KR20210029280A - 질환을 제거하기 위한 체크포인트-억제 항체와 상승작용하는 tlr1/2 작용제 디프로보심의 애쥬번트 효과 - Google Patents

질환을 제거하기 위한 체크포인트-억제 항체와 상승작용하는 tlr1/2 작용제 디프로보심의 애쥬번트 효과 Download PDF

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KR20210029280A
KR20210029280A KR1020217006180A KR20217006180A KR20210029280A KR 20210029280 A KR20210029280 A KR 20210029280A KR 1020217006180 A KR1020217006180 A KR 1020217006180A KR 20217006180 A KR20217006180 A KR 20217006180A KR 20210029280 A KR20210029280 A KR 20210029280A
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cells
diprovosim
asn
conhch
tumor
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브루스 버틀러
잉 왕
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보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템
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KR1020217006180A 2018-08-02 2019-07-31 질환을 제거하기 위한 체크포인트-억제 항체와 상승작용하는 tlr1/2 작용제 디프로보심의 애쥬번트 효과 Ceased KR20210029280A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862713823P 2018-08-02 2018-08-02
US62/713,823 2018-08-02
PCT/US2019/044421 WO2020028532A1 (en) 2018-08-02 2019-07-31 Adjuvant effect of the tlr1/2 agonist diprovocim synergizes with checkpoint-inhibiting antibodies to eliminate disease

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KR20210029280A true KR20210029280A (ko) 2021-03-15

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KR1020217006180A Ceased KR20210029280A (ko) 2018-08-02 2019-07-31 질환을 제거하기 위한 체크포인트-억제 항체와 상승작용하는 tlr1/2 작용제 디프로보심의 애쥬번트 효과

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US (1) US20210315992A1 (https=)
EP (1) EP3829571B1 (https=)
JP (1) JP2021533134A (https=)
KR (1) KR20210029280A (https=)
CN (1) CN113164445A (https=)
AU (2) AU2019315952A1 (https=)
BR (1) BR112021001992A2 (https=)
CA (1) CA3108515A1 (https=)
IL (1) IL280584B2 (https=)
WO (1) WO2020028532A1 (https=)

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US11938182B2 (en) 2020-03-26 2024-03-26 Provectus Pharmatech, Inc. Halogenated xanthenes as vaccine adjuvants
MX2022011765A (es) 2020-03-26 2022-11-09 Provectus Pharmatech Inc Usos novedosos de xantenos halogenados en oncologia y virologia.
JP2023527792A (ja) 2020-05-27 2023-06-30 アキシャル セラピューティクス，インク． Ｔｌｒ２調節剤化合物、医薬組成物、及びそれらの使用
CN115697363A (zh) * 2020-07-14 2023-02-03 Dic株式会社 细胞杀伤性t细胞(ctl)活化用组合物
US20250367166A1 (en) * 2022-04-29 2025-12-04 The Scripps Research Institute Next generation diprovocims that activate the innate and adaptive immune response

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US4599231A (en) 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US5180806A (en) 1988-05-16 1993-01-19 The Scripps Research Institute Polypeptides and compositions of human papillomavirus latent proteins, diagnostic systems and methods
US6489354B1 (en) 1999-03-02 2002-12-03 Merck & Co., Inc. 3-alkyl substituted pyrrolidine modulators of chemokine receptor activity
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DK1418905T3 (da) * 2001-08-08 2007-09-10 Pentraxin Therapeutics Ltd Terapeutisk middel til depletering af en uönsket proteinpopulation fra plasma
US7361352B2 (en) 2001-08-15 2008-04-22 Acambis, Inc. Influenza immunogen and vaccine
CA2636424A1 (en) * 2006-01-09 2007-10-25 The Regents Of The University Of California Immunostimulatory combinations of tnfrsf, tlr, nlr, rhr, purinergic receptor, and cytokine receptor agonists for vaccines and tumor immunotherapy
EP2981281B1 (en) * 2013-04-03 2020-07-15 IBC Pharmaceuticals, Inc. Combination therapy for inducing immune response to disease
US9918959B2 (en) * 2014-08-06 2018-03-20 The Board Of Regents Of The University Of Texas System TLR-independent small molecule adjuvants
CA2974956A1 (en) * 2015-01-29 2016-08-04 The Trustees Of The University Of Pennsylvania Checkpoint inhibitor and vaccine combinations and use of same for immunotherapy
MX2017012939A (es) * 2015-04-08 2018-05-22 Novartis Ag Terapias cd20, terapias cd22 y terapias de combinacion con una celula que expresa un receptor quimerico de antigeno (car) de cd19.
FI3436048T3 (fi) * 2016-03-31 2025-09-15 Biontech Us Inc Neoantigeeneja ja niiden käyttömenetelmiä
KR102522730B1 (ko) 2016-06-29 2023-04-19 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 디프로보심: 새로운 강력한 부류의 tlr 작용제
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US20180169224A1 (en) 2016-12-12 2018-06-21 Wisconsin Alumni Research Foundation Tlr agonists for reducing activation-induced pd-1 expression on t cells and methods of use

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JP2021533134A (ja) 2021-12-02
WO2020028532A1 (en) 2020-02-06
US20210315992A1 (en) 2021-10-14
AU2019315952A1 (en) 2021-03-04
IL280584B1 (en) 2025-02-01
AU2025204146A1 (en) 2025-07-17
AU2025204146A9 (en) 2026-03-19
EP3829571C0 (en) 2025-04-09
BR112021001992A2 (pt) 2021-05-04
EP3829571A1 (en) 2021-06-09
CA3108515A1 (en) 2020-02-06
EP3829571B1 (en) 2025-04-09
IL280584B2 (en) 2025-06-01
CN113164445A (zh) 2021-07-23
IL280584A (en) 2021-03-25
EP3829571A4 (en) 2022-04-27

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