JP2021527092A5 - - Google Patents

Info

Publication number
JP2021527092A5
JP2021527092A5 JP2020569024A JP2020569024A JP2021527092A5 JP 2021527092 A5 JP2021527092 A5 JP 2021527092A5 JP 2020569024 A JP2020569024 A JP 2020569024A JP 2020569024 A JP2020569024 A JP 2020569024A JP 2021527092 A5 JP2021527092 A5 JP 2021527092A5
Authority
JP
Japan
Prior art keywords
compound
subject
item
weeks
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020569024A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021527092A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/036848 external-priority patent/WO2019241442A1/en
Publication of JP2021527092A publication Critical patent/JP2021527092A/ja
Publication of JP2021527092A5 publication Critical patent/JP2021527092A5/ja
Priority to JP2023205211A priority Critical patent/JP2024028849A/ja
Priority to JP2025064902A priority patent/JP2025108553A/ja
Pending legal-status Critical Current

Links

JP2020569024A 2018-06-12 2019-06-12 19−ノルc3,3−二置換c21−n−ピラゾリルステロイドおよびその使用方法 Pending JP2021527092A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023205211A JP2024028849A (ja) 2018-06-12 2023-12-05 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法
JP2025064902A JP2025108553A (ja) 2018-06-12 2025-04-10 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862684155P 2018-06-12 2018-06-12
US62/684,155 2018-06-12
US201962789329P 2019-01-07 2019-01-07
US62/789,329 2019-01-07
US201962841645P 2019-05-01 2019-05-01
US62/841,645 2019-05-01
PCT/US2019/036848 WO2019241442A1 (en) 2018-06-12 2019-06-12 A 19-nor c3,3-disubstituted c21 -n-pyrazolyl steroid and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023205211A Division JP2024028849A (ja) 2018-06-12 2023-12-05 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法

Publications (2)

Publication Number Publication Date
JP2021527092A JP2021527092A (ja) 2021-10-11
JP2021527092A5 true JP2021527092A5 (https=) 2022-06-16

Family

ID=67211854

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020569024A Pending JP2021527092A (ja) 2018-06-12 2019-06-12 19−ノルc3,3−二置換c21−n−ピラゾリルステロイドおよびその使用方法
JP2023205211A Pending JP2024028849A (ja) 2018-06-12 2023-12-05 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法
JP2025064902A Pending JP2025108553A (ja) 2018-06-12 2025-04-10 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023205211A Pending JP2024028849A (ja) 2018-06-12 2023-12-05 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法
JP2025064902A Pending JP2025108553A (ja) 2018-06-12 2025-04-10 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法

Country Status (12)

Country Link
US (4) US20210338692A1 (https=)
EP (1) EP3806863A1 (https=)
JP (3) JP2021527092A (https=)
KR (1) KR20210021005A (https=)
CN (2) CN112533611A (https=)
AU (2) AU2019287491B2 (https=)
CA (1) CA3103421A1 (https=)
IL (1) IL279315A (https=)
MA (1) MA52894A (https=)
MX (2) MX2020013557A (https=)
SG (1) SG11202012344RA (https=)
WO (1) WO2019241442A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2806877B2 (en) 2012-01-23 2025-01-29 Sage Therapeutics, Inc. Neuroactive steroid formulations comprising a complex of allopregnanolone and sulfobutyl ether beta-cyclodextrin
CA2882708A1 (en) 2012-08-21 2014-02-27 Sage Therapeutics, Inc. Methods of treating epilepsy or status epilepticus
KR102396328B1 (ko) 2013-04-17 2022-05-10 세이지 테라퓨틱스, 인크. 19-노르 c3,3-이치환된 c21-n-피라졸릴 스테로이드 및 그의 사용 방법
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
JOP20200195A1 (ar) 2014-09-08 2017-06-16 Sage Therapeutics Inc سترويدات وتركيبات نشطة عصبياً، واستخداماتها
WO2016082789A1 (en) 2014-11-27 2016-06-02 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
EP3504189A1 (en) 2016-08-23 2019-07-03 Sage Therapeutics, Inc. A crystalline 19-nor c3, 3-disubstituted c21-n-pyrazolyl steroid
MA51046A (fr) 2017-12-08 2021-03-17 Sage Therapeutics Inc Dérivés de 21-[4-cyano-pyrazol-1-yl]-19-nor-pregan-3. alpha-ol-20-one deutérés pour le traitement de troubles du snc
KR20220112803A (ko) * 2019-12-05 2022-08-11 세이지 테라퓨틱스, 인크. 19-nor c3,3-이치환된 c21-n-피라졸릴 스테로이드 및 그의 사용 방법
EP4125921A1 (en) 2020-03-25 2023-02-08 Sage Therapeutics, Inc. Use of agents for treatment of respiratory conditions
KR20230041049A (ko) * 2020-07-20 2023-03-23 세이지 테라퓨틱스, 인크. 19-노르 c3,3-이치환된 c21-n-피라졸릴 스테로이드의 제형 및 이의 사용 방법
KR20230136599A (ko) * 2021-01-28 2023-09-26 세이지 테라퓨틱스, 인크. 성 기능장애의 치료를 위한 신경활성 스테로이드의용도
US20240245711A1 (en) * 2021-03-17 2024-07-25 Sage Therapeutics, Inc. A 19-nor c3,3-disubstituted c21-n-pyrazolyl steroid for the treatment of major depressive disorder
WO2022232504A1 (en) * 2021-04-29 2022-11-03 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21 -n-pyrazolyl steroid for use in treating major depressive disorder and postpartum depression
EP4329769A1 (en) * 2021-04-29 2024-03-06 Sage Therapeutics, Inc. Neuroactive steroid for use in treating major depressive disorder and postpartum depression in a lactating female
IL315023A (en) * 2022-02-16 2024-10-01 Sage Therapeutics Inc Neuroactive steroids for treatment of cns-related disorders
WO2025175214A1 (en) * 2024-02-16 2025-08-21 Engrail Therapeutics, Inc. Methods of treating generalized anxiety disorder

