JP2021521104A5 - - Google Patents

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Publication number
JP2021521104A5
JP2021521104A5 JP2020554437A JP2020554437A JP2021521104A5 JP 2021521104 A5 JP2021521104 A5 JP 2021521104A5 JP 2020554437 A JP2020554437 A JP 2020554437A JP 2020554437 A JP2020554437 A JP 2020554437A JP 2021521104 A5 JP2021521104 A5 JP 2021521104A5
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JP
Japan
Prior art keywords
compound according
alkyl
cycloalkyl
pharmaceutically acceptable
disease
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JP2020554437A
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English (en)
Japanese (ja)
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JP2021521104A (ja
JP7383635B2 (ja
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Priority claimed from PCT/US2019/026054 external-priority patent/WO2019195720A1/en
Publication of JP2021521104A publication Critical patent/JP2021521104A/ja
Publication of JP2021521104A5 publication Critical patent/JP2021521104A5/ja
Priority to JP2023190466A priority Critical patent/JP7720376B2/ja
Application granted granted Critical
Publication of JP7383635B2 publication Critical patent/JP7383635B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020554437A 2018-04-06 2019-04-05 置換されたベンゾフラン、ベンゾピロール、ベンゾチオフェン、及び構造的に関連する補体阻害剤 Active JP7383635B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023190466A JP7720376B2 (ja) 2018-04-06 2023-11-08 置換されたベンゾフラン、ベンゾピロール、ベンゾチオフェン、及び構造的に関連する補体阻害剤

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862654108P 2018-04-06 2018-04-06
US62/654,108 2018-04-06
PCT/US2019/026054 WO2019195720A1 (en) 2018-04-06 2019-04-05 Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023190466A Division JP7720376B2 (ja) 2018-04-06 2023-11-08 置換されたベンゾフラン、ベンゾピロール、ベンゾチオフェン、及び構造的に関連する補体阻害剤

Publications (3)

Publication Number Publication Date
JP2021521104A JP2021521104A (ja) 2021-08-26
JP2021521104A5 true JP2021521104A5 (https=) 2022-08-09
JP7383635B2 JP7383635B2 (ja) 2023-11-20

Family

ID=68101457

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020554437A Active JP7383635B2 (ja) 2018-04-06 2019-04-05 置換されたベンゾフラン、ベンゾピロール、ベンゾチオフェン、及び構造的に関連する補体阻害剤
JP2023190466A Active JP7720376B2 (ja) 2018-04-06 2023-11-08 置換されたベンゾフラン、ベンゾピロール、ベンゾチオフェン、及び構造的に関連する補体阻害剤

Family Applications After (1)

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JP2023190466A Active JP7720376B2 (ja) 2018-04-06 2023-11-08 置換されたベンゾフラン、ベンゾピロール、ベンゾチオフェン、及び構造的に関連する補体阻害剤

Country Status (34)

Country Link
US (7) US11021458B2 (https=)
EP (3) EP3939658B1 (https=)
JP (2) JP7383635B2 (https=)
KR (1) KR102936604B1 (https=)
CN (2) CN117164499A (https=)
AR (1) AR115033A1 (https=)
AU (2) AU2019247471B2 (https=)
BR (1) BR112020019183A2 (https=)
CL (2) CL2020002578A1 (https=)
CO (1) CO2020013840A2 (https=)
CY (1) CY1124510T1 (https=)
DK (2) DK3687506T3 (https=)
EA (1) EA202092383A1 (https=)
ES (2) ES2891123T3 (https=)
FI (1) FI3939658T3 (https=)
HR (2) HRP20241536T1 (https=)
HU (2) HUE055307T2 (https=)
IL (2) IL305879B2 (https=)
LT (2) LT3687506T (https=)
MA (2) MA57412B1 (https=)
MD (2) MD3687506T2 (https=)
MX (2) MX2020010508A (https=)
PE (1) PE20210398A1 (https=)
PH (1) PH12020551589A1 (https=)
PL (2) PL3687506T3 (https=)
PT (2) PT3687506T (https=)
PY (1) PY1927283A (https=)
RS (2) RS62370B1 (https=)
SG (1) SG11202008972WA (https=)
SI (2) SI3939658T1 (https=)
SM (2) SMT202400528T1 (https=)
TW (2) TWI873092B (https=)
UY (1) UY38174A (https=)
WO (1) WO2019195720A1 (https=)

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PY2062527A (es) * 2019-10-09 2021-09-23 Biocryst Pharm Inc Inhibidores del factor d del complemento para administración oral
CN115362162A (zh) 2020-02-20 2022-11-18 艾其林医药公司 用于治疗补体因子d介导的障碍的杂芳基化合物
AR121715A1 (es) * 2020-04-03 2022-06-29 Biocryst Pharm Inc Pirrolopirimidinaminas como inhibidores del sistema del complemento
US20230391758A1 (en) * 2020-09-18 2023-12-07 Merck Sharp & Dohme Llc Modified benzofuran-carboxamides as glucosylceramide synthase inhibitors
TW202304890A (zh) * 2021-04-14 2023-02-01 美商百歐克斯製藥公司 Klk5雙環雜芳香族抑制劑
TW202330489A (zh) * 2021-10-21 2023-08-01 大陸商江蘇恆瑞醫藥股份有限公司 稠合環類化合物、其製備方法及其在醫藥上的應用
AR129422A1 (es) * 2022-05-25 2024-08-21 Univ Leuven Kath Nuevos derivados para tratar trastornos mediados por trpm3
EP4622643A1 (en) * 2022-11-22 2025-10-01 Maze Therapeutics, Inc. Inhibitors of solute carrier family 6a member 19 (slc6a19) and methods of use thereof
TW202434204A (zh) * 2023-01-06 2024-09-01 美商百歐克斯製藥公司 用於治療補體介導之疾病之口服劑型及口服給藥方案
KR102925481B1 (ko) * 2023-09-05 2026-02-10 광주과학기술원 신규 화합물 및 이의 건선 치료 용도
WO2025080823A1 (en) 2023-10-11 2025-04-17 Regeneron Pharmaceuticals, Inc. Treatment of macular degeneration with complement factor d (cfd) inhibitors
CN119504834B (zh) * 2024-11-21 2025-10-17 南开大学 一种以含硅基团为疏水标签的pd-l1蛋白降解剂及其制备方法、药物组合物和应用

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KR20220041846A (ko) 2019-07-31 2022-04-01 바이오크리스트파마슈티컬즈,인코포레이티드 경구 보체 인자 d 억제제에 대한 투약 요법

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