JP2021523119A5 - - Google Patents

Info

Publication number
JP2021523119A5
JP2021523119A5 JP2020561734A JP2020561734A JP2021523119A5 JP 2021523119 A5 JP2021523119 A5 JP 2021523119A5 JP 2020561734 A JP2020561734 A JP 2020561734A JP 2020561734 A JP2020561734 A JP 2020561734A JP 2021523119 A5 JP2021523119 A5 JP 2021523119A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
liposomes
disease
liposome
Prior art date
Application number
JP2020561734A
Other languages
English (en)
Japanese (ja)
Other versions
JP7355394B2 (ja
JP2021523119A (ja
JPWO2019213538A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/030625 external-priority patent/WO2019213538A1/en
Publication of JP2021523119A publication Critical patent/JP2021523119A/ja
Publication of JP2021523119A5 publication Critical patent/JP2021523119A5/ja
Publication of JPWO2019213538A5 publication Critical patent/JPWO2019213538A5/ja
Priority to JP2023148278A priority Critical patent/JP7555630B2/ja
Application granted granted Critical
Publication of JP7355394B2 publication Critical patent/JP7355394B2/ja
Priority to JP2024152342A priority patent/JP2024163254A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020561734A 2018-05-03 2019-05-03 カロテノイド組成物およびその使用 Active JP7355394B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023148278A JP7555630B2 (ja) 2018-05-03 2023-09-13 カロテノイド組成物およびその使用
JP2024152342A JP2024163254A (ja) 2018-05-03 2024-09-04 カロテノイド組成物およびその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862666699P 2018-05-03 2018-05-03
US62/666,699 2018-05-03
US201962809123P 2019-02-22 2019-02-22
US62/809,123 2019-02-22
PCT/US2019/030625 WO2019213538A1 (en) 2018-05-03 2019-05-03 Carotenoid compositions and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023148278A Division JP7555630B2 (ja) 2018-05-03 2023-09-13 カロテノイド組成物およびその使用

Publications (4)

Publication Number Publication Date
JP2021523119A JP2021523119A (ja) 2021-09-02
JP2021523119A5 true JP2021523119A5 (https=) 2022-05-13
JPWO2019213538A5 JPWO2019213538A5 (https=) 2022-05-13
JP7355394B2 JP7355394B2 (ja) 2023-10-03

Family

ID=68386961

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020561734A Active JP7355394B2 (ja) 2018-05-03 2019-05-03 カロテノイド組成物およびその使用
JP2023148278A Active JP7555630B2 (ja) 2018-05-03 2023-09-13 カロテノイド組成物およびその使用
JP2024152342A Pending JP2024163254A (ja) 2018-05-03 2024-09-04 カロテノイド組成物およびその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023148278A Active JP7555630B2 (ja) 2018-05-03 2023-09-13 カロテノイド組成物およびその使用
JP2024152342A Pending JP2024163254A (ja) 2018-05-03 2024-09-04 カロテノイド組成物およびその使用

Country Status (11)

