JP2021519315A5 - - Google Patents
Info
- Publication number
- JP2021519315A5 JP2021519315A5 JP2020551992A JP2020551992A JP2021519315A5 JP 2021519315 A5 JP2021519315 A5 JP 2021519315A5 JP 2020551992 A JP2020551992 A JP 2020551992A JP 2020551992 A JP2020551992 A JP 2020551992A JP 2021519315 A5 JP2021519315 A5 JP 2021519315A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- rna virus
- condition
- keratitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023035224A JP7745584B2 (ja) | 2018-03-27 | 2023-03-08 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
| JP2025076718A JP2025118771A (ja) | 2018-03-27 | 2025-05-02 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862648585P | 2018-03-27 | 2018-03-27 | |
| US62/648,585 | 2018-03-27 | ||
| US201862693021P | 2018-07-02 | 2018-07-02 | |
| US62/693,021 | 2018-07-02 | ||
| PCT/US2019/023977 WO2019191026A2 (en) | 2018-03-27 | 2019-03-26 | Methods for the use of 5'-adenosine diphosphate ribose (adpr) |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023035224A Division JP7745584B2 (ja) | 2018-03-27 | 2023-03-08 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021519315A JP2021519315A (ja) | 2021-08-10 |
| JP2021519315A5 true JP2021519315A5 (enExample) | 2022-04-01 |
| JP7242696B2 JP7242696B2 (ja) | 2023-03-20 |
Family
ID=66647439
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020551992A Active JP7242696B2 (ja) | 2018-03-27 | 2019-03-26 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
| JP2023035224A Active JP7745584B2 (ja) | 2018-03-27 | 2023-03-08 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
| JP2025076718A Pending JP2025118771A (ja) | 2018-03-27 | 2025-05-02 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023035224A Active JP7745584B2 (ja) | 2018-03-27 | 2023-03-08 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
| JP2025076718A Pending JP2025118771A (ja) | 2018-03-27 | 2025-05-02 | ５’－アデノシン二リン酸リボース（ａｄｐｒ）の使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US10946034B2 (enExample) |
| EP (2) | EP4226971A1 (enExample) |
| JP (3) | JP7242696B2 (enExample) |
| ES (1) | ES2949441T3 (enExample) |
| WO (1) | WO2019191026A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102622656B1 (ko) | 2016-02-18 | 2024-01-10 | 인버사, 인크. | 5'-아데노신 디포스페이트 리보오스 (adpr)의 사용 방법 |
| US10946034B2 (en) | 2018-03-27 | 2021-03-16 | Invirsa, Inc. | Methods for the use of 5′-adenosine diphosphate ribose (ADPR) |
| CN111714619B (zh) * | 2020-07-15 | 2023-03-14 | 上海市浦东新区人民医院 | 成纤维生长因子6在制备缓解非酒精性脂肪性肝炎肝损伤的药物中的应用 |
| CN112972453B (zh) * | 2021-03-05 | 2022-04-15 | 中国人民解放军军事科学院军事医学研究院 | MDL-800在制备抑制SARS-CoV-2病毒易感性药物中的应用 |
| KR102789553B1 (ko) * | 2021-09-07 | 2025-04-03 | 주식회사 펄스인마이어스 | 방사선 및/또는 항암 치료 보조 요법으로 아데노신 디포스페이트 리보오스의 활용 |
| WO2025122455A1 (en) * | 2023-12-04 | 2025-06-12 | Invirsa, Inc. | Methods for the use of 5'-adenosine diphosphate ribose (adpr) for vegf modulation |
| WO2025259632A1 (en) * | 2024-06-12 | 2025-12-18 | Sirtsei Pharmaceuticals, Inc. | Compositions and methods for treating retinal diseases or conditions |
