JP2024515396A5 - - Google Patents
Info
- Publication number
- JP2024515396A5 JP2024515396A5 JP2023514956A JP2023514956A JP2024515396A5 JP 2024515396 A5 JP2024515396 A5 JP 2024515396A5 JP 2023514956 A JP2023514956 A JP 2023514956A JP 2023514956 A JP2023514956 A JP 2023514956A JP 2024515396 A5 JP2024515396 A5 JP 2024515396A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- seq
- antibody
- amino acid
- variable region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110404033.2 | 2021-04-14 | ||
| CN202110404033 | 2021-04-14 | ||
| PCT/CN2022/086890 WO2022218384A1 (zh) | 2021-04-14 | 2022-04-14 | 抗cd47的单克隆抗体及其用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024515396A JP2024515396A (ja) | 2024-04-10 |
| JP2024515396A5 true JP2024515396A5 (https=) | 2025-02-28 |
Family
ID=83575257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023514956A Pending JP2024515396A (ja) | 2021-04-14 | 2022-04-14 | 抗ｃｄ４７モノクローナル抗体及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240043531A1 (https=) |
| EP (1) | EP4190816A4 (https=) |
| JP (1) | JP2024515396A (https=) |
| KR (1) | KR20230170648A (https=) |
| CN (1) | CN115192718A (https=) |
| AU (1) | AU2022258273A1 (https=) |
| BR (1) | BR112023018450A2 (https=) |
| CA (1) | CA3193664A1 (https=) |
| IL (1) | IL305363A (https=) |
| MX (1) | MX2023010687A (https=) |
| WO (1) | WO2022218384A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109053895B (zh) * | 2018-08-30 | 2020-06-09 | 中山康方生物医药有限公司 | 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途 |
| BR112022002028A2 (pt) * | 2019-08-02 | 2022-04-12 | Cttq Akeso Shanghai Biomed Tech Co Ltd | Anticorpo anti-pd-1 e uso farmacêutico do mesmo |
| CA3208447A1 (en) * | 2022-09-09 | 2024-03-09 | Akeso Biopharma, Inc. | Therapeutic combination and use thereof |
| CN119823266A (zh) * | 2023-10-13 | 2025-04-15 | 英脉德医疗科技(广东)有限公司 | 肿瘤微环境特异激活的cd47抗体 |
| WO2025201450A1 (zh) * | 2024-03-27 | 2025-10-02 | 康方汇科(上海)生物有限公司 | 药物组合及用途 |
| WO2026051964A1 (en) * | 2024-09-04 | 2026-03-12 | Akeso Biopharma Co., Ltd. | Antibody that binds vegfa and pd-1 and uses thereof to treat cancers |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| EP0281604B1 (en) | 1986-09-02 | 1993-03-31 | Enzon Labs Inc. | Single polypeptide chain binding molecules |
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5747654A (en) | 1993-06-14 | 1998-05-05 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant disulfide-stabilized polypeptide fragments having binding specificity |
| JP7308191B2 (ja) * | 2017-10-18 | 2023-07-13 | フォーティ セブン， インコーポレイテッド | 抗ｃｄ４７剤ベースの卵巣癌療法 |
| EP3722312A4 (en) * | 2017-12-08 | 2021-07-21 | Hanx Biopharmaceutics, Inc | BISPECIFIC ANTI-PD-1 / CD47 ANTIBODIES AND ASSOCIATED APPLICATION |
| CN109053895B (zh) * | 2018-08-30 | 2020-06-09 | 中山康方生物医药有限公司 | 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途 |
| US12358987B2 (en) * | 2019-07-08 | 2025-07-15 | Nanjing GenScript Biotech Co., Ltd. | Anti-CD47/anti-PD-1 bispecific antibody, preparation method and use thereof |
| WO2021023117A1 (zh) * | 2019-08-02 | 2021-02-11 | 康方药业有限公司 | 抗ctla4-抗pd-1双特异性抗体及其用途 |
| BR112022002028A2 (pt) * | 2019-08-02 | 2022-04-12 | Cttq Akeso Shanghai Biomed Tech Co Ltd | Anticorpo anti-pd-1 e uso farmacêutico do mesmo |
| PH12022550489A1 (en) * | 2019-09-03 | 2022-12-12 | Akeso Biopharma Inc | Anti-cd47 monoclonal antibody and use thereof |
| PH12022551278A1 (en) * | 2019-11-25 | 2023-11-20 | Akeso Biopharma Inc | Anti-pd-1-anti-vegfa bispecific antibody, pharmaceutical composition and use thereof |
-
2022
- 2022-04-14 CN CN202210394792.XA patent/CN115192718A/zh active Pending
- 2022-04-14 CA CA3193664A patent/CA3193664A1/en active Pending
- 2022-04-14 MX MX2023010687A patent/MX2023010687A/es unknown
- 2022-04-14 WO PCT/CN2022/086890 patent/WO2022218384A1/zh not_active Ceased
- 2022-04-14 IL IL305363A patent/IL305363A/en unknown
- 2022-04-14 JP JP2023514956A patent/JP2024515396A/ja active Pending
- 2022-04-14 EP EP22787606.7A patent/EP4190816A4/en active Pending
- 2022-04-14 AU AU2022258273A patent/AU2022258273A1/en active Pending
- 2022-04-14 US US18/024,471 patent/US20240043531A1/en active Pending
- 2022-04-14 BR BR112023018450A patent/BR112023018450A2/pt unknown
- 2022-04-14 KR KR1020237031123A patent/KR20230170648A/ko active Pending
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