JP2022028930A - 湾曲骨接触要素を備えるインプラント - Google Patents
湾曲骨接触要素を備えるインプラント Download PDFInfo
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- JP2022028930A JP2022028930A JP2021197842A JP2021197842A JP2022028930A JP 2022028930 A JP2022028930 A JP 2022028930A JP 2021197842 A JP2021197842 A JP 2021197842A JP 2021197842 A JP2021197842 A JP 2021197842A JP 2022028930 A JP2022028930 A JP 2022028930A
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- Prior art keywords
- implant
- bone contact
- contact element
- arched
- support beam
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B22—CASTING; POWDER METALLURGY
- B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
- B22F10/00—Additive manufacturing of workpieces or articles from metallic powder
- B22F10/20—Direct sintering or melting
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B22—CASTING; POWDER METALLURGY
- B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
- B22F3/00—Manufacture of workpieces or articles from metallic powder characterised by the manner of compacting or sintering; Apparatus specially adapted therefor ; Presses and furnaces
- B22F3/10—Sintering only
- B22F3/11—Making porous workpieces or articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B22—CASTING; POWDER METALLURGY
- B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
- B22F3/00—Manufacture of workpieces or articles from metallic powder characterised by the manner of compacting or sintering; Apparatus specially adapted therefor ; Presses and furnaces
- B22F3/22—Manufacture of workpieces or articles from metallic powder characterised by the manner of compacting or sintering; Apparatus specially adapted therefor ; Presses and furnaces for producing castings from a slip
- B22F3/225—Manufacture of workpieces or articles from metallic powder characterised by the manner of compacting or sintering; Apparatus specially adapted therefor ; Presses and furnaces for producing castings from a slip by injection molding
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B22—CASTING; POWDER METALLURGY
- B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
- B22F3/00—Manufacture of workpieces or articles from metallic powder characterised by the manner of compacting or sintering; Apparatus specially adapted therefor ; Presses and furnaces
- B22F3/22—Manufacture of workpieces or articles from metallic powder characterised by the manner of compacting or sintering; Apparatus specially adapted therefor ; Presses and furnaces for producing castings from a slip
