JP2022512736A5 - - Google Patents
Info
- Publication number
- JP2022512736A5 JP2022512736A5 JP2021521145A JP2021521145A JP2022512736A5 JP 2022512736 A5 JP2022512736 A5 JP 2022512736A5 JP 2021521145 A JP2021521145 A JP 2021521145A JP 2021521145 A JP2021521145 A JP 2021521145A JP 2022512736 A5 JP2022512736 A5 JP 2022512736A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- compound according
- mol
- deuterium
- structural formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024107578A JP2024150488A (ja) | 2018-10-18 | 2024-07-03 | 重水素を含有する化合物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1816998.7A GB201816998D0 (en) | 2018-10-18 | 2018-10-18 | Compounds |
| GB1816998.7 | 2018-10-18 | ||
| GBGB1909695.7A GB201909695D0 (en) | 2019-07-05 | 2019-07-05 | Compounds |
| GB1909695.7 | 2019-07-05 | ||
| PCT/EP2019/078250 WO2020079165A1 (en) | 2018-10-18 | 2019-10-17 | Compounds containing deuterium |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024107578A Division JP2024150488A (ja) | 2018-10-18 | 2024-07-03 | 重水素を含有する化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022512736A JP2022512736A (ja) | 2022-02-07 |
| JP2022512736A5 true JP2022512736A5 (enExample) | 2022-10-18 |
| JP7603199B2 JP7603199B2 (ja) | 2024-12-20 |
Family
ID=68290247
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021521145A Active JP7603199B2 (ja) | 2018-10-18 | 2019-10-17 | 重水素を含有する化合物 |
| JP2024107578A Pending JP2024150488A (ja) | 2018-10-18 | 2024-07-03 | 重水素を含有する化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024107578A Pending JP2024150488A (ja) | 2018-10-18 | 2024-07-03 | 重水素を含有する化合物 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US12152087B2 (enExample) |
| EP (1) | EP3866931B1 (enExample) |
| JP (2) | JP7603199B2 (enExample) |
| KR (1) | KR102848971B1 (enExample) |
| CN (1) | CN112930214B (enExample) |
| AU (1) | AU2019362389B2 (enExample) |
| BR (1) | BR112021007060A2 (enExample) |
| CA (1) | CA3116198A1 (enExample) |
| DK (1) | DK3866931T3 (enExample) |
| ES (1) | ES2942468T3 (enExample) |
| FI (1) | FI3866931T3 (enExample) |
| HU (1) | HUE061801T2 (enExample) |
| IL (1) | IL282231B2 (enExample) |
| MA (1) | MA53904A (enExample) |
| MX (1) | MX2021004474A (enExample) |
| PL (1) | PL3866931T3 (enExample) |
| SG (1) | SG11202103726RA (enExample) |
| WO (1) | WO2020079165A1 (enExample) |
| ZA (1) | ZA202102492B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201905477D0 (en) * | 2019-04-17 | 2019-05-29 | Oncopeptides Ab | Novel formulations |
| ES3034388T3 (en) * | 2021-06-01 | 2025-08-18 | Synthon Bv | Process for making melflufen or a salt thereof |
| JP2024524552A (ja) | 2021-07-08 | 2024-07-05 | オンコペプティデス エービー | 多発性骨髄腫の治療に使用するためのメルフルフェン |
| GB202109894D0 (en) | 2021-07-08 | 2021-08-25 | Oncopeptides Ab | Novel treatments |
| GB202109896D0 (en) | 2021-07-08 | 2021-08-25 | Oncopeptides Ab | Novel treatments |
| GB202109895D0 (en) | 2021-07-08 | 2021-08-25 | Oncopeptides Ab | Novel treatments |
| GB202204171D0 (en) | 2022-03-24 | 2022-05-11 | Oncopeptides Ab | Novel formulations |
