JP2021513844A5 - - Google Patents

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Publication number
JP2021513844A5
JP2021513844A5 JP2020543351A JP2020543351A JP2021513844A5 JP 2021513844 A5 JP2021513844 A5 JP 2021513844A5 JP 2020543351 A JP2020543351 A JP 2020543351A JP 2020543351 A JP2020543351 A JP 2020543351A JP 2021513844 A5 JP2021513844 A5 JP 2021513844A5
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JP
Japan
Prior art keywords
antibody
occupied
conjugated
item
seq
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Application number
JP2020543351A
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English (en)
Japanese (ja)
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JP7402807B2 (ja
JP2021513844A (ja
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Priority claimed from PCT/US2019/018182 external-priority patent/WO2019161174A1/en
Publication of JP2021513844A publication Critical patent/JP2021513844A/ja
Publication of JP2021513844A5 publication Critical patent/JP2021513844A5/ja
Priority to JP2023067166A priority Critical patent/JP2023089195A/ja
Application granted granted Critical
Publication of JP7402807B2 publication Critical patent/JP7402807B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020543351A 2018-02-15 2019-02-15 グリピカン3抗体およびそのコンジュゲート Active JP7402807B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023067166A JP2023089195A (ja) 2018-02-15 2023-04-17 グリピカン3抗体およびそのコンジュゲート

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862631353P 2018-02-15 2018-02-15
US62/631,353 2018-02-15
PCT/US2019/018182 WO2019161174A1 (en) 2018-02-15 2019-02-15 Glypican 3 antibodies and conjugates thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023067166A Division JP2023089195A (ja) 2018-02-15 2023-04-17 グリピカン3抗体およびそのコンジュゲート

Publications (3)

Publication Number Publication Date
JP2021513844A JP2021513844A (ja) 2021-06-03
JP2021513844A5 true JP2021513844A5 (enExample) 2022-02-22
JP7402807B2 JP7402807B2 (ja) 2023-12-21

Family

ID=67620075

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020543351A Active JP7402807B2 (ja) 2018-02-15 2019-02-15 グリピカン3抗体およびそのコンジュゲート
JP2023067166A Pending JP2023089195A (ja) 2018-02-15 2023-04-17 グリピカン3抗体およびそのコンジュゲート

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023067166A Pending JP2023089195A (ja) 2018-02-15 2023-04-17 グリピカン3抗体およびそのコンジュゲート

Country Status (13)

