|
BR112014015197A8
(pt)
|
2011-12-21 |
2017-06-13 |
Novira Therapeutics Inc |
agentes antivirais de hepatite b
|
|
KR102271574B1
(ko)
|
2012-08-28 |
2021-07-01 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
설파모일-아릴아미드 및 b형 간염 치료제로서의 그 용도
|
|
HK1215030A1
(zh)
*
|
2012-11-09 |
2016-08-12 |
Indiana University Research And Technology Corporation |
用於hbv組裝效應劑的替代用途
|
|
EP3031921B1
(en)
|
2012-12-12 |
2025-03-12 |
The Broad Institute, Inc. |
Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
|
|
EP2931899A1
(en)
|
2012-12-12 |
2015-10-21 |
The Broad Institute, Inc. |
Functional genomics using crispr-cas systems, compositions, methods, knock out libraries and applications thereof
|
|
WO2014093709A1
(en)
|
2012-12-12 |
2014-06-19 |
The Broad Institute, Inc. |
Methods, models, systems, and apparatus for identifying target sequences for cas enzymes or crispr-cas systems for target sequences and conveying results thereof
|
|
WO2014131847A1
(en)
|
2013-02-28 |
2014-09-04 |
Janssen R&D Ireland |
Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis b
|
|
US8993771B2
(en)
|
2013-03-12 |
2015-03-31 |
Novira Therapeutics, Inc. |
Hepatitis B antiviral agents
|
|
MX353412B
(es)
|
2013-04-03 |
2018-01-10 |
Janssen Sciences Ireland Uc |
Derivados de n-fenil-carboxamida y su uso como medicamentos para el tratamiento de la hepatitis b.
|
|
TWI733288B
(zh)
|
2013-05-17 |
2021-07-11 |
愛爾蘭商健生科學愛爾蘭無限公司 |
胺磺醯基吡咯醯胺衍生物及其作為用於治療b型肝炎藥物的用途
|
|
MX374532B
(es)
|
2013-06-17 |
2025-03-06 |
Broad Inst Inc |
Suministro, uso y aplicaciones terapéuticas de los sistemas y composiciones crispr-cas, para actuar sobre trastornos y enfermedades utilizando componentes víricos.
|
|
RU2716420C2
(ru)
|
2013-06-17 |
2020-03-11 |
Те Брод Инститьют Инк. |
Доставка и применение систем crispr-cas, векторов и композиций для целенаправленного воздействия и терапии в печени
|
|
CN105492611A
(zh)
|
2013-06-17 |
2016-04-13 |
布罗德研究所有限公司 |
用于序列操纵的优化的crispr-cas双切口酶系统、方法以及组合物
|
|
WO2014204724A1
(en)
|
2013-06-17 |
2014-12-24 |
The Broad Institute Inc. |
Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation
|
|
EP3725885A1
(en)
|
2013-06-17 |
2020-10-21 |
The Broad Institute, Inc. |
Functional genomics using crispr-cas systems, compositions methods, screens and applications thereof
|
|
HRP20180791T1
(hr)
|
2013-07-25 |
2018-09-07 |
Janssen Sciences Ireland Uc |
Glioksamid supstituirani derivati pirolamida i njihova uporaba kao lijekova za liječenje hepatitisa b
|
|
CA2923712C
(en)
|
2013-10-23 |
2021-11-02 |
Janssen Sciences Ireland Uc |
Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
|
JP6712948B2
(ja)
|
2013-12-12 |
2020-06-24 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
組成物、及びヌクレオチドリピート障害におけるcrispr−cas系の使用方法
|
|
JP7103750B2
(ja)
|
2013-12-12 |
2022-07-20 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
ゲノム編集のためのCRISPR-Cas系及び組成物の送達、使用及び治療適用
|
|
EP3080259B1
(en)
|
2013-12-12 |
2023-02-01 |
The Broad Institute, Inc. |
Engineering of systems, methods and optimized guide compositions with new architectures for sequence manipulation
|
|
JP6793547B2
(ja)
|
2013-12-12 |
2020-12-02 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
