JP2022508642A5 - - Google Patents

Info

Publication number
JP2022508642A5
JP2022508642A5 JP2021544096A JP2021544096A JP2022508642A5 JP 2022508642 A5 JP2022508642 A5 JP 2022508642A5 JP 2021544096 A JP2021544096 A JP 2021544096A JP 2021544096 A JP2021544096 A JP 2021544096A JP 2022508642 A5 JP2022508642 A5 JP 2022508642A5
Authority
JP
Japan
Prior art keywords
independently
heteroatoms
membered
ring containing
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021544096A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022508642A (ja
JP7648528B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/054790 external-priority patent/WO2020072955A1/en
Publication of JP2022508642A publication Critical patent/JP2022508642A/ja
Publication of JP2022508642A5 publication Critical patent/JP2022508642A5/ja
Priority to JP2024179311A priority Critical patent/JP2025020149A/ja
Application granted granted Critical
Publication of JP7648528B2 publication Critical patent/JP7648528B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021544096A 2018-10-05 2019-10-04 モノマーおよびマルチマー抗hbv薬 Active JP7648528B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024179311A JP2025020149A (ja) 2018-10-05 2024-10-11 モノマーおよびマルチマー抗hbv薬

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862741822P 2018-10-05 2018-10-05
US62/741,822 2018-10-05
PCT/US2019/054790 WO2020072955A1 (en) 2018-10-05 2019-10-04 Monomer and multimeric anti-hbv agents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024179311A Division JP2025020149A (ja) 2018-10-05 2024-10-11 モノマーおよびマルチマー抗hbv薬

Publications (3)

Publication Number Publication Date
JP2022508642A JP2022508642A (ja) 2022-01-19
JP2022508642A5 true JP2022508642A5 (enExample) 2023-06-27
JP7648528B2 JP7648528B2 (ja) 2025-03-18

Family

ID=70055532

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021544096A Active JP7648528B2 (ja) 2018-10-05 2019-10-04 モノマーおよびマルチマー抗hbv薬
JP2024179311A Pending JP2025020149A (ja) 2018-10-05 2024-10-11 モノマーおよびマルチマー抗hbv薬

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024179311A Pending JP2025020149A (ja) 2018-10-05 2024-10-11 モノマーおよびマルチマー抗hbv薬

Country Status (14)

