JP2021528447A5 - - Google Patents
Info
- Publication number
- JP2021528447A5 JP2021528447A5 JP2020571700A JP2020571700A JP2021528447A5 JP 2021528447 A5 JP2021528447 A5 JP 2021528447A5 JP 2020571700 A JP2020571700 A JP 2020571700A JP 2020571700 A JP2020571700 A JP 2020571700A JP 2021528447 A5 JP2021528447 A5 JP 2021528447A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- oxadiazole
- azabicyclo
- octan
- diazaspiro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023158190A JP2023164721A (ja) | 2018-06-22 | 2023-09-22 | ムスカリンｍ１および／またはｍ４受容体のアゴニストとしてのオキサジアゾール |
| JP2025174614A JP2026002915A (ja) | 2018-06-22 | 2025-10-16 | ムスカリンｍ１および／またはｍ４受容体のアゴニストとしてのオキサジアゾール |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1810245.9 | 2018-06-22 | ||
| GBGB1810245.9A GB201810245D0 (en) | 2018-06-22 | 2018-06-22 | Pharmaceutical compounds |
| PCT/GB2019/051778 WO2019243850A1 (en) | 2018-06-22 | 2019-06-24 | Oxadiazoles as agonists of the muscarinic m1 and/or m4 receptor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023158190A Division JP2023164721A (ja) | 2018-06-22 | 2023-09-22 | ムスカリンｍ１および／またはｍ４受容体のアゴニストとしてのオキサジアゾール |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021528447A JP2021528447A (ja) | 2021-10-21 |
| JP2021528447A5 true JP2021528447A5 (enExample) | 2022-07-01 |
| JP7389762B2 JP7389762B2 (ja) | 2023-11-30 |
Family
ID=63042556
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020571700A Active JP7389762B2 (ja) | 2018-06-22 | 2019-06-24 | ムスカリンｍ１および／またはｍ４受容体のアゴニストとしてのオキサジアゾール |
| JP2023158190A Withdrawn JP2023164721A (ja) | 2018-06-22 | 2023-09-22 | ムスカリンｍ１および／またはｍ４受容体のアゴニストとしてのオキサジアゾール |
| JP2025174614A Pending JP2026002915A (ja) | 2018-06-22 | 2025-10-16 | ムスカリンｍ１および／またはｍ４受容体のアゴニストとしてのオキサジアゾール |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023158190A Withdrawn JP2023164721A (ja) | 2018-06-22 | 2023-09-22 | ムスカリンｍ１および／またはｍ４受容体のアゴニストとしてのオキサジアゾール |
| JP2025174614A Pending JP2026002915A (ja) | 2018-06-22 | 2025-10-16 | ムスカリンｍ１および／またはｍ４受容体のアゴニストとしてのオキサジアゾール |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10858352B2 (enExample) |
| EP (1) | EP3810607A1 (enExample) |
| JP (3) | JP7389762B2 (enExample) |
| KR (1) | KR102833588B1 (enExample) |
| CN (2) | CN119039284A (enExample) |
| AU (1) | AU2019289216B2 (enExample) |
| BR (1) | BR112020026437A2 (enExample) |
| CA (1) | CA3104085A1 (enExample) |
| GB (1) | GB201810245D0 (enExample) |
| MX (1) | MX2020014156A (enExample) |
| SG (1) | SG11202012570TA (enExample) |
| TW (1) | TWI872024B (enExample) |
| WO (1) | WO2019243850A1 (enExample) |
| ZA (1) | ZA202007986B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2619829T3 (es) | 2011-11-18 | 2017-06-27 | Heptares Therapeutics Limited | Agonistas del receptor muscarínico M1 |
| GB201404922D0 (en) | 2014-03-19 | 2014-04-30 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
| GB201513743D0 (en) | 2015-08-03 | 2015-09-16 | Heptares Therapeutics Ltd | Muscarinic agonists |
| GB201519352D0 (en) | 2015-11-02 | 2015-12-16 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
| GB201617454D0 (en) | 2016-10-14 | 2016-11-30 | Heptares Therapeutics Limited | Pharmaceutical compounds |
| GB201810245D0 (en) | 2018-06-22 | 2018-08-08 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
| GB201810239D0 (en) | 2018-06-22 | 2018-08-08 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
| GB201819961D0 (en) | 2018-12-07 | 2019-01-23 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
| GB201819960D0 (en) | 2018-12-07 | 2019-01-23 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
