JP2021516254A5 - - Google Patents
Info
- Publication number
- JP2021516254A5 JP2021516254A5 JP2020560859A JP2020560859A JP2021516254A5 JP 2021516254 A5 JP2021516254 A5 JP 2021516254A5 JP 2020560859 A JP2020560859 A JP 2020560859A JP 2020560859 A JP2020560859 A JP 2020560859A JP 2021516254 A5 JP2021516254 A5 JP 2021516254A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- antibody according
- sialyl
- stn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT110526A PT110526B (pt) | 2018-01-26 | 2018-01-26 | Anticorpo, fragmento funcional ou sonda do mesmo contra antigénios tumorais |
| PT110526 | 2018-01-26 | ||
| PCT/PT2019/000001 WO2019147152A1 (en) | 2018-01-26 | 2019-01-17 | L2a5 antibody or functional fragment thereof against tumour antigens |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021516254A JP2021516254A (ja) | 2021-07-01 |
| JP2021516254A5 true JP2021516254A5 (https=) | 2022-02-24 |
| JP7324777B2 JP7324777B2 (ja) | 2023-08-10 |
Family
ID=65244573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020560859A Active JP7324777B2 (ja) | 2018-01-26 | 2019-01-17 | 腫瘍抗原に対するｌ２ａ５抗体またはその機能的断片 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11353460B2 (https=) |
| EP (1) | EP3743726B1 (https=) |
| JP (1) | JP7324777B2 (https=) |
| CN (1) | CN113287018B (https=) |
| AU (1) | AU2019211035B2 (https=) |
| BR (1) | BR112020014931A2 (https=) |
| CA (1) | CA3089300A1 (https=) |
| EA (1) | EA202091760A1 (https=) |
| IL (1) | IL276208B1 (https=) |
| MX (1) | MX2020007828A (https=) |
| PT (1) | PT110526B (https=) |
| SG (1) | SG11202006897VA (https=) |
| WO (1) | WO2019147152A1 (https=) |
| ZA (1) | ZA202005023B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022195797A1 (ja) * | 2021-03-18 | 2022-09-22 | 国立大学法人弘前大学 | 末端シアル酸残基がα２，６結合でガラクトースに結合した糖鎖に特異的に結合するモノクローナル抗体、及び、末端シアル酸残基がα２，６結合でガラクトースに結合した糖鎖の測定方法 |
| WO2022224242A1 (en) * | 2021-04-20 | 2022-10-27 | Ramot At Tel-Aviv University Ltd. | Humanized anti-sialyl-tn glycan antibodies and uses thereof |
| GB2619976A (en) * | 2022-06-24 | 2023-12-27 | Cellmabs S A | Humanised antibodies or functional fragments thereof against tumour antigens |
| CN121219019A (zh) | 2023-05-05 | 2025-12-26 | 百欧恩泰欧洲股份公司 | 用于增强靶向癌症相关抗原的采用新型连接子-有效载荷系统的抗体药物偶联物 |
| WO2026057354A1 (en) * | 2024-09-10 | 2026-03-19 | Invox Pharma Limited | Anti-sialyl-tn antigen-binding proteins |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0216846B2 (en) | 1985-04-01 | 1995-04-26 | Celltech Limited | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| DE68922806T2 (de) * | 1988-03-11 | 1996-02-29 | Biomembrane Inst | Monoklonale antikörper und herstellung eines impfstoffes gegen menschliche krebsantigene durch immunisierung mit menschlichem und tierischem mucin und mit synthetischen gluciden-trägerkonjugaten. |
| WO1995029927A2 (en) | 1994-05-02 | 1995-11-09 | Biomira, Inc. | Process for preparation of glycosides of tumor-associated carbohydrate antigens |
| WO1998046246A1 (en) | 1997-04-16 | 1998-10-22 | Sloan-Kettering Institute For Cancer Research | α-O-LINKED GLYCOCONJUGATES WITH CLUSTERED (2,6)-ST EPITOPES, METHODS OF PREPARATION AND USES THEREOF |
| CU22731A1 (es) * | 1998-02-05 | 2002-02-28 | Centro Inmunologia Molecular | Anticuerpo monoclonal que reconoce el oligosacárido ácido siálico n´glicolilado-galactosa-glucosa (ngcneu-gal-glu) en tumores malignos y composiciones farmacéuticas que los contienen |