Country Link
US (2) US12458597B2 (https=)
EP (2) EP4667017A3 (https=)
JP (3) JP7355394B2 (https=)
KR (2) KR20250159271A (https=)
CN (2) CN119185280A (https=)
AU (2) AU2019262189B2 (https=)
BR (1) BR112020022077A2 (https=)
CA (1) CA3098868A1 (https=)
ES (1) ES3063369T3 (https=)
MX (2) MX2020011662A (https=)
WO (1) WO2019213538A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180318414A1 (en) 2015-01-12 2018-11-08 Children's Medical Center Corporation Pro-Inflammatory and Adjuvant Functions of Toll-Like Receptor 4 Antagonists
CA3098868A1 (en) 2018-05-03 2019-11-07 L.E.A.F. Holdings Group Llc Carotenoid compositions and uses thereof
CA3157440A1 (en) * 2019-11-06 2021-05-14 Clet Niyikiza Carotenoid compositions and uses thereof
EP4061409A4 (en) * 2019-11-18 2023-12-27 Children's Medical Center Corporation Stimuli that hyperactivate resident dendritic cells for cancer immunotherapy
JP2023519958A (ja) * 2020-03-31 2023-05-15 ディフュージョン・ファーマシューティカルズ・エルエルシー ウイルス及び細菌誘導性呼吸器疾患の治療のための拡散増強化合物の使用
US20230134835A1 (en) * 2020-04-09 2023-05-04 L.E.A.F. Holdings Group Llc Methods of synthesizing carotenoids
WO2021207650A1 (en) * 2020-04-09 2021-10-14 L.E.A.F. Holdings Group Llc Trans-crocetin compositions and treatment regimens
WO2021207566A1 (en) * 2020-04-09 2021-10-14 L.E.A.F. Holdings Group Llc Carotenoid solutions and uses thereof
EP4132482A4 (en) * 2020-04-09 2024-05-08 L.E.A.F Holdings Group LLC TRANS-CROCETIN COMPOSITIONS AND TREATMENT SCHEMES
US20230270706A1 (en) * 2020-07-27 2023-08-31 L.E.A.F. Holdings Group Llc Trans-crocetin compositions and treatment regimens
US20230277494A1 (en) * 2020-07-27 2023-09-07 L.E.A.F. Holdings Group Llc Trans-crocetin compositions and treatment regimens
JP2023169444A (ja) * 2020-10-01 2023-11-30 株式会社Epsilon Molecular Engineering 標的タンパク質と結合し得る架橋ペプチド、当該架橋ペプチドの作製方法、及び当該架橋ペプチドを有効成分とする医薬組成物
WO2022150716A1 (en) * 2021-01-10 2022-07-14 Diffusion Pharmaceuticals Llc Methods of treating wounds and burns
WO2022240626A1 (en) * 2021-05-10 2022-11-17 L.E.A.F. Holdings Group Llc Methods and compositions for treating aging and chronic disease
WO2023029041A1 (zh) * 2021-09-06 2023-03-09 北京茵诺医药科技有限公司 靶向动脉粥样硬化脂质体纳米载体递送系统及其制备方法
CN114748461B (zh) * 2022-04-29 2023-03-21 合肥工业大学 一种藏红花酸制剂及其应用
CN114699396A (zh) * 2022-04-29 2022-07-05 合肥工业大学 藏红花酸作为抗疲劳成分在药物和食品方面的应用
US12128019B1 (en) 2023-06-15 2024-10-29 King Faisal University Nanocomposite including abscisic acid-loaded collagen nanoparticles
JP2025052190A (ja) 2023-09-25 2025-04-07 株式会社日立製作所 アンモニア合成触媒及びその製造方法
KR20250173014A (ko) 2024-05-30 2025-12-10 국립부경대학교 산학협력단 카로티노이드를 포함하는 근육 질환의 예방 및 치료용 약학 조성물
CN119081927B (zh) * 2024-08-28 2025-08-22 青岛日晟源作物营养有限公司 一株暹罗芽孢杆菌sl-k1及其菌根素提取物的制备方法和应用