| GB202020191D0 (en) * | 2020-12-18 | 2021-02-03 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
| PH12022550860A1 (en) | 2019-10-09 | 2023-06-14 | Novartis Ag | 5-oxa-2-azaspiro[3.4]octane derivatives as m4 agonists |
| UY38906A (es) | 2019-10-09 | 2021-05-31 | Novartis Ag | Compuestos 2- derivados de azaspiro[3,4]octano como agonistas de m4 y composiciones de los mismos |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2307899A (en) * | 1997-12-23 | 1999-07-12 | Alcon Laboratories, Inc. | Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions |
| US7786141B2 (en) | 2004-08-19 | 2010-08-31 | Vertex Pharmaceuticals Incorporated | Dihydrospiroindene modulators of muscarinic receptors |
| CA2634456A1 (en) | 2005-12-22 | 2007-07-05 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
| RU2008137583A (ru) | 2006-02-22 | 2010-03-27 | Вертекс Фармасьютикалз Инкорпорейшн (Us) | Спиропиперидины в качестве модуляторов мускариновых рецепторов |
| CN101553231A (zh) | 2006-08-15 | 2009-10-07 | 弗特克斯药品有限公司 | 毒蕈碱受体调节剂 |
| WO2008117229A1 (en) * | 2007-03-23 | 2008-10-02 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
| CN103221046A (zh) * | 2010-09-17 | 2013-07-24 | 阵列生物制药公司 | 作为gpr119调节剂的哌啶基取代的内酰胺 |
| EP2897948B1 (en) * | 2012-09-18 | 2016-08-31 | Heptares Therapeutics Limited | Bicyclic aza compounds as muscarinic m1 receptor agonists |
| US9593106B2 (en) * | 2013-02-07 | 2017-03-14 | Heptares Therapeutics Limited | Piperidin-1-yl and azepin-1-yl carboxylates as muscarinic M4 receptor agonists |
| RU2685230C2 (ru) * | 2014-02-06 | 2019-04-17 | Хептарес Терапьютикс Лимитед | Бициклические азотсодержащие соединения как агонисты М1 мускариновых рецепторов |
| GB201404922D0 (en) * | 2014-03-19 | 2014-04-30 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
| GB201513743D0 (en) * | 2015-08-03 | 2015-09-16 | Heptares Therapeutics Ltd | Muscarinic agonists |
| GB201513742D0 (en) * | 2015-08-03 | 2015-09-16 | Heptares Therapeutics Ltd | Muscarinic agonists |
| GB201617454D0 (en) * | 2016-10-14 | 2016-11-30 | Heptares Therapeutics Limited | Pharmaceutical compounds |
| GB201810245D0 (en) * | 2018-06-22 | 2018-08-08 | Heptares Therapeutics Ltd | Pharmaceutical compounds |
-
2018
- 2018-06-22 GB GBGB1810245.9A patent/GB201810245D0/en not_active Ceased
-
2019
- 2019-06-24 BR BR112020026437-7A patent/BR112020026437A2/pt unknown
- 2019-06-24 KR KR1020217001748A patent/KR102833588B1/ko active Active
- 2019-06-24 SG SG11202012570TA patent/SG11202012570TA/en unknown
- 2019-06-24 CN CN202410873092.8A patent/CN119039284A/zh active Pending
- 2019-06-24 CA CA3104085A patent/CA3104085A1/en active Pending
- 2019-06-24 AU AU2019289216A patent/AU2019289216B2/en active Active
- 2019-06-24 US US16/450,279 patent/US10858352B2/en active Active
- 2019-06-24 MX MX2020014156A patent/MX2020014156A/es unknown
- 2019-06-24 CN CN201980054880.1A patent/CN112585135B/zh active Active
- 2019-06-24 TW TW108122031A patent/TWI872024B/zh active
- 2019-06-24 WO PCT/GB2019/051778 patent/WO2019243850A1/en not_active Ceased
- 2019-06-24 JP JP2020571700A patent/JP7389762B2/ja active Active
- 2019-06-24 EP EP19734158.9A patent/EP3810607A1/en active Pending
-
2020
- 2020-10-13 US US17/069,070 patent/US11319312B2/en active Active
- 2020-12-21 ZA ZA2020/07986A patent/ZA202007986B/en unknown
-
2023
- 2023-09-22 JP JP2023158190A patent/JP2023164721A/ja not_active Withdrawn
-
2025
- 2025-10-16 JP JP2025174614A patent/JP2026002915A/ja active Pending
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