JP2021534138A5 - - Google Patents
Info
- Publication number
- JP2021534138A5 JP2021534138A5 JP2021507456A JP2021507456A JP2021534138A5 JP 2021534138 A5 JP2021534138 A5 JP 2021534138A5 JP 2021507456 A JP2021507456 A JP 2021507456A JP 2021507456 A JP2021507456 A JP 2021507456A JP 2021534138 A5 JP2021534138 A5 JP 2021534138A5
- Authority
- JP
- Japan
- Prior art keywords
- xrpd
- peaks
- omecamutib
- cukα irradiation
- pattern
- Prior art date
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024090471A JP2024123028A (ja) | 2018-08-17 | 2024-06-04 | オメカムチブメカルビルの塩及び結晶形態 |
| JP2025066074A JP2025108571A (ja) | 2018-08-17 | 2025-04-14 | オメカムチブメカルビルの塩及び結晶形態 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862765090P | 2018-08-17 | 2018-08-17 | |
| US62/765,090 | 2018-08-17 | ||
| PCT/US2019/046726 WO2020037164A1 (en) | 2018-08-17 | 2019-08-16 | Salts and crystal forms of omecamtiv mecarbil |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024090471A Division JP2024123028A (ja) | 2018-08-17 | 2024-06-04 | オメカムチブメカルビルの塩及び結晶形態 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021534138A JP2021534138A (ja) | 2021-12-09 |
| JP2021534138A5 true JP2021534138A5 (https=) | 2022-08-22 |
| JPWO2020037164A5 JPWO2020037164A5 (https=) | 2022-08-22 |
Family
ID=67809688
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021507456A Pending JP2021534138A (ja) | 2018-08-17 | 2019-08-16 | オメカムチブメカルビルの塩及び結晶形態 |
| JP2024090471A Withdrawn JP2024123028A (ja) | 2018-08-17 | 2024-06-04 | オメカムチブメカルビルの塩及び結晶形態 |
| JP2025066074A Pending JP2025108571A (ja) | 2018-08-17 | 2025-04-14 | オメカムチブメカルビルの塩及び結晶形態 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024090471A Withdrawn JP2024123028A (ja) | 2018-08-17 | 2024-06-04 | オメカムチブメカルビルの塩及び結晶形態 |
| JP2025066074A Pending JP2025108571A (ja) | 2018-08-17 | 2025-04-14 | オメカムチブメカルビルの塩及び結晶形態 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11465969B2 (https=) |
| EP (1) | EP3837009A1 (https=) |
| JP (3) | JP2021534138A (https=) |
| AU (2) | AU2019321573B2 (https=) |
| CA (1) | CA3108800A1 (https=) |
| MA (1) | MA53226A (https=) |
| MX (2) | MX2021001792A (https=) |
| WO (1) | WO2020037164A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5080970B2 (ja) | 2004-06-17 | 2012-11-21 | サイトキネティクス・インコーポレーテッド | 心疾患を治療するための置換尿素誘導体 |
| DK2970123T4 (da) | 2013-03-14 | 2026-01-26 | Amgen Inc | Krystallinsk dihydrochloridhydratsalt af omecamtiv mecarbil og fremgangsmåde til fremstilling heraf |
| SMT202100472T1 (it) | 2017-06-30 | 2021-09-14 | Amgen Inc | Sintesi di omecamtiv mecarbil |
| EP4512470A3 (en) | 2017-06-30 | 2025-04-23 | Amgen Inc. | Methods of treating heart failure with cardiac sarcomere activators |
| AU2018332887B2 (en) | 2017-09-13 | 2022-12-08 | Amgen Inc. | Bisamide sarcomere activating compounds and uses thereof |
| EP3594199B1 (en) | 2018-07-09 | 2020-07-01 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Crystalline 2-fluoro-3-nitrotoluene and process for the preparation thereof |
| JP2021534138A (ja) * | 2018-08-17 | 2021-12-09 | アムジエン・インコーポレーテツド | オメカムチブメカルビルの塩及び結晶形態 |
| WO2020131574A1 (en) | 2018-12-18 | 2020-06-25 | Amgen Inc. | Method of reducing aromatic nitro compounds |
| US20220348543A1 (en) * | 2019-09-19 | 2022-11-03 | Synthon B.V. | Salts of omecamtiv mecarbil and solid forms thereof |
| EP4031541A1 (en) * | 2019-09-19 | 2022-07-27 | Synthon B.V. | Salts of omecamtiv mecarbil and solid forms thereof |
| US20220402874A1 (en) * | 2019-10-09 | 2022-12-22 | Dr. Reddy's Laboratories Limited | Solid forms of omecamtiv mecarbil dihydrochloride and processes thereof |
| US12194039B2 (en) | 2020-11-12 | 2025-01-14 | Amgen Inc | Methods of treating heart failure by administering omecamtiv mecarbil |
| WO2022177927A1 (en) | 2021-02-16 | 2022-08-25 | Assia Chemical Industries Ltd | Unhydrous crystalline form of omecamtiv mecarbil dihydrobromide salt |
