ES2949441T3 - Métodos para el uso de 5'-adenosina difosfato ribosa (ADPR) - Google Patents
Métodos para el uso de 5'-adenosina difosfato ribosa (ADPR) Download PDFInfo
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- ES2949441T3 ES2949441T3 ES19726521T ES19726521T ES2949441T3 ES 2949441 T3 ES2949441 T3 ES 2949441T3 ES 19726521 T ES19726521 T ES 19726521T ES 19726521 T ES19726521 T ES 19726521T ES 2949441 T3 ES2949441 T3 ES 2949441T3
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- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
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Landscapes
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- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201862648585P | 2018-03-27 | 2018-03-27 | |
| US201862693021P | 2018-07-02 | 2018-07-02 | |
| PCT/US2019/023977 WO2019191026A2 (en) | 2018-03-27 | 2019-03-26 | Methods for the use of 5'-adenosine diphosphate ribose (adpr) |
Publications (1)
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| ES2949441T3 true ES2949441T3 (es) | 2023-09-28 |
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| JP (3) | JP7242696B2 (enExample) |
| ES (1) | ES2949441T3 (enExample) |
| WO (1) | WO2019191026A2 (enExample) |
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| KR102883682B1 (ko) | 2016-02-18 | 2025-11-10 | 인버사, 인크. | 5'-아데노신 디포스페이트 리보오스 (adpr)의 사용 방법 |
| US10946034B2 (en) | 2018-03-27 | 2021-03-16 | Invirsa, Inc. | Methods for the use of 5′-adenosine diphosphate ribose (ADPR) |
| CN111714619B (zh) * | 2020-07-15 | 2023-03-14 | 上海市浦东新区人民医院 | 成纤维生长因子6在制备缓解非酒精性脂肪性肝炎肝损伤的药物中的应用 |
| CN112972453B (zh) * | 2021-03-05 | 2022-04-15 | 中国人民解放军军事科学院军事医学研究院 | MDL-800在制备抑制SARS-CoV-2病毒易感性药物中的应用 |
| KR102789553B1 (ko) * | 2021-09-07 | 2025-04-03 | 주식회사 펄스인마이어스 | 방사선 및/또는 항암 치료 보조 요법으로 아데노신 디포스페이트 리보오스의 활용 |
| WO2025122455A1 (en) * | 2023-12-04 | 2025-06-12 | Invirsa, Inc. | Methods for the use of 5'-adenosine diphosphate ribose (adpr) for vegf modulation |
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| JPH04273826A (ja) * | 1991-02-27 | 1992-09-30 | Dainippon Ink & Chem Inc | 抗ｒｓウイルス剤 |
| EP0618214A1 (en) | 1993-04-01 | 1994-10-05 | Merrell Dow Pharmaceuticals Inc. | Unsaturated phosphonate derivatives of purines and pyrimidines |
| JPH07247210A (ja) | 1994-03-09 | 1995-09-26 | Sunstar Inc | 口腔用組成物 |
| US6339073B1 (en) | 1997-09-11 | 2002-01-15 | Oxigene, Inc. | Uses of nicotinamide adenine dinucleotide and its derivatives for treatment of malignant and infectious diseases |
| BR0008498A (pt) | 1999-02-26 | 2002-02-05 | Inspire Pharmaceuticals Inc | Método de promoção de hidratação de mucosas com certos difosfatos de uridina, adenina e citidina e seus análogos |
| EP1192258A2 (en) | 1999-06-16 | 2002-04-03 | Icos Corporation | Human poly(adp-ribose) polymerase 2 materials and methods |
| US6528042B1 (en) | 1999-10-08 | 2003-03-04 | Galileo Laboratories, Inc. | Compositions of flavonoids for use as cytoprotectants and methods of making and using them |
| US7115585B2 (en) | 2000-08-21 | 2006-10-03 | Inspire Pharmaceuticals, Inc. | Compositions for treating epithelial and retinal tissue diseases |
| WO2003011885A1 (en) | 2001-07-25 | 2003-02-13 | Celltech R & D Limited | Non-natural carbon-linked nucleotides and dinucleotides |
| ATE417616T1 (de) | 2002-05-21 | 2009-01-15 | Abbott Lab | Behandlung von mukositis |
| JP2005089450A (ja) | 2003-08-11 | 2005-04-07 | Fujisawa Pharmaceut Co Ltd | Ｒｓウィルスによる感染症の予防または治療剤 |
| US20070212395A1 (en) | 2006-03-08 | 2007-09-13 | Allergan, Inc. | Ocular therapy using sirtuin-activating agents |
| US20050276762A1 (en) | 2004-06-15 | 2005-12-15 | Tapas Das | Topical compositions containing 5'-adenosine-diphosphate ribose |
| WO2006127987A2 (en) | 2005-05-25 | 2006-11-30 | Sirtris Pharmaceuticals, Inc. | Treatment of eye disorders with sirtuin modulators |
| ATE540689T1 (de) | 2005-11-14 | 2012-01-15 | Centre Nat Rech Scient | Macroh2a non-histone domäne als hemmer der parp-1-aktivität und verwendung davon |
| WO2008154129A1 (en) | 2007-06-08 | 2008-12-18 | Bausch & Lomb Incorporated | Pharmaceutical compositions and method for treating, reducing, ameliorating, alleviating, or preventing dry eye |
| US20110217262A1 (en) | 2010-03-05 | 2011-09-08 | Kornfield Julia A | Treatment of Ocular Surface Disorders by Increasing Conjunctival Vascular Permeability |
| WO2011141909A2 (en) | 2010-05-10 | 2011-11-17 | Radikal Therapeutics Inc. | Lipoic acid and nitroxide derivatives and uses thereof |
| KR101967938B1 (ko) | 2011-05-12 | 2019-04-10 | 포어사이트 바이오쎄라퓨틱스, 인코퍼레이티드 | 스테로이드 또는 비-스테로이드성 소염제를 갖는 안정한 포비돈-요오드 조성물 |
| WO2015073319A1 (en) * | 2013-11-18 | 2015-05-21 | Massachusetts Institute Of Technology | Compositions and methods for treating immune and viral disorders and modulating protein-rna interaction |
| KR102883682B1 (ko) | 2016-02-18 | 2025-11-10 | 인버사, 인크. | 5'-아데노신 디포스페이트 리보오스 (adpr)의 사용 방법 |
| US10946034B2 (en) | 2018-03-27 | 2021-03-16 | Invirsa, Inc. | Methods for the use of 5′-adenosine diphosphate ribose (ADPR) |
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| US20190298752A1 (en) | 2019-10-03 |
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| US20230414647A1 (en) | 2023-12-28 |
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| EP4226971A1 (en) | 2023-08-16 |
| JP7745584B2 (ja) | 2025-09-29 |
| JP2023071933A (ja) | 2023-05-23 |
| WO2019191026A3 (en) | 2019-12-05 |
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