JP7355394B2 - カロテノイド組成物およびその使用 - Google Patents

カロテノイド組成物およびその使用 Download PDF

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Publication number
JP7355394B2
JP7355394B2 JP2020561734A JP2020561734A JP7355394B2 JP 7355394 B2 JP7355394 B2 JP 7355394B2 JP 2020561734 A JP2020561734 A JP 2020561734A JP 2020561734 A JP2020561734 A JP 2020561734A JP 7355394 B2 JP7355394 B2 JP 7355394B2
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Japan
Prior art keywords
liposome
liposomes
pharmaceutical composition
ionizable
carotenoid
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JP2020561734A
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Japanese (ja)
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JP2021523119A5 (https=
JP2021523119A (ja
JPWO2019213538A5 (https=
Inventor
ニイキザ，クレト
モヨ，ヴィクター，マンドラ
ゲン，ボリン
シュー，ジェンホン
カリファ，カニズ
キム，グワンソン
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LEAF Holdings Group LLC
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LEAF Holdings Group LLC
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Publication of JP2021523119A publication Critical patent/JP2021523119A/ja
Publication of JP2021523119A5 publication Critical patent/JP2021523119A5/ja
Publication of JPWO2019213538A5 publication Critical patent/JPWO2019213538A5/ja
Priority to JP2023148278A priority Critical patent/JP7555630B2/ja
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Publication of JP7355394B2 publication Critical patent/JP7355394B2/ja
Priority to JP2024152342A priority patent/JP2024163254A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
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    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
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    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
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    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
JP2020561734A 2018-05-03 2019-05-03 カロテノイド組成物およびその使用 Active JP7355394B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023148278A JP7555630B2 (ja) 2018-05-03 2023-09-13 カロテノイド組成物およびその使用
JP2024152342A JP2024163254A (ja) 2018-05-03 2024-09-04 カロテノイド組成物およびその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862666699P 2018-05-03 2018-05-03
US62/666,699 2018-05-03
US201962809123P 2019-02-22 2019-02-22
US62/809,123 2019-02-22
PCT/US2019/030625 WO2019213538A1 (en) 2018-05-03 2019-05-03 Carotenoid compositions and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023148278A Division JP7555630B2 (ja) 2018-05-03 2023-09-13 カロテノイド組成物およびその使用

Publications (4)

Publication Number Publication Date
JP2021523119A JP2021523119A (ja) 2021-09-02
JP2021523119A5 JP2021523119A5 (https=) 2022-05-13
JPWO2019213538A5 JPWO2019213538A5 (https=) 2022-05-13
JP7355394B2 true JP7355394B2 (ja) 2023-10-03

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JP2020561734A Active JP7355394B2 (ja) 2018-05-03 2019-05-03 カロテノイド組成物およびその使用
JP2023148278A Active JP7555630B2 (ja) 2018-05-03 2023-09-13 カロテノイド組成物およびその使用
JP2024152342A Pending JP2024163254A (ja) 2018-05-03 2024-09-04 カロテノイド組成物およびその使用

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JP2023148278A Active JP7555630B2 (ja) 2018-05-03 2023-09-13 カロテノイド組成物およびその使用
JP2024152342A Pending JP2024163254A (ja) 2018-05-03 2024-09-04 カロテノイド組成物およびその使用

Country Status (11)

Country Link
US (2) US12458597B2 (https=)
EP (2) EP4667017A3 (https=)
JP (3) JP7355394B2 (https=)
KR (2) KR20250159271A (https=)
CN (2) CN119185280A (https=)
AU (2) AU2019262189B2 (https=)
BR (1) BR112020022077A2 (https=)
CA (1) CA3098868A1 (https=)
ES (1) ES3063369T3 (https=)
MX (2) MX2020011662A (https=)
WO (1) WO2019213538A1 (https=)

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US20180318414A1 (en) 2015-01-12 2018-11-08 Children's Medical Center Corporation Pro-Inflammatory and Adjuvant Functions of Toll-Like Receptor 4 Antagonists
CA3098868A1 (en) 2018-05-03 2019-11-07 L.E.A.F. Holdings Group Llc Carotenoid compositions and uses thereof
CA3157440A1 (en) * 2019-11-06 2021-05-14 Clet Niyikiza Carotenoid compositions and uses thereof
EP4061409A4 (en) * 2019-11-18 2023-12-27 Children's Medical Center Corporation Stimuli that hyperactivate resident dendritic cells for cancer immunotherapy
JP2023519958A (ja) * 2020-03-31 2023-05-15 ディフュージョン・ファーマシューティカルズ・エルエルシー ウイルス及び細菌誘導性呼吸器疾患の治療のための拡散増強化合物の使用
US20230134835A1 (en) * 2020-04-09 2023-05-04 L.E.A.F. Holdings Group Llc Methods of synthesizing carotenoids
WO2021207650A1 (en) * 2020-04-09 2021-10-14 L.E.A.F. Holdings Group Llc Trans-crocetin compositions and treatment regimens
WO2021207566A1 (en) * 2020-04-09 2021-10-14 L.E.A.F. Holdings Group Llc Carotenoid solutions and uses thereof
EP4132482A4 (en) * 2020-04-09 2024-05-08 L.E.A.F Holdings Group LLC TRANS-CROCETIN COMPOSITIONS AND TREATMENT SCHEMES
US20230270706A1 (en) * 2020-07-27 2023-08-31 L.E.A.F. Holdings Group Llc Trans-crocetin compositions and treatment regimens
US20230277494A1 (en) * 2020-07-27 2023-09-07 L.E.A.F. Holdings Group Llc Trans-crocetin compositions and treatment regimens
JP2023169444A (ja) * 2020-10-01 2023-11-30 株式会社Epsilon Molecular Engineering 標的タンパク質と結合し得る架橋ペプチド、当該架橋ペプチドの作製方法、及び当該架橋ペプチドを有効成分とする医薬組成物
WO2022150716A1 (en) * 2021-01-10 2022-07-14 Diffusion Pharmaceuticals Llc Methods of treating wounds and burns
WO2022240626A1 (en) * 2021-05-10 2022-11-17 L.E.A.F. Holdings Group Llc Methods and compositions for treating aging and chronic disease
WO2023029041A1 (zh) * 2021-09-06 2023-03-09 北京茵诺医药科技有限公司 靶向动脉粥样硬化脂质体纳米载体递送系统及其制备方法
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