JP2022105084A5 - - Google Patents
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- JP2022105084A5 JP2022105084A5 JP2022072043A JP2022072043A JP2022105084A5 JP 2022105084 A5 JP2022105084 A5 JP 2022105084A5 JP 2022072043 A JP2022072043 A JP 2022072043A JP 2022072043 A JP2022072043 A JP 2022072043A JP 2022105084 A5 JP2022105084 A5 JP 2022105084A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- disease
- acid sequence
- amino acid
- autoimmune
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023209102A JP7823011B2 (ja) | 2015-03-09 | 2023-12-12 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
| JP2025174910A JP2026012786A (ja) | 2015-03-09 | 2025-10-16 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562130076P | 2015-03-09 | 2015-03-09 | |
| US62/130,076 | 2015-03-09 | ||
| JP2022051047A JP7391132B2 (ja) | 2015-03-09 | 2022-03-28 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022051047A Division JP7391132B2 (ja) | 2015-03-09 | 2022-03-28 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023209102A Division JP7823011B2 (ja) | 2015-03-09 | 2023-12-12 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022105084A JP2022105084A (ja) | 2022-07-12 |
| JP2022105084A5 true JP2022105084A5 (https=) | 2022-11-22 |
| JP7403575B2 JP7403575B2 (ja) | 2023-12-22 |
Family
ID=55863122
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017547456A Pending JP2018509413A (ja) | 2015-03-09 | 2016-03-08 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
| JP2021016293A Active JP7050191B2 (ja) | 2015-03-09 | 2021-02-04 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
| JP2022051047A Active JP7391132B2 (ja) | 2015-03-09 | 2022-03-28 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
| JP2022072043A Active JP7403575B2 (ja) | 2015-03-09 | 2022-04-26 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
| JP2023209102A Active JP7823011B2 (ja) | 2015-03-09 | 2023-12-12 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
| JP2025174910A Pending JP2026012786A (ja) | 2015-03-09 | 2025-10-16 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017547456A Pending JP2018509413A (ja) | 2015-03-09 | 2016-03-08 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
| JP2021016293A Active JP7050191B2 (ja) | 2015-03-09 | 2021-02-04 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
| JP2022051047A Active JP7391132B2 (ja) | 2015-03-09 | 2022-03-28 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023209102A Active JP7823011B2 (ja) | 2015-03-09 | 2023-12-12 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
| JP2025174910A Pending JP2026012786A (ja) | 2015-03-09 | 2025-10-16 | FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20160264669A1 (https=) |
| EP (2) | EP3268391B1 (https=) |
| JP (6) | JP2018509413A (https=) |
| KR (1) | KR102720769B1 (https=) |
| AU (2) | AU2016230827B2 (https=) |
| CA (1) | CA2978253A1 (https=) |
| DK (1) | DK3268391T3 (https=) |
| EA (1) | EA038178B1 (https=) |
| ES (1) | ES2882999T3 (https=) |
| HU (1) | HUE056775T2 (https=) |
| IL (2) | IL295425A (https=) |
| LT (1) | LT3268391T (https=) |
| MX (2) | MX386491B (https=) |
| MY (1) | MY188761A (https=) |
| PL (1) | PL3268391T3 (https=) |
| PT (1) | PT3268391T (https=) |
| SG (2) | SG10201908259WA (https=) |
| WO (1) | WO2016142782A1 (https=) |
