|
US3808317A
(en)
|
1969-10-29 |
1974-04-30 |
Alcon Labor Inc |
Stabilized aqueous borate complexes of biologically active catechol amines
|
|
US3769424A
(en)
|
1970-10-01 |
1973-10-30 |
Merck & Co Inc |
Composition and method of treating dopamine deficiency in brain tissue
|
|
AU6889274A
(en)
|
1973-05-17 |
1975-11-20 |
Astra Laekemedel Ab |
Treatment of neurological disorders
|
|
US3936495A
(en)
|
1973-11-27 |
1976-02-03 |
Merck & Co., Inc. |
Purification process
|
|
US4166452A
(en)
|
1976-05-03 |
1979-09-04 |
Generales Constantine D J Jr |
Apparatus for testing human responses to stimuli
|
|
US4256108A
(en)
|
1977-04-07 |
1981-03-17 |
Alza Corporation |
Microporous-semipermeable laminated osmotic system
|
|
US4241082A
(en)
|
1977-09-02 |
1980-12-23 |
Sankyo Company Limited |
Agents for promoting reproductive ability of domestic animals
|
|
JPS5450700A
(en)
|
1977-09-28 |
1979-04-20 |
Sankyo Co |
Glazing agent of animal leather
|
|
JPS6021570B2
(ja)
|
1978-07-04 |
1985-05-28 |
三共株式会社 |
ド−パ類の高濃度製剤の製法
|
|
JPS56115749A
(en)
|
1980-02-18 |
1981-09-11 |
Sagami Chem Res Center |
Dopa derivative
|
|
US4265874A
(en)
|
1980-04-25 |
1981-05-05 |
Alza Corporation |
Method of delivering drug with aid of effervescent activity generated in environment of use
|
|
US4642316A
(en)
|
1985-05-20 |
1987-02-10 |
Warner-Lambert Company |
Parenteral phenytoin preparations
|
|
DE252290T1
(de)
|
1986-06-10 |
1988-06-09 |
Chiesi Farmaceutici S.P.A., Parma |
Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen.
|
|
US4832957A
(en)
|
1987-12-11 |
1989-05-23 |
Merck & Co., Inc. |
Controlled release combination of carbidopa/levodopa
|
|
US4684666A
(en)
|
1986-08-19 |
1987-08-04 |
Haas Pharmaceuticals, Inc. |
Stabilized liquid analgesic compositions
|
|
IT1226902B
(it)
|
1988-07-12 |
1991-02-21 |
Mini Ricerca Scient Tecnolog |
Processo per la sintesi del levodopa
|
|
US4963568A
(en)
|
1989-05-31 |
1990-10-16 |
Abbott Laboratories |
Dopamine agonists
|
|
US5350769A
(en)
|
1990-10-30 |
1994-09-27 |
Ss Pharmaceutical Co., Ltd. |
Antiinflammatory gel preparation
|
|
US5877176A
(en)
|
1991-12-26 |
1999-03-02 |
Cornell Research Foundation, Inc. |
Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis
|
|
CA2143070C
(en)
|
1994-02-22 |
2001-12-18 |
Pankaj Modi |
Oral controlled release liquid suspension pharmaceutical formulation
|
|
ATE258067T1
(de)
|
1995-05-26 |
2004-02-15 |
Pfizer |
Kombinationspräparat zur behandlung der parkinsonschen krankheit, das selektive nmda- antagonisten enthält
|
|
GB9523833D0
(en)
|
1995-11-22 |
1996-01-24 |
Boots Co Plc |
Medical treatment
|
|
IL119417A
(en)
|
1996-10-13 |
2003-02-12 |
Moshe Kushnir |
Pharmaceutical composition for transdermal administration of levodopa for parkinson's disease
|
|
US6746688B1
(en)
|
1996-10-13 |
2004-06-08 |
Neuroderm Ltd. |
Apparatus for the transdermal treatment of Parkinson's disease
