JP2021527092A5 - - Google Patents

Info

Publication number
JP2021527092A5
JP2021527092A5 JP2020569024A JP2020569024A JP2021527092A5 JP 2021527092 A5 JP2021527092 A5 JP 2021527092A5 JP 2020569024 A JP2020569024 A JP 2020569024A JP 2020569024 A JP2020569024 A JP 2020569024A JP 2021527092 A5 JP2021527092 A5 JP 2021527092A5
Authority
JP
Japan
Prior art keywords
compound
subject
item
weeks
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020569024A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021527092A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/036848 external-priority patent/WO2019241442A1/en
Publication of JP2021527092A publication Critical patent/JP2021527092A/ja
Publication of JP2021527092A5 publication Critical patent/JP2021527092A5/ja
Priority to JP2023205211A priority Critical patent/JP2024028849A/ja
Priority to JP2025064902A priority patent/JP2025108553A/ja
Pending legal-status Critical Current

Links

JP2020569024A 2018-06-12 2019-06-12 19−ノルc3,3−二置換c21−n−ピラゾリルステロイドおよびその使用方法 Pending JP2021527092A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023205211A JP2024028849A (ja) 2018-06-12 2023-12-05 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法
JP2025064902A JP2025108553A (ja) 2018-06-12 2025-04-10 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862684155P 2018-06-12 2018-06-12
US62/684,155 2018-06-12
US201962789329P 2019-01-07 2019-01-07
US62/789,329 2019-01-07
US201962841645P 2019-05-01 2019-05-01
US62/841,645 2019-05-01
PCT/US2019/036848 WO2019241442A1 (en) 2018-06-12 2019-06-12 A 19-nor c3,3-disubstituted c21 -n-pyrazolyl steroid and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023205211A Division JP2024028849A (ja) 2018-06-12 2023-12-05 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法

Publications (2)

Publication Number Publication Date
JP2021527092A JP2021527092A (ja) 2021-10-11
JP2021527092A5 true JP2021527092A5 (enExample) 2022-06-16

Family

ID=67211854

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020569024A Pending JP2021527092A (ja) 2018-06-12 2019-06-12 19−ノルc3,3−二置換c21−n−ピラゾリルステロイドおよびその使用方法
JP2023205211A Pending JP2024028849A (ja) 2018-06-12 2023-12-05 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法
JP2025064902A Pending JP2025108553A (ja) 2018-06-12 2025-04-10 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023205211A Pending JP2024028849A (ja) 2018-06-12 2023-12-05 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法
JP2025064902A Pending JP2025108553A (ja) 2018-06-12 2025-04-10 19-ノルc3,3-二置換c21-n-ピラゾリルステロイドおよびその使用方法

Country Status (13)

Country Link
US (4) US20210338692A1 (enExample)
EP (1) EP3806863A1 (enExample)
JP (3) JP2021527092A (enExample)
KR (1) KR20210021005A (enExample)
CN (2) CN117959309A (enExample)
AU (2) AU2019287491B2 (enExample)
CA (1) CA3103421A1 (enExample)
IL (1) IL279315A (enExample)
MA (1) MA52894A (enExample)
MX (2) MX2020013557A (enExample)
SG (1) SG11202012344RA (enExample)
TW (1) TWI923545B (enExample)
WO (1) WO2019241442A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201606063RA (en) 2012-01-23 2016-09-29 Sage Therapeutics Inc Neuroactive steroid formulations and methods of treating cns disorders
RS62761B1 (sr) 2012-08-21 2022-01-31 Sage Therapeutics Inc Alopregnanolon za lečenje refraktornog epileptičkog statusa
SMT202100509T1 (it) 2013-04-17 2021-11-12 Sage Therapeutics Inc Steroide di c21-n-pirazolile 19-nor c3,3-disostituito per l'uso in terapia
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
JOP20200195A1 (ar) 2014-09-08 2017-06-16 Sage Therapeutics Inc سترويدات وتركيبات نشطة عصبياً، واستخداماتها
WO2016082789A1 (en) 2014-11-27 2016-06-02 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
WO2018013613A1 (en) 2016-07-11 2018-01-18 Sage Therapeutics, Inc. C17, c20, and c21 substituted neuroactive steroids and their methods of use
TW202604538A (zh) 2016-08-23 2026-02-01 美商賽吉醫療公司 結晶19-去甲c3,3-二取代之c21-n-吡唑類固醇
US20200291059A1 (en) 2017-12-08 2020-09-17 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
US20230018765A1 (en) * 2019-12-05 2023-01-19 Sage Therapeutics, Inc. A 19-nor c3,3-disubstituted c21-n-pyrazolyl steroid and methods of use thereof
CN115551514A (zh) 2020-03-25 2022-12-30 萨奇治疗股份有限公司 用于治疗呼吸系统病症的药物的用途
CA3187178A1 (en) * 2020-07-20 2022-01-27 Sage Therapeutics, Inc. Formulations of 19-nor c3,3- disubstituted c21-n-pyrazolyl steroid and methods of use thereof
WO2022165017A1 (en) * 2021-01-28 2022-08-04 Sage Therapeutics, Inc. Use of neuroactive steroids for treatment of sexual dysfunction
JP2024510436A (ja) * 2021-03-17 2024-03-07 セージ セラピューティクス, インコーポレイテッド 大うつ病性障害の処置のための19-ノルc3,3-2置換c21-n-ピラゾリルステロイド
MX2023012728A (es) * 2021-04-29 2023-11-08 Sage Therapeutics Inc Esteroide neuroactivo para el tratamiento del trastorno depresivo mayor y la depresion posparto en una mujer lactante.
MX2023012727A (es) * 2021-04-29 2023-11-08 Sage Therapeutics Inc Esteroide c21 -n-pirazolilo disubstituido 19-nor c3,3 para uso en el tratamiento de principales trastorno depresivo y depresion posparto.
JP2025508406A (ja) * 2022-02-16 2025-03-26 セージ セラピューティクス, インコーポレイテッド Cns関連障害を処置するための神経活性ステロイド
WO2025175214A1 (en) * 2024-02-16 2025-08-21 Engrail Therapeutics, Inc. Methods of treating generalized anxiety disorder

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SMT202100509T1 (it) * 2013-04-17 2021-11-12 Sage Therapeutics Inc Steroide di c21-n-pirazolile 19-nor c3,3-disostituito per l'uso in terapia
JOP20200195A1 (ar) * 2014-09-08 2017-06-16 Sage Therapeutics Inc سترويدات وتركيبات نشطة عصبياً، واستخداماتها
US20170233433A1 (en) * 2014-10-16 2017-08-17 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
PH12018501923B1 (en) * 2016-03-08 2024-06-28 Sage Therapeutics Inc Neuroactive steroids, compositions, and uses thereof
TW202604538A (zh) * 2016-08-23 2026-02-01 美商賽吉醫療公司 結晶19-去甲c3,3-二取代之c21-n-吡唑類固醇
EP3678670A1 (en) * 2017-09-07 2020-07-15 Sage Therapeutics, Inc. Neuroactive steroids and their methods of use

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