JP2021525087A5 - - Google Patents
Info
- Publication number
- JP2021525087A5 JP2021525087A5 JP2020565487A JP2020565487A JP2021525087A5 JP 2021525087 A5 JP2021525087 A5 JP 2021525087A5 JP 2020565487 A JP2020565487 A JP 2020565487A JP 2020565487 A JP2020565487 A JP 2020565487A JP 2021525087 A5 JP2021525087 A5 JP 2021525087A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- vhcdr2
- vhcdr1
- vhcdr3
- vlcdr1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024103786A JP2024150470A (ja) | 2018-06-01 | 2024-06-27 | 抗ｐｖｒｉｇ／抗ｔｉｇｉｔ二重特異性抗体および使用方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862679703P | 2018-06-01 | 2018-06-01 | |
| US62/679,703 | 2018-06-01 | ||
| US201862773586P | 2018-11-30 | 2018-11-30 | |
| US62/773,586 | 2018-11-30 | ||
| PCT/US2019/035062 WO2019232484A1 (en) | 2018-06-01 | 2019-05-31 | Anti-pvrig/anti-tigit bispecific antibodies and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024103786A Division JP2024150470A (ja) | 2018-06-01 | 2024-06-27 | 抗ｐｖｒｉｇ／抗ｔｉｇｉｔ二重特異性抗体および使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021525087A JP2021525087A (ja) | 2021-09-24 |
| JP2021525087A5 true JP2021525087A5 (https=) | 2022-06-08 |
| JP7646361B2 JP7646361B2 (ja) | 2025-03-17 |
Family
ID=67003669
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020565487A Active JP7646361B2 (ja) | 2018-06-01 | 2019-05-31 | 抗ｐｖｒｉｇ／抗ｔｉｇｉｔ二重特異性抗体および使用方法 |
| JP2024103786A Pending JP2024150470A (ja) | 2018-06-01 | 2024-06-27 | 抗ｐｖｒｉｇ／抗ｔｉｇｉｔ二重特異性抗体および使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024103786A Pending JP2024150470A (ja) | 2018-06-01 | 2024-06-27 | 抗ｐｖｒｉｇ／抗ｔｉｇｉｔ二重特異性抗体および使用方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20190382477A1 (https=) |
| EP (1) | EP3802605A1 (https=) |
| JP (2) | JP7646361B2 (https=) |
| KR (1) | KR20210016448A (https=) |
| CN (1) | CN113039202A (https=) |
| AU (1) | AU2019276578A1 (https=) |
| BR (1) | BR112020024249A2 (https=) |
| CA (1) | CA3101019A1 (https=) |
| CL (1) | CL2020003127A1 (https=) |
| CO (1) | CO2020016619A2 (https=) |
| IL (1) | IL279053A (https=) |
| MX (1) | MX2020012797A (https=) |
| SG (1) | SG11202011461TA (https=) |
| WO (1) | WO2019232484A1 (https=) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL272227B2 (en) * | 2017-07-27 | 2025-09-01 | iTeos Belgium SA | Anti-tigit antibodies |
| MX2021000745A (es) | 2018-07-20 | 2021-03-26 | Surface Oncology Inc | Composiciones anti-cd112r y metodos. |
| KR20210108978A (ko) | 2018-12-21 | 2021-09-03 | 오제 이뮈노테라프틱스 | 이작용성 항-pd-1/il-7 분자 |
| WO2020165374A1 (en) | 2019-02-14 | 2020-08-20 | Ose Immunotherapeutics | Bifunctional molecule comprising il-15ra |
| US20220267467A1 (en) * | 2019-07-19 | 2022-08-25 | WuXi Biologics Ireland Limited | Polypeptide complex for conjugation and use thereof |
| WO2021122866A1 (en) | 2019-12-17 | 2021-06-24 | Ose Immunotherapeutics | Bifunctional molecules comprising an il-7 variant |
| CA3170025A1 (en) * | 2020-03-13 | 2021-09-16 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Pvrig binding protein and its medical uses |
| CN115943312A (zh) | 2020-05-07 | 2023-04-07 | 法国居里学院 | 免疫抑制性成纤维细胞群体的生物标志物antxr1及其在预测对免疫疗法的反应中的用途 |
| KR20230024368A (ko) | 2020-06-18 | 2023-02-20 | 제넨테크, 인크. | 항-tigit 항체 및 pd-1 축 결합 길항제를 사용한 치료 |
| CA3188566A1 (en) * | 2020-07-03 | 2022-01-06 | Suzhou Alphamab Co., Ltd. | Coagulation factor xi (fxi) binding protein |
| TW202216778A (zh) | 2020-07-15 | 2022-05-01 | 美商安進公司 | Ｔｉｇｉｔ及ｃｄ１１２ｒ阻斷 |
| US11028172B1 (en) * | 2020-11-10 | 2021-06-08 | Lepu Biopharma Co., Ltd. | Anti-TIGIT antibodies and uses thereof |
| WO2022112198A1 (en) | 2020-11-24 | 2022-06-02 | Worldwide Innovative Network | Method to select the optimal immune checkpoint therapies |