最適化機能CRISPR−Cas系による配列操作のための系、方法および組成物
|
|
SG10201804975PA
(en)
|
2013-12-12 |
2018-07-30 |
Broad Inst Inc |
Delivery, Use and Therapeutic Applications of the Crispr-Cas Systems and Compositions for HBV and Viral Diseases and Disorders
|
|
WO2015089364A1
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Crystal structure of a crispr-cas system, and uses thereof
|
|
US10392349B2
(en)
|
2014-01-16 |
2019-08-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
US9181288B2
(en)
|
2014-01-16 |
2015-11-10 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
US9169212B2
(en)
|
2014-01-16 |
2015-10-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
CA2936947A1
(en)
|
2014-02-05 |
2015-08-13 |
Novira Therapeutics, Inc. |
Combination therapy for treatment of hbv infections
|
|
TW201620893A
(zh)
|
2014-02-06 |
2016-06-16 |
健生科學愛爾蘭無限公司 |
磺醯胺基吡咯醯胺衍生物及其用作治療b型肝炎之醫藥品的用途
|
|
US9400280B2
(en)
|
2014-03-27 |
2016-07-26 |
Novira Therapeutics, Inc. |
Piperidine derivatives and methods of treating hepatitis B infections
|
|
WO2015193484A1
(en)
*
|
2014-06-20 |
2015-12-23 |
Drexel University |
Tagged hepadnavirus e antigen and its use in screening antiviral substances
|
|
EP3889260A1
(en)
|
2014-12-12 |
2021-10-06 |
The Broad Institute, Inc. |
Protected guide rnas (pgrnas)
|
|
CA2970370A1
(en)
|
2014-12-24 |
2016-06-30 |
Massachusetts Institute Of Technology |
Crispr having or associated with destabilization domains
|
|
JP2018510159A
(ja)
|
2015-03-19 |
2018-04-12 |
ノヴィラ・セラピューティクス・インコーポレイテッド |
アゾカン及びアゾナン誘導体及びb型肝炎感染症の治療法
|
|
US10442788B2
(en)
|
2015-04-01 |
2019-10-15 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
WO2016183266A1
(en)
|
2015-05-13 |
2016-11-17 |
Enanta Pharmaceuticals, Inc. |
Ehpatitis b antiviral agents
|
|
TWI906646B
(zh)
|
2015-06-18 |
2025-12-01 |
美商博得學院股份有限公司 |
降低脫靶效應的crispr酶突變
|
|
WO2016205759A1
(en)
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation
|
|
US10875876B2
(en)
|
2015-07-02 |
2020-12-29 |
Janssen Sciences Ireland Uc |
Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
|
|
US10179131B2
(en)
|
2015-07-13 |
2019-01-15 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
US10301255B2
(en)
|
2015-07-22 |
2019-05-28 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
WO2017015451A1
(en)
*
|
2015-07-22 |
2017-01-26 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
KR101771309B1
(ko)
*
|
2015-07-24 |
2017-08-24 |
재단법인 목암생명과학연구소 |
B형 간염 바이러스의 cccDNA 형성 억제용 약학 조성물
|
|
TW201718496A
(zh)
|
2015-09-29 |
2017-06-01 |
諾維拉治療公司 |
B型肝炎抗病毒劑之晶型
|
|
WO2017136403A1
(en)
|
2016-02-02 |
2017-08-10 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
KR102398439B1
(ko)
|
2016-03-07 |
2022-05-16 |
이난타 파마슈티칼스, 인코포레이티드 |
B형 간염 항바이러스제
|
|
AU2017248828A1
(en)
|
2016-04-15 |
2018-11-01 |
Janssen Sciences Ireland Uc |
Combinations and methods comprising a capsid assembly inhibitor
|
|
CA3028228A1
(en)
|
2016-06-10 |
2017-12-14 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
JP7158104B2
(ja)
|
2016-07-15 |
2022-10-21 |
ビラクタ セラピューティクス,インク. |
Nk細胞ベースの療法で使用するためのhdac阻害剤
|
|
MX2019006803A
(es)
|
2016-12-13 |
2019-11-18 |
Am Sciences Inc |
Composicion farmaceutica para prevenir o tratar la hepatitis b.
