharmaceutical formulations made therewith
|
|
DE19905501B4
(de)
|
1999-02-10 |
2005-05-19 |
MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie |
Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels
|
|
JP2002191363A
(ja)
*
|
1999-07-29 |
2002-07-09 |
Herikkusu Kenkyusho:Kk |
全長ｃＤＮＡ合成用プライマー、およびその用途
|
|
US20040235173A1
(en)
|
2000-07-03 |
2004-11-25 |
Gala Design, Inc. |
Production of host cells containing multiple integrating vectors by serial transduction
|
|
US6723551B2
(en)
|
2001-11-09 |
2004-04-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Production of adeno-associated virus in insect cells
|
|
EP1572893B1
(en)
|
2001-11-09 |
2009-01-07 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY of the DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Production of adeno-associated virus in insect cells
|
|
DK2359869T3
(en)
|
2001-12-17 |
2019-04-15 |
Univ Pennsylvania |
Sequences of adeno-associated virus (AAV) serotype 8, vectors containing these, and uses thereof
|
|
CA2369985A1
(en)
|
2002-01-18 |
2003-07-18 |
Duke University |
Generation of recombinant adeno-associated viral vectors by a complete adenovirus-mediated approach
|
|
US7510872B2
(en)
|
2003-02-26 |
2009-03-31 |
Nationwide Children's Hospital |
Recombinant adeno-associated virus production
|
|
JP4559429B2
(ja)
|
2003-05-21 |
2010-10-06 |
ジェンザイム・コーポレーション |
空キャプシドを実質的に含まない組換えａａｖビリオン調製物を生成するための方法
|
|
EP1668143B1
(en)
|
2003-09-30 |
2013-03-20 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor
|
|
US7195394B2
(en)
|
2004-07-19 |
2007-03-27 |
Vijay Singh |
Method for resonant wave mixing in closed containers
|
|
US8980247B2
(en)
|
2004-10-21 |
2015-03-17 |
The Penn State Research Foundation |
Parvovirus methods and compositions for killing neoplastic cells
|
|
PT3272872T
(pt)
|
2005-10-20 |
2020-06-26 |
Uniqure Ip Bv |
Vetores aav melhorados produzidos em células de insetos
|
|
WO2007148971A2
(en)
|
2006-06-21 |
2007-12-27 |
Amsterdam Molecular Therapeutics B.V. |
Vectors with modified initiation codon for the translation of aav-rep78 useful for production of aav in insect cells
|
|
GB0706638D0
(en)
|
2007-04-04 |
2007-05-16 |
Mbda Uk Ltd |
A high-dielectric material
|
|
EP2242840B1
(en)
|
2008-01-29 |
2019-07-24 |
Applied Genetic Technologies Corporation |
Recombinant adeno-associated virus production using bhk cells in suspension
|
|
US8580755B2
(en)
|
2008-02-19 |
2013-11-12 |
University Of Rochester |
Methods and compositions for treating inflammatory conditions
|
|
US20110251547A1
(en)
|
2008-11-07 |
2011-10-13 |
Intelligentnano Inc. |
Transfection with magnetic nanoparticles and ultrasound
|
|
US8679837B2
(en)
|
2009-04-02 |
2014-03-25 |
University Of Florida Research Foundation, Inc. |
Inducible system for highly efficient production of recombinant Adeno-associated virus (rAAV) vectors
|
|
JP5956331B2
(ja)
|
2009-06-16 |
2016-07-27 |
ジェンザイム・コーポレーション |
組換えａａｖベクターの改良された精製方法
|
|
EP2529020B1
(en)
|
2010-01-28 |
2018-04-25 |
The Children's Hospital of Philadelphia |
A scalable manufacturing platform for viral vector purification and viral vectors so purified for use in gene therapy
|
|
US20140359799A1
(en)
|
2011-12-23 |
2014-12-04 |
Case Western Reserve University |
Targeted gene modification using hybrid recombinant adeno-associated virus
|
|
DK2943567T3
(en)
|
2013-01-08 |
2018-01-02 |
Genzyme Corp |
USE OF INOS INHIBITORS TO INCREASE VIRAL YIELD IN CULTURE
|
|
AU2014216160B2
(en)
*
|
2013-02-15 |
2017-03-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
AAV8 retinoschisin expression vector for treating X-linked retinoschisis
|
|
JP6649265B2
(ja)
|
2013-11-26 |
2020-02-19 |
ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
糖原病の処置のためのアデノ随伴ウイルスベクター
|
|
EP3236984B1
(en)
|
2014-12-23 |
2020-07-22 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Adeno-associated virus vectors encoding modified g6pc and uses thereof
|
|
ES2938833T3
(es)
|
2016-03-28 |
2023-04-17 |
Ultragenyx Pharmaceutical Inc |
Métodos de inactivación térmica de adenovirus
|
|
EP3484493A4
(en)
|
2016-07-12 |
2019-12-25 |
Ultragenyx Pharmaceutical Inc. |
USE OF GLUCOCORTICOID ANALOGS TO INCREASE THE PERFORMANCE OF RECOMBINANT ADENO-ASSOCIATED VIRUSES
|
|
ES3012649T3
(en)
|
2016-10-14 |
2025-04-09 |
Ultragenyx Pharmaceutical Inc |
Use of tonicifying agents to enhance recombinant adeno-associated virus yield
|
|
AU2018212002A1
(en)
*
|
2017-01-30 |
2019-08-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Recombinant virus vectors for the treatment of glycogen storage disease
|
|
US20200048641A1
(en)
|
2017-03-22 |
2020-02-13 |
Ultragenyx Pharmaceutical Inc. |
Methods for enhancing yield of recombinant adeno-associated virus
|
|
EP3601581B1
(en)
|
2017-03-22 |
2025-04-30 |
Ultragenyx Pharmaceutical Inc. |
CELL CULTURE METHODS INVOLVING HDAC INHIBITORS OR REP PROTEINS
|
|
EP3621734A4
(en)
|
2017-05-09 |
2020-12-30 |
Ultragenyx Pharmaceutical Inc. |
MODULAR PROCESS FOR THE PRODUCTION OF TRANSFECTION REAGENTS
|