JP2017501725A5 - - Google Patents
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- JP2017501725A5 JP2017501725A5 JP2016542697A JP2016542697A JP2017501725A5 JP 2017501725 A5 JP2017501725 A5 JP 2017501725A5 JP 2016542697 A JP2016542697 A JP 2016542697A JP 2016542697 A JP2016542697 A JP 2016542697A JP 2017501725 A5 JP2017501725 A5 JP 2017501725A5
- Authority
- JP
- Japan
- Prior art keywords
- fcrn antagonist
- region
- pharmaceutical composition
- fcrn
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361920547P | 2013-12-24 | 2013-12-24 | |
| US61/920,547 | 2013-12-24 | ||
| PCT/US2014/072087 WO2015100299A1 (en) | 2013-12-24 | 2014-12-23 | Fcrn antagonists and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019002272A Division JP2019076103A (ja) | 2013-12-24 | 2019-01-10 | ＦｃＲｎアンタゴニスト及び使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017501725A JP2017501725A (ja) | 2017-01-19 |
| JP2017501725A5 true JP2017501725A5 (enExample) | 2017-12-14 |
| JP6554473B2 JP6554473B2 (ja) | 2019-07-31 |
Family
ID=52347464
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016542697A Active JP6554473B2 (ja) | 2013-12-24 | 2014-12-23 | ＦｃＲｎアンタゴニスト及び使用方法 |
| JP2019002272A Pending JP2019076103A (ja) | 2013-12-24 | 2019-01-10 | ＦｃＲｎアンタゴニスト及び使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019002272A Pending JP2019076103A (ja) | 2013-12-24 | 2019-01-10 | ＦｃＲｎアンタゴニスト及び使用方法 |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US10316073B2 (enExample) |
| EP (2) | EP3626738A1 (enExample) |
| JP (2) | JP6554473B2 (enExample) |
| KR (3) | KR20240033084A (enExample) |
| CN (2) | CN106103476B (enExample) |
| AU (1) | AU2014369999B2 (enExample) |
| BR (1) | BR112016014810B1 (enExample) |
| CA (1) | CA2934644C (enExample) |
| DK (1) | DK3087095T3 (enExample) |
| EA (1) | EA035324B1 (enExample) |
| ES (1) | ES2742682T3 (enExample) |
| FI (1) | FIC20230003I1 (enExample) |
| FR (1) | FR23C1004I2 (enExample) |
| HU (2) | HUE046822T2 (enExample) |
| IL (1) | IL246223B (enExample) |
| LT (2) | LT3087095T (enExample) |
| LU (1) | LUC00284I2 (enExample) |
| MX (1) | MX368804B (enExample) |
| NL (1) | NL301203I2 (enExample) |
| NO (1) | NO2022049I1 (enExample) |
| NZ (1) | NZ722055A (enExample) |
| PL (1) | PL3087095T3 (enExample) |
| PT (1) | PT3087095T (enExample) |
| SG (2) | SG11201605203UA (enExample) |
| WO (1) | WO2015100299A1 (enExample) |
| ZA (2) | ZA201604464B (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106103476B (zh) | 2013-12-24 | 2020-11-27 | 阿尔金克斯有限公司 | FcRn拮抗剂及使用方法 |
| MX386491B (es) * | 2015-03-09 | 2025-03-18 | argenx BV | Metodos para reducir los niveles de suero de agentes que contienen fc que usan antagonistas de fcrn. |
| FR3038517B1 (fr) * | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
| CN106957365B (zh) * | 2016-01-11 | 2021-03-16 | 上海交通大学 | 一种单克隆抗体FnAb8及其应用 |
| CN106957364B (zh) * | 2016-01-11 | 2021-03-16 | 上海交通大学 | 一种单克隆抗体FnAb12及其应用 |