| WO2022148781A1 (en) | 2021-01-05 | 2022-07-14 | Institut Curie | Combination of mcoln activators and immune checkpoint inhibitors |
| WO2022165266A1 (en) * | 2021-01-28 | 2022-08-04 | Compugen Ltd. | Anti-pvrig antibodies formulations and uses thereof |
| WO2022165275A2 (en) * | 2021-01-28 | 2022-08-04 | Compugen Ltd. | Combination therapy with anti-pvrig antibodies formulations and anti-pd-1-antibodies |
| WO2022171080A1 (zh) * | 2021-02-09 | 2022-08-18 | 上海君实生物医药科技股份有限公司 | 抗cd112r抗体及其用途 |
| MX2023009434A (es) | 2021-02-11 | 2023-08-15 | Nectin Therapeutics Ltd | Anticuerpos contra cd112r y usos de los mismos. |
| EP4320156A1 (en) | 2021-04-09 | 2024-02-14 | Ose Immunotherapeutics | Scaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains |
| MX2023011964A (es) | 2021-04-09 | 2024-01-08 | Ose Immunotherapeutics | Nuevo andamio para moléculas bifuncionales con propiedades mejoradas. |
| WO2022258049A1 (en) * | 2021-06-10 | 2022-12-15 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Genetically modified non-human animal with human or chimeric pvrig |
| EP4363450A1 (en) * | 2021-07-01 | 2024-05-08 | Compugen Ltd. | Anti-tigit and anti-pvrig in monotherapy and combination treatments |
| WO2023010094A2 (en) | 2021-07-28 | 2023-02-02 | Genentech, Inc. | Methods and compositions for treating cancer |
| US20240343803A1 (en) * | 2021-07-30 | 2024-10-17 | Shandong Simcere Biopharmaceutical Co., Ltd. | Anti-Pvrig/Anti-Tigit Bispecific Antibodies And Applications Thereof |
| EP4403574A4 (en) | 2021-09-15 | 2025-10-29 | Jiangsu Hengrui Pharmaceuticals Co Ltd | PD-1-Specific Protein and Its Pharmaceutical Use |
| EP4403573A4 (en) * | 2021-09-15 | 2024-12-25 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | PHARMACEUTICAL COMPOSITION CONTAINING BISPECIFIC ANTI-PVRIG/TIGIT ANTIBODY |
| WO2023056403A1 (en) | 2021-09-30 | 2023-04-06 | Genentech, Inc. | Methods for treatment of hematologic cancers using anti-tigit antibodies, anti-cd38 antibodies, and pd-1 axis binding antagonists |
| CN114057867B (zh) * | 2021-12-14 | 2023-05-12 | 河南联科物联网科技有限公司 | 一种抗减蛋综合征的单克隆抗体及其应用 |
| CN115819582A (zh) * | 2021-12-24 | 2023-03-21 | 合肥天港免疫药物有限公司 | Pvrig的抗体或其抗原结合片段及其应用 |
| CN116925233A (zh) * | 2022-04-02 | 2023-10-24 | 普米斯生物技术(珠海)有限公司 | 抗tigit-抗pvrig双特异性抗体、其药物组合物及用途 |
| CN116925222A (zh) * | 2022-04-02 | 2023-10-24 | 普米斯生物技术(珠海)有限公司 | 抗pvrig抗体、其药物组合物及用途 |
| KR20250022049A (ko) | 2022-06-07 | 2025-02-14 | 제넨테크, 인크. | 항-pd-l1 길항제 및 항-tigit 길항제 항체를 포함하는, 폐암 치료의 효율을 결정하는 방법 |
| CN119487079A (zh) * | 2022-06-08 | 2025-02-18 | 山东先声生物制药有限公司 | 一种pvrig/tigit双特异性抗体药物组合物及其用途 |
| WO2024003360A1 (en) | 2022-07-01 | 2024-01-04 | Institut Curie | Biomarkers and uses thereof for the treatment of neuroblastoma |
| JP2025525886A (ja) | 2022-08-02 | 2025-08-07 | オーエスイー・イミュノセラピューティクス | Ｃｄ２８に対する多機能性分子 |
| CN120513101A (zh) * | 2023-01-19 | 2025-08-19 | 山东先声生物制药有限公司 | 抗pvrig/抗tigit双特异性抗体在治疗恶性肿瘤中的用途 |
| KR20250156744A (ko) | 2023-03-15 | 2025-11-03 | 상하이 맙젠 바이오텍 리미티드 | Pd-1/pvrig/tigit 결합 단백질을 함유하는 약학적 조성물 및 이의 의약적 용도 |
| EP4687991A1 (en) | 2023-03-30 | 2026-02-11 | Ose Immunotherapeutics | Lipid-based nanoparticle targeted at activated immune cells for the expression of immune cell enhancing molecule and use thereof |
| WO2024200820A1 (en) | 2023-03-30 | 2024-10-03 | Ose Immunotherapeutics | Method of synthesis of targeted lipid nanoparticle and uses thereof |
| EP4724495A1 (en) * | 2023-06-06 | 2026-04-15 | WuXi Biologics Ireland Limited | Anti-tigit x pvrig antibodies and uses thereof |
| IL325744A (en) * | 2023-07-07 | 2026-03-01 | D3 Bio Wuxi Co Ltd | Combination therapies for cancer treatment |
