JP2022537551A5 - - Google Patents

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Publication number
JP2022537551A5
JP2022537551A5 JP2021575387A JP2021575387A JP2022537551A5 JP 2022537551 A5 JP2022537551 A5 JP 2022537551A5 JP 2021575387 A JP2021575387 A JP 2021575387A JP 2021575387 A JP2021575387 A JP 2021575387A JP 2022537551 A5 JP2022537551 A5 JP 2022537551A5
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JP
Japan
Application number
JP2021575387A
Other languages
Japanese (ja)
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JP2022537551A (ja
JPWO2020257671A5 (https=
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/038772 external-priority patent/WO2020257671A1/en
Publication of JP2022537551A publication Critical patent/JP2022537551A/ja
Publication of JPWO2020257671A5 publication Critical patent/JPWO2020257671A5/ja
Publication of JP2022537551A5 publication Critical patent/JP2022537551A5/ja
Pending legal-status Critical Current

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JP2021575387A 2019-06-20 2020-06-19 ベネトクラクス、ギルテリチニブ、ミドスタウリン、または白血病もしくは骨髄異形成症候群を治療するための他の化合物との組み合わせにおけるアザシチジン Pending JP2022537551A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962864413P 2019-06-20 2019-06-20
US62/864,413 2019-06-20
PCT/US2020/038772 WO2020257671A1 (en) 2019-06-20 2020-06-19 Azacitidine in combination with venetoclax, gilteritinib, midostaurin or other compounds for treating leukemia or myelodysplastic syndrome

Publications (3)

Publication Number Publication Date
JP2022537551A JP2022537551A (ja) 2022-08-26
JPWO2020257671A5 JPWO2020257671A5 (https=) 2023-06-08
JP2022537551A5 true JP2022537551A5 (https=) 2023-06-08

Family

ID=71528047

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021575387A Pending JP2022537551A (ja) 2019-06-20 2020-06-19 ベネトクラクス、ギルテリチニブ、ミドスタウリン、または白血病もしくは骨髄異形成症候群を治療するための他の化合物との組み合わせにおけるアザシチジン
JP2021575509A Pending JP2022537384A (ja) 2019-06-20 2020-06-19 ベネトクラクス、ギルテリチニブ、ミドスタウリン、または白血病もしくは骨髄異形成症候群を治療するための他の化合物との組み合わせにおけるアザシチジン

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021575509A Pending JP2022537384A (ja) 2019-06-20 2020-06-19 ベネトクラクス、ギルテリチニブ、ミドスタウリン、または白血病もしくは骨髄異形成症候群を治療するための他の化合物との組み合わせにおけるアザシチジン

Country Status (11)

Country Link
US (2) US12447171B2 (https=)
EP (2) EP3986403A1 (https=)
JP (2) JP2022537551A (https=)
KR (2) KR20220050874A (https=)
CN (2) CN114727996A (https=)
AU (2) AU2020296179A1 (https=)
BR (2) BR112021025537A2 (https=)
CA (2) CA3143719A1 (https=)
IL (2) IL289110A (https=)
MX (2) MX2021015993A (https=)
WO (2) WO2020257665A1 (https=)

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EP3597741A1 (en) 2012-04-27 2020-01-22 Duke University Genetic correction of mutated genes
US9828582B2 (en) 2013-03-19 2017-11-28 Duke University Compositions and methods for the induction and tuning of gene expression
US10676726B2 (en) 2015-02-09 2020-06-09 Duke University Compositions and methods for epigenome editing
EP4089175A1 (en) 2015-10-13 2022-11-16 Duke University Genome engineering with type i crispr systems in eukaryotic cells
EA201891317A3 (ru) 2015-11-30 2019-04-30 Дьюк Юниверсити Терапевтические мишени для коррекции гена дистрофина человека с помощью редактирования генов и способы их применения
US20190127713A1 (en) 2016-04-13 2019-05-02 Duke University Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use
WO2018017754A1 (en) 2016-07-19 2018-01-25 Duke University Therapeutic applications of cpf1-based genome editing
WO2019144061A1 (en) 2018-01-19 2019-07-25 Duke University Genome engineering with crispr-cas systems in eukaryotes
US20240141341A1 (en) * 2021-03-01 2024-05-02 Duke University Systems and methods for genome-wide annotation of gene regulatory elements linked to cell fitness
WO2022215995A1 (ko) * 2021-04-05 2022-10-13 주식회사 피노바이오 4'-티오-5-아자-2'-디옥시사이티딘 및 베네토클락스의 병용 요법
JP2024517318A (ja) * 2021-05-11 2024-04-19 アッヴィ・インコーポレイテッド アザシチジンと組み合わせて骨髄異形成症候群の処置に使用されるベネトクラクス投与レジメン
CN117651556A (zh) * 2021-05-11 2024-03-05 艾伯维公司 与cyp3a抑制剂和阿扎胞苷联合治疗骨髓增生异常综合征的维奈托克给药方案
US20250312327A1 (en) * 2021-10-14 2025-10-09 Pharos Ibio Co., Ltd Composition for combination therapy, comprising 2,3,5-substituted thiophene compound
TW202340177A (zh) 2021-12-30 2023-10-16 美商拜歐米富士恩股份有限公司 作為 flt3抑制劑之吡嗪化合物
IL317874A (en) 2022-06-24 2025-02-01 Tune Therapeutics Inc Compounds, systems and methods for reducing low density lipoproteins through targeted gene suppression

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
EP3782612B1 (en) * 2008-05-15 2023-11-08 Celgene Corporation Oral formulations of cytidine analogs and methods of use thereof
SI3137169T1 (sl) 2014-05-01 2022-04-29 Celgene Quanticel Research, Inc. Inhibitorji lizin specifične demetilaze-1
EA201790376A1 (ru) 2014-09-05 2017-08-31 Селджен Квонтисел Рисёрч, Инк. Ингибиторы лизин-специфической деметилазы-1
WO2016040238A1 (en) 2014-09-08 2016-03-17 Celgene Corporation Methods for treating a disease or disorder using oral formulations of cytidine analogs in combination with an anti-pd1 or anti-pdl1 monoclonal antibody
PT3362066T (pt) 2015-10-15 2021-11-16 Celgene Corp Terapia de combinação para tratar malignidades
US10695352B2 (en) 2015-10-15 2020-06-30 Celgene Corporation Combination therapy for treating malignancies
EP3371152B1 (en) 2015-11-05 2020-12-23 Celgene Quanticel Research, Inc. Compositions comprising an inhibitor of lysine specific demethylase-1 having a pyrimidine ring and its use in the treatment of cancer
CN109462980B (zh) * 2016-03-15 2022-02-08 奥莱松基因组股份有限公司 用于治疗血液恶性肿瘤的lsd1抑制剂的组合
US20200069677A1 (en) * 2016-12-09 2020-03-05 Constellation Pharmaceuticals, Inc. Markers for personalized cancer treatment with lsd1 inhibitors
EP4201399A3 (en) 2017-06-30 2023-08-09 Celgene Corporation Compositions and methods of use of 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl) methyl) -2,2-difluoroacetamide
WO2019012328A1 (en) 2017-07-09 2019-01-17 Biosight Pharma ANTICANCER POLY THERAPY
TWI848030B (zh) 2018-12-18 2024-07-11 比利時商阿根思公司 Cd70組合治療

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