JP2024509018A5 - - Google Patents

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Publication number
JP2024509018A5
JP2024509018A5 JP2023514810A JP2023514810A JP2024509018A5 JP 2024509018 A5 JP2024509018 A5 JP 2024509018A5 JP 2023514810 A JP2023514810 A JP 2023514810A JP 2023514810 A JP2023514810 A JP 2023514810A JP 2024509018 A5 JP2024509018 A5 JP 2024509018A5
Authority
JP
Japan
Prior art keywords
seq
amino acid
variable region
chain variable
immunoglobulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023514810A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024509018A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/080107 external-priority patent/WO2022188832A1/zh
Publication of JP2024509018A publication Critical patent/JP2024509018A/ja
Publication of JP2024509018A5 publication Critical patent/JP2024509018A5/ja
Pending legal-status Critical Current

Links

JP2023514810A 2021-03-12 2022-03-10 抗ｐｄ－１－抗ｖｅｇｆａ二重特異性抗体を含有する組合せ医薬及びその使用 Pending JP2024509018A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202110270652 2021-03-12
CN202110270652.7 2021-03-12
PCT/CN2022/080107 WO2022188832A1 (zh) 2021-03-12 2022-03-10 含有抗pd-1-抗vegfa双特异性抗体的药物组合及其用途

Publications (2)

Publication Number Publication Date
JP2024509018A JP2024509018A (ja) 2024-02-29
JP2024509018A5 true JP2024509018A5 (https=) 2025-03-26

Family

ID=83227452

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023514810A Pending JP2024509018A (ja) 2021-03-12 2022-03-10 抗ｐｄ－１－抗ｖｅｇｆａ二重特異性抗体を含有する組合せ医薬及びその使用

Country Status (11)

Country Link
US (1) US20250114450A1 (https=)
EP (1) EP4190819A4 (https=)
JP (1) JP2024509018A (https=)
KR (1) KR20230156910A (https=)
CN (1) CN115068603A (https=)
AU (1) AU2022233411A1 (https=)
BR (1) BR112023018457A2 (https=)
CA (1) CA3193662A1 (https=)
IL (1) IL305805A (https=)
MX (1) MX2023010681A (https=)
WO (1) WO2022188832A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115785269B (zh) * 2022-11-01 2023-09-22 四川大学 抗pd-l1的抗体及其应用
CN118591562A (zh) * 2022-12-30 2024-09-03 上海荣昌生物科技有限公司 一种双特异性抗体及其应用
CN118620082A (zh) * 2023-03-10 2024-09-10 南京维立志博生物科技有限公司 靶向vegf途径和pd-1的双特异性抗原结合蛋白、其组合物和用途
WO2025056056A1 (zh) * 2023-09-14 2025-03-20 中山康方生物医药有限公司 药物组合及用途
WO2025103407A1 (zh) * 2023-11-16 2025-05-22 江苏豪森药业集团有限公司 抗体药物偶联物和多腺苷二磷酸核糖聚合酶抑制剂的联合应用
WO2025157267A1 (zh) * 2024-01-25 2025-07-31 中山康方生物医药有限公司 抗pd-1-抗vegfa的双特异性抗体的医药用途
WO2025201450A1 (zh) * 2024-03-27 2025-10-02 康方汇科(上海)生物有限公司 药物组合及用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5747654A (en) 1993-06-14 1998-05-05 The United States Of America As Represented By The Department Of Health And Human Services Recombinant disulfide-stabilized polypeptide fragments having binding specificity
KR100816621B1 (ko) 1997-04-07 2008-03-24 제넨테크, 인크. 항-ｖｅｇｆ 항체
CN106967172B (zh) 2016-08-23 2019-01-08 康方药业有限公司 抗ctla4-抗pd-1 双功能抗体、其药物组合物及其用途
CN106977602B (zh) * 2016-08-23 2018-09-25 中山康方生物医药有限公司 一种抗pd1单克隆抗体、其药物组合物及其用途
TW202444417A (zh) * 2017-05-09 2024-11-16 美商提薩羅有限公司 治療癌症的組合療法
WO2019148412A1 (en) * 2018-02-01 2019-08-08 Merck Sharp & Dohme Corp. Anti-pd-1/lag3 bispecific antibodies
CA3090878A1 (en) * 2018-02-11 2019-08-15 Beijing Hanmi Pharmaceutical Co., Ltd. Anti-pd-1/anti-vegf natural antibody structure-like heterodimeric form bispecific antibody and preparation thereof
CN109053895B (zh) * 2018-08-30 2020-06-09 中山康方生物医药有限公司 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途
CN112972675A (zh) * 2018-09-07 2021-06-18 上海君实生物医药科技股份有限公司 抗pd-1抗体在治疗肿瘤中的用途
WO2021023117A1 (zh) * 2019-08-02 2021-02-11 康方药业有限公司 抗ctla4-抗pd-1双特异性抗体及其用途
BR112022002028A2 (pt) * 2019-08-02 2022-04-12 Cttq Akeso Shanghai Biomed Tech Co Ltd Anticorpo anti-pd-1 e uso farmacêutico do mesmo
US11661454B2 (en) * 2019-08-09 2023-05-30 Anhui Biox Vision Biological Technology Co., Ltd. Anti-VEGF-PD1 bispecific antibody with novel structure and use thereof
PH12022551278A1 (en) * 2019-11-25 2023-11-20 Akeso Biopharma Inc Anti-pd-1-anti-vegfa bispecific antibody, pharmaceutical composition and use thereof
CN110960543A (zh) * 2019-12-10 2020-04-07 安徽瀚海博兴生物技术有限公司 一种联合抗vegf-抗pd1双特异性抗体用于制备抗癌药物

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