KR102877117B1 - 카로티노이드 조성물 및 이의 용도 - Google Patents

카로티노이드 조성물 및 이의 용도

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Publication number
KR102877117B1
KR102877117B1 KR1020207034818A KR20207034818A KR102877117B1 KR 102877117 B1 KR102877117 B1 KR 102877117B1 KR 1020207034818 A KR1020207034818 A KR 1020207034818A KR 20207034818 A KR20207034818 A KR 20207034818A KR 102877117 B1 KR102877117 B1 KR 102877117B1
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South Korea
Prior art keywords
delete delete
liposome
ionizable
carotenoid
liposomes
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KR1020207034818A
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Korean (ko)
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KR20210005244A (ko
Inventor
클레트 니이키자
빅터 만들라 모요
볼린 겅
정홍 쑤
카니즈 칼리파
광성 김
Original Assignee
엘.이.에이.에프. 홀딩스 그룹 엘엘씨.
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Priority to KR1020257035390A priority Critical patent/KR20250159271A/ko
Publication of KR20210005244A publication Critical patent/KR20210005244A/ko
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/01Hydrocarbons
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • A61K31/015Hydrocarbons carbocyclic
    • AHUMAN NECESSITIES
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    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
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    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203Retinoic acids ; Salts thereof
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    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
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    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
KR1020207034818A 2018-05-03 2019-05-03 카로티노이드 조성물 및 이의 용도 Active KR102877117B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020257035390A KR20250159271A (ko) 2018-05-03 2019-05-03 카로티노이드 조성물 및 이의 용도

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862666699P 2018-05-03 2018-05-03
US62/666,699 2018-05-03
US201962809123P 2019-02-22 2019-02-22
US62/809,123 2019-02-22
PCT/US2019/030625 WO2019213538A1 (en) 2018-05-03 2019-05-03 Carotenoid compositions and uses thereof

Related Child Applications (1)

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Publications (2)

Publication Number Publication Date
KR20210005244A KR20210005244A (ko) 2021-01-13
KR102877117B1 true KR102877117B1 (ko) 2025-10-27

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KR1020257035390A Pending KR20250159271A (ko) 2018-05-03 2019-05-03 카로티노이드 조성물 및 이의 용도

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US (2) US12458597B2 (https=)
EP (2) EP4667017A3 (https=)
JP (3) JP7355394B2 (https=)
KR (2) KR102877117B1 (https=)
CN (2) CN119185280A (https=)
AU (2) AU2019262189B2 (https=)
BR (1) BR112020022077A2 (https=)
CA (1) CA3098868A1 (https=)
ES (1) ES3063369T3 (https=)
MX (2) MX2020011662A (https=)
WO (1) WO2019213538A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018501322A (ja) 2015-01-12 2018-01-18 チルドレンズ メディカル センター コーポレーション トール様受容体4アンタゴニストの炎症促進性およびアジュバント機能
JP7355394B2 (ja) 2018-05-03 2023-10-03 エル.イー.エー.エフ. ホールディングス グループ エルエルシー カロテノイド組成物およびその使用
WO2021091862A1 (en) * 2019-11-06 2021-05-14 L.E.A.F. Holdings Group Llc Carotenoid compositions and uses thereof
CN114980919B (zh) * 2019-11-18 2026-04-14 儿童医学中心公司 过度活化驻留树突状细胞的刺激物用于癌症免疫疗法
EP4125857A4 (en) * 2020-03-31 2024-04-17 Diffusion Pharmaceuticals LLC USE OF DIFFUSION ENHANCEMENT COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASE INDUCED BY VIRUSES AND BACTERIA
WO2021207566A1 (en) * 2020-04-09 2021-10-14 L.E.A.F. Holdings Group Llc Carotenoid solutions and uses thereof
US20230134835A1 (en) * 2020-04-09 2023-05-04 L.E.A.F. Holdings Group Llc Methods of synthesizing carotenoids
WO2021207650A1 (en) * 2020-04-09 2021-10-14 L.E.A.F. Holdings Group Llc Trans-crocetin compositions and treatment regimens
WO2021207690A1 (en) * 2020-04-09 2021-10-14 L.E.A.F. Holdings Group Llc Trans-crocetin compositions and treatment regimens
US20230277494A1 (en) * 2020-07-27 2023-09-07 L.E.A.F. Holdings Group Llc Trans-crocetin compositions and treatment regimens
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JP2023169444A (ja) * 2020-10-01 2023-11-30 株式会社Epsilon Molecular Engineering 標的タンパク質と結合し得る架橋ペプチド、当該架橋ペプチドの作製方法、及び当該架橋ペプチドを有効成分とする医薬組成物
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