AU2013267209B2 - Modulation of hepatitis B virus cccDNA transcription - Google Patents
Modulation of hepatitis B virus cccDNA transcription Download PDFInfo
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- AU2013267209B2 AU2013267209B2 AU2013267209A AU2013267209A AU2013267209B2 AU 2013267209 B2 AU2013267209 B2 AU 2013267209B2 AU 2013267209 A AU2013267209 A AU 2013267209A AU 2013267209 A AU2013267209 A AU 2013267209A AU 2013267209 B2 AU2013267209 B2 AU 2013267209B2
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- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/US2013/043691 WO2013181584A2 (en) | 2012-06-01 | 2013-05-31 | Modulation of hepatitis b virus cccdna transcription |
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| EP (1) | EP2854832A4 (https=) |
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| KR102271574B1 (ko) | 2012-08-28 | 2021-07-01 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 설파모일-아릴아미드 및 b형 간염 치료제로서의 그 용도 |
| HK1215030A1 (zh) * | 2012-11-09 | 2016-08-12 | Indiana University Research And Technology Corporation | 用於hbv組裝效應劑的替代用途 |
| EP3031921B1 (en) | 2012-12-12 | 2025-03-12 | The Broad Institute, Inc. | Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications |
| EP2931899A1 (en) | 2012-12-12 | 2015-10-21 | The Broad Institute, Inc. | Functional genomics using crispr-cas systems, compositions, methods, knock out libraries and applications thereof |
| WO2014093709A1 (en) | 2012-12-12 | 2014-06-19 | The Broad Institute, Inc. | Methods, models, systems, and apparatus for identifying target sequences for cas enzymes or crispr-cas systems for target sequences and conveying results thereof |
| WO2014131847A1 (en) | 2013-02-28 | 2014-09-04 | Janssen R&D Ireland | Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis b |
| US8993771B2 (en) | 2013-03-12 | 2015-03-31 | Novira Therapeutics, Inc. | Hepatitis B antiviral agents |
| MX353412B (es) | 2013-04-03 | 2018-01-10 | Janssen Sciences Ireland Uc | Derivados de n-fenil-carboxamida y su uso como medicamentos para el tratamiento de la hepatitis b. |
| TWI733288B (zh) | 2013-05-17 | 2021-07-11 | 愛爾蘭商健生科學愛爾蘭無限公司 | 胺磺醯基吡咯醯胺衍生物及其作為用於治療ｂ型肝炎藥物的用途 |
| MX374532B (es) | 2013-06-17 | 2025-03-06 | Broad Inst Inc | Suministro, uso y aplicaciones terapéuticas de los sistemas y composiciones crispr-cas, para actuar sobre trastornos y enfermedades utilizando componentes víricos. |
| RU2716420C2 (ru) | 2013-06-17 | 2020-03-11 | Те Брод Инститьют Инк. | Доставка и применение систем crispr-cas, векторов и композиций для целенаправленного воздействия и терапии в печени |
| CN105492611A (zh) | 2013-06-17 | 2016-04-13 | 布罗德研究所有限公司 | 用于序列操纵的优化的crispr-cas双切口酶系统、方法以及组合物 |
| WO2014204724A1 (en) | 2013-06-17 | 2014-12-24 | The Broad Institute Inc. | Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation |
| EP3725885A1 (en) | 2013-06-17 | 2020-10-21 | The Broad Institute, Inc. | Functional genomics using crispr-cas systems, compositions methods, screens and applications thereof |
| HRP20180791T1 (hr) | 2013-07-25 | 2018-09-07 | Janssen Sciences Ireland Uc | Glioksamid supstituirani derivati pirolamida i njihova uporaba kao lijekova za liječenje hepatitisa b |
| CA2923712C (en) | 2013-10-23 | 2021-11-02 | Janssen Sciences Ireland Uc | Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b |
| JP6712948B2 (ja) | 2013-12-12 | 2020-06-24 | ザ・ブロード・インスティテュート・インコーポレイテッド | 組成物、及びヌクレオチドリピート障害におけるｃｒｉｓｐｒ−ｃａｓ系の使用方法 |
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Also Published As
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| PH12014502659A1 (en) | 2015-01-21 |
| EP2854832A2 (en) | 2015-04-08 |
| CN104507488A (zh) | 2015-04-08 |
| EP2854832A4 (en) | 2016-06-08 |
| IL235912A0 (en) | 2015-01-29 |
| JP6431478B2 (ja) | 2018-11-28 |
| SG11201407970VA (en) | 2014-12-30 |
| AU2017202675A1 (en) | 2017-05-11 |
| JP2015518055A (ja) | 2015-06-25 |
| KR20150022911A (ko) | 2015-03-04 |
| WO2013181584A3 (en) | 2014-02-13 |
| HK1208823A1 (en) | 2016-03-18 |
| AU2013267209A1 (en) | 2014-12-18 |
| US10143720B2 (en) | 2018-12-04 |
| US20180369323A1 (en) | 2018-12-27 |
| BR112014029697A2 (pt) | 2017-08-08 |
| US20150265672A1 (en) | 2015-09-24 |
| US20170296619A1 (en) | 2017-10-19 |
| CA2874828A1 (en) | 2013-12-05 |
| WO2013181584A2 (en) | 2013-12-05 |
| US9623071B2 (en) | 2017-04-18 |
| KR101945578B1 (ko) | 2019-02-07 |
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