- B22F3/227—Manufacture of workpieces or articles from metallic powder characterised by the manner of compacting or sintering; Apparatus specially adapted therefor ; Presses and furnaces for producing castings from a slip by organic binder assisted extrusion
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P10/00—Technologies related to metal processing
- Y02P10/25—Process efficiency
Abstract
Description
形成する実質的に滑らかな表面を含む。後縁部は、挿入ツールを受容するように構成された少なくとも1つのレセプタクルを含むモノリシック構造を含む。また、インプラントはさらに、前縁部と後縁部との間に延びているインプラントの周辺部分を形成する少なくとも1つの実質的に渦巻状の細長い部材を含む。
るインプラント)」と題された、2018年9月13日公開の米国公開第2018/0256351号に開示された本体部/支持構造、要素、フレーム、プレートまたは他の構造のうちの任意のものを利用してもよい。
図1~図3は、インプラント100の実施形態を示す等角図である。インプラント100はまた、ケージまたは固定デバイスと称されてもよい。いくつかの実施形態では、インプラント100は、人体の一部内に埋め込まれるように構成されている。いくつかの実施形態では、インプラント100は、脊椎への埋め込みのために構成されていてもよい。いくつかの実施形態において、インプラント100は、椎骨間に支持を提供するために、および/または、椎骨間の癒合(fusion)を容易にするために隣接する椎骨の間に挿入される、脊椎固定インプラントまたは脊椎固定デバイスであってもよい。
104も含んでもよい。複数のアーチ状骨接触要素104は、本体部102に取り付けられていても、および/または本体部102と連続的に形成(または「一体的に形成」)されていてもよい。
いくつかの実施形態では、本体部は、周辺構造と周辺構造から延びている1つ以上の支持ビームとを含んでもよい。周辺構造は、任意の数のプレート、壁または同様の構造で構
成されていてもよい。いくつかの実施形態では、周辺構造はリングを含むことができるであろう。換言すれば、いくつかの実施形態では、周辺構造は、周辺リング構造とすることができるであろう。図1~図3に見られるように、本体部102はさらに、周辺構造150からなっていてもよい。周辺構造150は、リング状幾何学形状を有するように示されている。
いくつかの実施形態では、本体部は、周辺構造を補強するために作用する1つ以上の支持ビーム(または支持構造)を備えてもよい。いくつかの実施形態では、1つ以上の支持ビームは、周辺構造の内部に沿って配置することができるであろう。たとえば、いくつかの実施形態において、1つ以上の支持ビームは、内側に面する支持構造の表面上の第1位置から、内側(または近位)に面する支持構造の表面上の第2位置へと延びることができるであろう。換言すれば、いくつかの実施形態では、1つ以上の支持ビームは、周辺構造によって境界付けられた内部領域にまたがってもよい。
状の幾何学形状を有する。また、各支持ビームの断面幾何学形状は、実質的に丸みを帯びている。しかし、他の実施形態では、1つ以上の支持ビームは、長方形、多角形、規則的形状および/または不規則形状を含むがこれらに限定されない、任意の他の断面形状を有することができるであろう。断面形状は、支持ビームの長さにわたって、たとえば丸い断面形状(たとえば円形または楕円形)から、多角形断面形状(たとえば長方形)へと変化することもできるであろう。
いくつかの実施形態は、1つ以上の留め具受容手段(fastener receiving provisions
)を含むことができる。いくつかの実施形態は、挿入または埋め込みデバイスに係合してもよい1つ以上の取り付け開口を含んでもよい。いくつかの実施形態では、インプラントは、1つ以上のねじ切り空洞を含むことができる。いくつかの実施形態では、ねじ切り空洞を、埋め込みツールまたはデバイス上の対応するねじ山チップと嵌合するように構成することができる。他の実施形態では、ねじ切り空洞は、複数のインプラントおよび/または複数の構成要素を使用する埋め込みシステム内の別のデバイスまたは構成要素にインプラントを締結するための留め具を受容することができる。
いくつかの実施形態において、アーチ状骨接触要素は、第1端部、中間部および第2端部を含んでもよい。いくつかの実施形態において、中間部は、アーチ状幾何学形状を有していてもよい。そのような場合には、アーチ状幾何学形状を有する中間部を「アーチ状部分」と称してもよい。いくつかの実施形態では、第1端部および/または第2端部は、裾の広がった形状であるフレア状幾何学形状(flared geometry)を有することができるで
あろう。このような場合には、フレア状幾何学形状を有する端部を、アーチ状骨接触要素の「フレア状脚部」と称してもよい。
、第2支持ビーム254から第2外側側部158に延びている。
異なる実施形態では、インプラントの寸法を変えることができる。変えることができるであろう寸法の例として、長さ、幅および厚さが挙げられる。また、いくつかの場合には、1つ以上のアーチ状骨接触要素の直径を、実施形態によって変えることができるであろう。
たフットプリントを有するので、追加のアーチ状骨接触要素を、インプラント800の上側側部および下側側部により大きい(部分的)接触面を提供するために含んでもよい。図12~図13に示す実施形態では、これらの追加のアーチ状骨接触要素の一部は、本体部802の外側側部ならびに第1支持ビーム810、第2支持ビーム812および第3支持ビーム814に沿って追加される。
