JP2022542505A5 - - Google Patents
Info
- Publication number
- JP2022542505A5 JP2022542505A5 JP2022505499A JP2022505499A JP2022542505A5 JP 2022542505 A5 JP2022542505 A5 JP 2022542505A5 JP 2022505499 A JP2022505499 A JP 2022505499A JP 2022505499 A JP2022505499 A JP 2022505499A JP 2022542505 A5 JP2022542505 A5 JP 2022542505A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- pharmaceutical formulation
- liquid pharmaceutical
- stable liquid
- formulation according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962880021P | 2019-07-29 | 2019-07-29 | |
| US62/880,021 | 2019-07-29 | ||
| US201962893051P | 2019-08-28 | 2019-08-28 | |
| US62/893,051 | 2019-08-28 | ||
| US201962930206P | 2019-11-04 | 2019-11-04 | |
| US62/930,206 | 2019-11-04 | ||
| US202062968660P | 2020-01-31 | 2020-01-31 | |
| US62/968,660 | 2020-01-31 | ||
| US202062985702P | 2020-03-05 | 2020-03-05 | |
| US62/985,702 | 2020-03-05 | ||
| US202063009367P | 2020-04-13 | 2020-04-13 | |
| US63/009,367 | 2020-04-13 | ||
| PCT/US2020/043921 WO2021021837A2 (en) | 2019-07-29 | 2020-07-28 | Anti-pvrig antibodies formulations and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022542505A JP2022542505A (ja) | 2022-10-04 |
| JP2022542505A5 true JP2022542505A5 (https=) | 2023-08-29 |
Family
ID=72243187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022505499A Pending JP2022542505A (ja) | 2019-07-29 | 2020-07-28 | 抗ｐｖｒｉｇ抗体製剤およびそれらの使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220280643A1 (https=) |
| EP (1) | EP4003417A2 (https=) |
| JP (1) | JP2022542505A (https=) |
| KR (1) | KR20220041881A (https=) |
| CN (1) | CN114615993A (https=) |
| AU (1) | AU2020323926A1 (https=) |
| BR (1) | BR112022001575A2 (https=) |
| CA (1) | CA3149093A1 (https=) |
| IL (1) | IL290141A (https=) |
| MX (1) | MX2022001146A (https=) |
| WO (1) | WO2021021837A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL317989A (en) | 2016-08-17 | 2025-02-01 | Compugen Ltd | Anti-TIGIT antibodies, anti-PVRIG antibodies and combinations thereof |
| TW202216778A (zh) | 2020-07-15 | 2022-05-01 | 美商安進公司 | Ｔｉｇｉｔ及ｃｄ１１２ｒ阻斷 |
| WO2022069940A1 (en) * | 2020-09-30 | 2022-04-07 | Compugen Ltd. | Combination therapy with anti-pvrig antibodies formulations, anti-tigit antibodies, and anti-pd-1 antibodies |
| WO2022171080A1 (zh) * | 2021-02-09 | 2022-08-18 | 上海君实生物医药科技股份有限公司 | 抗cd112r抗体及其用途 |
| EP4403574A4 (en) | 2021-09-15 | 2025-10-29 | Jiangsu Hengrui Pharmaceuticals Co Ltd | PD-1-Specific Protein and Its Pharmaceutical Use |
| EP4403573A4 (en) * | 2021-09-15 | 2024-12-25 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | PHARMACEUTICAL COMPOSITION CONTAINING BISPECIFIC ANTI-PVRIG/TIGIT ANTIBODY |
| WO2024027824A1 (zh) * | 2022-08-05 | 2024-02-08 | 上海君实生物医药科技股份有限公司 | 抗cd112r抗体药物组合物及其用途 |
| CN120112553A (zh) * | 2022-08-10 | 2025-06-06 | 广州百济神州生物制药有限公司 | 抗pvrig抗体和使用方法 |
| CN117957254A (zh) * | 2022-08-31 | 2024-04-30 | 石药集团巨石生物制药有限公司 | 抗pvrig抗体及其应用 |
