JP2022513658A5 - - Google Patents

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Publication number
JP2022513658A5
JP2022513658A5 JP2021530259A JP2021530259A JP2022513658A5 JP 2022513658 A5 JP2022513658 A5 JP 2022513658A5 JP 2021530259 A JP2021530259 A JP 2021530259A JP 2021530259 A JP2021530259 A JP 2021530259A JP 2022513658 A5 JP2022513658 A5 JP 2022513658A5
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JP
Japan
Prior art keywords
marker
methylation
max
dna
oligonucleotide
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JP2021530259A
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English (en)
Japanese (ja)
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JP7512278B2 (ja
JP2022513658A (ja
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Priority claimed from PCT/US2019/063401 external-priority patent/WO2020112869A1/en
Publication of JP2022513658A publication Critical patent/JP2022513658A/ja
Publication of JP2022513658A5 publication Critical patent/JP2022513658A5/ja
Priority to JP2024103130A priority Critical patent/JP2024123233A/ja
Application granted granted Critical
Publication of JP7512278B2 publication Critical patent/JP7512278B2/ja
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JP2021530259A 2018-11-27 2019-11-26 肺腫瘍の検出におけるメチル化dna、rna、及びタンパク質の特性決定 Active JP7512278B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024103130A JP2024123233A (ja) 2018-11-27 2024-06-26 肺腫瘍の検出におけるメチル化dna、rna、及びタンパク質の特性決定

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862771965P 2018-11-27 2018-11-27
US62/771,965 2018-11-27
PCT/US2019/063401 WO2020112869A1 (en) 2018-11-27 2019-11-26 Characterizing methylated dna, rna, and proteins in the detection of lung neoplasia

Related Child Applications (1)

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JP2024103130A Division JP2024123233A (ja) 2018-11-27 2024-06-26 肺腫瘍の検出におけるメチル化dna、rna、及びタンパク質の特性決定

Publications (3)

Publication Number Publication Date
JP2022513658A JP2022513658A (ja) 2022-02-09
JP2022513658A5 true JP2022513658A5 (enExample) 2022-12-06
JP7512278B2 JP7512278B2 (ja) 2024-07-08

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ID=70853661

Family Applications (2)

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JP2021530259A Active JP7512278B2 (ja) 2018-11-27 2019-11-26 肺腫瘍の検出におけるメチル化dna、rna、及びタンパク質の特性決定
JP2024103130A Pending JP2024123233A (ja) 2018-11-27 2024-06-26 肺腫瘍の検出におけるメチル化dna、rna、及びタンパク質の特性決定

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JP2024103130A Pending JP2024123233A (ja) 2018-11-27 2024-06-26 肺腫瘍の検出におけるメチル化dna、rna、及びタンパク質の特性決定

Country Status (10)

Country Link
US (1) US20220136058A1 (enExample)
EP (1) EP3886878A4 (enExample)
JP (2) JP7512278B2 (enExample)
KR (1) KR102945867B1 (enExample)
CN (1) CN113423410A (enExample)
AU (1) AU2019389008A1 (enExample)
BR (1) BR112021009795A2 (enExample)
CA (1) CA3119329A1 (enExample)
MX (1) MX2021005963A (enExample)
WO (1) WO2020112869A1 (enExample)

