JP2022008403A5 - - Google Patents
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- JP2022008403A5 JP2022008403A5 JP2021150116A JP2021150116A JP2022008403A5 JP 2022008403 A5 JP2022008403 A5 JP 2022008403A5 JP 2021150116 A JP2021150116 A JP 2021150116A JP 2021150116 A JP2021150116 A JP 2021150116A JP 2022008403 A5 JP2022008403 A5 JP 2022008403A5
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- JP
- Japan
- Prior art keywords
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- vision
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 13
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 6
- 230000004438 eyesight Effects 0.000 claims 5
- 239000011780 sodium chloride Substances 0.000 claims 5
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 5
- 229960000999 sodium citrate dihydrate Drugs 0.000 claims 5
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims 4
- 239000004327 boric acid Substances 0.000 claims 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 3
- 208000001491 myopia Diseases 0.000 claims 3
- 229920000642 polymer Polymers 0.000 claims 3
- 230000004304 visual acuity Effects 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- 238000000149 argon plasma sintering Methods 0.000 claims 1
- 230000004313 glare Effects 0.000 claims 1
- 230000004297 night vision Effects 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024062082A JP2024096131A (ja) | 2018-04-24 | 2024-04-08 | 眼の状態の治療のためのピロカルピン塩酸塩の使用 |
| JP2026069225A JP2026124816A (ja) | 2018-04-24 | 2026-04-20 | 眼の状態の治療のためのピロカルピン塩酸塩の使用 |
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862662144P | 2018-04-24 | 2018-04-24 | |
| US62/662,144 | 2018-04-24 | ||
| US201862780117P | 2018-12-14 | 2018-12-14 | |
| US62/780,117 | 2018-12-14 | ||
| US201962790957P | 2019-01-10 | 2019-01-10 | |
| US62/790,957 | 2019-01-10 | ||
| JP2020559558A JP6946575B2 (ja) | 2018-04-24 | 2019-04-24 | 眼の状態の治療のためのピロカルピン塩酸塩の使用 |
| PCT/US2019/028917 WO2019209955A2 (en) | 2018-04-24 | 2019-04-24 | Presbyopia treatments |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020559558A Division JP6946575B2 (ja) | 2018-04-24 | 2019-04-24 | 眼の状態の治療のためのピロカルピン塩酸塩の使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024062082A Division JP2024096131A (ja) | 2018-04-24 | 2024-04-08 | 眼の状態の治療のためのピロカルピン塩酸塩の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022008403A JP2022008403A (ja) | 2022-01-13 |
| JP2022008403A5 true JP2022008403A5 (enExample) | 2022-05-06 |
| JP7470667B2 JP7470667B2 (ja) | 2024-04-18 |
Family
ID=66821312
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020559558A Active JP6946575B2 (ja) | 2018-04-24 | 2019-04-24 | 眼の状態の治療のためのピロカルピン塩酸塩の使用 |
| JP2021150116A Active JP7470667B2 (ja) | 2018-04-24 | 2021-09-15 | 眼の状態の治療のためのピロカルピン塩酸塩の使用 |
| JP2024062082A Pending JP2024096131A (ja) | 2018-04-24 | 2024-04-08 | 眼の状態の治療のためのピロカルピン塩酸塩の使用 |
| JP2026069225A Pending JP2026124816A (ja) | 2018-04-24 | 2026-04-20 | 眼の状態の治療のためのピロカルピン塩酸塩の使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020559558A Active JP6946575B2 (ja) | 2018-04-24 | 2019-04-24 | 眼の状態の治療のためのピロカルピン塩酸塩の使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024062082A Pending JP2024096131A (ja) | 2018-04-24 | 2024-04-08 | 眼の状態の治療のためのピロカルピン塩酸塩の使用 |