| JP3809277B2 (ja) | 1998-03-05 | 2006-08-16 | 生化学工業株式会社 | Ｎ−アセチルグルコサミン−６−ｏ−硫酸基転移酵素のポリペプチド及びそれをコードするｄｎａ |
| GB9917012D0 (en) | 1999-07-20 | 1999-09-22 | Pharmacia & Upjohn Spa | Combined preparations comprising antitumor agents |
| EP2261255A1 (en) | 2003-07-15 | 2010-12-15 | The Regents of The University of California | Methods for purifying sialic acid-specific antibodies and composition comprising affinity-purified antibodies |
| US8148335B2 (en) * | 2004-06-23 | 2012-04-03 | Children's Hospital & Research Center Oakland | De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy |
| AU2007304590A1 (en) | 2006-10-04 | 2008-04-10 | Cancer Research Technology Limited | Generation of a cancer-specific immune response toward MUC1 and cancer specific MUC1 antibodies |
| JP5156887B2 (ja) * | 2007-02-14 | 2013-03-06 | 独立行政法人科学技術振興機構 | ２−６シアリル６−スルホ糖鎖に対する抗体 |
| EP2014302A1 (en) | 2007-07-12 | 2009-01-14 | Institut Curie | An antibody specific for the Tn antigen for the treatment of cancer |
| FI20070853A0 (fi) * | 2007-11-09 | 2007-11-09 | Glykos Finland Oy | Glykaania sitovat monoklonaaliset vasta-aineet |
| EP2287202A1 (en) | 2009-08-07 | 2011-02-23 | Dublin City University | Anti-sialic acid antibody molecules |
| EP2524233A4 (en) | 2010-01-15 | 2013-07-31 | Univ California | COMPOSITIONS AND METHOD FOR DETECTING CANCER |
| US9796785B2 (en) | 2013-05-02 | 2017-10-24 | National Institute Of Advanced Industrial Science And Technology | Monoclonal antibody recognizing sialylated sugar chains |
| WO2014191128A1 (en) | 2013-05-29 | 2014-12-04 | Cellectis | Methods for engineering t cells for immunotherapy by using rna-guided cas nuclease system |
| AU2014332442B2 (en) | 2013-08-26 | 2019-12-19 | Biontech Research And Development, Inc. | Nucleic acids encoding human antibodies to Sialyl-Lewis |
| EP2990416B1 (en) | 2014-08-29 | 2018-06-20 | GEMoaB Monoclonals GmbH | Universal chimeric antigen receptor expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders |
| WO2016057916A1 (en) * | 2014-10-10 | 2016-04-14 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
| WO2017040529A1 (en) * | 2015-08-31 | 2017-03-09 | Bluebird Bio, Inc. | Anti-sialyl tn chimeric antigen receptors |
| WO2018217116A1 (en) * | 2017-05-25 | 2018-11-29 | Instituto De Patologia E Imunologia Da Universidade Do Porto (Ipatimup) | Detection and isolation of cancer cells from body fluids based on a glycosylation pattern and methods of use thereof |
-
2018
- 2018-01-26 PT PT110526A patent/PT110526B/pt active IP Right Grant
-
2019
- 2019-01-17 EA EA202091760A patent/EA202091760A1/ru unknown
- 2019-01-17 IL IL276208A patent/IL276208B1/en unknown
- 2019-01-17 BR BR112020014931-4A patent/BR112020014931A2/pt unknown
- 2019-01-17 CN CN201980022395.6A patent/CN113287018B/zh active Active
- 2019-01-17 US US16/964,900 patent/US11353460B2/en active Active
- 2019-01-17 MX MX2020007828A patent/MX2020007828A/es unknown
- 2019-01-17 EP EP19702492.0A patent/EP3743726B1/en active Active
- 2019-01-17 SG SG11202006897VA patent/SG11202006897VA/en unknown
- 2019-01-17 CA CA3089300A patent/CA3089300A1/en active Pending
- 2019-01-17 JP JP2020560859A patent/JP7324777B2/ja active Active
- 2019-01-17 AU AU2019211035A patent/AU2019211035B2/en active Active
- 2019-01-17 WO PCT/PT2019/000001 patent/WO2019147152A1/en not_active Ceased
-
2020
- 2020-08-13 ZA ZA2020/05023A patent/ZA202005023B/en unknown
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