| EP3257866A1 (en) * | 2016-06-17 | 2017-12-20 | Academisch Medisch Centrum | Modified anti-tnf antibody and use thereof in the treatment of ibd |
| WO2018007999A1 (en) | 2016-07-08 | 2018-01-11 | Staten Biotechnology B.V. | Anti-apoc3 antibodies and methods of use thereof |
| BR112019001806A2 (pt) | 2016-07-29 | 2019-05-07 | Momenta Pharmaceuticals, Inc. | anticorpos para fcrn e métodos de uso dos mesmos |
| GB201618424D0 (en) * | 2016-11-01 | 2016-12-14 | Argenix Bvba | Treatment of antibody mediated disease |
| WO2018102668A1 (en) * | 2016-12-02 | 2018-06-07 | The Texas A&M University System | Fusion proteins for selectively depleting antigen-specific antibodies |
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| CN111315772A (zh) | 2017-10-31 | 2020-06-19 | 斯塔顿生物技术有限公司 | 抗apoc3抗体及其使用方法 |
| MA51032A (fr) | 2017-12-08 | 2021-03-17 | Argenx Bvba | Utilisation d'antagonistes de fcrn pour le traitement de la myasthénie grave généralisée |
| JP7486437B2 (ja) * | 2018-06-08 | 2024-05-17 | アルジェニクス ビーブイ | 免疫性血小板減少症を治療する組成物及び方法 |
| EA202190264A1 (ru) | 2018-07-20 | 2021-05-20 | Момента Фармасьютикалз, Инк. | КОМПОЗИЦИИ АНТИТЕЛ ПРОТИВ FcRn |
| WO2020054979A1 (ko) * | 2018-09-12 | 2020-03-19 | 아주대학교산학협력단 | Cd83 억제제를 유효성분으로 포함하는 베체트병의 예방 또는 치료용 조성물 |
| GB2589049C (en) * | 2019-04-11 | 2024-02-21 | argenx BV | Anti-IgE antibodies |
| JP7137696B2 (ja) | 2019-05-14 | 2022-09-14 | プロヴェンション・バイオ・インコーポレイテッド | １型糖尿病を予防するための方法および組成物 |
| BR112021024632A2 (pt) * | 2019-06-07 | 2022-01-18 | Argenx Bvba | Formulações farmacêuticas de inibidores de fcrn adequados para administração subcutânea |
| CN114466663B (zh) | 2019-07-25 | 2026-01-02 | 建新公司 | 以FcRn拮抗剂治疗抗体介导的障碍的方法 |
| ES2992247T3 (es) | 2020-01-08 | 2024-12-11 | argenx BV | Antagonistas del receptor de Fc neonatal humano (FcRn) para el tratamiento de trastornos del pénfigo |
| WO2021160116A1 (zh) * | 2020-02-10 | 2021-08-19 | 北京拓界生物医药科技有限公司 | 抗FcRn抗体、其抗原结合片段及其医药用途 |
| CA3181572A1 (en) * | 2020-06-08 | 2021-12-16 | Paul STABACH | Compositions and methods for treating and/or preventing coagulopathy and/or sepsis in patients suffering from bacterial and/or viral infections |
| CN113769058B (zh) * | 2020-06-10 | 2024-09-06 | 上海宝济药业股份有限公司 | 一种药物组合及其应用 |
| KR20230092863A (ko) | 2020-06-11 | 2023-06-26 | 프로벤션 바이오, 인코포레이티드 | 제1형 당뇨병을 예방하기 위한 방법 및 조성물 |
| MX2023013851A (es) | 2021-05-24 | 2023-12-08 | Provention Bio Inc | Metodos para el tratamiento de diabetes tipo 1. |
| US20240309065A1 (en) | 2021-06-23 | 2024-09-19 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Short apoc-ii mimetic peptides and methods of use |
| IL314367A (en) | 2022-01-18 | 2024-09-01 | argenx BV | Antibodies to galectin 10 |
| KR20240151809A (ko) | 2022-02-21 | 2024-10-18 | 아르젠엑스 비브이 | Fcrn 길항제를 사용하여 근염을 치료하는 방법 |
| CN119013290A (zh) | 2022-04-13 | 2024-11-22 | Ose免疫疗法公司 | 用于选择性清除抗体的新型分子 |
| CN119233984A (zh) | 2022-05-05 | 2024-12-31 | 美国政府(由卫生和人类服务部的部长所代表) | 短载脂蛋白e模拟肽及其使用方法 |