Country Link
US (1) US20230056135A1 (enExample)
EP (1) EP3860991A4 (enExample)
JP (2) JP7648528B2 (enExample)
KR (2) KR20210072015A (enExample)
CN (2) CN122404196A (enExample)
AU (1) AU2019355218B2 (enExample)
BR (1) BR112021006403A2 (enExample)
CA (1) CA3113109A1 (enExample)
IL (2) IL328538A (enExample)
MX (1) MX2021003150A (enExample)
PH (1) PH12021550632A1 (enExample)
SG (1) SG11202102661UA (enExample)
WO (1) WO2020072955A1 (enExample)
ZA (1) ZA202102589B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL328538A (en) * 2018-10-05 2026-07-01 Univ Emory Monomeric and multimeric hepatitis B antivirals
IL286902B2 (en) 2019-04-03 2025-03-01 Aligos Therapeutics Inc Pyrrole compounds
KR20230021121A (ko) * 2020-06-05 2023-02-13 파티오스 테라퓨틱스 리미티드 Gpr65의 조절제로서 n-페닐아미노카보닐 피리디노-, 피리미디노 및 벤조-트로판
WO2022156758A1 (zh) * 2021-01-22 2022-07-28 广东东阳光药业有限公司 新型酰胺吡咯类化合物及其在药物中的用途
WO2023174351A1 (zh) * 2022-03-17 2023-09-21 成都微芯药业有限公司 吡咯酰胺类化合物及其制备方法和用途
CN116120219A (zh) * 2022-12-27 2023-05-16 吉斯凯(苏州)制药有限公司 一种多取代吡咯类化合物及其制备方法和在制备hbv衣壳蛋白抑制剂中的应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP913999A0 (en) * 1999-03-12 1999-04-01 Biota Scientific Management Pty Ltd Novel chemical compounds and their use
US20060100233A1 (en) * 2002-07-25 2006-05-11 Manuela Villa Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
US9242981B2 (en) * 2010-09-16 2016-01-26 Merck Sharp & Dohme Corp. Fused pyrazole derivatives as novel ERK inhibitors
WO2013006394A1 (en) * 2011-07-01 2013-01-10 Institute For Hepatitis And Virus Research Sulfamoylbenzamide derivatives as antiviral agents against hbv infection
CA2881057C (en) * 2012-08-28 2020-10-27 Janssen Sciences Ireland Uc Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis b
HK1215030A1 (zh) * 2012-11-09 2016-08-12 Indiana University Research And Technology Corporation 用於hbv組裝效應劑的替代用途
HK1217649A1 (zh) * 2012-12-27 2017-01-20 德雷克塞尔大学 針對hbv感染的新型抗病毒劑
WO2015011281A1 (en) * 2013-07-25 2015-01-29 Janssen R&D Ireland Glyoxamide substituted pyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
EP3150600B1 (en) * 2014-05-30 2018-06-27 Qilu Pharmaceutical Co., Ltd. Dihydropyrimido loop derivative as hbv inhibitor
WO2016109689A2 (en) * 2014-12-30 2016-07-07 Novira Therapeutics, Inc. Derivatives and methods of treating hepatitis b infections
CN106317055A (zh) * 2015-07-02 2017-01-11 中国科学院上海药物研究所 一类具有激酶抑制活性的化合物、制备方法和用途
BR112018068177B1 (pt) * 2016-03-09 2024-02-27 Emory University Composto, uso do composto e composição para eliminação do vírus da hepatite b com agentes antivirais
JOP20190024A1 (ar) 2016-08-26 2019-02-19 Gilead Sciences Inc مركبات بيروليزين بها استبدال واستخداماتها
WO2019185016A1 (zh) 2018-03-30 2019-10-03 正大天晴药业集团股份有限公司 含有n杂五元环的衣壳蛋白装配抑制剂、其药物组合物和用途
WO2019241292A1 (en) 2018-06-11 2019-12-19 VenatoRx Pharmaceuticals, Inc. Hepatitis b capsid assembly modulators
WO2020001592A1 (zh) * 2018-06-28 2020-01-02 河南天晟泰丰医药科技有限公司 二氢嘧啶衍生物及其用途
IL328538A (en) * 2018-10-05 2026-07-01 Univ Emory Monomeric and multimeric hepatitis B antivirals

Similar Documents

Publication Publication Date Title
JP2019507774A5 (enExample)
JP2023500328A5 (enExample)
JP2024543976A5 (enExample)
WO2018013597A4 (en) 2,5-disubstituted 3-methyl pyrazines and 2,5,6-trisubstituted 3-methyl pyrazines as allosteric shp2 inhibitors
RU2419626C2 (ru) Соединения и композиции в качестве ингибиторов протеазы, активирующей каналы
JP2022505987A5 (enExample)
RU2020123241A (ru) Полициклические соединения в качестве аллостерических ингибиторов shp2
JP2014520822A5 (enExample)
RU2010136665A (ru) Новые пиридиноны и пиридазиноны
RU2009102252A (ru) Хиноксалинилмакроциклические ингибиторы серинпротеазы вируса гепатита с
ATE12492T1 (de) Aryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
JP2016509591A5 (enExample)
EA200900358A1 (ru) Энантиомерно чистые фосфоиндолы в качестве ингибиторов hiv
RU2008136187A (ru) Новое производное кумарина, обладающее противоопухолевой активностью
JP2008510691A5 (enExample)
AR060994A1 (es) Derivados de triazolopirazina
RU2017145650A (ru) Ингибиторы тирозинкиназы брутона
JP2018502891A5 (enExample)
AR058379A1 (es) Derivados de arilpropionamida arilacrilamida arilpropinamida o arilmetilurea como inhibidores del factor xia. proceso de obtencion y composiciones farmaceuticas.
RU2010100945A (ru) Способы и композиции для стимулирования нейрогенеза и ингибирования дегенерации нейронов с использованием изотиазолопиримидинонов
RU2011108008A (ru) Производные трициклического алкиламинометилоксазолидинона
JP2003515523A5 (enExample)
RU2015104969A (ru) Производные пиридинона в качестве ингибиторов трансглутаминазы тканей
JP2022548247A5 (enExample)
RU2014122866A (ru) Пропеноатные производные бетулина