|
|
US5861423A
(en)
|
1997-02-21 |
1999-01-19 |
Caldwell; William Scott |
Pharmaceutical compositions incorporating aryl substituted olefinic amine compounds
|
|
US6245917B1
(en)
|
1998-03-20 |
2001-06-12 |
Warner-Lambert Company |
Crystalline sodium phenytoin monohydrate
|
|
US7201923B1
(en)
|
1998-03-23 |
2007-04-10 |
General Mills, Inc. |
Encapsulation of sensitive liquid components into a matrix to obtain discrete shelf-stable particles
|
|
CA2327285C
(en)
|
1998-05-15 |
2005-06-14 |
Warner-Lambert Company |
Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same
|
|
US6274168B1
(en)
|
1999-02-23 |
2001-08-14 |
Mylan Pharmaceuticals Inc. |
Phenytoin sodium pharmaceutical compositions
|
|
US6716452B1
(en)
|
2000-08-22 |
2004-04-06 |
New River Pharmaceuticals Inc. |
Active agent delivery systems and methods for protecting and administering active agents
|
|
WO2000054773A1
(en)
|
1999-03-12 |
2000-09-21 |
Nitromed, Inc. |
Dopamine agonists in combination with nitric oxide donors, compositions and methods of use
|
|
FI109453B
(fi)
|
1999-06-30 |
2002-08-15 |
Orion Yhtymae Oyj |
Farmaseuttinen koostumus
|
|
US7479498B2
(en)
|
1999-08-23 |
2009-01-20 |
Phoenix Biosciences, Inc. |
Treatments for viral infections
|
|
US6348965B1
(en)
|
1999-09-24 |
2002-02-19 |
Henry Palladino |
Solid state fluorescence and absorption spectroscopy
|
|
SE0001151D0
(sv)
|
2000-03-31 |
2000-03-31 |
Amarin Dev Ab |
Method for producing a controlled-release composition
|
|
US20020028799A1
(en)
|
2000-07-06 |
2002-03-07 |
Naylor Alasdair Mark |
Treatment of male sexual dysfunction
|
|
GB0017387D0
(en)
|
2000-07-14 |
2000-08-30 |
Pfizer Ltd |
Novel enzyme
|
|
US20020099013A1
(en)
|
2000-11-14 |
2002-07-25 |
Thomas Piccariello |
Active agent delivery systems and methods for protecting and administering active agents
|
|
US20030119714A1
(en)
|
2000-12-15 |
2003-06-26 |
Naylor Alasdair Mark |
Treatment of male sexual dysfunction
|
|
US6989385B2
(en)
|
2000-12-21 |
2006-01-24 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
IL159812A0
(en)
|
2001-07-12 |
2004-06-20 |
Teva Pharma |
Dual release formulation comprising levodopa ethyl ester and a decarboxylase inhibitor in immediate release layer with levodopa ethyl ester in a controlled release core
|
|
WO2003034988A2
(en)
|
2001-10-19 |
2003-05-01 |
Idexx Laboratories, Inc. |
Injectable compositions for the controlled delivery of pharmacologically active compound
|
|
US6916813B2
(en)
|
2001-12-10 |
2005-07-12 |
Bristol-Myers Squibb Co. |
(1-phenyl-2-heteoaryl)ethyl-guanidine compounds as inhibitors of mitochondrial F1F0 ATP hydrolase
|
|
ES2189682B1
(es)
|
2001-12-11 |
2004-04-01 |
Laboratorios Del Dr. Esteve, S.A. |
Preparacion bebible que comprende ketoprofeno y su empleo en el tratamiento de procesos que cursan con fiebre, inflamacion y/o dolor, en un colectivo de animales, de forma simultanea.