| KR20250037789A (ko) | 2022-06-15 | 2025-03-18 | 아르젠엑스 비브이 | Fcrn/항원-결합 분자 및 사용 방법 |
| CN115645537A (zh) * | 2022-10-25 | 2023-01-31 | 成都臻拓医药科技有限公司 | FcRn抑制剂在制备抑制自身免疫性疾病复发的药物中的用途 |
| IL320846A (en) * | 2022-11-14 | 2025-07-01 | argenx BV | Fcrn antagonist molecules and methods of use thereof |
| EP4658368A1 (en) | 2023-02-04 | 2025-12-10 | Momenta Pharmaceuticals, Inc. | Compositions and methods for treating hemolytic disease of the fetus and newborn |
| IL322519A (en) | 2023-02-17 | 2025-10-01 | Ablynx Nv | Polypeptides that bind to the neonatal fc receptor |
| CN120882427A (zh) * | 2023-03-24 | 2025-10-31 | 派拉冈医疗公司 | 结合FcRn的Fc片段和使用方法 |
| US20250034260A1 (en) | 2023-07-05 | 2025-01-30 | Sanofi | Fcrn antagonists for treatment of igg-related diseases and disorders |
| IL325970A (en) | 2023-07-16 | 2026-03-01 | argenx BV | Methods for treating chronic inflammatory demyelinating polyneuropathy |
| TW202527982A (zh) | 2023-09-11 | 2025-07-16 | 美商默門塔醫藥公司 | Fcrn抗體之醫藥組成物 |
| IL328082A (en) | 2023-11-06 | 2026-06-01 | Momenta Pharmaceuticals Inc | Compositions and methods for treating rheumatoid arthritis |
| GB202319605D0 (en) | 2023-12-20 | 2024-01-31 | argenx BV | Monovalent binding molecules and methods of use |
| WO2025163617A1 (en) | 2024-02-04 | 2025-08-07 | Momenta Pharmaceuticals, Inc. | Compositions and methods for treating sjögren's disease |
| WO2025186787A1 (en) | 2024-03-08 | 2025-09-12 | Momenta Pharmaceuticals, Inc. | Compositions and methods for treating fetal and neonatal alloimmune thrombocytopenia |
| WO2025229206A1 (en) | 2024-05-03 | 2025-11-06 | argenx BV | Monovalent anti-iga binding molecules and methods of use |
| WO2025233685A1 (en) | 2024-05-10 | 2025-11-13 | argenx BV | Intravenous fcrn antagonist formulations and methods of use thereof |
| TW202608428A (zh) | 2024-05-10 | 2026-03-01 | 比利時商阿根思公司 | 皮下調配物、預填充注射器及其使用方法 |
| WO2026083290A1 (en) | 2024-10-16 | 2026-04-23 | Momenta Pharmaceuticals, Inc. | Compositions and methods for treating sjögren's disease |
| CN119490588B (zh) * | 2024-10-17 | 2026-03-06 | 广州康盛生物科技股份有限公司 | 一种抗人FcRn的VHH抗体及其应用 |
| CN120966834A (zh) * | 2025-09-01 | 2025-11-18 | 上海市东方医院（同济大学附属东方医院） | 一种靶向FcRn和FcγRs的双特异性纳米抗体及其制备方法和用途 |
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| MA51032A (fr) | 2017-12-08 | 2021-03-17 | Argenx Bvba | Utilisation d'antagonistes de fcrn pour le traitement de la myasthénie grave généralisée |
| JP7486437B2 (ja) | 2018-06-08 | 2024-05-17 | アルジェニクス ビーブイ | 免疫性血小板減少症を治療する組成物及び方法 |
| EP3969125A4 (en) | 2019-05-17 | 2023-01-11 | Alexion Pharmaceuticals, Inc. | USE OF ANTI-FCRN ANTIBODIES IN THE TREATMENT OF PEMPHIGHUS AND PEMPHIGOID DISEASES |
| BR112021024632A2 (pt) * | 2019-06-07 | 2022-01-18 | Argenx Bvba | Formulações farmacêuticas de inibidores de fcrn adequados para administração subcutânea |
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