JP2021513990A5 - - Google Patents
Info
- Publication number
- JP2021513990A5 JP2021513990A5 JP2020543847A JP2020543847A JP2021513990A5 JP 2021513990 A5 JP2021513990 A5 JP 2021513990A5 JP 2020543847 A JP2020543847 A JP 2020543847A JP 2020543847 A JP2020543847 A JP 2020543847A JP 2021513990 A5 JP2021513990 A5 JP 2021513990A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- optionally substituted
- unit
- group
- needed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023116253A JP2023129495A (ja) | 2018-02-20 | 2023-07-14 | 疎水性アウリスタチンｆ化合物およびそのコンジュゲート |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862633059P | 2018-02-20 | 2018-02-20 | |
| US62/633,059 | 2018-02-20 | ||
| PCT/US2019/018825 WO2019164987A1 (en) | 2018-02-20 | 2019-02-20 | Hydrophobic auristatin f compounds and conjugates thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023116253A Division JP2023129495A (ja) | 2018-02-20 | 2023-07-14 | 疎水性アウリスタチンｆ化合物およびそのコンジュゲート |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021513990A JP2021513990A (ja) | 2021-06-03 |
| JP2021513990A5 true JP2021513990A5 (https=) | 2022-03-01 |
Family
ID=65904522
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020543847A Pending JP2021513990A (ja) | 2018-02-20 | 2019-02-20 | 疎水性アウリスタチンｆ化合物およびそのコンジュゲート |
| JP2023116253A Pending JP2023129495A (ja) | 2018-02-20 | 2023-07-14 | 疎水性アウリスタチンｆ化合物およびそのコンジュゲート |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023116253A Pending JP2023129495A (ja) | 2018-02-20 | 2023-07-14 | 疎水性アウリスタチンｆ化合物およびそのコンジュゲート |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11857565B2 (https=) |
| EP (1) | EP3755707A1 (https=) |
| JP (2) | JP2021513990A (https=) |
| KR (1) | KR20200122351A (https=) |
| CN (1) | CN111989339A (https=) |
| AU (1) | AU2019225845B2 (https=) |
| CA (1) | CA3090805A1 (https=) |
| IL (1) | IL276546B2 (https=) |
| MX (1) | MX2020008267A (https=) |
| SG (1) | SG11202007540SA (https=) |
| TW (1) | TWI838358B (https=) |
| WO (1) | WO2019164987A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112023018676A2 (pt) | 2021-03-18 | 2023-10-10 | Seagen Inc | Conjugado anticorpo-fármaco, composição farmacêutica, métodos de tratamento de uma doença ou condição e de um câncer, e, composição de conjugado ligante-fármaco |
| US20240209080A1 (en) | 2021-04-10 | 2024-06-27 | Profoundbio Us Co. | Folr1 binding agents, conjugates thereof and methods of using the same |
| CA3216459A1 (en) | 2021-04-23 | 2022-10-27 | Profoundbio Us Co. | Anti-cd70 antibodies, conjugates thereof and methods of using the same |
| TW202320857A (zh) | 2021-07-06 | 2023-06-01 | 美商普方生物製藥美國公司 | 連接子、藥物連接子及其結合物及其使用方法 |
| CN118119409A (zh) | 2021-09-03 | 2024-05-31 | 东丽株式会社 | 癌的治疗和/或预防用药物组合物 |
| AR133955A1 (es) | 2023-09-26 | 2025-11-19 | Profoundbio Us Co | Agentes de unión a ptk7, conjugados de éstos y métodos de uso de los mismos |
| WO2025149661A1 (en) | 2024-01-10 | 2025-07-17 | Genmab A/S | Slitrk6 binding agents, conjugates thereof and methods of using the same |