| WO2026057823A1 (en) * | 2024-09-13 | 2026-03-19 | Oncopeptides Ab | Bis-chloroethylamino derivatives for treating leukemia |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0002202D0 (sv) | 2000-06-13 | 2000-06-13 | Karolinska Innovations Ab | New peptides |
| CA2972242A1 (en) | 2008-09-18 | 2010-04-22 | Auspex Pharmaceuticals, Inc. | Benzoquinoline inhibitors of vesicular monoamine transporter 2 |
| EP3351247A1 (en) | 2010-06-01 | 2018-07-25 | Auspex Pharmaceutical, Inc. | Benzoquinolone inhibitors of vmat2 |
| DK2701720T3 (en) * | 2011-04-28 | 2017-10-09 | Oncopeptides Ab | Lyophilized preparation with cytotoxic dipeptides |
| EP4345100A3 (en) | 2012-09-18 | 2024-04-10 | Auspex Pharmaceuticals, Inc. | Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2 |
| SMT202000058T1 (it) * | 2012-10-26 | 2020-03-13 | Oncopeptides Ab | Preparazioni liofilizzate di melfalan flufenammide |
| JP2016506957A (ja) | 2013-01-31 | 2016-03-07 | オースペックス・ファーマシューティカルズ・インコーポレイテッドＡｕｓｐｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | Ｖｍａｔ２のベンゾキノロン阻害剤 |
| ES2901752T3 (es) * | 2013-02-05 | 2022-03-23 | Teva Pharmaceuticals Int Gmbh | Derivados de catecolamina enriquecidos con deuterio asimétrico de posición específica y medicamentos que comprenden dichos compuestos |
| WO2015084622A1 (en) | 2013-12-03 | 2015-06-11 | Auspex Pharmaceuticals, Inc. | Methods of manufacturing benzoquinoline compounds |
| CN110229159B (zh) | 2013-12-18 | 2021-08-24 | 康塞特医药品有限公司 | 卢索替尼的氘代衍生物 |
| AU2016229949B2 (en) | 2015-03-06 | 2021-04-08 | Auspex Pharmaceuticals Llc | Methods for the treatment of abnormal involuntary movement disorders |
| GB201507903D0 (en) | 2015-05-08 | 2015-06-24 | Oncopeptides Ab | Process for preparation of nitrogen mustard derivatives |
| GB201521217D0 (en) * | 2015-12-01 | 2016-01-13 | Oncopeptides Ab | Dosage regimens |
-
2019
- 2019-10-17 US US17/286,002 patent/US12152087B2/en active Active
- 2019-10-17 SG SG11202103726RA patent/SG11202103726RA/en unknown
- 2019-10-17 WO PCT/EP2019/078250 patent/WO2020079165A1/en not_active Ceased
- 2019-10-17 HU HUE19790194A patent/HUE061801T2/hu unknown
- 2019-10-17 FI FIEP19790194.5T patent/FI3866931T3/fi active
- 2019-10-17 MX MX2021004474A patent/MX2021004474A/es unknown
- 2019-10-17 MA MA053904A patent/MA53904A/fr unknown
- 2019-10-17 IL IL282231A patent/IL282231B2/en unknown
- 2019-10-17 DK DK19790194.5T patent/DK3866931T3/da active
- 2019-10-17 KR KR1020217011490A patent/KR102848971B1/ko active Active
- 2019-10-17 CN CN201980068384.1A patent/CN112930214B/zh active Active
- 2019-10-17 EP EP19790194.5A patent/EP3866931B1/en active Active
- 2019-10-17 ES ES19790194T patent/ES2942468T3/es active Active
- 2019-10-17 PL PL19790194.5T patent/PL3866931T3/pl unknown
- 2019-10-17 JP JP2021521145A patent/JP7603199B2/ja active Active
- 2019-10-17 CA CA3116198A patent/CA3116198A1/en active Pending
- 2019-10-17 AU AU2019362389A patent/AU2019362389B2/en active Active
- 2019-10-17 BR BR112021007060-5A patent/BR112021007060A2/pt unknown
-
2021
- 2021-04-15 ZA ZA2021/02492A patent/ZA202102492B/en unknown
-
2024
- 2024-07-03 JP JP2024107578A patent/JP2024150488A/ja active Pending
- 2024-10-16 US US18/917,773 patent/US20250115637A1/en active Pending
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