JP2022105084A5 - - Google Patents

Download PDF

Info

Publication number
JP2022105084A5
JP2022105084A5 JP2022072043A JP2022072043A JP2022105084A5 JP 2022105084 A5 JP2022105084 A5 JP 2022105084A5 JP 2022072043 A JP2022072043 A JP 2022072043A JP 2022072043 A JP2022072043 A JP 2022072043A JP 2022105084 A5 JP2022105084 A5 JP 2022105084A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
disease
acid sequence
amino acid
autoimmune
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022072043A
Other languages
English (en)
Japanese (ja)
Other versions
JP7403575B2 (ja
JP2022105084A (ja
Filing date
Publication date
Priority claimed from JP2022051047A external-priority patent/JP7391132B2/ja
Application filed filed Critical
Publication of JP2022105084A publication Critical patent/JP2022105084A/ja
Publication of JP2022105084A5 publication Critical patent/JP2022105084A5/ja
Priority to JP2023209102A priority Critical patent/JP7823011B2/ja
Application granted granted Critical
Publication of JP7403575B2 publication Critical patent/JP7403575B2/ja
Priority to JP2025174910A priority patent/JP2026012786A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022072043A 2015-03-09 2022-04-26 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法 Active JP7403575B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023209102A JP7823011B2 (ja) 2015-03-09 2023-12-12 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法
JP2025174910A JP2026012786A (ja) 2015-03-09 2025-10-16 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562130076P 2015-03-09 2015-03-09
US62/130,076 2015-03-09
JP2022051047A JP7391132B2 (ja) 2015-03-09 2022-03-28 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2022051047A Division JP7391132B2 (ja) 2015-03-09 2022-03-28 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023209102A Division JP7823011B2 (ja) 2015-03-09 2023-12-12 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法

Publications (3)

Publication Number Publication Date
JP2022105084A JP2022105084A (ja) 2022-07-12
JP2022105084A5 true JP2022105084A5 (enExample) 2022-11-22
JP7403575B2 JP7403575B2 (ja) 2023-12-22

Family

ID=55863122

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2017547456A Pending JP2018509413A (ja) 2015-03-09 2016-03-08 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法
JP2021016293A Active JP7050191B2 (ja) 2015-03-09 2021-02-04 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法
JP2022051047A Active JP7391132B2 (ja) 2015-03-09 2022-03-28 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法
JP2022072043A Active JP7403575B2 (ja) 2015-03-09 2022-04-26 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法
JP2023209102A Active JP7823011B2 (ja) 2015-03-09 2023-12-12 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法
JP2025174910A Pending JP2026012786A (ja) 2015-03-09 2025-10-16 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP2017547456A Pending JP2018509413A (ja) 2015-03-09 2016-03-08 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法
JP2021016293A Active JP7050191B2 (ja) 2015-03-09 2021-02-04 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法
JP2022051047A Active JP7391132B2 (ja) 2015-03-09 2022-03-28 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023209102A Active JP7823011B2 (ja) 2015-03-09 2023-12-12 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法
JP2025174910A Pending JP2026012786A (ja) 2015-03-09 2025-10-16 FcRnアンタゴニストを用いてFc含有剤の血清レベルを低下させる方法

Country Status (19)