|
|
SG11202001685TA
(en)
|
2017-08-28 |
2020-03-30 |
Enanta Pharm Inc |
Hepatitis b antiviral agents
|
|
US20230248723A1
(en)
*
|
2017-12-04 |
2023-08-10 |
Hoffmann-La Roche Inc. |
Pyrrolo[2,3-b]pyrazine compounds as cccdna inhibitors for the treatment of hepatitis b virus (hbv) infection
|
|
WO2019113175A1
(en)
|
2017-12-06 |
2019-06-13 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
WO2019113173A1
(en)
|
2017-12-06 |
2019-06-13 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
US11058678B2
(en)
|
2018-01-22 |
2021-07-13 |
Enanta Pharmaceuticals, Inc. |
Substituted heterocycles as antiviral agents
|
|
MX2020009531A
(es)
|
2018-03-14 |
2020-10-05 |
Janssen Sciences Ireland Unlimited Co |
Regimen posologico del modulador del ensamblaje de la capside.
|
|
WO2019191166A1
(en)
|
2018-03-29 |
2019-10-03 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
WO2019240504A1
(en)
*
|
2018-06-12 |
2019-12-19 |
Am Sciences Co., Ltd. |
Modified oligonucleotides for inhibition of target gene expression
|
|
KR102273071B1
(ko)
*
|
2018-06-12 |
2021-07-05 |
주식회사 에이엠사이언스 |
B형 간염 예방 또는 치료용 조성물
|
|
JP2022500466A
(ja)
|
2018-09-21 |
2022-01-04 |
エナンタ ファーマシューティカルズ インコーポレイテッド |
抗ウイルス剤としての官能化複素環
|
|
CN112888480A
(zh)
*
|
2018-10-24 |
2021-06-01 |
豪夫迈·罗氏有限公司 |
用于治疗和预防乙型肝炎病毒疾病的新型三环化合物
|
|
IL283190B2
(en)
|
2018-11-21 |
2025-08-01 |
Enanta Pharm Inc |
Functionalized heterocycles as antiviral agents
|
|
WO2020169784A1
(en)
|
2019-02-22 |
2020-08-27 |
Janssen Sciences Ireland Unlimited Company |
Amide derivatives useful in the treatment of hbv infection or hbv-induced diseases
|
|
AR119732A1
(es)
|
2019-05-06 |
2022-01-05 |
Janssen Sciences Ireland Unlimited Co |
Derivados de amida útiles en el tratamiento de la infección por vhb o de enfermedades inducidas por vhb
|
|
AU2020283590A1
(en)
|
2019-05-31 |
2022-01-20 |
Viracta Subsidiary, Inc. |
Methods of treating virally associated cancers with histone deacetylase inhibitors
|
|
WO2020247444A1
(en)
|
2019-06-03 |
2020-12-10 |
Enanta Pharmaceuticals, Inc, |
Hepatitis b antiviral agents
|
|
WO2020247561A1
(en)
|
2019-06-04 |
2020-12-10 |
Enanta Pharmaceuticals, Inc, |
Hepatitis b antiviral agents
|
|
WO2020247575A1
(en)
|
2019-06-04 |
2020-12-10 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
US11738019B2
(en)
|
2019-07-11 |
2023-08-29 |
Enanta Pharmaceuticals, Inc. |
Substituted heterocycles as antiviral agents
|
|
US11236108B2
(en)
|
2019-09-17 |
2022-02-01 |
Enanta Pharmaceuticals, Inc. |
Functionalized heterocycles as antiviral agents
|
|
WO2021067480A1
(en)
*
|
2019-10-02 |
2021-04-08 |
University Of Washington |
Compositions and methods for treatment of hepatitis b virus infection
|
|
WO2021188414A1
(en)
|
2020-03-16 |
2021-09-23 |
Enanta Pharmaceuticals, Inc. |
Functionalized heterocyclic compounds as antiviral agents
|
|
CN116157522A
(zh)
*
|
2020-08-21 |
2023-05-23 |
豪夫迈·罗氏有限公司 |
A1cf抑制剂用于治疗乙型肝炎病毒感染的用途
|
|
CN112274516B
(zh)
*
|
2020-10-26 |
2022-08-05 |
中山大学附属第三医院 |
一种新型含碘抗病毒药物
|
|
IT202100005054A1
(it)
*
|
2021-03-04 |
2022-09-04 |
Azienda Ospedaliero Univ Di Parma |
Composto farmaceutico per l’uso in un trattamento terapeutico dell’infezione cronica da hbv e metodo per l’identificazione di linfociti esauriti
|