|
|
US20060159751A1
(en)
|
2002-04-11 |
2006-07-20 |
Mona Gogia |
Controlled release pharmaceutical compositions of carbidopa and levodopa
|
|
US7985422B2
(en)
|
2002-08-05 |
2011-07-26 |
Torrent Pharmaceuticals Limited |
Dosage form
|
|
EP1551829B1
(de)
|
2002-10-10 |
2010-04-07 |
Morphochem Aktiengesellschaft Für Kombinatorische Chemie |
Neue verbindungen mit antibakterieller aktivität
|
|
WO2004069146A2
(en)
|
2003-02-07 |
2004-08-19 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
L-dopa amide derivatives and uses thereof
|
|
BRPI0412735A
(pt)
|
2003-07-18 |
2006-09-26 |
Baxter Int |
métodos para a fabricação, uso e composição de partìculas esféricas pequenas preparadas mediante a separação de fase controlada
|
|
US8173840B2
(en)
|
2003-07-29 |
2012-05-08 |
Signature R&D Holdings, Llc |
Compounds with high therapeutic index
|
|
US7589233B2
(en)
|
2003-07-29 |
2009-09-15 |
Signature R&D Holdings, Llc |
L-Threonine derivatives of high therapeutic index
|
|
GB0319935D0
(en)
|
2003-08-26 |
2003-09-24 |
Cipla Ltd |
Polymorphs
|
|
US8815950B2
(en)
|
2003-08-29 |
2014-08-26 |
Janssen Biotech, Inc. |
Pharmaceutical compositions and method of using levodopa and carbidopa
|
|
DE602004031134D1
(de)
|
2003-08-29 |
2011-03-03 |
Transform Pharmaceuticals Inc |
Pharmazeutische zusammensetzungen und verfahren zur verwendung von levodopa und carbidopa
|
|
US20050053669A1
(en)
|
2003-09-05 |
2005-03-10 |
Boehringer Ingelheim International Gmbh |
Administration form for the oral application of poorly soluble acidic and amphorteric drugs
|
|
KR20060108692A
(ko)
|
2003-10-31 |
2006-10-18 |
알자 코포레이션 |
메트포르민의 개선된 흡수를 위한 조성물 및 제형
|
|
WO2005099678A1
(en)
|
2004-04-06 |
2005-10-27 |
Transform Pharmaceuticals, Inc. |
Pharmaceutical compositions and method of using levodopa and carbidopa
|
|
SE0401842D0
(sv)
|
2004-07-12 |
2004-07-12 |
Dizlin Medical Design Ab |
Infusion and injection solution of levodopa
|
|
HRP20160455T1
(hr)
|
2004-09-09 |
2016-07-15 |
Yeda Research And Development Co., Ltd. |
Smjese polipeptida, sastavi koji ih sadrže i postupci za njihovu pripremu, te njihove primjene
|
|
WO2006037061A2
(en)
|
2004-09-28 |
2006-04-06 |
Farouk Karoum |
Compositions and methods of using d-dopa to treat parkinson's disease
|
|
US20060088607A1
(en)
|
2004-10-01 |
2006-04-27 |
Stefano George B |
Nutritional supplement compositions
|
|
WO2006043532A1
(ja)
|
2004-10-19 |
2006-04-27 |
Ono Pharmaceutical Co., Ltd. |
パーキンソン病治療剤
|
|
PL1896006T3
(pl)
|
2005-06-08 |
2010-03-31 |
Orion Corp |
Sposób wytwarzania granulek zawierających entakapon do postaci dawkowania doustnego
|
|
DE102006021872B4
(de)
|
2006-05-11 |
2008-04-17 |
Sanofi-Aventis |
4,5-Diphenyl-pyrimidinyl-oxy oder -mercapto substituierte Carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
WO2007138086A1
(en)
|
2006-05-31 |
2007-12-06 |
Solvay Pharmaceuticals Gmbh |
Long term 24 hour intestinal administration of levodopa/carbidopa
|
|
PE20080669A1
(es)
|
2006-09-08 |
2008-07-18 |
Drugtech Corp |
Composicion de liberacion sostenida que comprende levodopa
|
|
US8058243B2
(en)
|
2006-10-13 |
2011-11-15 |
Hsc Research And Development Limited Partnership |
Method for treating a brain cancer with ifenprodil
|
|
JP5631734B2
(ja)
|
2007-04-06 |
2014-11-26 |
トランスフオーム・フアーマシユーチカルズ・インコーポレーテツド |
流体薬物を供給するためのシステム及び方法
|
|
CL2008003507A1
(es)
|
2007-11-26 |
2009-11-27 |
Neuroderm Ltd |
Composicion farmaceutica que comprende nicotina y un inhibidor de la desensibilizacion del receptor de acetilcolina nicotinico (nachr) opipramol; kit farmaceutico; dispositivo medico; y uso para tratar una enfermedad o trastorno del sistema nervioso central o periferico.