| ZA (1) | ZA202109042B (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201605203UA (en) | 2013-12-24 | 2016-07-28 | Argen X N V | Fcrn antagonists and methods of use |
| RS64768B1 (sr) * | 2015-01-30 | 2023-11-30 | Momenta Pharmaceuticals Inc | Fcrn antitela i načini njihove upotrebe |
| CA2978253A1 (en) * | 2015-03-09 | 2016-09-15 | Argenx Bvba | Methods of reducing serum levels of fc-containing agents using fcrn antagonists |
| WO2018007999A1 (en) | 2016-07-08 | 2018-01-11 | Staten Biotechnology B.V. | Anti-apoc3 antibodies and methods of use thereof |
| GB201618424D0 (en) * | 2016-11-01 | 2016-12-14 | Argenix Bvba | Treatment of antibody mediated disease |
| CN110506056A (zh) | 2017-04-21 | 2019-11-26 | 斯塔滕生物技术有限公司 | 抗apoc3抗体和其使用方法 |
| PE20210119A1 (es) | 2017-10-31 | 2021-01-19 | Staten Biotechnology B V | Anticuerpos anti-apoc3 y metodos de uso de estos |
| CA3081144A1 (en) * | 2017-12-08 | 2019-06-13 | Argenx Bvba | Use of fcrn antagonists for treatment of generalized myasthenia gravis |
| US12202900B2 (en) | 2018-06-08 | 2025-01-21 | argenx BV | Compositions and methods for treating immune thrombocytopenia |
| WO2020148336A1 (en) * | 2019-01-16 | 2020-07-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of agents capable of inducing lc3-associated phagocytosis for treating sustained inflammation in patients suffering from chronic liver disease |
| GB2589049C (en) * | 2019-04-11 | 2024-02-21 | argenx BV | Anti-IgE antibodies |
| WO2020232247A1 (en) | 2019-05-14 | 2020-11-19 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
| JP7565951B2 (ja) | 2019-06-07 | 2024-10-11 | アルジェニクス ビーブイ | 皮下投与に好適なFcRnインヒビターの医薬製剤 |
| WO2021016571A2 (en) * | 2019-07-25 | 2021-01-28 | Genzyme Corporation | Methods of treating antibody-mediated disorders with fcrn antagonists |
| JP2023509195A (ja) | 2020-01-08 | 2023-03-07 | アルジェニクス ビーブイ | 天疱瘡症を治療する方法 |
| CN114341184B (zh) * | 2020-02-10 | 2023-04-04 | 北京拓界生物医药科技有限公司 | 抗FcRn抗体、其抗原结合片段及其医药用途 |
| IL298999A (en) | 2020-06-11 | 2023-02-01 | Provention Bio Inc | Methods and compositions for the prevention of type 1 diabetes |
| AU2021292200A1 (en) * | 2020-06-17 | 2023-02-02 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of gene therapy patients |
| JP2024520444A (ja) | 2021-05-24 | 2024-05-24 | プロヴェンション・バイオ・インコーポレイテッド | 1型糖尿病を治療するための方法 |
| JP7755725B2 (ja) * | 2021-08-13 | 2025-10-16 | ジャンスー バイオジェッテイ バイオテクノロジー カンパニー リミテッド | Fcrnを特異的に認識する抗体およびその使用 |
| CN119698429A (zh) | 2022-06-15 | 2025-03-25 | 阿根思有限公司 | Fcrn结合分子及使用方法 |
| CN120344557A (zh) * | 2022-11-14 | 2025-07-18 | 阿根思有限公司 | Fcrn拮抗剂分子及其使用方法 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3101690B2 (ja) | 1987-03-18 | 2000-10-23 | エス・ビィ・2・インコーポレイテッド | 変性抗体の、または変性抗体に関する改良 |
| US5677425A (en) | 1987-09-04 | 1997-10-14 | Celltech Therapeutics Limited | Recombinant antibody |
| US5326856A (en) | 1992-04-09 | 1994-07-05 | Cytogen Corporation | Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding |
| CA2118508A1 (en) | 1992-04-24 | 1993-11-11 | Elizabeth S. Ward | Recombinant production of immunoglobulin-like domains in prokaryotic cells |
| US5885573A (en) | 1993-06-01 | 1999-03-23 | Arch Development Corporation | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
