JP2021514011A5 - - Google Patents

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Publication number
JP2021514011A5
JP2021514011A5 JP2020566549A JP2020566549A JP2021514011A5 JP 2021514011 A5 JP2021514011 A5 JP 2021514011A5 JP 2020566549 A JP2020566549 A JP 2020566549A JP 2020566549 A JP2020566549 A JP 2020566549A JP 2021514011 A5 JP2021514011 A5 JP 2021514011A5
Authority
JP
Japan
Prior art keywords
optionally substituted
membered
heteroaryl
heteroatoms selected
heterocyclyl
Prior art date
Application number
JP2020566549A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021514011A (ja
JPWO2019164949A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/018774 external-priority patent/WO2019164949A1/en
Publication of JP2021514011A publication Critical patent/JP2021514011A/ja
Publication of JPWO2019164949A5 publication Critical patent/JPWO2019164949A5/ja
Publication of JP2021514011A5 publication Critical patent/JP2021514011A5/ja
Pending legal-status Critical Current

Links

JP2020566549A 2018-02-20 2019-02-20 Ｅｇｆｒ阻害剤の組合せ医薬製剤およびその使用法 Pending JP2021514011A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862632806P 2018-02-20 2018-02-20
US62/632,806 2018-02-20
US201862744083P 2018-10-10 2018-10-10
US62/744,083 2018-10-10
PCT/US2019/018774 WO2019164949A1 (en) 2018-02-20 2019-02-20 Pharmaceutical combinations of egfr inhibitors and methods of use thereof

Publications (3)

Publication Number Publication Date
JP2021514011A JP2021514011A (ja) 2021-06-03
JPWO2019164949A5 JPWO2019164949A5 (https=) 2022-02-25
JP2021514011A5 true JP2021514011A5 (https=) 2022-02-25

Family

ID=67688573

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020566549A Pending JP2021514011A (ja) 2018-02-20 2019-02-20 Ｅｇｆｒ阻害剤の組合せ医薬製剤およびその使用法

Country Status (6)

Country Link
US (1) US20210085688A1 (https=)
EP (1) EP3755337A4 (https=)
JP (1) JP2021514011A (https=)
AU (1) AU2019225807A1 (https=)
CA (1) CA3087797A1 (https=)
WO (1) WO2019164949A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021514011A (ja) * 2018-02-20 2021-06-03 デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド Ｅｇｆｒ阻害剤の組合せ医薬製剤およびその使用法
EP3755689B1 (en) 2018-02-20 2023-12-06 Dana-Farber Cancer Institute, Inc. Inhibitors of egfr and methods of use thereof
AU2019225799A1 (en) * 2018-02-20 2020-07-09 Dana-Farber Cancer Institute, Inc. Pharmaceutical combinations of EGFR inhibitors and methods of use thereof
CN114553638A (zh) 2018-09-15 2022-05-27 华为技术有限公司 一种通信方法、设备和系统
AU2022230397A1 (en) * 2021-03-02 2023-09-21 Dana-Farber Cancer Institute, Inc. Covalent egfr inhibitors and methods of use thereof
US20250197390A1 (en) * 2022-03-16 2025-06-19 Jiangsu Hengrui Pharmaceuticals Co., Ltd. Fused heterocyclic compound, and preparation method therefor and medical use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070105835A1 (en) * 2005-11-07 2007-05-10 Kazantsev Aleksey G Compositions and methods for modulating poly(ADP-ribose) polymerase activity
CA2746220A1 (en) * 2008-12-08 2010-07-08 Vm Pharma Llc Compositions of protein receptor tyrosine kinase inhibitors
CN103702990B (zh) * 2011-07-27 2015-09-09 阿斯利康(瑞典)有限公司 2-(2,4,5-取代苯胺)嘧啶衍生物作为egfr调谐子用于治疗癌症
WO2014160430A1 (en) * 2013-03-13 2014-10-02 Georgetown University Small molecule lrrk2 and erk5 inhibitors
US20170114323A1 (en) * 2014-06-19 2017-04-27 Whitehead Institute For Biomedical Research Uses of kinase inhibitors for inducing and maintaining pluripotency
EP3399968B8 (en) * 2016-01-07 2021-12-01 Xuanzhu Biopharmaceutical Co., Ltd. Selective inhibitors of clinically important mutants of the egfr tyrosine kinase
US11155556B2 (en) * 2016-04-07 2021-10-26 Dana-Farber Cancer Institute, Inc. Pyrimido-diazepinone kinase scaffold compounds and methods for treating PI3K-mediated disorders
JP2021514011A (ja) * 2018-02-20 2021-06-03 デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド Ｅｇｆｒ阻害剤の組合せ医薬製剤およびその使用法
AU2019225811A1 (en) * 2018-02-20 2020-07-09 Dana-Farber Cancer Institute, Inc. Degraders of EGFR and methods of use thereof
EP3755689B1 (en) * 2018-02-20 2023-12-06 Dana-Farber Cancer Institute, Inc. Inhibitors of egfr and methods of use thereof
US20200377477A1 (en) * 2018-02-20 2020-12-03 Dana-Farber Cancer Institute, Inc. Degraders of egfr and methods of use thereof

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