JP2022501049A5 - - Google Patents
Info
- Publication number
- JP2022501049A5 JP2022501049A5 JP2021516628A JP2021516628A JP2022501049A5 JP 2022501049 A5 JP2022501049 A5 JP 2022501049A5 JP 2021516628 A JP2021516628 A JP 2021516628A JP 2021516628 A JP2021516628 A JP 2021516628A JP 2022501049 A5 JP2022501049 A5 JP 2022501049A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- positive
- aggregates
- inhibitor
- pluripotent stem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024169082A JP2024178446A (ja) | 2018-09-19 | 2024-09-27 | 動的懸濁培養において多能性幹細胞を分化させるための方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862733621P | 2018-09-19 | 2018-09-19 | |
| US62/733,621 | 2018-09-19 | ||
| PCT/US2019/052015 WO2020061371A2 (en) | 2018-09-19 | 2019-09-19 | Methods for differentiating pluripotent stem cells in dynamic suspension culture |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024169082A Division JP2024178446A (ja) | 2018-09-19 | 2024-09-27 | 動的懸濁培養において多能性幹細胞を分化させるための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022501049A JP2022501049A (ja) | 2022-01-06 |
| JP2022501049A5 true JP2022501049A5 (cg-RX-API-DMAC7.html) | 2022-09-20 |
| JP7569089B2 JP7569089B2 (ja) | 2024-10-17 |
Family
ID=69772854
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021516628A Active JP7569089B2 (ja) | 2018-09-19 | 2019-09-19 | 動的懸濁培養において多能性幹細胞を分化させるための方法 |
| JP2024169082A Pending JP2024178446A (ja) | 2018-09-19 | 2024-09-27 | 動的懸濁培養において多能性幹細胞を分化させるための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024169082A Pending JP2024178446A (ja) | 2018-09-19 | 2024-09-27 | 動的懸濁培養において多能性幹細胞を分化させるための方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US12365872B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3853345A4 (cg-RX-API-DMAC7.html) |
| JP (2) | JP7569089B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20210068050A (cg-RX-API-DMAC7.html) |
| CN (2) | CN120060140A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2019342741B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3113640A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL281628B2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2020061371A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3019514A1 (en) | 2016-03-30 | 2017-10-05 | Asterias Biotherapeutics, Inc. | Oligodendrocyte progenitor cell compositions |
| AU2019342741B2 (en) * | 2018-09-19 | 2025-12-11 | Lineage Cell Therapeutics, Inc. | Methods for differentiating pluripotent stem cells in dynamic suspension culture |
| AU2020210757B2 (en) * | 2019-01-23 | 2026-04-16 | Asterias Biotherapeutics, Inc. | Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells |
| US12533383B2 (en) | 2019-09-06 | 2026-01-27 | Keio University | Method for producing cell aggregate including glial progenitor cells |
| EP4269564A4 (en) * | 2020-12-25 | 2025-03-05 | Iregene Therapeutics Ltd | CHEMICAL INDUCTION METHOD FOR PHOTORECEPTOR NEURONAL CELLS |
| CN112640887B (zh) * | 2020-12-25 | 2022-05-13 | 武汉睿健医药科技有限公司 | 一种神经干细胞冻存液及其应用 |
| KR20230154071A (ko) * | 2021-03-10 | 2023-11-07 | 리니지 셀 테라퓨틱스, 인크. | 희소돌기아교세포 전구 세포의 생성 방법 및 이의 용도 |
| EP4314256A1 (en) | 2021-03-30 | 2024-02-07 | Trailhead Biosystems Inc. | Methods and compositions for generating oligodendrocyte progenitor cells |
| US20230190961A1 (en) * | 2021-10-20 | 2023-06-22 | University Of Rochester | Compositions and methods for treating myelin deficiency by rejuvenating glial progenitor cells |
| CA3256595A1 (en) * | 2022-05-24 | 2023-11-30 | Bluerock Therapeutics Lp | METHODS FOR MANUFACTURED OLIGODENDROCYTE PROGENITOR CELLS |
| CN119654404A (zh) * | 2022-08-08 | 2025-03-18 | 特雷尔赫德生物系统股份有限公司 | 产生少突胶质祖细胞的方法和组合物 |
| WO2025171344A1 (en) * | 2024-02-09 | 2025-08-14 | Cedars-Sinai Medical Center | Expansion, harvest and cryopreservation of induced pluripotent stem cells with cgmps |
| CN120081923B (zh) * | 2025-04-28 | 2025-08-01 | 四川华德生物工程有限公司 | 一种动物源表皮生长因子的智能优化方法和系统 |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998048001A1 (en) | 1997-04-24 | 1998-10-29 | California Institute Of Technology | Methods for differentiating neural stem cells |