| WO2026073064A1 (en) * | 2024-09-30 | 2026-04-02 | Invirsa, Inc. | 5'-adenosine diphosphate ribose (adpr) for use in improving visual acuity |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04273826A (ja) * | 1991-02-27 | 1992-09-30 | Dainippon Ink & Chem Inc | 抗ｒｓウイルス剤 |
| EP0618214A1 (en) | 1993-04-01 | 1994-10-05 | Merrell Dow Pharmaceuticals Inc. | Unsaturated phosphonate derivatives of purines and pyrimidines |
| JPH07247210A (ja) | 1994-03-09 | 1995-09-26 | Sunstar Inc | 口腔用組成物 |
| WO1999012951A1 (en) | 1997-09-11 | 1999-03-18 | Oxigene, Inc. | Uses of nicotinamide adenine dinucleotide and its analogs for treatment of malignant and infectious diseases |
| DE60015734D1 (de) | 1999-02-26 | 2004-12-16 | Inspire Pharmaceuticals Durham | Verwendung von dinukleotidtriphosphaten, cytidindiphosphaten und adenindiphosphaten zur herstellung einer pharmazeutischen zubereitung zur förderung der schleimauthydratation |
| WO2000077179A2 (en) | 1999-06-16 | 2000-12-21 | Icos Corporation | Human poly(adp-ribose) polymerase 2 materials and methods |
| US6528042B1 (en) | 1999-10-08 | 2003-03-04 | Galileo Laboratories, Inc. | Compositions of flavonoids for use as cytoprotectants and methods of making and using them |
| US7115585B2 (en) | 2000-08-21 | 2006-10-03 | Inspire Pharmaceuticals, Inc. | Compositions for treating epithelial and retinal tissue diseases |
| WO2003011885A1 (en) | 2001-07-25 | 2003-02-13 | Celltech R & D Limited | Non-natural carbon-linked nucleotides and dinucleotides |
| US20030236217A1 (en) | 2002-05-21 | 2003-12-25 | Shalwitz Robert A. | Treatment of mucositis |
| JP2005089450A (ja) | 2003-08-11 | 2005-04-07 | Fujisawa Pharmaceut Co Ltd | Ｒｓウィルスによる感染症の予防または治療剤 |
| US20070212395A1 (en) | 2006-03-08 | 2007-09-13 | Allergan, Inc. | Ocular therapy using sirtuin-activating agents |
| US20050276762A1 (en) | 2004-06-15 | 2005-12-15 | Tapas Das | Topical compositions containing 5'-adenosine-diphosphate ribose |
| CA2609549A1 (en) | 2005-05-25 | 2006-11-30 | Sirtris Pharmaceuticals, Inc. | Treatment of eye disorders with sirtuin modulators |
| WO2007054814A1 (en) | 2005-11-14 | 2007-05-18 | Centre National De La Recherche Scientifique - Cnrs | Inhibitors of parp activity and uses thereof |
| WO2008154129A1 (en) | 2007-06-08 | 2008-12-18 | Bausch & Lomb Incorporated | Pharmaceutical compositions and method for treating, reducing, ameliorating, alleviating, or preventing dry eye |
| US20110217262A1 (en) | 2010-03-05 | 2011-09-08 | Kornfield Julia A | Treatment of Ocular Surface Disorders by Increasing Conjunctival Vascular Permeability |
| AU2011251622A1 (en) | 2010-05-10 | 2012-12-20 | Radikal Therapeutics Inc. | Lipoic acid and nitroxide derivatives and uses thereof |
| JP6072009B2 (ja) | 2011-05-12 | 2017-02-01 | フォーサイト・バイオセラピューティクス・インコーポレーテッド | ステロイド又は非ステロイド性抗炎症薬のある安定なポビドンヨード組成物 |
| US20160287622A1 (en) | 2013-11-18 | 2016-10-06 | Massachusetts Institute Of Technology | Compositions and methods for treating immune and viral disorders and modulating protein-rna interaction |
