MX2021005963A - Caracterizacion de adn metilado, arn y proteinas en la deteccion de neoplasia pulmonar. - Google Patents

Caracterizacion de adn metilado, arn y proteinas en la deteccion de neoplasia pulmonar.

Info

Publication number
MX2021005963A
MX2021005963A MX2021005963A MX2021005963A MX2021005963A MX 2021005963 A MX2021005963 A MX 2021005963A MX 2021005963 A MX2021005963 A MX 2021005963A MX 2021005963 A MX2021005963 A MX 2021005963A MX 2021005963 A MX2021005963 A MX 2021005963A
Authority
MX
Mexico
Prior art keywords
characterizing
rna
proteins
detection
methylated dna
Prior art date
Application number
MX2021005963A
Other languages
English (en)
Spanish (es)
Inventor
Hatim Allawi
Graham P Lidgard
Maria Giakoumopoulos
David A Ahlquist
William R Taylor
Douglas Mahoney
Original Assignee
Exact Sciences Dev Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exact Sciences Dev Co Llc filed Critical Exact Sciences Dev Co Llc
Publication of MX2021005963A publication Critical patent/MX2021005963A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
MX2021005963A 2018-11-27 2019-11-26 Caracterizacion de adn metilado, arn y proteinas en la deteccion de neoplasia pulmonar. MX2021005963A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862771965P 2018-11-27 2018-11-27
PCT/US2019/063401 WO2020112869A1 (en) 2018-11-27 2019-11-26 Characterizing methylated dna, rna, and proteins in the detection of lung neoplasia

Publications (1)

Publication Number Publication Date
MX2021005963A true MX2021005963A (es) 2021-08-24

Family

ID=70853661

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021005963A MX2021005963A (es) 2018-11-27 2019-11-26 Caracterizacion de adn metilado, arn y proteinas en la deteccion de neoplasia pulmonar.

Country Status (10)

Country Link
US (1) US20220136058A1 (enExample)
EP (1) EP3886878A4 (enExample)
JP (2) JP7512278B2 (enExample)
KR (1) KR20210099044A (enExample)
CN (1) CN113423410A (enExample)
AU (1) AU2019389008A1 (enExample)
BR (1) BR112021009795A2 (enExample)
CA (1) CA3119329A1 (enExample)
MX (1) MX2021005963A (enExample)
WO (1) WO2020112869A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2255198A4 (en) 2008-02-15 2011-05-25 Mayo Foundation DETECTION OF NEOPLASM
US8916344B2 (en) 2010-11-15 2014-12-23 Exact Sciences Corporation Methylation assay
US8361720B2 (en) 2010-11-15 2013-01-29 Exact Sciences Corporation Real time cleavage assay
WO2015153284A1 (en) 2014-03-31 2015-10-08 Mayo Foundation For Medical Education And Research Detecting colorectal neoplasm
US10184154B2 (en) 2014-09-26 2019-01-22 Mayo Foundation For Medical Education And Research Detecting cholangiocarcinoma
WO2016160454A1 (en) 2015-03-27 2016-10-06 Exact Sciences Corporation Detecting esophageal disorders
CA3002196C (en) 2015-10-30 2024-05-14 Exact Sciences Development Company, Llc Multiplex amplification detection assay and isolation and detection of dna from plasma
US10385406B2 (en) 2016-05-05 2019-08-20 Exact Sciences Development Company, Llc Detection of lung neoplasia by analysis of methylated DNA
KR102892245B1 (ko) 2017-01-27 2025-11-27 이그젝트 싸이언스 디블롭먼트 컴패니, 엘엘씨 메틸화된 dna 분석에 의한 결장 신조직형성의 검출
WO2019108626A1 (en) 2017-11-30 2019-06-06 Mayo Foundation For Medical Education And Research Detecting breast cancer
US10648025B2 (en) 2017-12-13 2020-05-12 Exact Sciences Development Company, Llc Multiplex amplification detection assay II
US20220403471A1 (en) * 2019-08-27 2022-12-22 Exact Sciences Corporation Characterizing methylated dna, rna, and proteins in subjects suspected of having lung neoplasia
CN114651070A (zh) 2019-09-16 2022-06-21 精密科学公司 结构和温度依赖性瓣状核酸内切酶底物
CA3154354A1 (en) 2019-10-31 2021-05-06 William R. Taylor Detecting ovarian cancer
US11898199B2 (en) 2019-11-11 2024-02-13 Universal Diagnostics, S.A. Detection of colorectal cancer and/or advanced adenomas
US12467096B2 (en) 2020-05-15 2025-11-11 Universal Diagnostics, S.A. Methods and systems for identifying methylation biomarkers
CN115997035A (zh) 2020-06-30 2023-04-21 通用诊断股份公司 用于检测多种癌症类型的系统和方法
EP3945135A1 (en) * 2020-07-27 2022-02-02 Les Laboratoires Servier Biomarkers for diagnosing and monitoring lung cancer
WO2022165247A1 (en) * 2021-01-29 2022-08-04 Mayo Foundation For Medical Education And Research Detecting the presence or absence of multiple types of cancer
CN115505640A (zh) * 2021-06-22 2022-12-23 上海鹍远生物科技股份有限公司 检测肺癌的dna甲基化标志物及应用
CN115725734B (zh) * 2022-08-10 2023-10-13 人和未来生物科技(长沙)有限公司 Znf781基因在制备宫颈癌诊断试剂中的应用
CN117683877A (zh) * 2023-12-19 2024-03-12 上海交通大学医学院 一种诊断或治疗免疫系统疾病的生物标志物或靶点

