BR112021001992A2 - efeito adjuvante do agonista tlr1/2 diprovocim sinergiza com anticorpos inibidores de checkpoint para eliminar doença - Google Patents
efeito adjuvante do agonista tlr1/2 diprovocim sinergiza com anticorpos inibidores de checkpoint para eliminar doença Download PDFInfo
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Applications Claiming Priority (3)
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| US201862713823P | 2018-08-02 | 2018-08-02 | |
| US62/713,823 | 2018-08-02 | ||
| PCT/US2019/044421 WO2020028532A1 (en) | 2018-08-02 | 2019-07-31 | Adjuvant effect of the tlr1/2 agonist diprovocim synergizes with checkpoint-inhibiting antibodies to eliminate disease |
Publications (1)
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| BR112021001992A2 true BR112021001992A2 (pt) | 2021-05-04 |
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| US (1) | US20210315992A1 (https=) |
| EP (1) | EP3829571B1 (https=) |
| JP (1) | JP2021533134A (https=) |
| KR (1) | KR20210029280A (https=) |
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| CA (1) | CA3108515A1 (https=) |
| IL (1) | IL280584B2 (https=) |
| WO (1) | WO2020028532A1 (https=) |
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| US11938182B2 (en) | 2020-03-26 | 2024-03-26 | Provectus Pharmatech, Inc. | Halogenated xanthenes as vaccine adjuvants |
| MX2022011765A (es) | 2020-03-26 | 2022-11-09 | Provectus Pharmatech Inc | Usos novedosos de xantenos halogenados en oncologia y virologia. |
| JP2023527792A (ja) | 2020-05-27 | 2023-06-30 | アキシャル セラピューティクス，インク． | Ｔｌｒ２調節剤化合物、医薬組成物、及びそれらの使用 |
| CN115697363A (zh) * | 2020-07-14 | 2023-02-03 | Dic株式会社 | 细胞杀伤性t细胞(ctl)活化用组合物 |
| US20250367166A1 (en) * | 2022-04-29 | 2025-12-04 | The Scripps Research Institute | Next generation diprovocims that activate the innate and adaptive immune response |
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| US4599231A (en) | 1984-03-09 | 1986-07-08 | Scripps Clinic And Research Foundation | Synthetic hepatitis B virus vaccine including both T cell and B cell determinants |
| US5180806A (en) | 1988-05-16 | 1993-01-19 | The Scripps Research Institute | Polypeptides and compositions of human papillomavirus latent proteins, diagnostic systems and methods |
| US6489354B1 (en) | 1999-03-02 | 2002-12-03 | Merck & Co., Inc. | 3-alkyl substituted pyrrolidine modulators of chemokine receptor activity |
| US6942866B2 (en) | 2000-08-16 | 2005-09-13 | Apovia, Inc. | Malaria immunogen and vaccine |
| DK1418905T3 (da) * | 2001-08-08 | 2007-09-10 | Pentraxin Therapeutics Ltd | Terapeutisk middel til depletering af en uönsket proteinpopulation fra plasma |
| US7361352B2 (en) | 2001-08-15 | 2008-04-22 | Acambis, Inc. | Influenza immunogen and vaccine |
| CA2636424A1 (en) * | 2006-01-09 | 2007-10-25 | The Regents Of The University Of California | Immunostimulatory combinations of tnfrsf, tlr, nlr, rhr, purinergic receptor, and cytokine receptor agonists for vaccines and tumor immunotherapy |
| EP2981281B1 (en) * | 2013-04-03 | 2020-07-15 | IBC Pharmaceuticals, Inc. | Combination therapy for inducing immune response to disease |
| US9918959B2 (en) * | 2014-08-06 | 2018-03-20 | The Board Of Regents Of The University Of Texas System | TLR-independent small molecule adjuvants |
| CA2974956A1 (en) * | 2015-01-29 | 2016-08-04 | The Trustees Of The University Of Pennsylvania | Checkpoint inhibitor and vaccine combinations and use of same for immunotherapy |
| MX2017012939A (es) * | 2015-04-08 | 2018-05-22 | Novartis Ag | Terapias cd20, terapias cd22 y terapias de combinacion con una celula que expresa un receptor quimerico de antigeno (car) de cd19. |
| FI3436048T3 (fi) * | 2016-03-31 | 2025-09-15 | Biontech Us Inc | Neoantigeeneja ja niiden käyttömenetelmiä |
| KR102522730B1 (ko) | 2016-06-29 | 2023-04-19 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 디프로보심: 새로운 강력한 부류의 tlr 작용제 |
| US20180088749A1 (en) | 2016-09-26 | 2018-03-29 | Uber Technologies, Inc. | Customized content generation for a user interface for a network service |
| US20180169224A1 (en) | 2016-12-12 | 2018-06-21 | Wisconsin Alumni Research Foundation | Tlr agonists for reducing activation-induced pd-1 expression on t cells and methods of use |
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- 2019-07-31 AU AU2019315952A patent/AU2019315952A1/en not_active Abandoned
- 2019-07-31 EP EP19844778.1A patent/EP3829571B1/en active Active
- 2019-07-31 BR BR112021001992-8A patent/BR112021001992A2/pt unknown
- 2019-07-31 US US17/265,333 patent/US20210315992A1/en active Pending
- 2019-07-31 IL IL280584A patent/IL280584B2/en unknown
- 2019-07-31 KR KR1020217006180A patent/KR20210029280A/ko not_active Ceased
- 2019-07-31 JP JP2021505847A patent/JP2021533134A/ja active Pending
- 2019-07-31 WO PCT/US2019/044421 patent/WO2020028532A1/en not_active Ceased
- 2019-07-31 CA CA3108515A patent/CA3108515A1/en active Pending
-
2025
- 2025-06-03 AU AU2025204146A patent/AU2025204146A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2021533134A (ja) | 2021-12-02 |
| WO2020028532A1 (en) | 2020-02-06 |
| US20210315992A1 (en) | 2021-10-14 |
| AU2019315952A1 (en) | 2021-03-04 |
| IL280584B1 (en) | 2025-02-01 |
| AU2025204146A1 (en) | 2025-07-17 |
| KR20210029280A (ko) | 2021-03-15 |
| AU2025204146A9 (en) | 2026-03-19 |
| EP3829571C0 (en) | 2025-04-09 |
| EP3829571A1 (en) | 2021-06-09 |
| CA3108515A1 (en) | 2020-02-06 |
| EP3829571B1 (en) | 2025-04-09 |
| IL280584B2 (en) | 2025-06-01 |
| CN113164445A (zh) | 2021-07-23 |
| IL280584A (en) | 2021-03-25 |
| EP3829571A4 (en) | 2022-04-27 |
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| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] |