| JP2026069225A Pending JP2026124816A (ja) | 2018-04-24 | 2026-04-20 | 眼の状態の治療のためのピロカルピン塩酸塩の使用 |
Country Status (25)
| Country | Link |
|---|---|
| US (5) | US10610518B2 (enExample) |
| EP (2) | EP4066830A1 (enExample) |
| JP (4) | JP6946575B2 (enExample) |
| KR (2) | KR20230079489A (enExample) |
| CN (1) | CN112272558A (enExample) |
| AU (3) | AU2019261598B9 (enExample) |
| BR (1) | BR112020021845A2 (enExample) |
| CA (2) | CA3074618C (enExample) |
| CL (1) | CL2020002734A1 (enExample) |
| CO (1) | CO2020014563A2 (enExample) |
| CY (1) | CY1125325T1 (enExample) |
| DK (1) | DK3681500T3 (enExample) |
| ES (1) | ES2920803T5 (enExample) |
| HR (1) | HRP20220762T1 (enExample) |
| HU (1) | HUE058931T2 (enExample) |
| IL (1) | IL278178A (enExample) |
| LT (1) | LT3681500T (enExample) |
| MX (1) | MX2020011301A (enExample) |
| PH (1) | PH12020551766A1 (enExample) |
| PL (1) | PL3681500T3 (enExample) |
| PT (1) | PT3681500T (enExample) |
| RS (1) | RS63360B1 (enExample) |
| SG (1) | SG11202010472XA (enExample) |
| SI (1) | SI3681500T1 (enExample) |
| WO (1) | WO2019209955A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12653779B2 (en) | 2015-06-18 | 2026-06-16 | Lenz Therapeutics Operations, Inc. | Compositions and methods for the treatment of presbyopia |
| EP3654964B1 (en) | 2017-07-20 | 2024-04-24 | Seinda Pharmaceutical Guangzhou Corporation | Composition comprising atropine and a miotic agent and its use in the treatment of myopia |
| US20210251970A1 (en) | 2018-10-10 | 2021-08-19 | Presbyopia Therapies Inc | Compositions and methods for storage stable ophthalmic drugs |
| JP2022508715A (ja) | 2018-10-15 | 2022-01-19 | オキュフィア・ファーマ・インコーポレイテッド | 緑内障および関連状態の処置のための方法および組成物 |
| DK3870170T3 (da) | 2018-10-26 | 2026-05-26 | Opus Genetics Inc | Behandling af presbyopi og mydriasis med fentolamin |
| BR112022026911A2 (pt) * | 2020-09-11 | 2023-03-28 | Intratus Nevada Inc | Composições e métodos para tratar presbiopia, hipermetropia, astigmatismo, diminuição da estereopsia e diminuição da sensibilidade ao contraste |
| US11872213B2 (en) | 2021-01-28 | 2024-01-16 | Glaukos Corporation | Formulations |
| WO2022232205A1 (en) * | 2021-04-28 | 2022-11-03 | Lenz Therapeutics, Inc. | A method of reducing brow ache |
| CN115368310B (zh) | 2021-05-18 | 2025-06-27 | 奥库菲尔医药公司 | 合成甲磺酸酚妥拉明的方法 |
| WO2023091439A1 (en) | 2021-11-17 | 2023-05-25 | Lenz Therapeutics, Inc. | Aceclidine derivatives, compositions thereof and methods of use thereof |
| US20250127760A1 (en) | 2021-12-28 | 2025-04-24 | Shenyang Xingqi Pharmaceutical Co., Ltd. | Composition and use thereof in preparation of medicament for treating presbyopia |
| US20230263727A1 (en) * | 2022-01-14 | 2023-08-24 | Somerset Therapeutics, Llc | Ophthalmologically suitable low pka buffer-containing pilocarpine compositions and related methods |
| US11969410B2 (en) | 2022-02-09 | 2024-04-30 | Somerset Therapeutics, Llc | Low pH pilocarpine and brimonidine compound formulations and related methods |
| AU2023257375A1 (en) | 2022-04-21 | 2024-11-07 | Glaukos Corporation | Ophthalmic topical cream compositions |
| AU2023273823A1 (en) | 2022-05-18 | 2024-12-05 | Glaukos Corporation | Novel applications of zwitterions in ophthalmic topical cream compositions and preparations |
