JP2023522730A5 - - Google Patents

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Publication number
JP2023522730A5
JP2023522730A5 JP2022564073A JP2022564073A JP2023522730A5 JP 2023522730 A5 JP2023522730 A5 JP 2023522730A5 JP 2022564073 A JP2022564073 A JP 2022564073A JP 2022564073 A JP2022564073 A JP 2022564073A JP 2023522730 A5 JP2023522730 A5 JP 2023522730A5
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JP
Japan
Prior art keywords
seq
amino acid
variable region
chain variable
acid sequence
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JP2022564073A
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English (en)
Japanese (ja)
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JP7763780B2 (ja
JP2023522730A (ja
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Priority claimed from PCT/CN2021/089059 external-priority patent/WO2021213475A1/zh
Publication of JP2023522730A publication Critical patent/JP2023522730A/ja
Publication of JP2023522730A5 publication Critical patent/JP2023522730A5/ja
Priority to JP2024218813A priority Critical patent/JP2025038088A/ja
Application granted granted Critical
Publication of JP7763780B2 publication Critical patent/JP7763780B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022564073A 2020-04-22 2021-04-22 抗cd73/抗pd-1二重特異性抗体及びその使用 Active JP7763780B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024218813A JP2025038088A (ja) 2020-04-22 2024-12-13 抗cd73/抗pd-1二重特異性抗体及びその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN202010324783.4 2020-04-22
CN202010324783 2020-04-22
CN202110270671 2021-03-12
CN202110270671.X 2021-03-12
PCT/CN2021/089059 WO2021213475A1 (zh) 2020-04-22 2021-04-22 抗cd73-抗pd-1双特异性抗体及其用途

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024218813A Division JP2025038088A (ja) 2020-04-22 2024-12-13 抗cd73/抗pd-1二重特異性抗体及びその使用

Publications (3)

Publication Number Publication Date
JP2023522730A JP2023522730A (ja) 2023-05-31
JP2023522730A5 true JP2023522730A5 (https=) 2023-07-10
JP7763780B2 JP7763780B2 (ja) 2025-11-04

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ID=78094648

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022564073A Active JP7763780B2 (ja) 2020-04-22 2021-04-22 抗cd73/抗pd-1二重特異性抗体及びその使用
JP2024218813A Pending JP2025038088A (ja) 2020-04-22 2024-12-13 抗cd73/抗pd-1二重特異性抗体及びその使用

Family Applications After (1)

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JP2024218813A Pending JP2025038088A (ja) 2020-04-22 2024-12-13 抗cd73/抗pd-1二重特異性抗体及びその使用

Country Status (13)

Country Link
US (1) US20230151111A1 (https=)
EP (1) EP4141033A4 (https=)
JP (2) JP7763780B2 (https=)
KR (1) KR20230004726A (https=)
CN (1) CN113527501B (https=)
AU (1) AU2021261803B2 (https=)
BR (1) BR112022021426A2 (https=)
CA (1) CA3176321A1 (https=)
IL (1) IL297432A (https=)
MX (1) MX2022013311A (https=)
PH (1) PH12022552785A1 (https=)
WO (1) WO2021213475A1 (https=)
ZA (1) ZA202211405B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112022002028A2 (pt) * 2019-08-02 2022-04-12 Cttq Akeso Shanghai Biomed Tech Co Ltd Anticorpo anti-pd-1 e uso farmacêutico do mesmo
CN120590533A (zh) * 2020-10-23 2025-09-05 中山康方生物医药有限公司 抗cd73的抗体及其用途
CN115073588B (zh) * 2021-03-12 2024-06-18 中山康方生物医药有限公司 提高含有免疫球蛋白Fc片段的药物的安全性的方法
JP2025512384A (ja) 2022-04-13 2025-04-17 ギリアード サイエンシーズ, インコーポレイテッド Trop-2発現がんを治療するための併用療法
KR20250026284A (ko) * 2022-06-22 2025-02-25 아케소 바이오파마, 인크. 약학 조성물 및 이의 용도
CN116813786B (zh) * 2023-08-03 2024-11-26 贝达药业股份有限公司 抗cd73抗体及其应用
WO2025137640A1 (en) 2023-12-22 2025-06-26 Gilead Sciences, Inc. Azaspiro wrn inhibitors

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
WO2011159877A2 (en) * 2010-06-18 2011-12-22 The Brigham And Women's Hospital, Inc. Bi-specific antibodies against tim-3 and pd-1 for immunotherapy in chronic immune conditions
GB2537445A (en) * 2014-11-10 2016-10-19 Medimmune Ltd Binding molecules specific for CD73 and uses thereof
GB2538120A (en) 2014-11-11 2016-11-09 Medimmune Ltd Therapeutic combinations comprising anti-CD73 antibodies and uses thereof
AU2015349878A1 (en) * 2014-11-21 2017-05-25 Bristol-Myers Squibb Company Antibodies against CD73 and uses thereof
US20190330335A1 (en) * 2015-10-06 2019-10-31 Alector Llc Anti-trem2 antibodies and methods of use thereof
KR20250057128A (ko) * 2015-12-30 2025-04-28 코디악 사이언시스 인코포레이티드 항체 및 이의 접합체
EP3423494A1 (en) * 2016-03-04 2019-01-09 Bristol-Myers Squibb Company Combination therapy with anti-cd73 antibodies
EP3494991A4 (en) * 2016-08-05 2020-07-29 Chugai Seiyaku Kabushiki Kaisha COMPOSITION FOR THE PROPHYLAXIS OR TREATMENT OF IL-8 RELATED DISEASES
CN106967172B (zh) * 2016-08-23 2019-01-08 康方药业有限公司 抗ctla4-抗pd-1 双功能抗体、其药物组合物及其用途
CN106977602B (zh) * 2016-08-23 2018-09-25 中山康方生物医药有限公司 一种抗pd1单克隆抗体、其药物组合物及其用途
KR20200096921A (ko) * 2017-11-06 2020-08-14 코버스 파마슈티칼스, 인크. 암 치료를 위한 아데노신 경로 억제제
EP3762030A4 (en) * 2018-03-09 2022-01-05 Phanes Therapeutics, Inc. ANTI-CD73 ANTIBODIES AND USES THEREOF
BR112020020826A2 (pt) * 2018-04-12 2021-01-19 Bristol-Myers Squibb Company Terapia de combinação anticâncer com anticorpo antagonista de cd73 e anticorpo antagonista do eixo pd-1/pd-l1
WO2020020307A1 (en) * 2018-07-25 2020-01-30 I-Mab Biopharma Co., Ltd. Anti-cd73 anti-pd-l1 bispecific antibodies
CN109053895B (zh) * 2018-08-30 2020-06-09 中山康方生物医药有限公司 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途
US20230159655A1 (en) * 2020-04-22 2023-05-25 Akeso Biopharma, Inc Anti-cd73 antibody and use thereof

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