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070264659A1 (en) * 2006-05-11 2007-11-15 Sungwhan An Lung cancer biomarker discovery
WO2010064702A1 (ja) 2008-12-05 2010-06-10 国立大学法人 東京大学 癌の予後を予測するためのバイオマーカー
WO2010074924A1 (en) * 2008-12-23 2010-07-01 University Of Utah Research Foundation Identification and regulation of a novel dna demethylase system
JP2014531213A (ja) * 2011-09-30 2014-11-27 ジェネンテック, インコーポレイテッド 上皮又は間葉の表現型の診断用メチル化マーカー、及び腫瘍又は腫瘍細胞におけるegfrキナーゼ阻害薬に対する応答
WO2013070950A1 (en) * 2011-11-08 2013-05-16 University Of Southern California Identification of a dna methylation marker for blood-based detection of ovarian cancer
US9546403B1 (en) * 2011-12-14 2017-01-17 University Of Utah Research Foundation Substrate for methylated DNA testing
US10465248B2 (en) * 2014-12-12 2019-11-05 Exact Sciences Development Company, Llc Method of characterizing ZDHHC1 DNA
JP6877704B2 (ja) * 2015-11-16 2021-05-26 公立大学法人名古屋市立大学 膵臓癌の検出のための方法及びキット
US10385406B2 (en) * 2016-05-05 2019-08-20 Exact Sciences Development Company, Llc Detection of lung neoplasia by analysis of methylated DNA
AU2017281099A1 (en) * 2016-06-21 2019-01-03 The Wistar Institute Of Anatomy And Biology Compositions and methods for diagnosing lung cancers using gene expression profiles
WO2018017740A1 (en) * 2016-07-19 2018-01-25 Exact Sciences Development Company, Llc Methylated control dna

Also Published As

Publication number Publication date
BR112021009795A2 (pt) 2021-08-17
CA3119329A1 (en) 2020-06-04
EP3886878A1 (en) 2021-10-06
JP2022513658A (ja) 2022-02-09
JP2024123233A (ja) 2024-09-10
US20220136058A1 (en) 2022-05-05
KR20210099044A (ko) 2021-08-11
JP7512278B2 (ja) 2024-07-08
EP3886878A4 (en) 2022-11-02
WO2020112869A1 (en) 2020-06-04
AU2019389008A1 (en) 2021-06-03
CN113423410A (zh) 2021-09-21

Similar Documents

Publication Publication Date Title
MX2021005963A (es) Caracterizacion de adn metilado, arn y proteinas en la deteccion de neoplasia pulmonar.
AU2020336115A8 (en) Characterizing methylated DNA, RNA, and proteins in subjects suspected of having lung neoplasia
AU2017260630A1 (en) Detection of lung neoplasia by analysis of methylated DNA
EP4234722A3 (en) Detecting colorectal neoplasm
PH12019502171A1 (en) Composition and methods for immunooncology
PH12018501159A1 (en) Composition and methods for immunooncology
EA201201000A1 (ru) Способы лечения колоректального рака
WO2014159650A3 (en) Detecting neoplasm
EP3971299A3 (en) Colorectal cancer detection kit or device, and detection method
EP3862439A3 (en) Liver cancer detection kit or device, and detection method
AU2015205612A8 (en) Method for generating double stranded DNA libraries and sequencing methods for the identification of methylated cytosines
MD20150100A2 (ro) Virusurile bolii de Newcastle şi utilizarea acestora
GB2539350A (en) Amyloid targeting agents and methods of using the same
MX386750B (es) MARCADORES DE METILACIÓN Y DE miARN PARA LA DETECCIÓN DE CÁNCER.
GB2526736A (en) Methods, compositions, and kits for nucleic acid analysis
BR112015009752A2 (pt) conjugados de anticorpo/fármaco e métodos de uso
EP3800253A3 (en) Prostate cancer detection kit or device, and detection method
BR112017016897A2 (pt) cepas fúngicas e métodos de uso
AR093446A1 (es) Anticuerpos de antihemaglutinina y metodos de uso
EA201390695A1 (ru) Способы лечения рака
BR112018010279A2 (pt) novos anticorpos anti-emr2 e métodos de uso
WO2015051320A3 (en) Anti-sox10 antibody systems and methods
EP4053146A3 (en) Molecule sensor systems
WO2014197835A3 (en) Methods and compositions for the treatment of cancer
WO2012154983A3 (en) Systems and methods for anti-pax8 antibodies