| KR102622656B1 (ko) | 2016-02-18 | 2024-01-10 | 인버사, 인크. | 5'-아데노신 디포스페이트 리보오스 (adpr)의 사용 방법 |
| US10946034B2 (en) | 2018-03-27 | 2021-03-16 | Invirsa, Inc. | Methods for the use of 5′-adenosine diphosphate ribose (ADPR) |
-
2019
- 2019-03-26 US US16/364,760 patent/US10946034B2/en active Active
- 2019-03-26 EP EP23168073.7A patent/EP4226971A1/en active Pending
- 2019-03-26 JP JP2020551992A patent/JP7242696B2/ja active Active
- 2019-03-26 ES ES19726521T patent/ES2949441T3/es active Active
- 2019-03-26 EP EP19726521.8A patent/EP3773604B1/en active Active
- 2019-03-26 WO PCT/US2019/023977 patent/WO2019191026A2/en not_active Ceased
-
2021
- 2021-02-09 US US17/171,548 patent/US11793826B2/en active Active
-
2023
- 2023-03-08 JP JP2023035224A patent/JP7745584B2/ja active Active
- 2023-09-11 US US18/244,693 patent/US12233083B2/en active Active
-
2025
- 2025-01-17 US US19/029,481 patent/US20250161343A1/en not_active Abandoned
- 2025-05-02 JP JP2025076718A patent/JP2025118771A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021519315A5 (enExample) | ||
| ES2553788T3 (es) | 3,5-diamino-6-cloro-N-(N-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil) carbamimidoil)pirazino-2-carboxamida | |
| JP2023071933A5 (enExample) | ||
| US5789391A (en) | Method of treating sinusitis with uridine triphosphates and related compounds | |
| JP6392241B2 (ja) | ３，５−ジアミノ−６−クロロ−ｎ−（ｎ−（４−フェニルブチル）カルバムイミドイル）ピラジン−２−カルボキサミド化合物 | |
| EP0889728B1 (en) | Method of treating ciliary dyskinesia with uridine triphosphates and related compounds | |
| JP6021117B2 (ja) | エアロゾルのピルフェニドンおよびピリドンアナログの化合物、および、その使用 | |
| CN105073717B (zh) | 可用于治疗由黏膜水化不足造成的疾病的氯-吡嗪甲酰胺衍生物 | |
| JP2014518268A5 (enExample) | ||
| JP2018505192A5 (enExample) | ||
| ES2949441T3 (es) | Métodos para el uso de 5'-adenosina difosfato ribosa (ADPR) | |
| BR112017005104B1 (pt) | Derivados de 5,6-di-hidro-4h-benzotieno-[2,3-d]azepina, seus usos, composição farmacêutica e processo para a preparação dos mesmos | |
| BR112013032771B1 (pt) | dipeptídio quimicamente e metabolicamente estável possuindo potente atividade bloqueadora de canais de sódio | |
| US20110054163A1 (en) | P2y6 receptor agonists for treating lung diseases | |
| JP2019505596A5 (enExample) | ||
| CN104955812B (zh) | 经芳烷基和芳氧基烷基取代的上皮钠通道阻断化合物 | |
| HRP20211942T1 (hr) | Medicinska uporaba 5'-adenozin difosfat riboze (adpr) | |
| BR112018074532B1 (pt) | Composição farmacêutica, aerossol, e, kit. | |
| US20110166149A1 (en) | Pteridine derivatives for treating respiratory disease | |
| CN104507918A (zh) | 用于治疗或预防肺炎病毒感染和相关疾病的组合物和方法 | |
| US20030036527A1 (en) | Method of treating ciliary dyskinesia with dinucleoside polyphosphate compounds | |
| ES2239728T3 (es) | Combinaciones farmaceuticas de agonistas del receptor de adenosina a-2a y del receptor adrenergico beta-2. | |
| JP2023524064A5 (enExample) | ||
| WO2021253647A1 (zh) | 小分子抑制剂在治疗呼吸道病毒性肺炎上的应用 | |
| EP1941883A1 (en) | Use of sodium blockers for an early therapy of obstructive lung diseases |