| AU691811B2 (en) | 1993-06-16 | 1998-05-28 | Celltech Therapeutics Limited | Antibodies |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| US6121022A (en) | 1995-04-14 | 2000-09-19 | Genentech, Inc. | Altered polypeptides with increased half-life |
| US5869046A (en) | 1995-04-14 | 1999-02-09 | Genentech, Inc. | Altered polypeptides with increased half-life |
| US6128119A (en) | 1997-01-10 | 2000-10-03 | Asahi Kogaku Kogyo Kabushiki Kaisha | Beam shaping optical system |
| US6277375B1 (en) | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| US6528624B1 (en) | 1998-04-02 | 2003-03-04 | Genentech, Inc. | Polypeptide variants |
| US6194551B1 (en) | 1998-04-02 | 2001-02-27 | Genentech, Inc. | Polypeptide variants |
| GB9809951D0 (en) | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
| PL209392B1 (pl) | 1999-01-15 | 2011-08-31 | Genentech Inc | Przeciwciało, komórka gospodarza, sposób wytwarzania przeciwciała oraz zastosowanie przeciwciała |
| US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| HUP0204475A2 (en) | 2000-02-11 | 2003-04-28 | Merck Patent Gmbh | Enhancing the circulating half-life of antibody-based fusion proteins |
| US6725230B2 (en) | 2000-07-18 | 2004-04-20 | Aegis Analytical Corporation | System, method and computer program for assembling process data of multi-database origins using a hierarchical display |
| US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
| WO2002043658A2 (en) | 2000-11-06 | 2002-06-06 | The Jackson Laboratory | Fcrn-based therapeutics for the treatment of auto-immune disorders |
| WO2002040047A2 (en) | 2000-11-20 | 2002-05-23 | Canadian Blood Services | Method for treating thrombocytopenia with monoclonal ivig |
| US7083784B2 (en) | 2000-12-12 | 2006-08-01 | Medimmune, Inc. | Molecules with extended half-lives, compositions and uses thereof |
| NZ571596A (en) | 2001-08-03 | 2010-11-26 | Glycart Biotechnology Ag | Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity |
| US20040002587A1 (en) | 2002-02-20 | 2004-01-01 | Watkins Jeffry D. | Fc region variants |
| US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
| ATE483472T1 (de) | 2002-05-30 | 2010-10-15 | Macrogenics Inc | Cd16a bindungsproteine und verwendung zur behandlung von immunkrankheiten |
| DK1534335T4 (en) | 2002-08-14 | 2015-10-05 | Macrogenics Inc | FCGAMMARIIB-SPECIFIC ANTIBODIES AND PROCEDURES FOR USE THEREOF |
| EP1553975B8 (en) | 2002-09-27 | 2023-04-12 | Xencor, Inc. | Optimized fc variants and methods for their generation |
| DK1562972T3 (da) | 2002-10-15 | 2010-12-06 | Facet Biotech Corp | Modifikation af FcRn-bindingsaffiniteter eller serumhalveringstider for antistoffer ved mutagenese |
| CA2512729C (en) | 2003-01-09 | 2014-09-16 | Macrogenics, Inc. | Identification and engineering of antibodies with variant fc regions and methods of using same |
| CA2512974A1 (en) | 2003-01-13 | 2004-07-29 | Macrogenics, Inc. | Soluble fc.gamma.r fusion proteins and methods of use thereof |
| GB0324368D0 (en) | 2003-10-17 | 2003-11-19 | Univ Cambridge Tech | Polypeptides including modified constant regions |
| WO2006130834A2 (en) * | 2005-05-31 | 2006-12-07 | Board Of Regents, The University Of Texas System | IGGl ANTIBODIES WITH MUTATED FC PORTION FOR INCREASED BINDING TO FCRN RECEPTOR AND USES THEREOF |
