JP2021523938A5 - - Google Patents
Info
- Publication number
- JP2021523938A5 JP2021523938A5 JP2021510564A JP2021510564A JP2021523938A5 JP 2021523938 A5 JP2021523938 A5 JP 2021523938A5 JP 2021510564 A JP2021510564 A JP 2021510564A JP 2021510564 A JP2021510564 A JP 2021510564A JP 2021523938 A5 JP2021523938 A5 JP 2021523938A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- mixture
- pharmaceutically acceptable
- neurosteroid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862667100P | 2018-05-04 | 2018-05-04 | |
| US62/667,100 | 2018-05-04 | ||
| US16/403,100 US20190337975A1 (en) | 2018-05-04 | 2019-05-03 | Neurosteroid derivatives and uses thereof |
| PCT/IB2019/000517 WO2019211668A2 (en) | 2018-05-04 | 2019-05-03 | Neurosteroid derivatives and uses thereof |
| US16/403,100 | 2019-05-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021523938A JP2021523938A (ja) | 2021-09-09 |
| JP2021523938A5 true JP2021523938A5 (enExample) | 2022-05-02 |
Family
ID=68384780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021510564A Pending JP2021523938A (ja) | 2018-05-04 | 2019-05-03 | 神経ステロイド誘導体およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20190337975A1 (enExample) |
| EP (1) | EP3788055A4 (enExample) |
| JP (1) | JP2021523938A (enExample) |
| CN (1) | CN112823164A (enExample) |
| AR (1) | AR116659A1 (enExample) |
| AU (1) | AU2019264032A1 (enExample) |
| CA (1) | CA3099089A1 (enExample) |
| PY (1) | PY1934080A (enExample) |
| TW (1) | TW202014192A (enExample) |
| UY (1) | UY38213A (enExample) |
| WO (1) | WO2019211668A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201606063RA (en) | 2012-01-23 | 2016-09-29 | Sage Therapeutics Inc | Neuroactive steroid formulations and methods of treating cns disorders |
| RS62761B1 (sr) | 2012-08-21 | 2022-01-31 | Sage Therapeutics Inc | Alopregnanolon za lečenje refraktornog epileptičkog statusa |
| WO2014169836A1 (en) | 2013-04-17 | 2014-10-23 | Sage Therapeutics, Inc. | 19-nor neuroactive steroids and methods of use thereof |
| SMT202100509T1 (it) | 2013-04-17 | 2021-11-12 | Sage Therapeutics Inc | Steroide di c21-n-pirazolile 19-nor c3,3-disostituito per l'uso in terapia |
| CN105579043B (zh) | 2013-08-23 | 2021-09-14 | 萨奇治疗股份有限公司 | 神经活性类固醇、组合物和其用途 |
| US10246482B2 (en) | 2014-06-18 | 2019-04-02 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| JOP20200195A1 (ar) | 2014-09-08 | 2017-06-16 | Sage Therapeutics Inc | سترويدات وتركيبات نشطة عصبياً، واستخداماتها |
| MY190408A (en) | 2014-10-16 | 2022-04-21 | Sage Therapeutics Inc | Compositions and methods for treating cns disorders |
| US20170233433A1 (en) | 2014-10-16 | 2017-08-17 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| LT3250210T (lt) | 2015-01-26 | 2021-04-12 | Sage Therapeutics, Inc. | Kompozicijos ir būdai, skirti gydyti cns sutrikimus |
| PH12018501923B1 (en) | 2016-03-08 | 2024-06-28 | Sage Therapeutics Inc | Neuroactive steroids, compositions, and uses thereof |
| CA3030420C (en) | 2016-07-11 | 2025-11-18 | Sage Therapeutics, Inc. | C7, C12 AND C16 SUBSTITUTED NEUROACTIVE STEROIDS AND ASSOCIATED METHODS OF USE |
| WO2018013613A1 (en) | 2016-07-11 | 2018-01-18 | Sage Therapeutics, Inc. | C17, c20, and c21 substituted neuroactive steroids and their methods of use |
| JP7670626B2 (ja) | 2019-05-31 | 2025-04-30 | セージ セラピューティクス， インコーポレイテッド | 神経刺激性ステロイド及びその組成物 |
| JP7810970B2 (ja) * | 2020-02-05 | 2026-02-04 | シーポート・セラピューティクス・インコーポレイテッド | 神経ステロイドの脂質プロドラッグ |
| WO2021174205A1 (en) * | 2020-02-27 | 2021-09-02 | Brii Biosciences, Inc. | Prodrugs of neuroactive steroids |
| IL315509A (en) * | 2022-03-18 | 2024-11-01 | Marinus Pharmaceuticals Inc | Genaxolone medication matrims |
| CN119632996A (zh) * | 2024-12-06 | 2025-03-18 | 北京华睿鼎信科技有限公司 | 神经甾体衍生物固体分散体及制备方法和应用、中枢神经系统障碍相关病症的治疗药物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB748846A (en) * | 1953-10-28 | 1956-05-09 | Vitamins Ltd | A process for the manufacture of pregnan-3(-a)-ol-20-one and derivatives thereof |
| US5232917A (en) * | 1987-08-25 | 1993-08-03 | University Of Southern California | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series |
| DK1038880T3 (da) * | 1994-02-14 | 2008-03-03 | Euro Celtique Sa | Androstaner og pregnaner til allosterisk modulering af GABA-receptor |
| WO2006010085A1 (en) * | 2004-07-09 | 2006-01-26 | Roxro Pharma, Inc. | Use of neurosteroids to treat neuropathic pain |
| WO2011120044A1 (en) * | 2010-03-26 | 2011-09-29 | Duke University | Conjugated neuroactive steroid compositions and methods of use |
| FR2973031B1 (fr) * | 2011-03-23 | 2013-11-29 | Univ Strasbourg | Derives de l'allopregnanolone et de l'epiallopregnanolone et leurs utilisations pour traiter un etat neuropathologique |
| US20170022245A1 (en) * | 2013-11-26 | 2017-01-26 | Biopharma Works | Ganaxolone derivatives for treatment of central nervous systems disorders |
| AU2018290348B2 (en) * | 2017-06-23 | 2024-04-04 | Ayikoe-Guy MENSAH-NYAGAN | Treatment of neuropsychiatric disorders with neurosteroids and analogues thereof |
| CN109666055A (zh) * | 2017-10-16 | 2019-04-23 | 张家口华健致远生物科技有限公司 | 调节中枢神经治疗抑郁症的化合物及其用途 |
-
2019
- 2019-05-03 UY UY38213A patent/UY38213A/es unknown
- 2019-05-03 CN CN201980033110.9A patent/CN112823164A/zh active Pending
- 2019-05-03 TW TW108115447A patent/TW202014192A/zh unknown
- 2019-05-03 AU AU2019264032A patent/AU2019264032A1/en not_active Abandoned
- 2019-05-03 US US16/403,100 patent/US20190337975A1/en not_active Abandoned
- 2019-05-03 PY PY201901934080A patent/PY1934080A/es unknown
- 2019-05-03 CA CA3099089A patent/CA3099089A1/en active Pending
- 2019-05-03 AR ARP190101187A patent/AR116659A1/es not_active Application Discontinuation
- 2019-05-03 EP EP19796480.2A patent/EP3788055A4/en not_active Withdrawn
- 2019-05-03 WO PCT/IB2019/000517 patent/WO2019211668A2/en not_active Ceased
- 2019-05-03 JP JP2021510564A patent/JP2021523938A/ja active Pending
-
2021
- 2021-08-02 US US17/392,004 patent/US20210363173A1/en not_active Abandoned
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