| US6361996B1 (en) | 1997-05-07 | 2002-03-26 | University Of Utah Research Foundation | Neuroepithelial stem cells and glial-restricted intermediate precursors |
| CA2388736A1 (en) | 1999-10-22 | 2001-04-26 | Washington University | Oligodendrocyte cell cultures and methods for their preparation and use |
| US6280718B1 (en) | 1999-11-08 | 2001-08-28 | Wisconsin Alumni Reasearch Foundation | Hematopoietic differentiation of human pluripotent embryonic stem cells |
| WO2001068815A1 (en) | 2000-03-14 | 2001-09-20 | Es Cell International Pte Ltd | Embryonic stem cells and neural progenitor cells derived therefrom |
| EP1287116A2 (en) | 2000-05-17 | 2003-03-05 | Geron Corporation | Neural progenitor cell populations |
| US20030223972A1 (en) | 2002-02-15 | 2003-12-04 | Goldman Steven A. | Myelination of congenitally dysmyelinated forebrains using oligodendrocyte progenitor cells |
| US20050101014A1 (en) | 2002-07-11 | 2005-05-12 | Keirstead Hans S. | Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury |
| US7285415B2 (en) | 2002-07-11 | 2007-10-23 | The Regents Of The University Of California | Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury |
| US7390659B2 (en) | 2002-07-16 | 2008-06-24 | The Trustees Of Columbia University In The City Of New York | Methods for inducing differentiation of embryonic stem cells and uses thereof |
| ES2569780T3 (es) | 2003-06-27 | 2016-05-12 | DePuy Synthes Products, Inc. | Células posparto derivadas de tejido placentario y métodos de preparación y uso de las mismas |
| AR046076A1 (es) | 2003-07-18 | 2005-11-23 | Otsuka Pharma Co Ltd | Procedimiento para obtener una poblacion homogenea de celulas precursoras de oligodendrocitos y poblacion obtenida |
| WO2006055685A2 (en) | 2004-11-17 | 2006-05-26 | Neuralstem, Inc. | Transplantation of human neural cells for treatment of neurodegenerative conditions |
| US8709797B2 (en) | 2006-06-20 | 2014-04-29 | Cook General Biotechnology Llc | Systems and methods for cryopreservation of cells |
| EP2061440A2 (en) | 2007-04-04 | 2009-05-27 | Sigmoid Pharma Limited | A pharmaceutical composition of tacrolimus |
| EP2139497B1 (en) * | 2007-04-13 | 2013-11-06 | Stemnion, INC. | Methods for treating nervous system injury and disease |
| EP2028268A1 (en) | 2007-08-20 | 2009-02-25 | Université Libre De Bruxelles | Generation of neuronal cells from pluripotent stem cells |
| KR100941036B1 (ko) | 2007-10-05 | 2010-02-05 | 고려대학교 산학협력단 | 인간 배아줄기세포로부터 척수신경계 희소돌기 아교세포생산을 위한 삼단계 분화기법 |
| WO2009057111A2 (en) | 2007-10-29 | 2009-05-07 | Hadasit Medical Research Services & Development Limited | Human stem cell-derived neural precursors for treatment of autoimmune diseases of the central nervous system |
| US8227247B2 (en) | 2007-12-20 | 2012-07-24 | Wisconsin Alumni Research Foundation | Method of generating myelinating oligodendrocytes |
| CN101939362A (zh) | 2008-01-30 | 2011-01-05 | 杰龙公司 | 用于培养干细胞衍生的少突胶质细胞前体细胞的合成表面 |
| US9709553B2 (en) | 2008-05-08 | 2017-07-18 | University Of Rochester | Treating myelin diseases with optimized cell preparations |
| EP2283115A1 (en) | 2008-05-09 | 2011-02-16 | The University Court Of The University Of Glasgow | Materials and methods relating to cell based therapies |
| CN102325878A (zh) | 2008-12-23 | 2012-01-18 | 斯特姆塞尔思加利福尼亚有限公司 | 少突胶质前体细胞的靶向细胞群及制备与使用方法 |
| US8642334B2 (en) | 2009-02-17 | 2014-02-04 | Memorial Sloan Kettering Cancer Center | Methods of neural conversion of human embryonic stem cells |
| CA2766164A1 (en) | 2009-06-25 | 2010-12-29 | Geron Corporation | Differentiated pluripotent stem cell progeny depleted of extraneous phenotypes |
| EP2499241B8 (en) | 2009-11-10 | 2018-02-21 | The J. David Gladstone Institutes | Methods of generating neural stem cells |
| CN102160546B (zh) | 2010-02-24 | 2016-01-20 | 库克通用生物科技有限责任公司 | 冷冻保存细胞的系统和方法 |
| WO2012021818A2 (en) | 2010-08-13 | 2012-02-16 | Georgetown University | Ggf2 and methods of use |