| KR20250156744A (ko) | 2023-03-15 | 2025-11-03 | 상하이 맙젠 바이오텍 리미티드 | Pd-1/pvrig/tigit 결합 단백질을 함유하는 약학적 조성물 및 이의 의약적 용도 |
| WO2024245388A1 (zh) * | 2023-06-01 | 2024-12-05 | 信达生物制药(苏州)有限公司 | 抗pvrig抗体及其应用 |
| TW202502812A (zh) * | 2023-06-06 | 2025-01-16 | 大陸商上海藥明生物技術有限公司 | 抗pvrig抗體及其用途 |
| CN120005023B (zh) * | 2023-12-22 | 2025-12-26 | 华润生物医药有限公司 | 抗pvrig抗体及其用途 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9714A (en) | 1853-05-10 | Machine fob making hook-headed spikes | ||
| US289A (en) | 1837-07-19 | Cooking-stove | ||
| DE3572982D1 (en) | 1984-03-06 | 1989-10-19 | Takeda Chemical Industries Ltd | Chemically modified lymphokine and production thereof |
| JP3101690B2 (ja) | 1987-03-18 | 2000-10-23 | エス・ビィ・２・インコーポレイテッド | 変性抗体の、または変性抗体に関する改良 |
| US5677425A (en) | 1987-09-04 | 1997-10-14 | Celltech Therapeutics Limited | Recombinant antibody |
| WO1990006952A1 (fr) | 1988-12-22 | 1990-06-28 | Kirin-Amgen, Inc. | Facteur de stimulation de colonies de granulocytes modifies chimiquement |
| CA2118508A1 (en) | 1992-04-24 | 1993-11-11 | Elizabeth S. Ward | Recombinant production of immunoglobulin-like domains in prokaryotic cells |
| ES2156149T3 (es) | 1992-12-04 | 2001-06-16 | Medical Res Council | Proteinas de union multivalente y multiespecificas, su fabricacion y su uso. |
| AU691811B2 (en) | 1993-06-16 | 1998-05-28 | Celltech Therapeutics Limited | Antibodies |
| US6121022A (en) | 1995-04-14 | 2000-09-19 | Genentech, Inc. | Altered polypeptides with increased half-life |
| US5869046A (en) | 1995-04-14 | 1999-02-09 | Genentech, Inc. | Altered polypeptides with increased half-life |
| US6277375B1 (en) | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| US6194551B1 (en) | 1998-04-02 | 2001-02-27 | Genentech, Inc. | Polypeptide variants |
| DK1071700T3 (da) | 1998-04-20 | 2010-06-07 | Glycart Biotechnology Ag | Glykosylerings-modifikation af antistoffer til forbedring af antistofafhængig cellulær cytotoksicitet |
| IL127127A0 (en) | 1998-11-18 | 1999-09-22 | Peptor Ltd | Small functional units of antibody heavy chain variable regions |
| US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| PL209392B1 (pl) | 1999-01-15 | 2011-08-31 | Genentech Inc | Przeciwciało, komórka gospodarza, sposób wytwarzania przeciwciała oraz zastosowanie przeciwciała |
| CA2704600C (en) | 1999-04-09 | 2016-10-25 | Kyowa Kirin Co., Ltd. | A method for producing antibodies with increased adcc activity |
| CA2463879C (en) | 2001-10-25 | 2012-12-04 | Genentech, Inc. | Glycoprotein compositions |
| BR0309145A (pt) | 2002-04-09 | 2005-02-01 | Kyowa Hakko Kogyo Kk | Células das quais o genoma é modificado |
| MXPA05010555A (es) * | 2003-04-04 | 2006-03-09 | Genentech Inc | Formulaciones de proteina y anticuerpo de alta concentracion. |
| US8367805B2 (en) | 2004-11-12 | 2013-02-05 | Xencor, Inc. | Fc variants with altered binding to FcRn |
| EP3409289B1 (en) * | 2010-02-26 | 2020-09-30 | Novo Nordisk A/S | Stable antibody containing compositions |