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2840532A (en) * 1953-07-17 1958-06-24 Universal Oil Prod Co Alumina platinum catalyst and preparation thereof
US4699664A (en) * 1985-05-01 1987-10-13 Nestec S.A. Stabilized natural pigment complexes
US5795587A (en) 1995-01-23 1998-08-18 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
US6060511A (en) 1995-10-05 2000-05-09 Gainer; John L. Trans-sodium crocetinate, methods of making and methods of use thereof
US20030073640A1 (en) 1997-07-23 2003-04-17 Ribozyme Pharmaceuticals, Inc. Novel compositions for the delivery of negatively charged molecules
US6656498B1 (en) 1998-11-25 2003-12-02 Vanderbilt University Cationic liposomes for gene transfer
CA2437578A1 (en) 2001-02-13 2002-08-22 Rivka Cohen Carotenoid-loaded liposomes
EA200401111A1 (ru) 2002-02-25 2005-02-24 Диффьюжн Фармасьютикалз Ллс Биполярные соли транс-каротиноидов и их применение
US7759506B2 (en) * 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
WO2003101164A1 (en) 2002-05-23 2003-12-04 3M Innovative Properties Company Nanoparticle filled underfill
FR2840532B1 (fr) * 2002-06-11 2005-05-06 Ethypharm Sa Nanocapsules lipidiques furtives, procede de preparation et utilisation comme vecteur de principes(s) actif(s)
WO2003101184A2 (en) 2002-06-04 2003-12-11 California Institute Of Technology Carotenoid synthesis
EP2392562B1 (en) * 2002-07-29 2018-03-07 Cardax Pharma, Inc. Structural carotenoid analogs for the inhibition and amelioration of disease
GB0314624D0 (en) * 2003-06-23 2003-07-30 Advanced Bionutrition Europ Lt Inflammatory disease treatment
KR101017668B1 (ko) 2003-08-25 2011-02-25 디퓨젼 파마슈티컬즈 엘엘씨 양극성 트랜스 카로티노이드 염과 이들의 용도
CN1942178A (zh) * 2004-02-19 2007-04-04 奥克塞尔公司 用于治疗皮肤疾病的局部制剂
WO2006074416A1 (en) 2005-01-07 2006-07-13 Health Research Inc. 5-amino-4-imidazolecarboxamide riboside and its nucleobase as potentiators of antifolate transport and metabolism
JP5042863B2 (ja) 2005-02-14 2012-10-03 サーナ・セラピューティクス・インコーポレイテッド 生物学的に活性な分子をデリバリーするための脂質ナノ粒子系組成物および方法
US7404969B2 (en) 2005-02-14 2008-07-29 Sirna Therapeutics, Inc. Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
UA95903C2 (ru) 2005-02-24 2011-09-26 Дифьюжен Фармасьютикалз Ллк Транс-каротиноиды, их синтез, лекарственная форма и применение
CA2611137A1 (en) * 2005-03-23 2006-09-28 Cardax Pharmaceuticals, Inc. Water-dispersible carotenoids, including analogs and derivatives
AU2006251391B2 (en) * 2005-05-23 2011-10-06 Phares Pharmaceutical Research N.V. Direct dissolution
US20080221377A1 (en) 2006-06-16 2008-09-11 Lockwood Samuel F Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates
US20100015218A1 (en) 2007-02-16 2010-01-21 Vasant Jadhav Compositions and methods for potentiated activity of biologically active molecules
US20080213352A1 (en) * 2007-03-02 2008-09-04 Luna Innovations Incorporated Liposome carriers for in vivo delivery of fullerenes
JP5191764B2 (ja) * 2007-03-30 2013-05-08 理研ビタミン株式会社 睡眠改善剤
US20110224447A1 (en) 2008-08-18 2011-09-15 Bowman Keith A Novel Lipid Nanoparticles and Novel Components for Delivery of Nucleic Acids
WO2010080724A1 (en) 2009-01-12 2010-07-15 Merck Sharp & Dohme Corp. Novel lipid nanoparticles and novel components for delivery of nucleic acids
JP2009179628A (ja) 2009-01-16 2009-08-13 Tsujido Chemical Corp 養毛・育毛剤
US8569256B2 (en) 2009-07-01 2013-10-29 Protiva Biotherapeutics, Inc. Cationic lipids and methods for the delivery of therapeutic agents
ES2613498T3 (es) 2009-07-01 2017-05-24 Protiva Biotherapeutics Inc. Nuevas formulaciones de lípidos para el suministro de agentes terapéuticos a tumores sólidos
EP2467357B1 (en) 2009-08-20 2016-03-30 Sirna Therapeutics, Inc. Novel cationic lipids with various head groups for oligonucleotide delivery
US8591555B2 (en) * 2009-08-31 2013-11-26 Warsaw Orthopedic, Inc. System with integral locking mechanism
US20120253032A1 (en) 2009-10-08 2012-10-04 Merck Sharp & Dohme Corporation Novel cationic lipids with short lipid chains for oligonucleotide delivery
