JP2021518111A5 - - Google Patents

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Publication number
JP2021518111A5
JP2021518111A5 JP2020549002A JP2020549002A JP2021518111A5 JP 2021518111 A5 JP2021518111 A5 JP 2021518111A5 JP 2020549002 A JP2020549002 A JP 2020549002A JP 2020549002 A JP2020549002 A JP 2020549002A JP 2021518111 A5 JP2021518111 A5 JP 2021518111A5
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JP
Japan
Prior art keywords
cells
nucleic acid
cell
amino acid
cancer
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Granted
Application number
JP2020549002A
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English (en)
Japanese (ja)
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JP2021518111A (ja
JP7314161B2 (ja
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Priority claimed from PCT/US2019/021833 external-priority patent/WO2019178085A1/en
Publication of JP2021518111A publication Critical patent/JP2021518111A/ja
Publication of JP2021518111A5 publication Critical patent/JP2021518111A5/ja
Priority to JP2023114641A priority Critical patent/JP7696958B2/ja
Application granted granted Critical
Publication of JP7314161B2 publication Critical patent/JP7314161B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020549002A 2018-03-14 2019-03-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法 Active JP7314161B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023114641A JP7696958B2 (ja) 2018-03-14 2023-07-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862643139P 2018-03-14 2018-03-14
US62/643,139 2018-03-14
PCT/US2019/021833 WO2019178085A1 (en) 2018-03-14 2019-03-12 Il-13 receptor alpha 2 targeted, zetakine directed t cell immunotherapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023114641A Division JP7696958B2 (ja) 2018-03-14 2023-07-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法

Publications (3)

Publication Number Publication Date
JP2021518111A JP2021518111A (ja) 2021-08-02
JP2021518111A5 true JP2021518111A5 (enExample) 2022-03-18
JP7314161B2 JP7314161B2 (ja) 2023-07-25

Family

ID=67907266

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020549002A Active JP7314161B2 (ja) 2018-03-14 2019-03-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法
JP2023114641A Active JP7696958B2 (ja) 2018-03-14 2023-07-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023114641A Active JP7696958B2 (ja) 2018-03-14 2023-07-12 ゼータカインにより指向性を付与したIL-13受容体α2標的T細胞免疫療法

Country Status (13)

Country Link
US (1) US12606603B2 (enExample)
EP (2) EP4491718A3 (enExample)
JP (2) JP7314161B2 (enExample)
KR (2) KR20260021083A (enExample)
CN (1) CN112088165A (enExample)
AU (2) AU2019234580B2 (enExample)
BR (1) BR112020018534A2 (enExample)
CA (1) CA3093791A1 (enExample)
EA (1) EA202091984A1 (enExample)
IL (1) IL277268A (enExample)
MX (2) MX2020009464A (enExample)
SG (1) SG11202008926RA (enExample)
WO (1) WO2019178085A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112020018670A2 (pt) 2018-03-14 2021-01-05 Seattle Children's Hospital (dba Seattle Children's Research Institute) Receptor de antígeno quimérico de receptor alfa 2 da il-13 (il13ra2) para imunoterapia com células t específicas para tumor
WO2024041650A1 (en) * 2022-08-25 2024-02-29 Nanjing Legend Biotech Co., Ltd. Chimeric antigen receptors targeting interleukin 13 receptor subunit alpha 2 and methods of use thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090257994A1 (en) * 2001-04-30 2009-10-15 City Of Hope Chimeric immunoreceptor useful in treating human cancers
US20090098142A1 (en) * 2004-06-09 2009-04-16 Kasaian Marion T Methods and compositions for treating and monitoring treatment of IL-13-associated disorders
SG186017A1 (en) 2007-11-30 2012-12-28 Kalobios Pharmaceuticals Inc Antibodies to the pcrv antigen of pseudomonas aeruginosa
US8822647B2 (en) 2008-08-26 2014-09-02 City Of Hope Method and compositions using a chimeric antigen receptor for enhanced anti-tumor effector functioning of T cells
ES2717629T3 (es) * 2009-11-03 2019-06-24 Hope City Receptor del factor de crecimiento epidérmico truncado (EGFRt) para selección de células T transducidas
EP3594245A1 (en) 2012-02-13 2020-01-15 Seattle Children's Hospital d/b/a Seattle Children's Research Institute Bispecific chimeric antigen receptors and therapeutic uses thereof
PL3824905T3 (pl) 2012-08-20 2025-05-05 Fred Hutchinson Cancer Center Sposób i kompozycje do immunoterapii komórkowej
HK1214161A1 (zh) 2012-11-07 2016-07-22 辉瑞公司 抗IL-13受体α2抗体和抗体-药物缀合物
CA2893359C (en) 2012-12-05 2021-12-28 Strategia Therapeutics, Inc. Protein expression enhancing polypeptides
TWI654206B (zh) 2013-03-16 2019-03-21 諾華公司 使用人類化抗-cd19嵌合抗原受體治療癌症
EP3974520A1 (en) * 2013-05-14 2022-03-30 Board of Regents, The University of Texas System Human application of engineered chimeric antigen receptor (car) t-cells
TWI805109B (zh) 2014-08-28 2023-06-11 美商奇諾治療有限公司 對cd19具專一性之抗體及嵌合抗原受體
EP3587446A1 (en) * 2014-09-19 2020-01-01 City of Hope Costimulatory chimeric antigen receptor t cells targeting il13 r alpha 2
JP7264592B2 (ja) 2015-01-26 2023-04-25 ザ ユニバーシティー オブ シカゴ IL13Rα2結合剤及び癌治療におけるその使用
AU2016297605A1 (en) 2015-07-21 2018-02-15 City Of Hope T cells for expression of chimeric antigen receptors and other receptors
CN116334205A (zh) * 2015-09-03 2023-06-27 诺华股份有限公司 预测细胞因子释放综合征的生物标志物
BR112018015836A2 (en) * 2016-02-05 2018-12-26 City Of Hope engineered t-cell administration for central nervous system cancer treatment
WO2017172981A2 (en) 2016-03-29 2017-10-05 University Of Southern California Chimeric antigen receptors targeting cancer
KR20190015520A (ko) 2016-06-07 2019-02-13 마크로제닉스, 인크. 조합 치료법
CA3031955A1 (en) 2016-07-29 2018-02-01 Juno Therapeutics, Inc. Immunomodulatory polypeptides and related compositions and methods
JP2019530440A (ja) * 2016-09-02 2019-10-24 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア インターロイキン6受容体α結合単鎖可変断片を含む方法および組成物
US12083148B2 (en) 2017-02-22 2024-09-10 H. Lee Moffitt Cancer Center And Research Institute, Inc. IL13Ra2-binding chimeric antigen receptors
BR112020018670A2 (pt) 2018-03-14 2021-01-05 Seattle Children's Hospital (dba Seattle Children's Research Institute) Receptor de antígeno quimérico de receptor alfa 2 da il-13 (il13ra2) para imunoterapia com células t específicas para tumor

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