JP2021514399A5 - - Google Patents
Info
- Publication number
- JP2021514399A5 JP2021514399A5 JP2020566547A JP2020566547A JP2021514399A5 JP 2021514399 A5 JP2021514399 A5 JP 2021514399A5 JP 2020566547 A JP2020566547 A JP 2020566547A JP 2020566547 A JP2020566547 A JP 2020566547A JP 2021514399 A5 JP2021514399 A5 JP 2021514399A5
- Authority
- JP
- Japan
- Prior art keywords
- carbon atoms
- phenyl
- heteroaryl
- membered
- compound according
- Prior art date
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862632817P | 2018-02-20 | 2018-02-20 | |
| US62/632,817 | 2018-02-20 | ||
| US201862744085P | 2018-10-10 | 2018-10-10 | |
| US62/744,085 | 2018-10-10 | ||
| PCT/US2019/018772 WO2019164947A1 (en) | 2018-02-20 | 2019-02-20 | Inhibitors of egfr and methods of use thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021514399A JP2021514399A (ja) | 2021-06-10 |
| JPWO2019164947A5 JPWO2019164947A5 (https=) | 2022-02-25 |
| JP2021514399A5 true JP2021514399A5 (https=) | 2022-02-25 |
| JP7335275B2 JP7335275B2 (ja) | 2023-08-29 |
Family
ID=67687389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020566547A Active JP7335275B2 (ja) | 2018-02-20 | 2019-02-20 | Ｅｇｆｒの阻害剤およびその使用法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11584746B2 (https=) |
| EP (1) | EP3755689B1 (https=) |
| JP (1) | JP7335275B2 (https=) |
| AU (1) | AU2019225805A1 (https=) |
| CA (1) | CA3087716A1 (https=) |
| WO (1) | WO2019164947A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021514011A (ja) * | 2018-02-20 | 2021-06-03 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | Ｅｇｆｒ阻害剤の組合せ医薬製剤およびその使用法 |
| CA3087288A1 (en) * | 2018-02-20 | 2019-08-29 | Dana-Farber Cancer Institute, Inc. | Inhibitors of egfr and methods of use thereof |
| AU2019225799A1 (en) * | 2018-02-20 | 2020-07-09 | Dana-Farber Cancer Institute, Inc. | Pharmaceutical combinations of EGFR inhibitors and methods of use thereof |
| WO2024168152A1 (en) * | 2023-02-08 | 2024-08-15 | The Research Foundation For The State University Of New York | Benzodiazepinone-derived inhibitors of egfr and her2 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070105835A1 (en) | 2005-11-07 | 2007-05-10 | Kazantsev Aleksey G | Compositions and methods for modulating poly(ADP-ribose) polymerase activity |
| US20110028458A1 (en) * | 2008-04-11 | 2011-02-03 | Thallion Pharmaceuticals Inc. | Inhibition of cell migration by a farnesylated dibenzodiazepinone |
| CA2746220A1 (en) | 2008-12-08 | 2010-07-08 | Vm Pharma Llc | Compositions of protein receptor tyrosine kinase inhibitors |
| EP2379559B1 (en) | 2009-01-06 | 2017-10-25 | Dana-Farber Cancer Institute, Inc. | Pyrimido-diazepinone kinase scaffold compounds and methods of treating disorders |
| US9156233B2 (en) | 2012-10-22 | 2015-10-13 | Us Floors, Inc. | Engineered waterproof flooring and wall covering planks |
| WO2014160430A1 (en) | 2013-03-13 | 2014-10-02 | Georgetown University | Small molecule lrrk2 and erk5 inhibitors |
| US20170114323A1 (en) | 2014-06-19 | 2017-04-27 | Whitehead Institute For Biomedical Research | Uses of kinase inhibitors for inducing and maintaining pluripotency |
| US10702527B2 (en) | 2015-06-12 | 2020-07-07 | Dana-Farber Cancer Institute, Inc. | Combination therapy of transcription inhibitors and kinase inhibitors |
| US11155556B2 (en) | 2016-04-07 | 2021-10-26 | Dana-Farber Cancer Institute, Inc. | Pyrimido-diazepinone kinase scaffold compounds and methods for treating PI3K-mediated disorders |
| TW201834651A (zh) | 2016-12-22 | 2018-10-01 | 瑞士商赫孚孟拉羅股份公司 | 化合物 |
| WO2018220149A1 (en) | 2017-06-02 | 2018-12-06 | F. Hoffmann-La Roche Ag | Compounds |
| CA3087288A1 (en) | 2018-02-20 | 2019-08-29 | Dana-Farber Cancer Institute, Inc. | Inhibitors of egfr and methods of use thereof |
| JP2021514011A (ja) | 2018-02-20 | 2021-06-03 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | Ｅｇｆｒ阻害剤の組合せ医薬製剤およびその使用法 |
| KR102277626B1 (ko) | 2018-08-16 | 2021-07-15 | 한국화학연구원 | 이소인돌린-1온 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 |
-
2019
- 2019-02-20 EP EP19757550.9A patent/EP3755689B1/en active Active
- 2019-02-20 US US16/970,931 patent/US11584746B2/en active Active
- 2019-02-20 AU AU2019225805A patent/AU2019225805A1/en not_active Abandoned
- 2019-02-20 WO PCT/US2019/018772 patent/WO2019164947A1/en not_active Ceased
- 2019-02-20 CA CA3087716A patent/CA3087716A1/en active Pending
- 2019-02-20 JP JP2020566547A patent/JP7335275B2/ja active Active
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