| TWI694836B (zh) * | 2014-05-16 | 2020-06-01 | 英商葛蘭素史克智慧財產管理有限公司 | 抗體調配物 |
| DK3653221T5 (da) * | 2015-02-19 | 2024-08-26 | Compugen Ltd | Anti-pvrig-antistoffer og anvendelsesfremgangsmåder |
| US10550173B2 (en) * | 2015-02-19 | 2020-02-04 | Compugen, Ltd. | PVRIG polypeptides and methods of treatment |
| WO2017165736A1 (en) * | 2016-03-25 | 2017-09-28 | Visterra, Inc. | Formulation of antibody molecules to dengue virus |
| IL317989A (en) * | 2016-08-17 | 2025-02-01 | Compugen Ltd | Anti-TIGIT antibodies, anti-PVRIG antibodies and combinations thereof |
| CR20190291A (es) * | 2016-12-23 | 2019-11-05 | Serum Institute Of India Pvt Ltd | Métodos mejorados para estimular la productividad de anticuerpos en el cultivo de células de mamiferos y reducir la agregación durante los procesos de formulación post-tratamiento (downstream) y formulaciones de anticuerpos estables obtenidas a partir de los mismos |
| JP7348072B2 (ja) * | 2017-06-01 | 2023-09-20 | コンピュジェン リミテッド | 三重併用抗体療法 |
| JP2023500651A (ja) * | 2019-11-04 | 2023-01-10 | コンピュジェン リミテッド | 抗ｐｖｒｉｇ抗体製剤および抗ｐｄ－１抗体による併用療法 |
| WO2022069940A1 (en) * | 2020-09-30 | 2022-04-07 | Compugen Ltd. | Combination therapy with anti-pvrig antibodies formulations, anti-tigit antibodies, and anti-pd-1 antibodies |
| WO2022165275A2 (en) * | 2021-01-28 | 2022-08-04 | Compugen Ltd. | Combination therapy with anti-pvrig antibodies formulations and anti-pd-1-antibodies |
| WO2022165266A1 (en) * | 2021-01-28 | 2022-08-04 | Compugen Ltd. | Anti-pvrig antibodies formulations and uses thereof |
| US12462008B2 (en) | 2021-04-23 | 2025-11-04 | Beijing Boe Technology Development Co., Ltd. | Unlocking control method and device, electronic apparatus, and computer-readable storage medium |
| WO2023064958A1 (en) * | 2021-10-15 | 2023-04-20 | Compugen Ltd. | Combination therapy with anti-pvrig antibodies formulations, anti-tigit antibodies, and anti-pd-1 antibodies |
| US20240103010A1 (en) * | 2022-03-18 | 2024-03-28 | Compugen Ltd. | Pvrl2 and/or pvrig as biomarkers for treatment |
| TW202515608A (zh) * | 2023-06-26 | 2025-04-16 | 以色列商坎布根有限公司 | Ｉｌ—１８ｂｐ拮抗抗體及其於癌症治療之單一療法及組合療法的用途 |
-
2020
- 2020-07-28 EP EP20761926.3A patent/EP4003417A2/en active Pending
- 2020-07-28 JP JP2022505499A patent/JP2022542505A/ja active Pending
- 2020-07-28 BR BR112022001575A patent/BR112022001575A2/pt unknown
- 2020-07-28 MX MX2022001146A patent/MX2022001146A/es unknown
- 2020-07-28 AU AU2020323926A patent/AU2020323926A1/en active Pending
- 2020-07-28 CN CN202080060763.9A patent/CN114615993A/zh active Pending
- 2020-07-28 KR KR1020227006619A patent/KR20220041881A/ko active Pending
- 2020-07-28 CA CA3149093A patent/CA3149093A1/en active Pending
- 2020-07-28 US US17/631,847 patent/US20220280643A1/en active Pending
- 2020-07-28 WO PCT/US2020/043921 patent/WO2021021837A2/en not_active Ceased
-
2022
- 2022-01-26 IL IL290141A patent/IL290141A/en unknown
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