| CN117243888A (zh) * | 2023-09-22 | 2023-12-19 | 南京海纳制药有限公司 | 一种含有盐酸毛果芸香碱滴眼水性药物组合物及其制备方法 |
| CN119700989A (zh) | 2023-09-28 | 2025-03-28 | 苏州普乐康医药科技有限公司 | 一种α-肾上腺素受体激动剂眼用组合物及其用途 |
| US12414942B1 (en) | 2024-03-15 | 2025-09-16 | Lenz Therapeutics Operations, Inc. | Compositions, methods, and systems for treating presbyopia |
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-
2019
- 2019-04-24 JP JP2020559558A patent/JP6946575B2/ja active Active
- 2019-04-24 HR HRP20220762TT patent/HRP20220762T1/hr unknown
- 2019-04-24 PL PL19729883.9T patent/PL3681500T3/pl unknown
- 2019-04-24 US US16/393,175 patent/US10610518B2/en active Active
- 2019-04-24 EP EP22160205.5A patent/EP4066830A1/en not_active Withdrawn
- 2019-04-24 CN CN201980037652.3A patent/CN112272558A/zh active Pending
- 2019-04-24 HU HUE19729883A patent/HUE058931T2/hu unknown
- 2019-04-24 CA CA3074618A patent/CA3074618C/en active Active
- 2019-04-24 KR KR1020237017632A patent/KR20230079489A/ko active Pending
- 2019-04-24 CA CA3162141A patent/CA3162141A1/en active Pending
- 2019-04-24 BR BR112020021845-6A patent/BR112020021845A2/pt not_active IP Right Cessation
- 2019-04-24 DK DK19729883.9T patent/DK3681500T3/da active
- 2019-04-24 KR KR1020207033656A patent/KR20210005134A/ko not_active Ceased
- 2019-04-24 LT LTEPPCT/US2019/028917T patent/LT3681500T/lt unknown
- 2019-04-24 MX MX2020011301A patent/MX2020011301A/es unknown
- 2019-04-24 ES ES19729883T patent/ES2920803T5/es active Active
- 2019-04-24 RS RS20220575A patent/RS63360B1/sr unknown
- 2019-04-24 EP EP19729883.9A patent/EP3681500B2/en active Active
- 2019-04-24 AU AU2019261598A patent/AU2019261598B9/en not_active Ceased
- 2019-04-24 SG SG11202010472XA patent/SG11202010472XA/en unknown
- 2019-04-24 PT PT197298839T patent/PT3681500T/pt unknown
- 2019-04-24 SI SI201930260T patent/SI3681500T1/sl unknown
- 2019-04-24 WO PCT/US2019/028917 patent/WO2019209955A2/en not_active Ceased
-
2020
- 2020-02-14 US US16/791,039 patent/US11285134B2/en active Active
- 2020-05-21 AU AU2020203311A patent/AU2020203311A1/en not_active Abandoned
- 2020-10-20 IL IL278178A patent/IL278178A/en unknown
- 2020-10-22 CL CL2020002734A patent/CL2020002734A1/es unknown
- 2020-10-23 PH PH12020551766A patent/PH12020551766A1/en unknown
- 2020-11-24 CO CONC2020/0014563A patent/CO2020014563A2/es unknown
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2021
- 2021-09-15 JP JP2021150116A patent/JP7470667B2/ja active Active
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2022
- 2022-01-12 US US17/647,813 patent/US20220241245A1/en not_active Abandoned
- 2022-02-18 AU AU2022201106A patent/AU2022201106A1/en not_active Abandoned
- 2022-06-22 CY CY20221100430T patent/CY1125325T1/el unknown
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2024
- 2024-03-29 US US18/621,624 patent/US20240382462A1/en not_active Abandoned
- 2024-04-08 JP JP2024062082A patent/JP2024096131A/ja active Pending
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2025
- 2025-09-05 US US19/320,113 patent/US20260124178A1/en active Pending
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2026
- 2026-04-20 JP JP2026069225A patent/JP2026124816A/ja active Pending
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