JP2023504187A5 - - Google Patents

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Publication number
JP2023504187A5
JP2023504187A5 JP2022533071A JP2022533071A JP2023504187A5 JP 2023504187 A5 JP2023504187 A5 JP 2023504187A5 JP 2022533071 A JP2022533071 A JP 2022533071A JP 2022533071 A JP2022533071 A JP 2022533071A JP 2023504187 A5 JP2023504187 A5 JP 2023504187A5
Authority
JP
Japan
Prior art keywords
antibody
amino acid
acid sequence
antigen
binding fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022533071A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023504187A (ja
JP7551750B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/063390 external-priority patent/WO2021113697A1/en
Publication of JP2023504187A publication Critical patent/JP2023504187A/ja
Publication of JP2023504187A5 publication Critical patent/JP2023504187A5/ja
Priority to JP2024151893A priority Critical patent/JP2024170517A/ja
Application granted granted Critical
Publication of JP7551750B2 publication Critical patent/JP7551750B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022533071A 2019-12-05 2020-12-04 抗αvβ6抗体及び抗体薬物コンジュゲート Active JP7551750B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024151893A JP2024170517A (ja) 2019-12-05 2024-09-04 抗αvβ6抗体及び抗体薬物コンジュゲート

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962943959P 2019-12-05 2019-12-05
US62/943,959 2019-12-05
US202063012584P 2020-04-20 2020-04-20
US63/012,584 2020-04-20
PCT/US2020/063390 WO2021113697A1 (en) 2019-12-05 2020-12-04 Anti-avb6 antibodies and antibody-drug conjugates

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024151893A Division JP2024170517A (ja) 2019-12-05 2024-09-04 抗αvβ6抗体及び抗体薬物コンジュゲート

Publications (3)

Publication Number Publication Date
JP2023504187A JP2023504187A (ja) 2023-02-01
JP2023504187A5 true JP2023504187A5 (enExample) 2024-06-07
JP7551750B2 JP7551750B2 (ja) 2024-09-17

Family

ID=76222033

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022533071A Active JP7551750B2 (ja) 2019-12-05 2020-12-04 抗αvβ6抗体及び抗体薬物コンジュゲート
JP2024151893A Withdrawn JP2024170517A (ja) 2019-12-05 2024-09-04 抗αvβ6抗体及び抗体薬物コンジュゲート

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024151893A Withdrawn JP2024170517A (ja) 2019-12-05 2024-09-04 抗αvβ6抗体及び抗体薬物コンジュゲート

Country Status (11)

Country Link
US (3) US11827709B2 (enExample)
EP (1) EP4069297A4 (enExample)
JP (2) JP7551750B2 (enExample)
KR (1) KR20220110231A (enExample)
AU (1) AU2020397070A1 (enExample)
BR (1) BR112022009570A2 (enExample)
CA (1) CA3159414A1 (enExample)
IL (1) IL293195A (enExample)
MX (1) MX2022006132A (enExample)
TW (1) TWI884192B (enExample)
WO (1) WO2021113697A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11827709B2 (en) 2019-12-05 2023-11-28 Seagen Inc. Anti-AVB6 antibodies and antibody-drug conjugates
BR112023018676A2 (pt) 2021-03-18 2023-10-10 Seagen Inc Conjugado anticorpo-fármaco, composição farmacêutica, métodos de tratamento de uma doença ou condição e de um câncer, e, composição de conjugado ligante-fármaco
KR20250089558A (ko) 2022-11-03 2025-06-18 씨젠 인크. 항-αvβ6 항체 및 항체-약물 접합체 및 암 치료에서의 이의 용도
WO2024129756A1 (en) 2022-12-13 2024-06-20 Seagen Inc. Site-specific engineered cysteine antibody drug conjugates
EP4731670A2 (en) 2023-06-23 2026-04-29 Mythic Therapeutics, Inc. Ph sensitive anti-itgb6 antibodies and uses thereof
AU2024346987A1 (en) * 2023-09-19 2026-04-02 Telix Targeting Technologies, Inc. Antigen binding constructs
WO2026011013A1 (en) 2024-07-02 2026-01-08 Epibiologics, Inc. Binding agents and uses thereof

