JP2021533134A5 - - Google Patents
Info
- Publication number
- JP2021533134A5 JP2021533134A5 JP2021505847A JP2021505847A JP2021533134A5 JP 2021533134 A5 JP2021533134 A5 JP 2021533134A5 JP 2021505847 A JP2021505847 A JP 2021505847A JP 2021505847 A JP2021505847 A JP 2021505847A JP 2021533134 A5 JP2021533134 A5 JP 2021533134A5
- Authority
- JP
- Japan
- Prior art keywords
- conhch
- och
- group
- cells
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862713823P | 2018-08-02 | 2018-08-02 | |
| US62/713,823 | 2018-08-02 | ||
| PCT/US2019/044421 WO2020028532A1 (en) | 2018-08-02 | 2019-07-31 | Adjuvant effect of the tlr1/2 agonist diprovocim synergizes with checkpoint-inhibiting antibodies to eliminate disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021533134A JP2021533134A (ja) | 2021-12-02 |
| JP2021533134A5 true JP2021533134A5 (https=) | 2022-09-22 |
Family
ID=69232110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021505847A Pending JP2021533134A (ja) | 2018-08-02 | 2019-07-31 | チェックポイント阻害抗体と相乗効果を示し、疾患を排除するｔｌｒ１／２アゴニストジプロボッシムのアジュバント効果 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20210315992A1 (https=) |
| EP (1) | EP3829571B1 (https=) |
| JP (1) | JP2021533134A (https=) |
| KR (1) | KR20210029280A (https=) |
| CN (1) | CN113164445A (https=) |
| AU (2) | AU2019315952A1 (https=) |
| BR (1) | BR112021001992A2 (https=) |
| CA (1) | CA3108515A1 (https=) |
| IL (1) | IL280584B2 (https=) |
| WO (1) | WO2020028532A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4103283A4 (en) | 2020-03-26 | 2024-02-28 | Provectus Pharmatech, Inc. | NEW USES OF HALOGENATED XANTHENES IN ONCOLOGY AND VIROLOGY |
| US11938182B2 (en) | 2020-03-26 | 2024-03-26 | Provectus Pharmatech, Inc. | Halogenated xanthenes as vaccine adjuvants |
| JP2023527792A (ja) | 2020-05-27 | 2023-06-30 | アキシャル セラピューティクス，インク． | Ｔｌｒ２調節剤化合物、医薬組成物、及びそれらの使用 |
| CN115697363A (zh) * | 2020-07-14 | 2023-02-03 | Dic株式会社 | 细胞杀伤性t细胞(ctl)活化用组合物 |
| US20250367166A1 (en) * | 2022-04-29 | 2025-12-04 | The Scripps Research Institute | Next generation diprovocims that activate the innate and adaptive immune response |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4599231A (en) | 1984-03-09 | 1986-07-08 | Scripps Clinic And Research Foundation | Synthetic hepatitis B virus vaccine including both T cell and B cell determinants |
| US5180806A (en) | 1988-05-16 | 1993-01-19 | The Scripps Research Institute | Polypeptides and compositions of human papillomavirus latent proteins, diagnostic systems and methods |
| AU3386400A (en) | 1999-03-02 | 2000-09-21 | Merck & Co., Inc. | 3-alkyl substituted pyrrolidine modulators of chemokine receptor activity |
| US6942866B2 (en) | 2000-08-16 | 2005-09-13 | Apovia, Inc. | Malaria immunogen and vaccine |
| JP4472333B2 (ja) * | 2001-08-08 | 2010-06-02 | ペントラキシン セラピューティクス リミテッド | 好ましくないタンパク質群を患者の血漿から除去するための薬剤 |
| US7361352B2 (en) | 2001-08-15 | 2008-04-22 | Acambis, Inc. | Influenza immunogen and vaccine |
| EP2441846A3 (en) * | 2006-01-09 | 2012-07-25 | The Regents Of the University of California | Immunostimulatory combinations of TNFRSF, TLR, NLR, RHR, purinergic receptor, and cytokine receptor agoinsts for vaccines and tumor immunotherapy |
| WO2014163684A1 (en) * | 2013-04-03 | 2014-10-09 | Ibc Pharmaceuticals, Inc. | Combination therapy for inducing immune response to disease |
| ES2944541T3 (es) * | 2014-08-06 | 2023-06-22 | Scripps Research Inst | Adyuvantes de molécula pequeña independientes de TLR |
| WO2016123285A1 (en) * | 2015-01-29 | 2016-08-04 | The Trustees Of The University Of Pennsylvania | Checkpoint inhibitor and vaccine combinations and use of same for immunotherapy |
| JP6961490B2 (ja) * | 2015-04-08 | 2021-11-05 | ノバルティス アーゲー | Ｃｄ２０療法、ｃｄ２２療法、およびｃｄ１９キメラ抗原受容体（ｃａｒ）発現細胞との併用療法 |
| JP2019513373A (ja) * | 2016-03-31 | 2019-05-30 | ネオン セラピューティクス， インコーポレイテッド | ネオ抗原およびその使用方法 |
| CA3026178C (en) * | 2016-06-29 | 2024-05-21 | The Scripps Research Institute | Diprovocims: a new and potent class of tlr agonists |
| US20180088749A1 (en) | 2016-09-26 | 2018-03-29 | Uber Technologies, Inc. | Customized content generation for a user interface for a network service |
| US20180169224A1 (en) * | 2016-12-12 | 2018-06-21 | Wisconsin Alumni Research Foundation | Tlr agonists for reducing activation-induced pd-1 expression on t cells and methods of use |
-
2019
- 2019-07-31 BR BR112021001992-8A patent/BR112021001992A2/pt unknown
- 2019-07-31 CN CN201980065609.8A patent/CN113164445A/zh active Pending
- 2019-07-31 WO PCT/US2019/044421 patent/WO2020028532A1/en not_active Ceased
- 2019-07-31 CA CA3108515A patent/CA3108515A1/en active Pending
- 2019-07-31 IL IL280584A patent/IL280584B2/en unknown
- 2019-07-31 AU AU2019315952A patent/AU2019315952A1/en not_active Abandoned
- 2019-07-31 JP JP2021505847A patent/JP2021533134A/ja active Pending
- 2019-07-31 EP EP19844778.1A patent/EP3829571B1/en active Active
- 2019-07-31 US US17/265,333 patent/US20210315992A1/en active Pending
- 2019-07-31 KR KR1020217006180A patent/KR20210029280A/ko not_active Ceased
-
2025
- 2025-06-03 AU AU2025204146A patent/AU2025204146A1/en active Pending
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