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EP2816122A1 (en) 2008-02-15 2014-12-24 Mayo Foundation For Medical Education And Research Detecting neoplasm from a stool sample
US8361720B2 (en) 2010-11-15 2013-01-29 Exact Sciences Corporation Real time cleavage assay
US8916344B2 (en) 2010-11-15 2014-12-23 Exact Sciences Corporation Methylation assay
CA2902916C (en) 2013-03-14 2018-08-28 Mayo Foundation For Medical Education And Research Detecting neoplasm
CN120700143A (zh) 2014-03-31 2025-09-26 梅奥医学教育和研究基金会 检测结直肠赘生物
US10184154B2 (en) 2014-09-26 2019-01-22 Mayo Foundation For Medical Education And Research Detecting cholangiocarcinoma
US10435755B2 (en) 2015-03-27 2019-10-08 Exact Sciences Development Company, Llc Detecting esophageal disorders
CN114574585A (zh) 2015-08-31 2022-06-03 梅约医药教育及研究基金会 检测胃肿瘤
CN108350485A (zh) 2015-10-30 2018-07-31 精密科学发展有限责任公司 血浆dna的多重扩增检测测定以及分离和检测
CN109563546B (zh) 2016-05-05 2022-09-09 精密科学发展有限责任公司 通过分析甲基化dna来检测肺肿瘤
KR102892245B1 (ko) 2017-01-27 2025-11-27 이그젝트 싸이언스 디블롭먼트 컴패니, 엘엘씨 메틸화된 dna 분석에 의한 결장 신조직형성의 검출
JP7277460B2 (ja) 2017-11-30 2023-05-19 マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチ 乳癌の検出
US10648025B2 (en) 2017-12-13 2020-05-12 Exact Sciences Development Company, Llc Multiplex amplification detection assay II
CA3127329A1 (en) 2019-01-24 2020-07-30 Mayo Foundation For Medical Education And Research Detecting endometrial cancer
CA3149601A1 (en) * 2019-08-27 2021-03-04 Scott Morris Characterizing methylated dna, rna, and proteins in subjects suspected of having lung neoplasia
EP4031683A4 (en) 2019-09-16 2024-01-17 Exact Sciences Corporation Structure and temperature-dependent flap endonuclease substrates
US11702704B2 (en) 2019-10-31 2023-07-18 Mayo Foundation For Medical Education And Research Detecting ovarian cancer
US11898199B2 (en) 2019-11-11 2024-02-13 Universal Diagnostics, S.A. Detection of colorectal cancer and/or advanced adenomas
US12467096B2 (en) 2020-05-15 2025-11-11 Universal Diagnostics, S.A. Methods and systems for identifying methylation biomarkers
EP4150121A1 (en) 2020-06-30 2023-03-22 Universal Diagnostics, S.A. Systems and methods for detection of multiple cancer types
EP3945135A1 (en) * 2020-07-27 2022-02-02 Les Laboratoires Servier Biomarkers for diagnosing and monitoring lung cancer
KR20230150814A (ko) * 2021-01-29 2023-10-31 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 다양한 유형의 암에 대한 존재 또는 부재의 검출
CN115505640B (zh) * 2021-06-22 2026-04-07 江苏鹍远生物科技股份有限公司 检测肺癌的dna甲基化标志物及应用
CN115725734B (zh) * 2022-08-10 2023-10-13 人和未来生物科技(长沙)有限公司 Znf781基因在制备宫颈癌诊断试剂中的应用
US12606872B2 (en) 2022-11-16 2026-04-21 Universal Diagnostics, S.A. Methods for stratification and early detection of advanced adenoma and/or colorectal cancer using DNA methylation markers
CN117683877A (zh) * 2023-12-19 2024-03-12 上海交通大学医学院 一种诊断或治疗免疫系统疾病的生物标志物或靶点

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070264659A1 (en) * 2006-05-11 2007-11-15 Sungwhan An Lung cancer biomarker discovery
JPWO2010064702A1 (ja) 2008-12-05 2012-05-10 国立大学法人 東京大学 癌の予後を予測するためのバイオマーカー
WO2010074924A1 (en) * 2008-12-23 2010-07-01 University Of Utah Research Foundation Identification and regulation of a novel dna demethylase system
EP2761025A1 (en) * 2011-09-30 2014-08-06 Genentech, Inc. Diagnostic methylation markers of epithelial or mesenchymal phenotype and response to egfr kinase inhibitor in tumours or tumour cells
WO2013070950A1 (en) * 2011-11-08 2013-05-16 University Of Southern California Identification of a dna methylation marker for blood-based detection of ovarian cancer
US9546403B1 (en) * 2011-12-14 2017-01-17 University Of Utah Research Foundation Substrate for methylated DNA testing
CA3183545C (en) * 2014-12-12 2026-01-13 Exact Sciences Corporation Compositions and methods for performing methylation detection assays
JP6877704B2 (ja) * 2015-11-16 2021-05-26 公立大学法人名古屋市立大学 膵臓癌の検出のための方法及びキット
CN109563546B (zh) * 2016-05-05 2022-09-09 精密科学发展有限责任公司 通过分析甲基化dna来检测肺肿瘤
WO2017223216A1 (en) * 2016-06-21 2017-12-28 The Wistar Institute Of Anatomy And Biology Compositions and methods for diagnosing lung cancers using gene expression profiles
EP3978624B1 (en) * 2016-07-19 2025-03-26 Exact Sciences Corporation Methylated control dna

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