|
JP3050424B2
(ja)
|
1991-07-12 |
2000-06-12 |
塩野義製薬株式会社 |
ヒトエンドセリンリセプター
|
|
US6214345B1
(en)
|
1993-05-14 |
2001-04-10 |
Bristol-Myers Squibb Co. |
Lysosomal enzyme-cleavable antitumor drug conjugates
|
|
US5773223A
(en)
|
1993-09-02 |
1998-06-30 |
Chiron Corporation |
Endothelin B1, (ETB1) receptor polypeptide and its encoding nucleic acid methods, and uses thereof
|
|
US7566452B1
(en)
|
1999-05-04 |
2009-07-28 |
New York University |
Cancer treatment with endothelin receptor antagonists
|
|
US6545048B1
(en)
|
1999-06-29 |
2003-04-08 |
California Institute Of Technology |
Compositions and methods of treating cancer using compositions comprising an inhibitor or endothelin receptor activity
|
|
US7303749B1
(en)
|
1999-10-01 |
2007-12-04 |
Immunogen Inc. |
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
|
|
HK1049787B
(en)
|
1999-10-01 |
2014-07-25 |
Immunogen, Inc. |
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
|
|
AU2001268471A1
(en)
|
2000-06-16 |
2002-01-02 |
Incyte Genomics, Inc. |
G-protein coupled receptors
|
|
WO2002061087A2
(en)
|
2000-12-19 |
2002-08-08 |
Lifespan Biosciences, Inc. |
Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides
|
|
US20030092013A1
(en)
|
2001-08-16 |
2003-05-15 |
Vitivity, Inc. |
Diagnosis and treatment of vascular disease
|
|
WO2003025138A2
(en)
|
2001-09-17 |
2003-03-27 |
Protein Design Labs, Inc. |
Methods of diagnosis of cancer compositions and methods of screening for modulators of cancer
|
|
US20050276812A1
(en)
|
2004-06-01 |
2005-12-15 |
Genentech, Inc. |
Antibody-drug conjugates and methods
|
|
DK1545613T3
(da)
|
2002-07-31 |
2011-11-14 |
Seattle Genetics Inc |
Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom
|
|
WO2004048938A2
(en)
|
2002-11-26 |
2004-06-10 |
Protein Design Labs, Inc. |
Methods of detecting soft tissue sarcoma, compositions and methods of screening for soft tissue sarcoma modulators
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
WO2005035754A1
(ja)
|
2003-10-14 |
2005-04-21 |
Chugai Seiyaku Kabushiki Kaisha |
機能蛋白質を代替する二重特異性抗体
|
|
CN107213469A
(zh)
|
2003-11-06 |
2017-09-29 |
西雅图基因公司 |
能够与配体偶联的单甲基缬氨酸化合物
|
|
EP1718667B1
(en)
|
2004-02-23 |
2013-01-09 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
|
WO2005095972A2
(en)
|
2004-03-19 |
2005-10-13 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with g protein-coupled receptor etb (etb)
|
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
|
KR101270829B1
(ko)
|
2004-09-23 |
2013-06-07 |
제넨테크, 인크. |
시스테인 유전자조작 항체 및 접합체
|
|
US20060094676A1
(en)
|
2004-10-29 |
2006-05-04 |
Ronit Lahav |
Compositions and methods for treating cancer using compositions comprising an inhibitor of endothelin receptor activity
|
|
US20070134243A1
(en)
|
2004-12-01 |
2007-06-14 |
Gazzard Lewis J |
Antibody drug conjugates and methods
|
|
EP1817059A2
(en)
|
2004-12-01 |
2007-08-15 |
Genentech, Inc. |
Conjugates of 1,8-bis-naphthalimides with an antibody
|
|
US20070020657A1
(en)
|
2005-05-20 |
2007-01-25 |
Grebe Stefan K |
Methods for detecting circulating tumor cells
|
|
DE602006021205D1
(de)
|
2005-10-07 |
2011-05-19 |
Exelixis Inc |
Azetidine als mek-inhibitoren bei der behandlung proliferativer erkrankungen
|
|
US20090226465A1
(en)
|
2005-10-31 |
2009-09-10 |
Jackson David Y |
Macrocyclic depsipeptide antibody-drug conjugates and methods
|
|
US7750116B1
(en)
*
|
2006-02-18 |
2010-07-06 |
Seattle Genetics, Inc. |
Antibody drug conjugate metabolites
|
|
US20070269442A1
(en)
|
2006-05-19 |
2007-11-22 |
Robert J. Webber |
Chimeric monoclonal antibody recognizing iNOS
|
|
CL2008002083A1
(es)
*
|
2007-07-16 |
2008-11-21 |
Genentech Inc |
Anticuerpo humanizado anti-cd79b/igbeta/b29; inmunoconjugado; metodo in vitro para determinar presencia de cd79b, inhibir crecimiento de celula con cd79b, o para detectara celula b; metodo para elaborar dicho anticyerpo humanizado; acido nucleico; celula huesped; composicion; metodo de elaboracion de inmunoconjugado; uso medico
|
|
ES2547552T3
(es)
*
|
2008-02-01 |
2015-10-07 |
Genentech, Inc. |
Metabolito de nemorrubicina y reactivos análogos, conjugados anticuerpo-fármaco y métodos
|
|
RU2508110C2
(ru)
|
2008-07-11 |
2014-02-27 |
Новартис Аг |
КОМБИНАЦИЯ (А) ИНГИБИТОРА ФОСФОИНОЗИТ-3-КИНАЗЫ И (Б) МОДУЛЯТОРА ПУТИ Ras/Raf/Mek
|
|
JP6067222B2
(ja)
*
|
2008-07-15 |
2017-01-25 |
ジェネンテック， インコーポレイテッド |
アントラサイクリン誘導体コンジュゲート、その調製方法及び抗腫瘍化合物としてのその用途
|
|
CN102333548B
(zh)
|
2009-02-27 |
2013-01-30 |
健泰科生物技术公司 |
用于蛋白质标记的方法和组合物
|
|
US20110086837A1
(en)
|
2009-10-12 |
2011-04-14 |
Genentech, Inc. |
Combinations of a pi3k inhibitor and a mek inhibitor
|
|
CA2787657A1
(en)
*
|
2010-02-23 |
2011-09-01 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
MX336540B
(es)
|
2010-06-08 |
2016-01-22 |
Genentech Inc |
Conjugados y anticuerpos manipulados geneticamente con cisteina.
|
|
FR2965810B1
(fr)
*
|
2010-10-06 |
2012-12-28 |
Commissariat Energie Atomique |
Anticorps antagoniste du sous-type b des recepteurs aux endothelines et ses utilisations
|
|
ES2544608T3
(es)
|
2010-11-17 |
2015-09-02 |
Genentech, Inc. |
Conjugados de anticuerpo y de alaninil-maitansinol
|
|
BR112013013127B1
(pt)
|
2010-12-02 |
2021-06-22 |
Nerviano Medical Sciences S.R.L. |
Processo para a preparação de derivados de morfolinil antraciclina, compostos derivados de morfolinil antraciclina e composição farmacêutica compreendendo estes compostos
|
|
JP6242865B2
(ja)
*
|
2012-05-01 |
2017-12-06 |
ジェネンテック， インコーポレイテッド |
抗ｐｍｅｌ１７抗体および免疫複合体
|