JP2021529172A5 - - Google Patents
Info
- Publication number
- JP2021529172A5 JP2021529172A5 JP2020570902A JP2020570902A JP2021529172A5 JP 2021529172 A5 JP2021529172 A5 JP 2021529172A5 JP 2020570902 A JP2020570902 A JP 2020570902A JP 2020570902 A JP2020570902 A JP 2020570902A JP 2021529172 A5 JP2021529172 A5 JP 2021529172A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- prodrug
- alkyl
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862688225P | 2018-06-21 | 2018-06-21 | |
| US62/688,225 | 2018-06-21 | ||
| US201962827505P | 2019-04-01 | 2019-04-01 | |
| US62/827,505 | 2019-04-01 | ||
| PCT/US2019/038245 WO2019246403A1 (en) | 2018-06-21 | 2019-06-20 | Ectonucleotidase inhibitors and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021529172A JP2021529172A (ja) | 2021-10-28 |
| JP2021529172A5 true JP2021529172A5 (enExample) | 2022-05-16 |
| JP7538047B2 JP7538047B2 (ja) | 2024-08-21 |
Family
ID=68981317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020570902A Active JP7538047B2 (ja) | 2018-06-21 | 2019-06-20 | エクトヌクレオチダーゼ阻害剤及びその使用方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US11078228B2 (enExample) |
| EP (1) | EP3810617A4 (enExample) |
| JP (1) | JP7538047B2 (enExample) |
| KR (1) | KR102902754B1 (enExample) |
| CN (1) | CN112888696B (enExample) |
| AU (1) | AU2019288495B2 (enExample) |
| BR (1) | BR112020025132B1 (enExample) |
| CA (1) | CA3104088A1 (enExample) |
| CL (1) | CL2020003339A1 (enExample) |
| CO (1) | CO2021000049A2 (enExample) |
| IL (1) | IL279475B2 (enExample) |
| MX (1) | MX2020013320A (enExample) |
| PH (1) | PH12020552214A1 (enExample) |
| SG (1) | SG11202012001YA (enExample) |
| TW (1) | TWI911140B (enExample) |
| WO (1) | WO2019246403A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102638592B1 (ko) | 2016-12-22 | 2024-02-19 | 안텐진 테라퓨틱스 리미티드 | 엑토뉴클레오티다제 억제제 및 이의 용도 |
| US11129841B2 (en) | 2017-05-10 | 2021-09-28 | Oric Pharmaceuticals, Inc. | CD73 inhibitors |
| US11377469B2 (en) | 2017-11-03 | 2022-07-05 | Oric Pharmaceuticals, Inc. | CD73 inhibitors |
| CA3098493A1 (en) | 2018-04-30 | 2019-11-07 | Oric Pharmaceuticals, Inc. | Cd73 inhibitors |
| KR102902754B1 (ko) * | 2018-06-21 | 2025-12-19 | 안텐진 테라퓨틱스 리미티드 | 엑토뉴클레오티다제 저해제 및 이의 사용 방법 |
| TWI821559B (zh) * | 2019-04-28 | 2023-11-11 | 大陸商上海和譽生物醫藥科技有限公司 | 一種cd73抑制劑，其製備方法和應用 |
| CA3143496A1 (en) * | 2019-06-20 | 2020-12-24 | Antengene Therapeutics Limited | Ectonucleotidase inhibitors and methods of use thereof |
| US12544391B2 (en) | 2019-07-16 | 2026-02-10 | Oric Pharmaceuticals, Inc. | CD73 inhibitors |
| CN116854758A (zh) | 2019-10-30 | 2023-10-10 | 欧瑞克制药公司 | Cd73抑制剂 |
| AU2023252914A1 (en) | 2022-04-13 | 2024-10-17 | Arcus Biosciences, Inc. | Combination therapy for treating trop-2 expressing cancers |
| CN116375772B (zh) * | 2023-02-13 | 2024-11-01 | 北京先通国际医药科技股份有限公司 | 腺苷的制备方法及其用途 |
