JP2021513844A5 - - Google Patents

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Publication number
JP2021513844A5
JP2021513844A5 JP2020543351A JP2020543351A JP2021513844A5 JP 2021513844 A5 JP2021513844 A5 JP 2021513844A5 JP 2020543351 A JP2020543351 A JP 2020543351A JP 2020543351 A JP2020543351 A JP 2020543351A JP 2021513844 A5 JP2021513844 A5 JP 2021513844A5
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JP
Japan
Prior art keywords
antibody
occupied
conjugated
item
seq
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2020543351A
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English (en)
Japanese (ja)
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JP7402807B2 (ja
JP2021513844A (ja
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Priority claimed from PCT/US2019/018182 external-priority patent/WO2019161174A1/en
Publication of JP2021513844A publication Critical patent/JP2021513844A/ja
Publication of JP2021513844A5 publication Critical patent/JP2021513844A5/ja
Priority to JP2023067166A priority Critical patent/JP2023089195A/ja
Application granted granted Critical
Publication of JP7402807B2 publication Critical patent/JP7402807B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020543351A 2018-02-15 2019-02-15 グリピカン3抗体およびそのコンジュゲート Active JP7402807B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023067166A JP2023089195A (ja) 2018-02-15 2023-04-17 グリピカン3抗体およびそのコンジュゲート

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862631353P 2018-02-15 2018-02-15
US62/631,353 2018-02-15
PCT/US2019/018182 WO2019161174A1 (en) 2018-02-15 2019-02-15 Glypican 3 antibodies and conjugates thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023067166A Division JP2023089195A (ja) 2018-02-15 2023-04-17 グリピカン3抗体およびそのコンジュゲート

Publications (3)

Publication Number Publication Date
JP2021513844A JP2021513844A (ja) 2021-06-03
JP2021513844A5 true JP2021513844A5 (enExample) 2022-02-22
JP7402807B2 JP7402807B2 (ja) 2023-12-21

Family

ID=67620075

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020543351A Active JP7402807B2 (ja) 2018-02-15 2019-02-15 グリピカン3抗体およびそのコンジュゲート
JP2023067166A Pending JP2023089195A (ja) 2018-02-15 2023-04-17 グリピカン3抗体およびそのコンジュゲート

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023067166A Pending JP2023089195A (ja) 2018-02-15 2023-04-17 グリピカン3抗体およびそのコンジュゲート

Country Status (13)

Country Link
US (2) US11819553B2 (enExample)
EP (1) EP3752534A4 (enExample)
JP (2) JP7402807B2 (enExample)
KR (1) KR20200121317A (enExample)
CN (1) CN111712520A (enExample)
AR (1) AR114112A1 (enExample)
AU (1) AU2019220700A1 (enExample)
CA (1) CA3090251A1 (enExample)
IL (1) IL276514B2 (enExample)
MX (1) MX2020008030A (enExample)
SG (1) SG11202007073SA (enExample)
TW (1) TWI851552B (enExample)
WO (1) WO2019161174A1 (enExample)

Families Citing this family (17)