| WO2025068452A1 (en) | 2023-09-29 | 2025-04-03 | Negio Therapeutics | Guanfacine derivatives and their use in treating cancer |
| WO2025068461A1 (en) | 2023-09-29 | 2025-04-03 | Negio Therapeutics | Guanfacine derivatives and their use in treating cancer |
| WO2025132831A1 (en) | 2023-12-19 | 2025-06-26 | Universite D'aix-Marseille | N-heteroaryl derivatives and uses thereof for treating cancer |
| CN120230207A (zh) * | 2023-12-29 | 2025-07-01 | 百奥泰生物制药股份有限公司 | Pvrig结合蛋白、双特异性抗体及其应用 |
| WO2025242835A1 (en) | 2024-05-22 | 2025-11-27 | Ose Immunotherapeutics | Molecules comprising masking linkers and uses thereof for the treatment of cancer |
| WO2025242836A1 (en) | 2024-05-22 | 2025-11-27 | Ose Immunotherapeutics | Molecules comprising masking linkers and uses thereof for the treatment of auto-immune or inflammatory diseases and disorders |
| WO2025262250A1 (en) | 2024-06-20 | 2025-12-26 | Negio Therapeutics | Guanfacine derivatives and their uses |
| WO2026068705A1 (en) | 2024-09-26 | 2026-04-02 | Ose Immunotherapeutics | Lipid-based nanoparticles comprising non-glycosylated fc domains and uses thereof |
| CN120058919B (zh) * | 2025-04-29 | 2025-07-18 | 浙江大学杭州国际科创中心 | 抗裂谷热病毒Gn蛋白的单抗及在病毒检测中的应用 |
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| PL209392B1 (pl) | 1999-01-15 | 2011-08-31 | Genentech Inc | Przeciwciało, komórka gospodarza, sposób wytwarzania przeciwciała oraz zastosowanie przeciwciała |
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| HRP20241208T1 (hr) | 2010-04-20 | 2024-11-22 | Genmab A/S | Heterodimerni proteini koji sadrže fc fragment protutijela i postupci za njihovu proizvodnju |
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| US10407484B2 (en) | 2015-09-02 | 2019-09-10 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for modulating T-cell mediated immune response |
| PT3356413T (pt) | 2015-10-01 | 2022-04-04 | Potenza Therapeutics Inc | Proteínas de ligação a antigénio anti-tigit e métodos de utilização das mesmas |
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| JP7010854B2 (ja) | 2016-06-14 | 2022-01-26 | ゼンコア インコーポレイテッド | 二重特異性チェックポイント阻害剤抗体 |
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| IL317989A (en) | 2016-08-17 | 2025-02-01 | Compugen Ltd | Anti-TIGIT antibodies, anti-PVRIG antibodies and combinations thereof |
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| JP7348072B2 (ja) * | 2017-06-01 | 2023-09-20 | コンピュジェン リミテッド | 三重併用抗体療法 |
| KR102185854B1 (ko) | 2017-09-09 | 2020-12-02 | 애플 인크. | 생체측정 인증의 구현 |
-
2019
- 2019-05-31 KR KR1020207038135A patent/KR20210016448A/ko not_active Ceased
- 2019-05-31 BR BR112020024249-7A patent/BR112020024249A2/pt unknown
- 2019-05-31 CN CN201980050598.6A patent/CN113039202A/zh active Pending
- 2019-05-31 MX MX2020012797A patent/MX2020012797A/es unknown
- 2019-05-31 AU AU2019276578A patent/AU2019276578A1/en not_active Abandoned
- 2019-05-31 SG SG11202011461TA patent/SG11202011461TA/en unknown
- 2019-05-31 CA CA3101019A patent/CA3101019A1/en active Pending
- 2019-05-31 WO PCT/US2019/035062 patent/WO2019232484A1/en not_active Ceased
- 2019-05-31 EP EP19733259.6A patent/EP3802605A1/en active Pending
- 2019-05-31 US US16/428,856 patent/US20190382477A1/en active Pending
- 2019-05-31 JP JP2020565487A patent/JP7646361B2/ja active Active
-
2020
- 2020-11-29 IL IL279053A patent/IL279053A/en unknown
- 2020-12-01 CL CL2020003127A patent/CL2020003127A1/es unknown
- 2020-12-30 CO CONC2020/0016619A patent/CO2020016619A2/es unknown
-
2024
- 2024-06-27 JP JP2024103786A patent/JP2024150470A/ja active Pending
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