| US20250230168A1 (en) | 2023-12-22 | 2025-07-17 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992019638A1 (en) | 1991-04-24 | 1992-11-12 | Yamasa Shoyu Kabushiki Kaisha | 1-β-D-ARABINOFURANOSYL-(E)-5-(2-HALOGENOVINYL)-URACIL DERIVATIVE |
| WO1994010128A1 (en) | 1992-11-02 | 1994-05-11 | Affymax Technologies N.V. | Novel photoreactive protecting groups |
| US5635608A (en) | 1994-11-08 | 1997-06-03 | Molecular Probes, Inc. | α-carboxy caged compounds |
| TW528755B (en) | 1996-12-24 | 2003-04-21 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
| NL1005244C2 (nl) | 1997-02-10 | 1998-08-18 | Inst Voor Agrotech Onderzoek | Oppervlakte-actieve aminen en glycosiden. |
| WO2004096233A2 (en) | 2003-04-25 | 2004-11-11 | Gilead Sciences, Inc. | Nucleoside phosphonate conjugates |
| EP1860113A1 (en) | 2006-05-24 | 2007-11-28 | Rheinische Friedrich-Wilhelms-Universität Bonn | Ectonucleotidase inhibitors |
| EP2040712B1 (en) * | 2006-07-18 | 2011-03-02 | Anadys Pharmaceuticals, Inc. | Carbonate and carbamate prodrugs of thiazolo [4,5-d] pyrimidines |
| WO2009061781A1 (en) | 2007-11-07 | 2009-05-14 | Schering Corporation | Novel modulators of cell cycle checkpoints and their use in combination with checkpoint kinase inhibitors |
| EP2070938A1 (en) * | 2007-12-13 | 2009-06-17 | Heidelberg Pharma AG | Clofarabine dietherphospholipid derivatives |
| CA2684017A1 (en) | 2009-10-22 | 2011-04-22 | Universite Laval | Ectonucleotidase pyrophosphate/phosphodiesterase-1 (enpp-1) as a target for the treatment of aortic valve stenosis and cardiovascular calcification |
| US9725479B2 (en) | 2010-04-22 | 2017-08-08 | Ionis Pharmaceuticals, Inc. | 5′-end derivatives |
| CN103209970B (zh) | 2010-07-08 | 2016-08-24 | 生命科技公司 | 原位化学发光底物和测定 |
| CN102311472B (zh) | 2010-07-09 | 2014-09-03 | 神隆(昆山)生化科技有限公司 | 2-氯-9-(2’-脱氧-2’-氟-β-D-阿拉伯呋喃糖基)-腺嘌呤的制备 |
| KR101960113B1 (ko) | 2011-05-03 | 2019-03-19 | 라이프 테크놀로지스 코포레이션 | 섬광 및 백열광 １,２-디옥세탄들 |
| EP3517539B1 (en) * | 2011-07-15 | 2022-12-14 | Boehringer Ingelheim International GmbH | Substituted dimeric quinazoline derivative, its preparation and its use in pharmaceutical compositions for the treatment of type i and ii diabetes |
| GB201220843D0 (en) | 2012-11-20 | 2013-01-02 | Univ College Cork Nat Univ Ie | Compound |
| CN106463125B (zh) * | 2014-04-25 | 2020-09-15 | 杜比实验室特许公司 | 基于空间元数据的音频分割 |
| EP3134411B1 (en) | 2014-04-25 | 2021-06-30 | Boehringer Ingelheim International GmbH | Purine derivatives as cd73 inhibitors for the treatment of cancer |
| WO2017066782A1 (en) | 2015-10-16 | 2017-04-20 | Modernatx, Inc. | Hydrophobic mrna cap analogs |
| DK3362461T3 (da) | 2015-10-16 | 2022-05-09 | Modernatx Inc | Mrna-cap-analoger med modificeret phosphatbinding |