Country Link
US (2) US11819553B2 (enExample)
EP (1) EP3752534A4 (enExample)
JP (2) JP7402807B2 (enExample)
KR (1) KR20200121317A (enExample)
CN (1) CN111712520A (enExample)
AR (1) AR114112A1 (enExample)
AU (1) AU2019220700A1 (enExample)
CA (1) CA3090251A1 (enExample)
IL (1) IL276514B2 (enExample)
MX (1) MX2020008030A (enExample)
SG (1) SG11202007073SA (enExample)
TW (1) TWI851552B (enExample)
WO (1) WO2019161174A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240010534A (ko) 2016-08-09 2024-01-23 씨젠 인크. 개선된 물리화학적 특성을 갖는 자기 안정화 링커를 구비한 약물 접합체
AR114112A1 (es) 2018-02-15 2020-07-22 Seattle Genetics Inc Anticuerpos de glipicano 3 y conjugados de los mismos
JP7747645B2 (ja) * 2020-02-27 2025-10-01 レジェンド バイオテック アイルランド リミテッド グリピカン-3(gpc3)を標的化する抗体及びキメラ抗原受容体並びにその使用方法
AU2021251875A1 (en) 2020-04-10 2022-11-03 Seagen Inc. Charge variant linkers
MX2022013920A (es) * 2020-05-07 2022-11-30 Phanes Therapeutics Inc Anticuerpos anti-antigeno asociado con tumor y usos de los mismos.
JP2024510435A (ja) 2021-03-18 2024-03-07 シージェン インコーポレイテッド 生体活性化合物の内部移行複合体からの選択的薬物放出
CN112921005B (zh) * 2021-04-14 2023-07-07 中国农业科学院兰州兽医研究所 一株杂交瘤细胞株及其产生的犬细小病毒vp2蛋白单克隆抗体和应用
IL308795A (en) 2021-05-28 2024-01-01 Seagen Inc Anthracycline antibody conjugates
WO2023023354A2 (en) * 2021-08-19 2023-02-23 Adicet Therapeutics, Inc. Methods for detection of membrane bound glypican-3
WO2023045151A1 (en) * 2021-09-24 2023-03-30 Zhejiang Shimai Pharmaceutical Co., Ltd. Antibodies against gpc3 and uses thereof
KR20250004952A (ko) 2022-03-17 2025-01-08 씨젠 인크. 캄프토테신 접합체
WO2023207475A1 (zh) * 2022-04-24 2023-11-02 昱言科技(北京)有限公司 靶向gpc3的单克隆抗体和包含此抗体的抗体药物缀合物
WO2024061305A1 (zh) * 2022-09-22 2024-03-28 上海美雅珂生物技术有限责任公司 Gpc3抗体药物偶联物及其应用
CN119968398A (zh) * 2022-11-28 2025-05-09 四川科伦博泰生物医药股份有限公司 靶向gpc3的抗体及其用途
WO2024129756A1 (en) 2022-12-13 2024-06-20 Seagen Inc. Site-specific engineered cysteine antibody drug conjugates
CN119424671A (zh) * 2023-08-01 2025-02-14 上海新理念生物医药科技有限公司 含糖基吡啶型连接子的抗体药物偶联物
TW202535940A (zh) 2023-10-24 2025-09-16 美商思進公司 化學治療化合物及使用方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7361336B1 (en) 1997-09-18 2008-04-22 Ivan Bergstein Methods of cancer therapy targeted against a cancer stem line
EP1411118B1 (en) 2001-06-22 2008-09-03 Chugai Seiyaku Kabushiki Kaisha Cell proliferation inhibitors containing anti-glypican-3 antibody
WO2004022597A1 (ja) 2002-09-04 2004-03-18 Chugai Seiyaku Kabushiki Kaisha Gpc3の血中可溶化n端ペプチドに対する抗体
AU2005256113B2 (en) 2004-07-09 2011-02-10 Chugai Seiyaku Kabushiki Kaisha Anti-glypican 3 antibody
AU2010323037B2 (en) * 2009-11-30 2015-01-29 Biotest Ag Humanized anti-IL-10 antibodies for the treatment of systemic lupus erythematosus (SLE)
KR102409014B1 (ko) * 2014-05-08 2022-06-14 추가이 세이야쿠 가부시키가이샤 Gpc3 표적 치료제 요법이 유효한 환자에게 투여되는 gpc3 표적 치료제
JP2017522861A (ja) 2014-05-22 2017-08-17 ジェネンテック, インコーポレイテッド 抗gpc3抗体及びイムノコンジュゲート
EP2963057A1 (en) 2014-07-02 2016-01-06 Calypso Biotech SA Antibodies to IL-15
HRP20241124T1 (hr) 2014-09-11 2024-11-22 Seagen Inc. Ciljana isporuka lijekovitih tvari koje sadrže tercijarni amin
WO2017181109A1 (en) 2016-04-15 2017-10-19 Michael Molloy Anti-human vista antibodies and use thereof
US20170326249A1 (en) 2016-05-10 2017-11-16 Bristol-Myers Squibb Company Antibody-drug conjugate of an anti-glypican-3 antibody and a tubulysin analog, preparation and uses
AR114112A1 (es) 2018-02-15 2020-07-22 Seattle Genetics Inc Anticuerpos de glipicano 3 y conjugados de los mismos

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