|
JP3050424B2
(ja)
|
1991-07-12 |
2000-06-12 |
塩野義製薬株式会社 |
ヒトエンドセリンリセプター
|
|
US6214345B1
(en)
|
1993-05-14 |
2001-04-10 |
Bristol-Myers Squibb Co. |
Lysosomal enzyme-cleavable antitumor drug conjugates
|
|
US5773223A
(en)
|
1993-09-02 |
1998-06-30 |
Chiron Corporation |
Endothelin B1, (ETB1) receptor polypeptide and its encoding nucleic acid methods, and uses thereof
|
|
US7566452B1
(en)
|
1999-05-04 |
2009-07-28 |
New York University |
Cancer treatment with endothelin receptor antagonists
|
|
US6545048B1
(en)
|
1999-06-29 |
2003-04-08 |
California Institute Of Technology |
Compositions and methods of treating cancer using compositions comprising an inhibitor or endothelin receptor activity
|
|
US7303749B1
(en)
|
1999-10-01 |
2007-12-04 |
Immunogen Inc. |
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
|
|
CA2385528C
(en)
|
1999-10-01 |
2013-12-10 |
Immunogen, Inc. |
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
|
|
AU2001268471A1
(en)
|
2000-06-16 |
2002-01-02 |
Incyte Genomics, Inc. |
G-protein coupled receptors
|
|
WO2002061087A2
(en)
|
2000-12-19 |
2002-08-08 |
Lifespan Biosciences, Inc. |
Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides
|
|
US20030092013A1
(en)
|
2001-08-16 |
2003-05-15 |
Vitivity, Inc. |
Diagnosis and treatment of vascular disease
|
|
WO2003025138A2
(en)
|
2001-09-17 |
2003-03-27 |
Protein Design Labs, Inc. |
Methods of diagnosis of cancer compositions and methods of screening for modulators of cancer
|
|
ES2544527T3
(es)
|
2002-07-31 |
2015-09-01 |
Seattle Genetics, Inc. |
Conjugados de fármacos y su uso para tratar el cáncer, una enfermedad autoinmune o una enfermedad infecciosa
|
|
US20040253606A1
(en)
|
2002-11-26 |
2004-12-16 |
Protein Design Labs, Inc. |
Methods of detecting soft tissue sarcoma, compositions and methods of screening for soft tissue sarcoma modulators
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
WO2005035754A1
(ja)
|
2003-10-14 |
2005-04-21 |
Chugai Seiyaku Kabushiki Kaisha |
機能蛋白質を代替する二重特異性抗体
|
|
EP3434275A1
(en)
|
2003-11-06 |
2019-01-30 |
Seattle Genetics, Inc. |
Assay for cancer cells based on the use of auristatin conjugates with antibodies
|
|
EP1718667B1
(en)
|
2004-02-23 |
2013-01-09 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
|
WO2005095972A2
(en)
|
2004-03-19 |
2005-10-13 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with g protein-coupled receptor etb (etb)
|
|
MXPA06014065A
(es)
|
2004-06-01 |
2007-01-31 |
Genentech Inc |
Conjugados de droga-anticuerpo y metodos.
|
|
US20100111856A1
(en)
*
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
|
ES2579805T3
(es)
|
2004-09-23 |
2016-08-16 |
Genentech, Inc. |
Anticuerpos y conjugados modificados por ingeniería genética con cisteína
|
|
US20060094676A1
(en)
|
2004-10-29 |
2006-05-04 |
Ronit Lahav |
Compositions and methods for treating cancer using compositions comprising an inhibitor of endothelin receptor activity
|
|
US20070134243A1
(en)
|
2004-12-01 |
2007-06-14 |
Gazzard Lewis J |
Antibody drug conjugates and methods
|
|
JP4993645B2
(ja)
|
2004-12-01 |
2012-08-08 |
ジェネンテック， インコーポレイテッド |
抗体薬剤結合体および方法
|
|
US20070020657A1
(en)
|
2005-05-20 |
2007-01-25 |
Grebe Stefan K |
Methods for detecting circulating tumor cells
|
|
CN103524392B
(zh)
|
2005-10-07 |
2018-06-01 |
埃克塞利希斯股份有限公司 |
作为用于治疗增生性疾病的mek 抑制剂的吖丁啶
|
|
WO2007100385A2
(en)
|
2005-10-31 |
2007-09-07 |
Genentech, Inc. |
Macrocyclic depsipeptide antibody-drug conjugates and methods
|
|
US7750116B1
(en)
*
|
2006-02-18 |
2010-07-06 |
Seattle Genetics, Inc. |
Antibody drug conjugate metabolites
|
|
US20070269442A1
(en)
|
2006-05-19 |
2007-11-22 |
Robert J. Webber |
Chimeric monoclonal antibody recognizing iNOS
|
|
ES2528922T3
(es)
|
2007-07-16 |
2015-02-13 |
Genentech, Inc. |
Anticuerpos anti-CD79b humanizados e inmunoconjugados y métodos de uso
|
|
US8742076B2
(en)
*
|
2008-02-01 |
2014-06-03 |
Genentech, Inc. |
Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods
|
|
CA2729914A1
(en)
|
2008-07-11 |
2010-01-14 |
Novartis Ag |
Combination of (a) a phosphoinositide 3-kinase inhibitor and (b) a modulator of ras/raf/mek pathway
|
|
WO2010009124A2
(en)
*
|
2008-07-15 |
2010-01-21 |
Genentech, Inc. |
Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds
|
|
SG173812A1
(en)
|
2009-02-27 |
2011-09-29 |
Genentech Inc |
Methods and compositions for protein labelling
|
|
NZ599939A
(en)
|
2009-10-12 |
2014-02-28 |
Hoffmann La Roche |
Combinations of a pi3k inhibitor and a mek inhibitor
|
|
NZ601293A
(en)
*
|
2010-02-23 |
2014-10-31 |
Genentech Inc |
Compositions and methods for the diagnosis and treatment of tumor
|
|
SG185428A1
(en)
|
2010-06-08 |
2012-12-28 |
Genentech Inc |
Cysteine engineered antibodies and conjugates
|
|
FR2965810B1
(fr)
*
|
2010-10-06 |
2012-12-28 |
Commissariat Energie Atomique |
Anticorps antagoniste du sous-type b des recepteurs aux endothelines et ses utilisations
|
|
WO2012074757A1
(en)
|
2010-11-17 |
2012-06-07 |
Genentech, Inc. |
Alaninyl maytansinol antibody conjugates
|
|
ES2533710T3
(es)
|
2010-12-02 |
2015-04-14 |
Nerviano Medical Sciences S.R.L. |
Proceso para la preparación de derivados de morfolinil antraciclina
|
|
BR112014027166A2
(pt)
*
|
2012-05-01 |
2017-06-27 |
Genentech Inc |
anticorpo, ácido nucleico, célula hospedeira, método para produzir um anticorpo, imunoconjugado, formulação farmacêutica, método de tratamento, método de inibir proliferação e métodos de detecção.
|