実施形態は、インプラントの1つ以上の表面をテクスチャ加工するための手段を含むことができる。このようなテクスチャ加工は、インプラントの表面への骨成長および/または癒合を増加させるなどして促進することができる。いくつかの実施形態では、アーチ状骨接触要素および/または本体部のセクションがテクスチャ加工されてもよい。
いくつかの実施形態では、骨成長は、インプラントの一部内またはインプラントの周囲に骨成長促進材料を適用することによって促進することができる。本明細書で用いられる場合、「骨成長促進材料」(またはBGPM)とは、骨の成長を助ける任意の材料である。骨成長促進材料は、リンカー分子またはバインダの使用により表面に凍結乾燥されるかまたは金属に付着される手段を含んでもよい。骨成長促進材料の例は、BMP-1、BMP-2、BMP-4、BMP-6およびBMP-7等の骨形成タンパク質(BMP)を含む、任意の材料である。これらは、幹細胞を骨形成細胞に変換するホルモンである。別の例には、rhBMP-2、rhBMP-4およびrhBMP-7等のリコンビナントヒトBMP(rhBMP)が挙げられる。さらに別の例には、血小板由来増殖因子(PDGF)、線維芽細胞増殖因子(FGF)、コラーゲン、BMP模倣ペプチド、およびRGDペプチドが挙げられる。一般に、これらの化学物質の組み合わせも使用してもよい。これらの化学物質は、スポンジ、基質またはゲルを使用して塗布することができる。
いくつかの実施形態では、インプラントは、開大式骨切除術処置の一部として、埋め込みのために構成されていてもよい。このような実施形態では、インプラントは、実質的にウェッジ形であってもよい。埋め込みを容易にするために、ウェッジの前縁(すなわち、狭い端部)は、実質的に滑らかな表面を有してもよい。また、細長い挿入ツールを受容するために、ウェッジの後縁(すなわち、厚い端部)は、モノリシック構造を有してもよい。モノリシック構造は、たとえばねじ式接続を介して挿入ツールを受容するように構成されたレセプタクルを含んでもよい。
タクルを含むことができる。いくつかの実施形態では、そのようなレセプタクルは、挿入または埋め込みツールに係合するように構成された雌ねじを含んでもよい。
い。すなわち、前縁は、前縁部の前縁面の実質的に大部分を形成する実質的に滑らかな表面を含んでもよい。
行われてもよい。このような骨切除術処置は、踵骨2405に凹部2410を形成してもよい。インプラント2200は、凹部2410に挿入するように構成(およびサイズ決め)されてもよい。
ウェッジ型インプラントは、他の外科的処置で使用されてもよい。たとえば、ウェッジ型インプラントは、仙腸関節の安定化処置において使用されてもよい。そのようなインプラントは、仙骨と腸骨との間の関節を固定または癒合するためにこれら2つの骨の間に挿入されてもよい。このようなインプラントは、挿入を容易にするための手段を有してもよい。たとえば、そのようなインプラントは、実質的にウェッジ形の構成を有していてもよく、挿入ツールに係合するように構成された丸面前縁とモノリシック後縁部とを含んでもよい。また、このようなインプラントは、骨内部成長を促進するための手段を有してもよい。たとえば、そのようなインプラントは、構造部材の間のスペースを画定するように配置された複数の細長い湾曲構造部材を含んでもよい。この開放構造が、細長い湾曲構造部材の間および細長い湾曲構造部材の周りでの骨内部成長を促進してもよい。
インプラントの種々の構成要素は、特定の用途および/または医師による選択に応じて、金属(たとえば、チタンまたは他の金属)、セラミック、および/またはそれらの組み合わせを含むがこれらに限定されない、人体に埋め込むのに好適な生体適合性材料から製造されてもよい。
F 1472))、および、ポリエーテルエーテルケトン(PEEK)などの不活性の生体適合性ポリマー(たとえばPEEK-OPTIMA(登録商標)、Invibio
Inc)を含む。任意選択的に、インプラントは、画像化中の可視化を容易にするためにX線不透過性マーカーを含む。
本開示によるインプラントは、以下の項目のリストに開示されたさまざまな特徴を含んでいてもよい。
求の範囲およびその均等物に鑑みる以外で制限されてはならない。また、添付の特許請求の範囲内で、種々の修正および変更を行ってもよい。
本願は、McShane III等の「Implant with Arched Bone Contacting Elements(アーチ
状骨接触要素を備えるインプラント)」と題された、2017年2月16日公開の米国特許出願公開第2017/0042697号(2016年10月25日出願の米国特許出願15/334,053号)の一部継続出願である。米国特許出願公開第2017/0042697号は、2015年4月29日に出願された米国仮出願第62/154,599号、2015年9月11日に出願された米国仮出願第62/217,542号および2016年2月29日に出願された米国仮出願第62/301,546号に基づく優先権を主張する、Morris等の「Coiled Implants and Systems and Methods Thereof(コイル状インプラントならびにそのシステムおよび方法)」と題された、2016年11月10日公開の米国公開第2016/0324656号(2016年4月28日出願の米国特許出願15/141,655号)の一部継続出願である。本願はまた、2016年10月25日に出願された米国仮出願第62/412,657号に基づく優先権を主張する。上記出願の各々は、参照により本明細書に援用される。
Claims (20)
- インプラントであって、
内部領域を境界付ける周辺構造と、前記内部領域を通って延びる少なくとも1本の支持ビームとを含む本体部と、
2つの端部を有する第1のアーチ状骨接触要素であって、前記2つの端部のうちの少なくとも1つが前記周辺構造に取り付けられている、前記第1のアーチ状骨接触要素とを含み、