| US20250381289A1 (en) | 2024-02-29 | 2025-12-18 | Genmab A/S | Egfr and c-met bispecific binding agents, conjugates thereof and methods of using the same |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2036891B (en) | 1978-12-05 | 1983-05-05 | Windsor Smith C | Change speed gear |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| DE3689123T2 (de) | 1985-11-01 | 1994-03-03 | Xoma Corp | Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung. |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| JP4046354B2 (ja) | 1996-03-18 | 2008-02-13 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | 増大した半減期を有する免疫グロブリン様ドメイン |
| JP2001505194A (ja) | 1996-11-05 | 2001-04-17 | ブリストル―マイヤーズ・スクイブ・カンパニー | 分枝ペプチド・リンカー |
| DK1545613T3 (da) * | 2002-07-31 | 2011-11-14 | Seattle Genetics Inc | Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom |
| EP2478912B1 (en) | 2003-11-06 | 2016-08-31 | Seattle Genetics, Inc. | Auristatin conjugates with anti-HER2 or anti-CD22 antibodies and their use in therapy |
| ES2708763T3 (es) | 2005-07-07 | 2019-04-11 | Seattle Genetics Inc | Compuestos de monometilvalina que tienen modificaciones de la cadena lateral de fenilalanina en el extremo C |
| WO2007086083A1 (en) | 2006-01-24 | 2007-08-02 | Tecnoimage Srl | Supporting frame for covering elements |
| US8257706B2 (en) | 2006-08-25 | 2012-09-04 | Seattle Genetics, Inc. | CD30 binding agents and uses thereof |
| AR065404A1 (es) | 2007-02-21 | 2009-06-03 | Medarex Inc | Conjugados farmaco-ligando, los que se unen a citotoxinas potentes, composicion farmaceutica que los contienen y su uso para retardar o detener el crecimiento de un tumor en un mamifero |
| DK2265283T3 (da) | 2008-03-18 | 2014-10-20 | Seattle Genetics Inc | Auristatin-lægemiddel-linker-konjugater |
| EP2648752B1 (en) | 2010-12-06 | 2017-02-15 | Seattle Genetics, Inc. | Humanized antibodies to liv-1 and use of same to treat cancer |
| SG11201404354UA (en) | 2012-02-17 | 2014-10-30 | Seattle Genetics Inc | ANTIBODIES TO INTEGRIN αVβ6 AND USE OF SAME TO TREAT CANCER |
| EP2832856A4 (en) | 2012-03-29 | 2016-01-27 | Chugai Pharmaceutical Co Ltd | ANTI-LAMP5 ANTIBODIES AND USE THEREOF |
| CN104640572B (zh) * | 2012-05-15 | 2018-04-27 | 索伦托医疗有限公司 | 药物偶联物，偶联方法，及其用途 |
| US20130309223A1 (en) | 2012-05-18 | 2013-11-21 | Seattle Genetics, Inc. | CD33 Antibodies And Use Of Same To Treat Cancer |
| CA2937753A1 (en) | 2014-02-17 | 2015-08-20 | Seattle Genetics, Inc. | Hydrophilic antibody-drug conjugates |
-
2019
- 2019-02-20 SG SG11202007540SA patent/SG11202007540SA/en unknown
- 2019-02-20 CA CA3090805A patent/CA3090805A1/en active Pending
- 2019-02-20 JP JP2020543847A patent/JP2021513990A/ja active Pending
- 2019-02-20 IL IL276546A patent/IL276546B2/en unknown
- 2019-02-20 US US16/968,749 patent/US11857565B2/en active Active
- 2019-02-20 MX MX2020008267A patent/MX2020008267A/es unknown
- 2019-02-20 EP EP19713233.5A patent/EP3755707A1/en not_active Withdrawn
- 2019-02-20 AU AU2019225845A patent/AU2019225845B2/en not_active Ceased
- 2019-02-20 TW TW108105691A patent/TWI838358B/zh not_active IP Right Cessation
- 2019-02-20 KR KR1020207026764A patent/KR20200122351A/ko not_active Ceased
- 2019-02-20 CN CN201980025734.6A patent/CN111989339A/zh active Pending
- 2019-02-20 WO PCT/US2019/018825 patent/WO2019164987A1/en not_active Ceased
-
2023
- 2023-07-14 JP JP2023116253A patent/JP2023129495A/ja active Pending
- 2023-11-02 US US18/500,858 patent/US20240216420A1/en not_active Abandoned
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