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US5962643A (en) 1991-07-11 1999-10-05 The Regents Of The University Of California Integrin β subunit and uses thereof
ATE511850T1 (de) 1997-08-08 2011-06-15 Univ California Behandlung von blasenfibrose mit antikörpern gegen alpha-v-beta-6-integrin
EP2165714B1 (en) 2001-04-30 2013-10-23 Eli Lilly And Company Humanized antibodies recognizing the beta-amyloid peptide
NZ535425A (en) 2002-03-13 2008-05-30 Biogen Idec Inc Anti-alphavbeta6 antibodies
CA2481922A1 (en) 2002-04-12 2003-10-23 Raven Biotechnologies, Inc. Antibodies that bind to integrin alpha-v-beta-6 and methods of use thereof
US7241598B2 (en) 2004-06-29 2007-07-10 The Chinese University Of Hong Kong Frame-shifting PCR for germline immunoglobulin genes retrieval and antibody engineering
AU2005294131A1 (en) 2004-10-05 2006-04-20 Wyeth Methods and compositions for improving recombinant protein production
EP1861425B1 (en) 2005-03-10 2012-05-16 Morphotek, Inc. Anti-mesothelin antibodies
WO2006125140A2 (en) 2005-05-18 2006-11-23 Biogen Idec Inc. Methods for treating fibrotic conditions
CN104072614B (zh) * 2005-07-08 2017-04-26 生物基因Ma公司 抗-αvβ6 抗体及其用途
AU2006286498A1 (en) 2005-08-31 2007-03-08 Novo Nordisk Health Care Ag Human FVII monoclonal antibodies binding the GLA domain and use thereof
CN101563105B (zh) 2006-07-10 2013-01-23 拜奥根Idec马萨诸塞公司 用于抑制smad4-缺陷癌症的组合物和方法
EP2064244B1 (en) 2006-08-03 2019-06-05 MedImmune Limited ANTIBODIES DIRECTED TO alphaVbeta6 AND USES THEREOF
JP2010506944A (ja) 2006-10-19 2010-03-04 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア インテグリンαVβ6のアンタゴニストを用いる慢性喘息の処置および予防
CL2008001071A1 (es) * 2007-04-17 2009-05-22 Smithkline Beecham Corp Metodo para obtener anticuerpo penta-especifico contra il-8/cxcl8, gro-alfa/cxcl1, gro-beta/cxcl2), gro-gama/cxcl3 y ena-78/cxcl5 humanas; anticuerpo penta-especifico; proceso de produccion del mismo; vector, hbridoma o celela que lo comprende; composicion farmceutica; uso para tratar copd, otras enfermedades.
EP2241578B1 (en) 2008-01-11 2016-04-20 The University of Tokyo Anti-cldn6 antibody
JP5467997B2 (ja) 2008-03-27 2014-04-09 テルモ株式会社 生体吸収性材料およびそれを用いた生体内留置物
CA2723842A1 (en) 2008-05-09 2009-11-12 Peter Vanlandschoot Amino acid sequences directed against integrins and uses thereof
CN102597001B (zh) 2009-08-19 2014-07-30 默克专利有限公司 在ffpe材料中用于检测整联蛋白复合体的抗体
WO2011046309A2 (en) 2009-10-12 2011-04-21 Korea Research Institute Of Bioscience And Biotechnology A diagnostic marker for hepatocellular carcinoma comprising anti-fasn autoantibodies and a diagnostic composition for hepatocellular carcinoma comprising antigens thereof
SG191716A1 (en) * 2010-11-19 2013-08-30 Toshio Imai Neutralizing anti-ccl20 antibodies
SG11201404354UA (en) * 2012-02-17 2014-10-30 Seattle Genetics Inc ANTIBODIES TO INTEGRIN αVβ6 AND USE OF SAME TO TREAT CANCER
HK1208470A1 (en) 2012-03-29 2016-03-04 Biogen Ma Inc. Biomarkers for use in integrin therapy applications
WO2014144466A1 (en) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Anti-alpha v beta 6 antibodies and uses thereof
WO2014143739A2 (en) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Anti-alpha v beta 6 antibodies and uses thereof
HK1221725A1 (zh) * 2013-08-13 2017-06-09 Sanofi 纤溶酶原激活剂抑制剂-1(pai-1)的抗体及其用途
CA2925057A1 (en) 2013-10-01 2015-04-09 Simon T. BARRY Methods of treating and diagnosing alpha-v-beta-6 overexpressing cancer
US10858427B2 (en) * 2017-03-10 2020-12-08 Suzhou Kanova Biopharmaceutical Co., Ltd. Monoclonal antibody against both IL-17A and IL-17F and use of the same
JP7325339B2 (ja) * 2017-05-30 2023-08-14 チョン クン ダン ファーマシューティカル コーポレーション 新規な抗c-Met抗体およびその用途
AU2018322475A1 (en) 2017-08-22 2020-03-05 Biogen Ma Inc. Pharmaceutical compositions and dosage regimens containing anti-alpha(v)beta(6) antibodies
GB201814562D0 (en) * 2018-09-07 2018-10-24 Hummingbird Bioscience Pte Ltd Vista antigen-binding molecules
US11827709B2 (en) 2019-12-05 2023-11-28 Seagen Inc. Anti-AVB6 antibodies and antibody-drug conjugates

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