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102396328B1 (ko) * 2013-04-17 2022-05-10 세이지 테라퓨틱스, 인크. 19-노르 c3,3-이치환된 c21-n-피라졸릴 스테로이드 및 그의 사용 방법
JOP20200195A1 (ar) * 2014-09-08 2017-06-16 Sage Therapeutics Inc سترويدات وتركيبات نشطة عصبياً، واستخداماتها
ME03809B (me) * 2014-10-16 2021-04-20 Sage Therapeutics Inc KOMPOZICIJE I POSTUPCI ZA LEČENJE POREMEĆAJA CNS-a
KR20240157128A (ko) * 2016-03-08 2024-10-31 세이지 테라퓨틱스, 인크. 신경활성 스테로이드, 조성물, 및 그의 용도
EP3504189A1 (en) * 2016-08-23 2019-07-03 Sage Therapeutics, Inc. A crystalline 19-nor c3, 3-disubstituted c21-n-pyrazolyl steroid
WO2019051264A1 (en) * 2017-09-07 2019-03-14 Sage Therapeutics, Inc. NEUROACTIVE STEROIDS AND METHODS OF USE

Similar Documents

Publication Publication Date Title
JP2021527092A5 (https=)
JP2022537551A5 (https=)
JP2016517434A5 (https=)
JP2018507243A5 (https=)
JP2021152060A (ja) アカンプロセートおよびd−サイクロセリンを使用する組み合わせ療法
JP2016507500A5 (https=)
JP2022554276A5 (https=)
JP2021509395A5 (https=)
JP2022521233A5 (https=)
JP2016505050A5 (https=)
WO2002078691A1 (en) Duloxetine for treatment of hot flashes
JP2023011549A5 (https=)
WO2023280238A1 (zh) 一种包含绿原酸的药物组合物在制备治疗早期阿尔茨海默病的药物中的用途
JP2021530568A5 (https=)
JP2022504435A5 (https=)
JP2012031141A (ja) 骨髄異形性症候群を治療するための組成物および方法
US20040152733A1 (en) Duloxetine for treatment of hot flashes
JP2024531799A5 (https=)
KR102615988B1 (ko) 항-n-메틸-d-아스파르테이트 수용체(anti-n-methyl-d-aspartate receptor) 뇌염 예방 또는 치료에 사용하기 위한 벤조산 또는 이의 염 및 유도체
JP2025505261A5 (https=)
CN104906501A (zh) 治疗银屑病的中药组分组合物
JP2023518430A (ja) 感染症の治療におけるブシラミンの使用
US20110301199A1 (en) Compositions and methods for treating myelodysplastic syndrome
CN104546848A (zh) 一种治疗结肠炎的药物
CN117224514B (zh) 一种化合物、组合物及其在制备治疗心律失常的药物中的应用