| JP7843295B2 (ja) | 2021-03-10 | 2026-04-09 | アムジェン インコーポレイテッド | オメカムチブメカルビルの合成 |
| US11986474B1 (en) | 2023-06-27 | 2024-05-21 | Cytokinetics, Incorporated | Methods for treating heart failure by administering cardiac sarcomere activators |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| JP5080970B2 (ja) | 2004-06-17 | 2012-11-21 | サイトキネティクス・インコーポレーテッド | 心疾患を治療するための置換尿素誘導体 |
| TW200808321A (en) | 2005-12-15 | 2008-02-16 | Cytokinetics Inc | Certain chemical entities, compositions and methods |
| US20090192168A1 (en) * | 2008-01-04 | 2009-07-30 | Alex Muci | Compounds, Compositions and Methods |
| CA2902424A1 (en) | 2013-03-14 | 2014-09-25 | Amgen Inc. | Heterocyclic compounds and their uses |
| DK2970123T4 (da) | 2013-03-14 | 2026-01-26 | Amgen Inc | Krystallinsk dihydrochloridhydratsalt af omecamtiv mecarbil og fremgangsmåde til fremstilling heraf |
| WO2016123291A1 (en) | 2015-01-29 | 2016-08-04 | Signal Pharmaceuticals, Llc | Isotopologues of 2-(tert-butylamino)-4-((1r,3r,4r)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide |
| MX379899B (es) | 2015-06-26 | 2025-03-11 | Cytokinetics Inc | Terapia de combinacion de activador de miosina cardiaca e inhibidor de corriente if del nodo sinusal |
| EP4512470A3 (en) | 2017-06-30 | 2025-04-23 | Amgen Inc. | Methods of treating heart failure with cardiac sarcomere activators |
| SMT202100472T1 (it) | 2017-06-30 | 2021-09-14 | Amgen Inc | Sintesi di omecamtiv mecarbil |
| EP3594199B1 (en) | 2018-07-09 | 2020-07-01 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Crystalline 2-fluoro-3-nitrotoluene and process for the preparation thereof |
| US11608318B2 (en) | 2018-07-12 | 2023-03-21 | Assia Chemical Industries Ltd. | Solid state forms of Omecamtiv mecarbil and Omecamtiv mecarbil diHCl |
| JP2021534138A (ja) * | 2018-08-17 | 2021-12-09 | アムジエン・インコーポレーテツド | オメカムチブメカルビルの塩及び結晶形態 |
| WO2020131574A1 (en) | 2018-12-18 | 2020-06-25 | Amgen Inc. | Method of reducing aromatic nitro compounds |
| EP4031541A1 (en) | 2019-09-19 | 2022-07-27 | Synthon B.V. | Salts of omecamtiv mecarbil and solid forms thereof |
| US20220348543A1 (en) | 2019-09-19 | 2022-11-03 | Synthon B.V. | Salts of omecamtiv mecarbil and solid forms thereof |
| WO2021070124A1 (en) | 2019-10-09 | 2021-04-15 | Dr. Reddy’S Laboratories Limited | Alternate processes for the preparation of omecamtiv mecarbil |
| US20220402874A1 (en) | 2019-10-09 | 2022-12-22 | Dr. Reddy's Laboratories Limited | Solid forms of omecamtiv mecarbil dihydrochloride and processes thereof |
| CN114929671B (zh) | 2020-01-03 | 2024-04-16 | 苏州科睿思制药有限公司 | 化合物i二盐酸盐的共晶及其制备方法和用途 |
| CN115279349A (zh) | 2020-02-10 | 2022-11-01 | 安进股份有限公司 | 奥美卡替莫卡必尔片剂 |
| US12194039B2 (en) | 2020-11-12 | 2025-01-14 | Amgen Inc | Methods of treating heart failure by administering omecamtiv mecarbil |
| JP7843295B2 (ja) | 2021-03-10 | 2026-04-09 | アムジェン インコーポレイテッド | オメカムチブメカルビルの合成 |
-
2019
- 2019-08-16 JP JP2021507456A patent/JP2021534138A/ja active Pending
- 2019-08-16 WO PCT/US2019/046726 patent/WO2020037164A1/en not_active Ceased
- 2019-08-16 US US17/263,224 patent/US11465969B2/en active Active
- 2019-08-16 MX MX2021001792A patent/MX2021001792A/es unknown
- 2019-08-16 EP EP19762026.3A patent/EP3837009A1/en active Pending
- 2019-08-16 AU AU2019321573A patent/AU2019321573B2/en active Active
- 2019-08-16 MA MA053226A patent/MA53226A/fr unknown
- 2019-08-16 CA CA3108800A patent/CA3108800A1/en active Pending
-
2021
- 2021-02-12 MX MX2023013372A patent/MX2023013372A/es unknown
-
2022
- 2022-09-02 US US17/929,645 patent/US11926592B2/en active Active
-
2024
- 2024-06-04 JP JP2024090471A patent/JP2024123028A/ja not_active Withdrawn
-
2025
- 2025-04-14 JP JP2025066074A patent/JP2025108571A/ja active Pending
- 2025-05-29 AU AU2025204014A patent/AU2025204014A1/en active Pending
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