| TW200745163A (en) | 2006-02-17 | 2007-12-16 | Syntonix Pharmaceuticals Inc | Peptides that block the binding of IgG to FcRn |
| EP2144930A1 (en) | 2007-04-18 | 2010-01-20 | ZymoGenetics, Inc. | Single chain fc, methods of making and methods of treatment |
| EP2158318A2 (en) | 2007-05-14 | 2010-03-03 | Biogen Idec MA, Inc. | Single-chain fc (scfc) regions, binding polypeptides comprising same, and methods related thereto |
| NZ594343A (en) | 2009-03-25 | 2013-10-25 | Genentech Inc | Novel anti-alpha5beta1 antibodies and uses thereof |
| ES2765874T3 (es) | 2011-05-25 | 2020-06-11 | Innate Pharma Sa | Anticuerpos anti-KIR para el tratamiento de trastornos inflamatorios |
| AU2012328819B2 (en) * | 2011-10-26 | 2017-08-03 | Elanco Tiergesundheit Ag | Monoclonal antibodies and methods of use |
| US20140302028A1 (en) * | 2011-11-18 | 2014-10-09 | Merck Sharp & Dohme Corp. | Fc containing polypeptides having increased anti-inflammatory properties and increased fcrn binding |
| JP6285923B2 (ja) | 2012-06-22 | 2018-02-28 | トラスティーズ・オブ・ダートマス・カレッジ | 新規VISTA−Igコンストラクト及び自己免疫、アレルギー性及び炎症性障害の処置のためのVISTA−Igの使用 |
| SG11201605203UA (en) * | 2013-12-24 | 2016-07-28 | Argen X N V | Fcrn antagonists and methods of use |
| CA2978253A1 (en) * | 2015-03-09 | 2016-09-15 | Argenx Bvba | Methods of reducing serum levels of fc-containing agents using fcrn antagonists |
-
2016
- 2016-03-08 CA CA2978253A patent/CA2978253A1/en active Pending
- 2016-03-08 MY MYPI2017001178A patent/MY188761A/en unknown
- 2016-03-08 EP EP16719896.9A patent/EP3268391B1/en active Active
- 2016-03-08 SG SG10201908259W patent/SG10201908259WA/en unknown
- 2016-03-08 SG SG11201707053SA patent/SG11201707053SA/en unknown
- 2016-03-08 EA EA201791984A patent/EA038178B1/ru unknown
- 2016-03-08 LT LTEPPCT/IB2016/000398T patent/LT3268391T/lt unknown
- 2016-03-08 AU AU2016230827A patent/AU2016230827B2/en active Active
- 2016-03-08 IL IL295425A patent/IL295425A/en unknown
- 2016-03-08 JP JP2017547456A patent/JP2018509413A/ja active Pending
- 2016-03-08 EP EP21189336.7A patent/EP4006051A1/en active Pending
- 2016-03-08 KR KR1020177027256A patent/KR102720769B1/ko active Active
- 2016-03-08 PL PL16719896T patent/PL3268391T3/pl unknown
- 2016-03-08 WO PCT/IB2016/000398 patent/WO2016142782A1/en not_active Ceased
- 2016-03-08 IL IL254403A patent/IL254403B/en unknown
- 2016-03-08 MX MX2017011534A patent/MX386491B/es unknown
- 2016-03-08 ES ES16719896T patent/ES2882999T3/es active Active
- 2016-03-08 US US15/064,195 patent/US20160264669A1/en active Pending
- 2016-03-08 DK DK16719896.9T patent/DK3268391T3/da active
- 2016-03-08 PT PT167198969T patent/PT3268391T/pt unknown
- 2016-03-08 HU HUE16719896A patent/HUE056775T2/hu unknown
-
2017
- 2017-09-08 MX MX2021011633A patent/MX2021011633A/es unknown
-
2021
- 2021-02-04 JP JP2021016293A patent/JP7050191B2/ja active Active
- 2021-11-15 ZA ZA2021/09042A patent/ZA202109042B/en unknown
- 2021-12-02 AU AU2021277720A patent/AU2021277720B2/en active Active
-
2022
- 2022-03-28 JP JP2022051047A patent/JP7391132B2/ja active Active
- 2022-04-26 JP JP2022072043A patent/JP7403575B2/ja active Active
-
2023
- 2023-12-12 JP JP2023209102A patent/JP7823011B2/ja active Active
-
2025
- 2025-10-16 JP JP2025174910A patent/JP2026012786A/ja active Pending
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