US20130116419A1 (en) 2010-01-22 2013-05-09 Daniel Zewge Post-synthetic chemical modification of rna at the 2'-position of the ribose ring via "click" chemistry
CN101811956B (zh) * 2010-04-15 2013-04-17 施冬云 反式西红花酸的制备方法
US8802863B2 (en) 2010-05-24 2014-08-12 Sirna Therapeutics, Inc. Amino alcohol cationic lipids for oligonucleotide delivery
KR101891357B1 (ko) * 2010-06-02 2018-08-24 디퓨젼 파마슈티컬즈 엘엘씨 양극성 트랜스 카로티노이드의 경구용 제형
US8748667B2 (en) 2010-06-04 2014-06-10 Sirna Therapeutics, Inc. Low molecular weight cationic lipids for oligonucleotide delivery
CA2801523C (en) 2010-07-30 2021-08-03 Curevac Gmbh Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation
ES2888231T3 (es) 2010-09-20 2022-01-03 Sirna Therapeutics Inc Lípidos catiónicos de bajo peso molecular para el suministro de oligonucleótidos
EP2621480B1 (en) 2010-09-30 2018-08-15 Sirna Therapeutics, Inc. Low molecular weight cationic lipids for oligonucleotide delivery
JP2013545727A (ja) 2010-10-21 2013-12-26 メルク・シャープ・アンド・ドーム・コーポレーション オリゴヌクレオチド送達用の新規低分子量カチオン性脂質
EP2635265B1 (en) 2010-11-05 2018-04-04 Sirna Therapeutics, Inc. Novel low molecular weight cyclic amine containing cationic lipids for oligonucleotide delivery
GB201101669D0 (en) 2011-01-31 2011-03-16 Ip Science Ltd Carotenoid particles and uses thereof
EP3354644A1 (en) 2011-06-08 2018-08-01 Translate Bio, Inc. Cleavable lipids
CN103183603A (zh) 2011-12-30 2013-07-03 江苏天晟药业有限公司 藏红花酸有机胺盐及其制备方法
JP2015520194A (ja) * 2012-06-07 2015-07-16 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 薬物標的指向化のためのナノ療法
US9211298B2 (en) 2012-11-16 2015-12-15 Song Gao Compositions containing enriched natural crocin and/or crocetin, and their therapeutic or nutraceutical uses
EP3217970A4 (en) 2014-11-10 2018-07-18 Del Mar Pharmaceuticals Dianhydrogalactitol together with radiation to treat non-small-cell carcinoma of the lung and glioblastoma multiforme
FR3035589B1 (fr) 2015-04-30 2019-12-13 Biophytis Composition pour la protection des cellules de l'epithelium pigmentaire retinien
US11185523B2 (en) * 2016-03-24 2021-11-30 Diffusion Pharmaceuticals Llc Use of bipolar trans carotenoids with chemotherapy and radiotherapy for treatment of cancer
CN105935363B (zh) * 2016-04-29 2017-03-08 暨南大学 组合物、藏红花色素类活性部位及其用途
CN107753427B (zh) 2016-08-18 2022-01-14 上海交通大学 一种全反式维甲酸脂质体制剂及其制备与应用
CA3098868A1 (en) 2018-05-03 2019-11-07 L.E.A.F. Holdings Group Llc Carotenoid compositions and uses thereof
CA3157440A1 (en) * 2019-11-06 2021-05-14 Clet Niyikiza Carotenoid compositions and uses thereof
WO2021207650A1 (en) 2020-04-09 2021-10-14 L.E.A.F. Holdings Group Llc Trans-crocetin compositions and treatment regimens
EP4132482A4 (en) 2020-04-09 2024-05-08 L.E.A.F Holdings Group LLC TRANS-CROCETIN COMPOSITIONS AND TREATMENT SCHEMES
WO2021207566A1 (en) 2020-04-09 2021-10-14 L.E.A.F. Holdings Group Llc Carotenoid solutions and uses thereof
US20230134835A1 (en) 2020-04-09 2023-05-04 L.E.A.F. Holdings Group Llc Methods of synthesizing carotenoids
US20230277494A1 (en) 2020-07-27 2023-09-07 L.E.A.F. Holdings Group Llc Trans-crocetin compositions and treatment regimens
US20230270706A1 (en) 2020-07-27 2023-08-31 L.E.A.F. Holdings Group Llc Trans-crocetin compositions and treatment regimens

Similar Documents

Publication Publication Date Title
JP2021523119A5 (https=)
JPWO2019213538A5 (https=)
JP2025072362A5 (https=)
JP2019524885A5 (https=)
JP2019524802A5 (https=)
JP2021513550A5 (https=)
US20220211878A1 (en) Cross-linked polymer modified nanoparticles
JP2021512895A5 (https=)
JP2021513528A5 (https=)
JP2021513531A5 (https=)
JP2021514357A5 (https=)
JP2021513529A5 (https=)
AU2019262189B2 (en) Carotenoid compositions and uses thereof
JPWO2019157138A5 (https=)
JP2021513533A5 (https=)
CN116171150A (zh) 冻干脂质纳米颗粒的方法
JPWO2019157145A5 (https=)
JP2012503603A5 (https=)
Lenders et al. Modulation of engineered nanomaterial interactions with organ barriers for enhanced drug transport
JP2017505104A5 (https=)
JPWO2019160735A5 (https=)
JP2019533645A5 (https=)
JPWO2019157125A5 (https=)
JPWO2019157120A5 (https=)
JP2009512696A (ja) 標的化イムノリポソームの調製法