ここで、前記第1のアーチ状骨接触要素は、アーチ状部分と、前記周辺構造に取り付けられた少なくとも1つのフレア状脚部とを含む、インプラント。 - 前記第1のアーチ状骨接触要素は、湾曲した中心軸を有し、前記第1のアーチ状骨接触要素の断面積は、前記湾曲した中心軸に沿って変化し、前記断面積は前記アーチ状部分で最小である。請求項1に記載のインプラント。
- 前記少なくとも1つのフレア状脚部が、前記本体部に取り付けられる第1の部分と、前記アーチ状部分に近接する第2の部分とを含み、
ここで、前記第1の部分は第1の断面形状を有し、前記第2の部分は前記第1の部分の断面形状とは異なる第2の断面形状を有する、請求項1に記載のインプラント。 - 前記第1の断面形状が楕円形であり、前記第2の断面形状が円形である、請求項3に記載のインプラント。
- 前記周辺構造に取り付けられた少なくとも1つの端部を有する第2のアーチ状骨接触要素をさらに含み、
ここで、前記第2のアーチ状骨接触要素は、アーチ状部分と、前記周辺構造に取り付けられた少なくとも1つのフレア状脚部とを含む、請求項1に記載のインプラント。 - 前記第2のアーチ状骨接触要素の少なくとも1つのフレア状脚部は、前記本体部に取り付けられる第1の部分と、前記第2のアーチ状骨接触要素の前記アーチ状部分に近接する第2の部分とを含み、
ここで、前記第2のアーチ状骨接触要素の第1の部分は、第1の断面形状を有し、前記第2の部分は、第2のアーチ状骨接触要素の前記第1の部分とは異なる第2の断面形状を有する、請求項5に記載のインプラント。 - 前記第2のアーチ状骨接触要素の前記第1の断面形状がほぼ楕円形であり、前記第2のアーチ状骨接触要素の前記第2の断面形状がほぼ円形である、請求項6に記載のインプラント。
- 前記第1のアーチ状骨接触要素が粗面化表面領域を含む、請求項1に記載のインプラント。
- それぞれのアーチ状骨接触要素が、インプラントの上面または下面からインプラントの内部領域に向かって骨の成長を促すように構成されている、請求項1に記載のインプラント。
- インプラントであって、
内部領域を境界付ける周辺構造と、前後軸に実質的に平行に前記内部領域を通って延びる第1の支持ビームとを有する本体部と、
両端部を有する第1のアーチ状骨接触要素であって、前記両端部がインプラントの前記本体部の前記周辺構造に取り付けられている、前記第1のアーチ状骨接触要素とを含む、インプラント。 - 前記第1のアーチ状骨接触要素の2つの端部のうちの少なくとも1つがフレア状脚部を形成する、請求項10に記載のインプラント。
- 前記フレア状脚部は、前記本体部に取り付けられる第1の部分と、前記第1のアーチ状骨接触要素のアーチ状部分に近接する第2の部分とを含み、
ここで、前記第1の部分は、第1の断面形状を有し、前記第2の部分は、前記第1の断面形状とは異なる第2の断面形状を有する、請求項11に記載のインプラント。 - 前記第1の断面形状が楕円形であり、前記第2の断面形状が円形である、請求項12に記載のインプラント。
- 両端部を有する第2のアーチ状骨接触要素であって、前記両端部がインプラントの前記本体部の前記周辺構造に取り付けられている、前記第2のアーチ状骨接触要素をさらに含む、請求項10に記載のインプラント。
- インプラントであって、
周辺構造と、第1の端部および第2の端部を有する第1の支持ビームとを備える本体部と、
前記周辺構造の一部から前記支持ビームの中間部分まで延びる第1のアーチ状骨接触要素と、
前記周辺構造の一部から前記支持ビームの中間部分まで延びる第2のアーチ状骨接触要素とを含み、
ここで、前記周辺構造は内部領域に接し、前記第1の支持ビームは、前記第1の支持ビームの第1の端部および第2の端部が両方とも前記本体部の前記周辺構造に接触するように前記内部領域をまたがり、
前記第1のアーチ状骨接触要素および前記第2のアーチ状骨接触要素は、互いに実質的に平行である、インプラント。 - 前記第1の支持ビームが実質的に真っ直ぐなビームである、請求項15に記載のインプラント。
- 前記周辺構造の一部から前記支持ビームの中間部分まで延びる第3のアーチ状骨接触要素を含み、
ここで、前記第3のアーチ状骨接触要素は、前記第1のアーチ状骨接触要素および前記第2のアーチ状骨接触要素に平行である、請求項15に記載のインプラント。 - 前記内部領域をまたがる第2の支持ビームをさらに含み、前記第1の支持ビームおよび前記第2の支持ビームがほぼ同一平面上にある、請求項15に記載のインプラント。
- 前記第1のアーチ状骨接触要素が、凸状骨接触領域を含む、請求項15に記載のインプラント。
- 前記周辺構造は、挿入デバイスと係合するための少なくとも1つの取付け開口部を含む、請求項15に記載のインプラント。
Applications Claiming Priority (8)
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JP7245780B2 (ja) | 2023-03-24 |
US10449051B2 (en) | 2019-10-22 |
BR112019008325A2 (pt) | 2019-10-15 |
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CN110418615A (zh) | 2019-11-05 |
EP3531942A4 (en) | 2020-10-07 |
EP3531942A1 (en) | 2019-09-04 |
US20180296347A1 (en) | 2018-10-18 |
JP2019531867A (ja) | 2019-11-07 |
US20200188120A1 (en) | 2020-06-18 |
US11819419B2 (en) | 2023-11-21 |
CN110418615B (zh) | 2023-04-21 |
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