| US9193951B2 (en) | 2010-10-26 | 2015-11-24 | Case Western Reserve University | Differentiation method for production of glial cell populations |
| KR101921350B1 (ko) | 2010-12-17 | 2018-11-22 | 바이오라미나 에이비 | 인간 다능성 줄기세포를 유지하기 위한 시스템 |
| CN109749996A (zh) * | 2011-01-12 | 2019-05-14 | 城户常雄 | 获得和维持纯化或富集的哺乳动物神经干细胞群和/或神经祖细胞群的培养方法 |
| JP6204976B2 (ja) | 2012-05-16 | 2017-09-27 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 多能性幹細胞由来の細胞培養物からニューロンを単離するための細胞表面特性 |
| CA2896442A1 (en) | 2012-09-24 | 2014-03-27 | The Regents Of The University Of California | Spinal cord pulsation-cancelation injection system |
| EP3766962B1 (en) | 2013-02-06 | 2025-10-22 | University of Rochester | Induced pluripotent cell-derived oligodendrocyte progenitor cells for the treatment of myelin disorders |
| US10160950B2 (en) | 2013-03-01 | 2018-12-25 | Wisconsin Alumni Research Foundation | Methods of maintaining, expanding and differentiating neuronal subtype specific progenitors |
| US20140248696A1 (en) | 2013-03-01 | 2014-09-04 | Wisconsin Alumni Research Foundation | Methods of maintaining, expanding, and diffrentiating neuronal subtype specific progenitors |
| CA2906815A1 (en) | 2013-03-15 | 2014-09-18 | Ocata Therapeutics, Inc. | Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells |
| WO2015088625A2 (en) * | 2013-09-25 | 2015-06-18 | Case Western Reserve University | Compounds and methods of promoting myelination |
| US9694036B2 (en) | 2014-03-21 | 2017-07-04 | Cellular Dynamics International, Inc. | Production of midbrain dopaminergic neurons and methods for the use thereof |
| JP6873705B2 (ja) | 2014-05-22 | 2021-05-19 | ニューヨーク ステム セル ファウンデーション インコーポレイテッド | 多能性幹細胞由来の機能性オリゴデンドロサイト、ならびにその作製方法及び使用方法 |
| CN113564123B (zh) | 2014-10-24 | 2024-11-15 | 住友制药株式会社 | 神经组织的制备方法 |
| CN105624116B (zh) | 2014-11-07 | 2020-04-07 | 中国科学院上海生命科学研究院 | 利用多能干细胞制备神经前体细胞的方法 |
| WO2016103269A1 (en) | 2014-12-23 | 2016-06-30 | Ramot At Tel-Aviv University Ltd. | Populations of neural progenitor cells and methods of producing and using same |
| US10286009B2 (en) | 2015-05-16 | 2019-05-14 | Asterias Biotherapeutics, Inc. | Pluripotent stem cell-derived oligodendrocyte progenitor cells for the treatment of spinal cord injury |
| EP3448985A4 (en) | 2016-01-27 | 2019-08-21 | Memorial Sloan-Kettering Cancer Center | DIFFERENTIATION OF CORTIC NEURONS FROM HUMAN PLURIPOTENTIAL STEM CELLS |
| CA3019514A1 (en) * | 2016-03-30 | 2017-10-05 | Asterias Biotherapeutics, Inc. | Oligodendrocyte progenitor cell compositions |
| US20190262405A1 (en) | 2016-09-14 | 2019-08-29 | Asterias Biotherapeutics, Inc. | Pluripotent stem cell-derived oligodendrocyte progenitor cells for the treatment of spinal cord injury |
| AU2019342741B2 (en) | 2018-09-19 | 2025-12-11 | Lineage Cell Therapeutics, Inc. | Methods for differentiating pluripotent stem cells in dynamic suspension culture |
| AU2020210757B2 (en) | 2019-01-23 | 2026-04-16 | Asterias Biotherapeutics, Inc. | Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells |
-
2019
- 2019-09-19 AU AU2019342741A patent/AU2019342741B2/en active Active
- 2019-09-19 JP JP2021516628A patent/JP7569089B2/ja active Active
- 2019-09-19 WO PCT/US2019/052015 patent/WO2020061371A2/en not_active Ceased
- 2019-09-19 CA CA3113640A patent/CA3113640A1/en active Pending
- 2019-09-19 CN CN202510192544.0A patent/CN120060140A/zh active Pending
- 2019-09-19 CN CN201980070640.0A patent/CN113646422B/zh active Active
- 2019-09-19 US US17/277,548 patent/US12365872B2/en active Active
- 2019-09-19 US US16/576,627 patent/US20200087622A1/en not_active Abandoned
- 2019-09-19 KR KR1020217011488A patent/KR20210068050A/ko active Pending
- 2019-09-19 EP EP19862819.0A patent/EP3853345A4/en active Pending
- 2019-09-19 IL IL281628A patent/IL281628B2/en unknown
-
2024
- 2024-09-27 JP JP2024169082A patent/JP2024178446A/ja active Pending
-
2025
- 2025-06-11 US US19/235,019 patent/US20260002126A1/en active Pending
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