Country Link
US (1) US20160264669A1 (enExample)
EP (2) EP4006051A1 (enExample)
JP (6) JP2018509413A (enExample)
KR (1) KR102720769B1 (enExample)
AU (2) AU2016230827B2 (enExample)
CA (1) CA2978253A1 (enExample)
DK (1) DK3268391T3 (enExample)
EA (1) EA038178B1 (enExample)
ES (1) ES2882999T3 (enExample)
HU (1) HUE056775T2 (enExample)
IL (2) IL254403B (enExample)
LT (1) LT3268391T (enExample)
MX (2) MX386491B (enExample)
MY (1) MY188761A (enExample)
PL (1) PL3268391T3 (enExample)
PT (1) PT3268391T (enExample)
SG (2) SG10201908259WA (enExample)
WO (1) WO2016142782A1 (enExample)
ZA (1) ZA202109042B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106103476B (zh) 2013-12-24 2020-11-27 阿尔金克斯有限公司 FcRn拮抗剂及使用方法
JP6853178B2 (ja) * 2015-01-30 2021-03-31 モメンタ ファーマシューティカルズ インコーポレイテッド FcRn抗体およびその使用方法
MX386491B (es) * 2015-03-09 2025-03-18 argenx BV Metodos para reducir los niveles de suero de agentes que contienen fc que usan antagonistas de fcrn.
WO2018007999A1 (en) 2016-07-08 2018-01-11 Staten Biotechnology B.V. Anti-apoc3 antibodies and methods of use thereof
GB201618424D0 (en) * 2016-11-01 2016-12-14 Argenix Bvba Treatment of antibody mediated disease
WO2018193427A1 (en) 2017-04-21 2018-10-25 Staten Biotechnology B.V. Anti-apoc3 antibodies and methods of use thereof
CN111315772A (zh) 2017-10-31 2020-06-19 斯塔顿生物技术有限公司 抗apoc3抗体及其使用方法
MA51032A (fr) * 2017-12-08 2021-03-17 Argenx Bvba Utilisation d'antagonistes de fcrn pour le traitement de la myasthénie grave généralisée
JP7486437B2 (ja) 2018-06-08 2024-05-17 アルジェニクス ビーブイ 免疫性血小板減少症を治療する組成物及び方法
WO2020148336A1 (en) * 2019-01-16 2020-07-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of agents capable of inducing lc3-associated phagocytosis for treating sustained inflammation in patients suffering from chronic liver disease
GB2589049C (en) * 2019-04-11 2024-02-21 argenx BV Anti-IgE antibodies
JP7137696B2 (ja) 2019-05-14 2022-09-14 プロヴェンション・バイオ・インコーポレイテッド 1型糖尿病を予防するための方法および組成物
BR112021024632A2 (pt) * 2019-06-07 2022-01-18 Argenx Bvba Formulações farmacêuticas de inibidores de fcrn adequados para administração subcutânea
CN114466663B (zh) * 2019-07-25 2026-01-02 建新公司 以FcRn拮抗剂治疗抗体介导的障碍的方法
ES2992247T3 (es) 2020-01-08 2024-12-11 argenx BV Antagonistas del receptor de Fc neonatal humano (FcRn) para el tratamiento de trastornos del pénfigo
WO2021160116A1 (zh) * 2020-02-10 2021-08-19 北京拓界生物医药科技有限公司 抗FcRn抗体、其抗原结合片段及其医药用途
KR20230092863A (ko) 2020-06-11 2023-06-26 프로벤션 바이오, 인코포레이티드 제1형 당뇨병을 예방하기 위한 방법 및 조성물
CA3183153A1 (en) * 2020-06-17 2021-12-23 Christian HINDERER Compositions and methods for treatment of gene therapy patients
MX2023013851A (es) 2021-05-24 2023-12-08 Provention Bio Inc Metodos para el tratamiento de diabetes tipo 1.
CN117693523A (zh) * 2021-08-13 2024-03-12 舒泰神(北京)生物制药股份有限公司 特异性识别fcrn的抗体及其用途
KR20250037789A (ko) 2022-06-15 2025-03-18 아르젠엑스 비브이 Fcrn/항원-결합 분자 및 사용 방법
IL320846A (en) * 2022-11-14 2025-07-01 argenx BV Fcrn antagonist molecules and methods of use thereof