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Publication number Priority date Publication date Assignee Title
TWI851531B (zh) 2016-08-09 2024-08-11 美商思進公司 具有改善之生理化學性質之具自我穩定連接子之藥物結合物
AR114112A1 (es) 2018-02-15 2020-07-22 Seattle Genetics Inc Anticuerpos de glipicano 3 y conjugados de los mismos
CA3170023A1 (en) * 2020-02-27 2021-09-02 Nanjing Legend Biotech Co., Ltd. Antibodies and chimeric antigen receptors targeting glypican-3 (gpc3) and methods of use thereof
AU2021251875A1 (en) 2020-04-10 2022-11-03 Seagen Inc. Charge variant linkers
MX2022013920A (es) * 2020-05-07 2022-11-30 Phanes Therapeutics Inc Anticuerpos anti-antigeno asociado con tumor y usos de los mismos.
BR112023018676A2 (pt) 2021-03-18 2023-10-10 Seagen Inc Conjugado anticorpo-fármaco, composição farmacêutica, métodos de tratamento de uma doença ou condição e de um câncer, e, composição de conjugado ligante-fármaco
CN112921005B (zh) * 2021-04-14 2023-07-07 中国农业科学院兰州兽医研究所 一株杂交瘤细胞株及其产生的犬细小病毒vp2蛋白单克隆抗体和应用
AU2022283467A1 (en) 2021-05-28 2023-12-07 Seagen Inc. Anthracycline antibody conjugates
WO2023023354A2 (en) * 2021-08-19 2023-02-23 Adicet Therapeutics, Inc. Methods for detection of membrane bound glypican-3
WO2023045151A1 (en) * 2021-09-24 2023-03-30 Zhejiang Shimai Pharmaceutical Co., Ltd. Antibodies against gpc3 and uses thereof
WO2023178289A2 (en) 2022-03-17 2023-09-21 Seagen Inc. Camptothecin conjugates
WO2023207475A1 (zh) * 2022-04-24 2023-11-02 昱言科技(北京)有限公司 靶向gpc3的单克隆抗体和包含此抗体的抗体药物缀合物
EP4591887A1 (en) * 2022-09-22 2025-07-30 Lepu Biopharma Co., Ltd. Gpc3 antibody-drug conjugate and use thereof
CN119968398A (zh) * 2022-11-28 2025-05-09 四川科伦博泰生物医药股份有限公司 靶向gpc3的抗体及其用途
WO2024129756A1 (en) 2022-12-13 2024-06-20 Seagen Inc. Site-specific engineered cysteine antibody drug conjugates
CN119424671A (zh) * 2023-08-01 2025-02-14 上海新理念生物医药科技有限公司 含糖基吡啶型连接子的抗体药物偶联物
AR134171A1 (es) 2023-10-24 2025-12-10 Seagen Inc Compuestos quimioterapéuticos y métodos de uso

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7361336B1 (en) 1997-09-18 2008-04-22 Ivan Bergstein Methods of cancer therapy targeted against a cancer stem line
KR100953520B1 (ko) 2001-06-22 2010-04-21 츄가이 세이야꾸 가부시키가이샤 항글리피칸 3항체를 포함하는 항암제
WO2004022597A1 (ja) 2002-09-04 2004-03-18 Chugai Seiyaku Kabushiki Kaisha Gpc3の血中可溶化n端ペプチドに対する抗体
SI1674111T1 (sl) * 2004-07-09 2011-02-28 Chugai Pharmaceutical Co Ltd Protitelo proti glipikanu 3
JP2013511994A (ja) * 2009-11-30 2013-04-11 バイオテスト・アクチエンゲゼルシヤフト 全身性エリテマトーデス(sle)を治療するためのヒト化抗il−10抗体
JP6827319B2 (ja) * 2014-05-08 2021-02-10 中外製薬株式会社 Gpc3標的治療剤療法が有効である患者に投与されるgpc3標的治療剤
WO2015179658A2 (en) * 2014-05-22 2015-11-26 Genentech, Inc. Anti-gpc3 antibodies and immunoconjugates
EP2963057A1 (en) * 2014-07-02 2016-01-06 Calypso Biotech SA Antibodies to IL-15
FI3900742T3 (fi) * 2014-09-11 2024-08-16 Seagen Inc Tertiääristä amiinia sisältävien lääkeaineiden kohdennettu antaminen
WO2017181109A1 (en) * 2016-04-15 2017-10-19 Michael Molloy Anti-human vista antibodies and use thereof
US20170326249A1 (en) * 2016-05-10 2017-11-16 Bristol-Myers Squibb Company Antibody-drug conjugate of an anti-glypican-3 antibody and a tubulysin analog, preparation and uses
AR114112A1 (es) 2018-02-15 2020-07-22 Seattle Genetics Inc Anticuerpos de glipicano 3 y conjugados de los mismos

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