|
|
CN101669925B
(zh)
|
2008-09-10 |
2011-08-10 |
天津药物研究院 |
干粉吸入剂、其制备方法和用途
|
|
WO2010055133A1
(en)
|
2008-11-14 |
2010-05-20 |
Neurosearch A/S |
Benzimidazole derivatives and their use for modulating the gabaa receptor complex
|
|
PL2432454T3
(pl)
|
2009-05-19 |
2017-10-31 |
Neuroderm Ltd |
Kompozycje do ciągłego podawania inhibitorów dopa-dekarboksylazy
|
|
US20130253056A1
(en)
|
2009-05-19 |
2013-09-26 |
Neuroderm, Ltd. |
Continuous Administration of Levodopa and/or Dopa Decarboxylase Inhibitors and Compositions for Same
|
|
CN101987081B
(zh)
|
2010-07-16 |
2012-08-08 |
钟术光 |
一种控释制剂
|
|
KR101187064B1
(ko)
|
2010-07-18 |
2012-09-28 |
주식회사 바이오폴리메드 |
양이온성 지질, 이의 제조 방법 및 이를 포함하는 세포내 이행성을 갖는 전달체
|
|
US10150792B2
(en)
|
2010-11-08 |
2018-12-11 |
Synthonics, Inc. |
Bismuth-containing compounds, coordination polymers, methods for modulating pharmacokinetic properties of biologically active agents, and methods for treating patients
|
|
TR201808178T4
(tr)
|
2010-11-15 |
2018-07-23 |
Neuroderm Ltd |
Aktif ajanların transdermal dağıtımı için bileşimler.
|
|
PT2640358T
(pt)
|
2010-11-15 |
2018-02-23 |
Neuroderm Ltd |
Administração contínua de l-dopa, inibidores de dopa descarboxilase, inibidores de catecol-o-metil transferase e composições para os mesmos
|
|
WO2012079072A2
(en)
|
2010-12-10 |
2012-06-14 |
Synagile Corporation |
Subcutaneously infusible levodopa prodrug compositions and methods of infusion
|
|
WO2013061161A2
(en)
|
2011-10-28 |
2013-05-02 |
Green Bcn Consulting Services Sl |
New combination therapies for treating neurological disorders
|
|
TR201204839A2
(tr)
|
2012-04-25 |
2012-12-21 |
Ali̇ Rai̇f İlaç Sanayi̇ A.Ş. |
Uzatılmış salım sağlayan levodopa karbıdopa entakapon içeren tablet formülasyonu.
|
|
WO2013184646A2
(en)
|
2012-06-05 |
2013-12-12 |
Synagile Corporation |
Dosing regimens for subcutaneously infusible acidic compositions
|
|
NZ703341A
(en)
|
2012-06-05 |
2016-11-25 |
Neuroderm Ltd |
Compositions comprising apomorphine and organic acids and uses thereof
|
|
AU2014229127B2
(en)
|
2013-03-13 |
2018-04-05 |
Neuroderm Ltd |
Method for treatment of parkinson's disease
|
|
US10258585B2
(en)
|
2014-03-13 |
2019-04-16 |
Neuroderm, Ltd. |
DOPA decarboxylase inhibitor compositions
|
|
DK3116475T3
(da)
|
2014-03-13 |
2020-12-07 |
Neuroderm Ltd |
Dopa-decarboxylasehæmmersammensætninger
|
|
RU2021103000A
(ru)
|
2014-10-21 |
2021-03-01 |
Эббви Инк. |
Пролекарства карбидопа и l-dopa и их применение для лечения болезни паркинсона
|
|
CN108495617A
(zh)
|
2015-11-24 |
2018-09-04 |
纽罗德姆有限公司 |
包含左旋多巴酰胺的药物组合物和其用途
|
|
WO2018154447A1
(en)
|
2017-02-21 |
2018-08-30 |
Neuroderm Ltd |
Dopa decarboxylase inhibitor compositions
|
|
WO2019038638A1
(en)
|
2017-08-21 |
2019-02-28 |
Neuroderm Ltd |
PROCESS FOR PREPARING AMIDE OF PURIFIED LEVODOPA
|
|
AR112683A1
(es)
|
2017-08-21 |
2019-11-27 |
Neuroderm Ltd |
Forma cristalina de base libre de levodopa, su sal de adición y composición farmaceutica que la comprende
|
|
AR112472A1
(es)
|
2017-08-21 |
2019-10-30 |
Neuroderm Ltd |
Forma de sales cristalinas de amida de levodopa y métodos para elaborarlas y usarlas
|
|
CN111643493B
(zh)
*
|
2020-05-26 |
2023-01-10 |
上海京新生物医药有限公司 |
一种高浓度左旋多巴制剂及其制备方法及其应用
|