JP2021530488A5 - - Google Patents

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Publication number
JP2021530488A5
JP2021530488A5 JP2021500613A JP2021500613A JP2021530488A5 JP 2021530488 A5 JP2021530488 A5 JP 2021530488A5 JP 2021500613 A JP2021500613 A JP 2021500613A JP 2021500613 A JP2021500613 A JP 2021500613A JP 2021530488 A5 JP2021530488 A5 JP 2021530488A5
Authority
JP
Japan
Prior art keywords
alkyl
heterocyclyl
pharmaceutical composition
formula
composition according
Prior art date
Application number
JP2021500613A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021530488A (ja
JPWO2020011804A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2019/068448 external-priority patent/WO2020011804A1/en
Publication of JP2021530488A publication Critical patent/JP2021530488A/ja
Publication of JP2021530488A5 publication Critical patent/JP2021530488A5/ja
Publication of JPWO2020011804A5 publication Critical patent/JPWO2020011804A5/ja
Priority to JP2024052193A priority Critical patent/JP2024095711A/ja
Pending legal-status Critical Current

Links

JP2021500613A 2018-07-12 2019-07-09 可溶性グアニル酸シクラーゼ活性化薬としてのアルコキシピラゾール Pending JP2021530488A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024052193A JP2024095711A (ja) 2018-07-12 2024-03-27 可溶性グアニル酸シクラーゼ活性化薬としてのアルコキシピラゾール

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862696887P 2018-07-12 2018-07-12
US62/696,887 2018-07-12
PCT/EP2019/068448 WO2020011804A1 (en) 2018-07-12 2019-07-09 Alkoxy pyrazoles as soluble guanylate cyclase activators

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024052193A Division JP2024095711A (ja) 2018-07-12 2024-03-27 可溶性グアニル酸シクラーゼ活性化薬としてのアルコキシピラゾール

Publications (3)

Publication Number Publication Date
JP2021530488A JP2021530488A (ja) 2021-11-11
JP2021530488A5 true JP2021530488A5 (https=) 2022-07-15
JPWO2020011804A5 JPWO2020011804A5 (https=) 2022-07-15

Family

ID=67314737

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021500613A Pending JP2021530488A (ja) 2018-07-12 2019-07-09 可溶性グアニル酸シクラーゼ活性化薬としてのアルコキシピラゾール
JP2024052193A Pending JP2024095711A (ja) 2018-07-12 2024-03-27 可溶性グアニル酸シクラーゼ活性化薬としてのアルコキシピラゾール

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024052193A Pending JP2024095711A (ja) 2018-07-12 2024-03-27 可溶性グアニル酸シクラーゼ活性化薬としてのアルコキシピラゾール

Country Status (14)

Country Link
US (1) US11690848B2 (https=)
EP (1) EP3820470B1 (https=)
JP (2) JP2021530488A (https=)
KR (1) KR20210032443A (https=)
CN (1) CN112384214A (https=)
AU (1) AU2019301887A1 (https=)
BR (1) BR112020025670A2 (https=)
CA (1) CA3103727A1 (https=)
CL (1) CL2021000023A1 (https=)
EA (1) EA202190193A1 (https=)
MA (1) MA53118A (https=)
MX (1) MX2021000405A (https=)
PH (1) PH12021550075A1 (https=)
WO (1) WO2020011804A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118900690A (zh) * 2022-03-21 2024-11-05 勃林格殷格翰国际有限公司 用于治疗门脉高压的可溶性鸟苷酸环化酶活化剂
WO2024097316A1 (en) 2022-11-04 2024-05-10 Boehringer Ingelheim International Gmbh Soluble guanylate cyclase activators for treating systemic sclerosis
US20240199590A1 (en) 2022-12-09 2024-06-20 Boehringer Ingelheim International Gmbh Solid forms of a sgc activator
WO2025036839A1 (en) * 2023-08-16 2025-02-20 Boehringer Ingelheim International Gmbh Soluble guanylate cyclase activators for treating clinically significant portal hypertension and decompensated cirrhosis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2748798T3 (es) 2012-09-07 2020-03-18 Boehringer Ingelheim Int Alcoxi pirazoles como activadores de la guanilato ciclasa soluble
BR112018015718A2 (pt) * 2016-02-01 2019-01-08 Ironwood Pharmaceuticals Inc utilização de estimuladores de sgc para o tratamento de esteato-hepatite não alcoólica (nash)
US10925876B2 (en) 2016-05-18 2021-02-23 Merck Sharp & Dohme Corp. Methods for using triazolo-pyrazinyl soluble guanylate cyclase activators in fibrotic disorders

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