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3101690B2 (ja) 1987-03-18 2000-10-23 エス・ビィ・2・インコーポレイテッド 変性抗体の、または変性抗体に関する改良
US5677425A (en) 1987-09-04 1997-10-14 Celltech Therapeutics Limited Recombinant antibody
US5326856A (en) 1992-04-09 1994-07-05 Cytogen Corporation Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding
AU4116793A (en) 1992-04-24 1993-11-29 Board Of Regents, The University Of Texas System Recombinant production of immunoglobulin-like domains in prokaryotic cells
US5885573A (en) 1993-06-01 1999-03-23 Arch Development Corporation Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies
AU691811B2 (en) 1993-06-16 1998-05-28 Celltech Therapeutics Limited Antibodies
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US5869046A (en) 1995-04-14 1999-02-09 Genentech, Inc. Altered polypeptides with increased half-life
US6121022A (en) 1995-04-14 2000-09-19 Genentech, Inc. Altered polypeptides with increased half-life
US6128119A (en) 1997-01-10 2000-10-03 Asahi Kogaku Kogyo Kabushiki Kaisha Beam shaping optical system
US6277375B1 (en) 1997-03-03 2001-08-21 Board Of Regents, The University Of Texas System Immunoglobulin-like domains with increased half-lives
US6194551B1 (en) 1998-04-02 2001-02-27 Genentech, Inc. Polypeptide variants
US6528624B1 (en) 1998-04-02 2003-03-04 Genentech, Inc. Polypeptide variants
GB9809951D0 (en) 1998-05-08 1998-07-08 Univ Cambridge Tech Binding molecules
HUP0104865A3 (en) 1999-01-15 2004-07-28 Genentech Inc Polypeptide variants with altered effector function
US6737056B1 (en) * 1999-01-15 2004-05-18 Genentech, Inc. Polypeptide variants with altered effector function
JP5179689B2 (ja) 2000-02-11 2013-04-10 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 抗体ベース融合タンパク質の循環系内半減期の増強
US6725230B2 (en) 2000-07-18 2004-04-20 Aegis Analytical Corporation System, method and computer program for assembling process data of multi-database origins using a hierarchical display
US6946292B2 (en) 2000-10-06 2005-09-20 Kyowa Hakko Kogyo Co., Ltd. Cells producing antibody compositions with increased antibody dependent cytotoxic activity
WO2002043658A2 (en) 2000-11-06 2002-06-06 The Jackson Laboratory Fcrn-based therapeutics for the treatment of auto-immune disorders
EP1370288B1 (en) 2000-11-20 2012-01-11 Canadian Blood Services Method for treating thrombocytopenia with monoclonal ivig
EP1355919B1 (en) 2000-12-12 2010-11-24 MedImmune, LLC Molecules with extended half-lives, compositions and uses thereof
EP1423510A4 (en) 2001-08-03 2005-06-01 Glycart Biotechnology Ag ANTIBODY GLYCOSYLATION VARIANTS WITH INCREASED ANTIBODY-DEPENDENT CELLULAR CYTOTOXICITY
US20040002587A1 (en) 2002-02-20 2004-01-01 Watkins Jeffry D. Fc region variants
US20040132101A1 (en) 2002-09-27 2004-07-08 Xencor Optimized Fc variants and methods for their generation
CA2487932A1 (en) 2002-05-30 2003-12-11 Macrogenics, Inc. Cd16a binding proteins and use for the treatment of immune disorders
PT1534335E (pt) 2002-08-14 2012-02-28 Macrogenics Inc Anticorpos específicos de fcγriib e processos para a sua utilização
CA2832136C (en) 2002-09-27 2015-11-17 Xencor Optimized fc variants and methods for their generation
ATE480562T1 (de) 2002-10-15 2010-09-15 Facet Biotech Corp Veränderung von fcrn-bindungsaffinitäten oder von serumhalbwertszeiten von antikörpern mittels mutagenese
US7355008B2 (en) 2003-01-09 2008-04-08 Macrogenics, Inc. Identification and engineering of antibodies with variant Fc regions and methods of using same
AU2004204817C1 (en) 2003-01-13 2011-01-20 Macrogenics, Inc. Soluble FcyR fusion proteins and methods of use thereof
GB0324368D0 (en) 2003-10-17 2003-11-19 Univ Cambridge Tech Polypeptides including modified constant regions
WO2006130834A2 (en) * 2005-05-31 2006-12-07 Board Of Regents, The University Of Texas System IGGl ANTIBODIES WITH MUTATED FC PORTION FOR INCREASED BINDING TO FCRN RECEPTOR AND USES THEREOF
TW200745163A (en) 2006-02-17 2007-12-16 Syntonix Pharmaceuticals Inc Peptides that block the binding of IgG to FcRn
CA2682605A1 (en) 2007-04-18 2008-10-30 Zymogenetics, Inc. Single chain fc, methods of making and methods of treatment
MX2009012343A (es) 2007-05-14 2010-02-10 Biogen Idec Inc Regiones fc (sc fc) de cadena sencilla, polipeptidos de enlace que comprenden las mismas, y metodos relacionados con ello.
CN103755808B (zh) * 2009-03-25 2016-02-10 霍夫曼-拉罗奇有限公司 抗-α5β1抗体及其应用
US9067997B2 (en) * 2011-05-25 2015-06-30 Innate Pharma Sa Anti-KIR antibodies for the treatment of inflammatory and autoimmune disorders
US9790280B2 (en) * 2011-10-26 2017-10-17 Elanco Tiergesundheit Ag Monoclonal canine CD20 antibodies and methods of use
EP2780463A4 (en) * 2011-11-18 2015-07-01 Merck Sharp & Dohme FC-CONTAINING POLYPEPTIDES WITH INCREASED INFLAMMATORY FEATURES AND INCREASED FCRN BINDING
CN104619722B (zh) * 2012-06-22 2022-10-04 达特茅斯大学理事会 新型vista-ig构建体和vista-ig用于治疗自身免疫性、过敏性和炎性疾病的用途
CN106103476B (zh) * 2013-12-24 2020-11-27 阿尔金克斯有限公司 FcRn拮抗剂及使用方法
MX386491B (es) * 2015-03-09 2025-03-18 argenx BV Metodos para reducir los niveles de suero de agentes que contienen fc que usan antagonistas de fcrn.

