JP2021514398A5 - - Google Patents
Info
- Publication number
- JP2021514398A5 JP2021514398A5 JP2020566546A JP2020566546A JP2021514398A5 JP 2021514398 A5 JP2021514398 A5 JP 2021514398A5 JP 2020566546 A JP2020566546 A JP 2020566546A JP 2020566546 A JP2020566546 A JP 2020566546A JP 2021514398 A5 JP2021514398 A5 JP 2021514398A5
- Authority
- JP
- Japan
- Prior art keywords
- carbon atoms
- group
- combination pharmaceutical
- egfr inhibitor
- pharmaceutical preparation
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862632798P | 2018-02-20 | 2018-02-20 | |
| US62/632,798 | 2018-02-20 | ||
| PCT/US2019/018770 WO2019164945A1 (en) | 2018-02-20 | 2019-02-20 | Pharmaceutical combinations of egfr inhibitors and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021514398A JP2021514398A (ja) | 2021-06-10 |
| JP2021514398A5 true JP2021514398A5 (https=) | 2022-02-25 |
| JPWO2019164945A5 JPWO2019164945A5 (https=) | 2022-02-25 |
Family
ID=67686991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020566546A Pending JP2021514398A (ja) | 2018-02-20 | 2019-02-20 | Ｅｇｆｒ阻害剤の組合せ医薬製剤およびその使用法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20210077469A1 (https=) |
| EP (1) | EP3755330A4 (https=) |
| JP (1) | JP2021514398A (https=) |
| AU (1) | AU2019225803A1 (https=) |
| CA (1) | CA3088972A1 (https=) |
| WO (1) | WO2019164945A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12377080B2 (en) | 2019-06-21 | 2025-08-05 | Dana-Farber Cancer Institute, Inc. | Allosteric EGFR inhibitors and methods of use thereof |
| JP7561777B2 (ja) * | 2019-06-21 | 2024-10-04 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | 新規ｅｇｆｒ阻害剤 |
| IL326879A (en) | 2019-11-11 | 2026-04-01 | Dana Farber Cancer Inst Inc | EGFR allosteric inhibitors and methods of using them |
| CN111592535B (zh) * | 2020-06-22 | 2021-07-20 | 通化师范学院 | 一种抗egfr突变的抑制剂eai045的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2049518B1 (en) * | 2006-05-31 | 2011-08-31 | Takeda San Diego, Inc. | Indazole and isoindole derivatives as glucokinase activating agents. |
| WO2012129562A2 (en) * | 2011-03-24 | 2012-09-27 | The Scripps Research Institute | Compounds and methods for inducing chondrogenesis |
| CN103702990B (zh) * | 2011-07-27 | 2015-09-09 | 阿斯利康(瑞典)有限公司 | 2-(2,4,5-取代苯胺)嘧啶衍生物作为egfr调谐子用于治疗癌症 |
| CN105315259B (zh) * | 2014-07-29 | 2018-03-09 | 上海艾力斯医药科技有限公司 | 吡啶胺基嘧啶衍生物、其制备方法及应用 |
| CA2987914C (en) * | 2015-06-30 | 2022-09-13 | Dana-Farber Cancer Institute, Inc. | Inhibitors of egfr and methods of use thereof |
| EP3445357B1 (en) * | 2016-04-22 | 2021-05-26 | Dana-Farber Cancer Institute, Inc. | Bifunctional molecules for degradation of egfr and methods of use |
-
2019
- 2019-02-20 US US16/971,021 patent/US20210077469A1/en not_active Abandoned
- 2019-02-20 EP EP19758033.5A patent/EP3755330A4/en not_active Withdrawn
- 2019-02-20 CA CA3088972A patent/CA3088972A1/en active Pending
- 2019-02-20 WO PCT/US2019/018770 patent/WO2019164945A1/en not_active Ceased
- 2019-02-20 AU AU2019225803A patent/AU2019225803A1/en not_active Abandoned
- 2019-02-20 JP JP2020566546A patent/JP2021514398A/ja active Pending
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