JP2021514399A5 - - Google Patents
Info
- Publication number
- JP2021514399A5 JP2021514399A5 JP2020566547A JP2020566547A JP2021514399A5 JP 2021514399 A5 JP2021514399 A5 JP 2021514399A5 JP 2020566547 A JP2020566547 A JP 2020566547A JP 2020566547 A JP2020566547 A JP 2020566547A JP 2021514399 A5 JP2021514399 A5 JP 2021514399A5
- Authority
- JP
- Japan
- Prior art keywords
- carbon atoms
- phenyl
- heteroaryl
- membered
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862632817P | 2018-02-20 | 2018-02-20 | |
| US62/632,817 | 2018-02-20 | ||
| US201862744085P | 2018-10-10 | 2018-10-10 | |
| US62/744,085 | 2018-10-10 | ||
| PCT/US2019/018772 WO2019164947A1 (en) | 2018-02-20 | 2019-02-20 | Inhibitors of egfr and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021514399A JP2021514399A (ja) | 2021-06-10 |
| JP2021514399A5 true JP2021514399A5 (https=) | 2022-02-25 |
| JP7335275B2 JP7335275B2 (ja) | 2023-08-29 |
Family
ID=67687389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020566547A Active JP7335275B2 (ja) | 2018-02-20 | 2019-02-20 | Ｅｇｆｒの阻害剤およびその使用法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11584746B2 (https=) |
| EP (1) | EP3755689B1 (https=) |
| JP (1) | JP7335275B2 (https=) |
| AU (1) | AU2019225805A1 (https=) |
| CA (1) | CA3087716A1 (https=) |
| WO (1) | WO2019164947A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210085688A1 (en) * | 2018-02-20 | 2021-03-25 | Dana-Farber Cancer Institute, Inc. | Pharmaceutical combinations of egfr inhibitors and methods of use thereof |
| WO2019164948A1 (en) * | 2018-02-20 | 2019-08-29 | Dana-Farber Cancer Institute, Inc. | Inhibitors of egfr and methods of use thereof |
| AU2019225799A1 (en) * | 2018-02-20 | 2020-07-09 | Dana-Farber Cancer Institute, Inc. | Pharmaceutical combinations of EGFR inhibitors and methods of use thereof |
| WO2024168152A1 (en) * | 2023-02-08 | 2024-08-15 | The Research Foundation For The State University Of New York | Benzodiazepinone-derived inhibitors of egfr and her2 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007056388A2 (en) | 2005-11-07 | 2007-05-18 | The General Hospital Corporation | Compositions and methods for modulating poly (adp-ribose) polymerase activity |
| US20110028458A1 (en) * | 2008-04-11 | 2011-02-03 | Thallion Pharmaceuticals Inc. | Inhibition of cell migration by a farnesylated dibenzodiazepinone |
| JP5752601B2 (ja) | 2008-12-08 | 2015-07-22 | ブイエム ファーマ エルエルシー | タンパク質受容体チロシンキナーゼ阻害薬の組成物 |
| EP3828185B1 (en) | 2009-01-06 | 2024-11-20 | Dana-Farber Cancer Institute, Inc. | Pyrimido-diazepinone kinase scaffold compounds and methods of treating disorders |
| US9156233B2 (en) | 2012-10-22 | 2015-10-13 | Us Floors, Inc. | Engineered waterproof flooring and wall covering planks |
| WO2014160430A1 (en) | 2013-03-13 | 2014-10-02 | Georgetown University | Small molecule lrrk2 and erk5 inhibitors |
| US20170114323A1 (en) | 2014-06-19 | 2017-04-27 | Whitehead Institute For Biomedical Research | Uses of kinase inhibitors for inducing and maintaining pluripotency |
| WO2016201370A1 (en) | 2015-06-12 | 2016-12-15 | Dana-Farber Cancer Institute, Inc. | Combination therapy of transcription inhibitors and kinase inhibitors |
| KR20180132812A (ko) | 2016-04-07 | 2018-12-12 | 다나-파버 캔서 인스티튜트 인크. | 피리미도-디아제피논 키나아제 스캐폴드 화합물 및 ｐｉ3ｋ-매개된 장애의 치료 방법 |
| TW201834651A (zh) | 2016-12-22 | 2018-10-01 | 瑞士商赫孚孟拉羅股份公司 | 化合物 |
| WO2018220149A1 (en) | 2017-06-02 | 2018-12-06 | F. Hoffmann-La Roche Ag | Compounds |
| WO2019164948A1 (en) | 2018-02-20 | 2019-08-29 | Dana-Farber Cancer Institute, Inc. | Inhibitors of egfr and methods of use thereof |
| US20210085688A1 (en) | 2018-02-20 | 2021-03-25 | Dana-Farber Cancer Institute, Inc. | Pharmaceutical combinations of egfr inhibitors and methods of use thereof |
| JP7086272B2 (ja) | 2018-08-16 | 2022-06-17 | コリア リサーチ インスティテュート オブ ケミカル テクノロジー | イソインドリン－１－オン誘導体、同じものを調製する方法、およびがんを予防するまたは処置するための有効な構成要素として同じものを含む医薬組成物 |
-
2019
- 2019-02-20 US US16/970,931 patent/US11584746B2/en active Active
- 2019-02-20 AU AU2019225805A patent/AU2019225805A1/en not_active Abandoned
- 2019-02-20 JP JP2020566547A patent/JP7335275B2/ja active Active
- 2019-02-20 WO PCT/US2019/018772 patent/WO2019164947A1/en not_active Ceased
- 2019-02-20 CA CA3087716A patent/CA3087716A1/en active Pending
- 2019-02-20 EP EP19757550.9A patent/EP3755689B1/en active Active
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