Similar Documents

Publication Publication Date Title
JP2017501725A5 (enExample)
JP2018509413A5 (enExample)
JP2025504815A5 (enExample)
JP2025520420A5 (enExample)
ES2823950T3 (es) Moléculas con especificidad para CD45 y CD79
CA3258002A1 (en) FCRN BINDING MOLECULES AND METHODS OF USE
RU2005134394A (ru) Лечение аутоиммунных заболеваний у пациента с неадекватным ответом на ингибитор tnf-альфа
JP2016527187A5 (enExample)
CA3034480A1 (en) Antibodies against signal-regulatory protein alpha and methods of use
US20080227704A1 (en) CXCL13 binding proteins
JP2014520092A5 (enExample)
JP2018522578A (ja) ヒト化型親和性成熟抗FcRn抗体
JPH1087510A (ja) ナイトロジェンマスタード系抗癌剤と組合わせて使用するための骨髄腫治療剤
JP2024530152A5 (enExample)
JP2018524007A (ja) Cd22に結合する抗体分子
JP2012503977A (ja) ヒトil17に対する抗体およびその使用
JP2018529313A (ja) Cd79に結合する抗体分子
WO2010055366A4 (en) Anti-human il-21 monoclonal antibodies
JP7688805B2 (ja) 二重特異性抗体
JP2022521850A5 (enExample)
HK1207870A1 (en) Anti-human sema4a antibodies useful to treat disease
JPWO2020004490A5 (enExample)
WO2020091634A1 (ru) Моноклональное антитело, которое специфически связывается с cd20
JP2025507836A (ja) 骨髄コンディショニング方法
US20250313644A1 (en) Antibodies capable of specifically binding tl1a and use thereof