SI3687506T1 - Substituirani benzofuran, benzopirol, benzotiofen in strukturno povezani inhibitorji dopolnitve - Google Patents

Substituirani benzofuran, benzopirol, benzotiofen in strukturno povezani inhibitorji dopolnitve

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Publication number
SI3687506T1
SI3687506T1 SI201930099T SI201930099T SI3687506T1 SI 3687506 T1 SI3687506 T1 SI 3687506T1 SI 201930099 T SI201930099 T SI 201930099T SI 201930099 T SI201930099 T SI 201930099T SI 3687506 T1 SI3687506 T1 SI 3687506T1
Authority
SI
Slovenia
Prior art keywords
benzopyrrole
benzothiophene
structurally related
complement inhibitors
substituted benzofuran
Prior art date
Application number
SI201930099T
Other languages
English (en)
Inventor
Pravin L. Kotian
Yarlagadda S. Babu
Weihe Zhang
peng-cheng Lu
Minwan Wu
Wei Lv
Trung Xuan Nguyen
zhao Dang
Venkat R. Chintareddy
V. Satish Kumar
Krishnan Raman
Original Assignee
Biocryst Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocryst Pharmaceuticals, Inc. filed Critical Biocryst Pharmaceuticals, Inc.
Publication of SI3687506T1 publication Critical patent/SI3687506T1/sl

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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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SI201930099T 2018-04-06 2019-04-05 Substituirani benzofuran, benzopirol, benzotiofen in strukturno povezani inhibitorji dopolnitve SI3687506T1 (sl)

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