| WO2017066791A1 (en) | 2015-10-16 | 2017-04-20 | Modernatx, Inc. | Sugar substituted mrna cap analogs |
| US10611790B2 (en) | 2015-11-02 | 2020-04-07 | Mitobridge, Inc. | Nicotinamide riboside and nicotinamide mononucleotide derivatives for use in the treatments of mitochondrial-related diseases |
| JP6411676B2 (ja) * | 2015-12-03 | 2018-10-24 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ | Ｓｔｉｎｇの調節因子としての環状プリンジヌクレオチド |
| CN110234656B (zh) | 2016-09-09 | 2023-02-28 | 卡利泰拉生物科技公司 | 外核苷酸酶抑制剂及其使用方法 |
| KR102638592B1 (ko) | 2016-12-22 | 2024-02-19 | 안텐진 테라퓨틱스 리미티드 | 엑토뉴클레오티다제 억제제 및 이의 용도 |
| US10794113B2 (en) * | 2016-12-22 | 2020-10-06 | Marketing Displays, Inc. | Compact privacy screen |
| WO2018208727A1 (en) * | 2017-05-08 | 2018-11-15 | Eternity Bioscience Inc. | Nucleoside and nucleotide analogues as cd73 inhibitors and therapeutic uses thereof |
| US11129841B2 (en) * | 2017-05-10 | 2021-09-28 | Oric Pharmaceuticals, Inc. | CD73 inhibitors |
| CN109503587B (zh) * | 2017-09-14 | 2022-01-11 | 辽宁利锋科技开发有限公司 | 双杂环三氮唑核苷类似物的抗肿瘤作用与应用 |
| US11377469B2 (en) * | 2017-11-03 | 2022-07-05 | Oric Pharmaceuticals, Inc. | CD73 inhibitors |
| CA3098493A1 (en) * | 2018-04-30 | 2019-11-07 | Oric Pharmaceuticals, Inc. | Cd73 inhibitors |
| TW202017569A (zh) * | 2018-05-31 | 2020-05-16 | 美商佩樂敦治療公司 | 用於抑制cd73之組合物及方法 |
| KR102902754B1 (ko) | 2018-06-21 | 2025-12-19 | 안텐진 테라퓨틱스 리미티드 | 엑토뉴클레오티다제 저해제 및 이의 사용 방법 |
| CA3143496A1 (en) | 2019-06-20 | 2020-12-24 | Antengene Therapeutics Limited | Ectonucleotidase inhibitors and methods of use thereof |
-
2019
- 2019-06-20 KR KR1020217001701A patent/KR102902754B1/ko active Active
- 2019-06-20 WO PCT/US2019/038245 patent/WO2019246403A1/en not_active Ceased
- 2019-06-20 JP JP2020570902A patent/JP7538047B2/ja active Active
- 2019-06-20 CA CA3104088A patent/CA3104088A1/en active Pending
- 2019-06-20 US US16/447,159 patent/US11078228B2/en active Active
- 2019-06-20 MX MX2020013320A patent/MX2020013320A/es unknown
- 2019-06-20 CN CN201980054369.1A patent/CN112888696B/zh active Active
- 2019-06-20 IL IL279475A patent/IL279475B2/en unknown
- 2019-06-20 BR BR112020025132-1A patent/BR112020025132B1/pt active IP Right Grant
- 2019-06-20 EP EP19823042.7A patent/EP3810617A4/en active Pending
- 2019-06-20 SG SG11202012001YA patent/SG11202012001YA/en unknown
- 2019-06-20 AU AU2019288495A patent/AU2019288495B2/en active Active
- 2019-06-21 TW TW108121817A patent/TWI911140B/zh active
-
2020
- 2020-12-18 PH PH12020552214A patent/PH12020552214A1/en unknown
- 2020-12-21 CL CL2020003339A patent/CL2020003339A1/es unknown
-
2021
- 2021-01-06 CO CONC2021/0000049A patent/CO2021000049A2/es unknown
- 2021-06-28 US US17/359,990 patent/US11858957B2/en active Active
-
2023
- 2023-11-01 US US18/499,248 patent/US12421273B2/en active Active
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