JP2021512888A5 - - Google Patents

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Publication number
JP2021512888A5
JP2021512888A5 JP2020542436A JP2020542436A JP2021512888A5 JP 2021512888 A5 JP2021512888 A5 JP 2021512888A5 JP 2020542436 A JP2020542436 A JP 2020542436A JP 2020542436 A JP2020542436 A JP 2020542436A JP 2021512888 A5 JP2021512888 A5 JP 2021512888A5
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JP
Japan
Prior art keywords
chlorophenyl
piperazine
continuously
reaction vessel
group
Prior art date
Application number
JP2020542436A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021512888A (ja
JPWO2019154770A5 (https=
JP7301858B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2019/052690 external-priority patent/WO2019154770A1/en
Publication of JP2021512888A publication Critical patent/JP2021512888A/ja
Publication of JPWO2019154770A5 publication Critical patent/JPWO2019154770A5/ja
Publication of JP2021512888A5 publication Critical patent/JP2021512888A5/ja
Application granted granted Critical
Publication of JP7301858B2 publication Critical patent/JP7301858B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020542436A 2018-02-07 2019-02-05 トラゾドンの調製のための継続的なプロセス Active JP7301858B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18155470 2018-02-07
EP18155470.0 2018-02-07
PCT/EP2019/052690 WO2019154770A1 (en) 2018-02-07 2019-02-05 Continuous process for the preparation of trazodone

Publications (4)

Publication Number Publication Date
JP2021512888A JP2021512888A (ja) 2021-05-20
JPWO2019154770A5 JPWO2019154770A5 (https=) 2022-02-04
JP2021512888A5 true JP2021512888A5 (https=) 2022-02-04
JP7301858B2 JP7301858B2 (ja) 2023-07-03

Family

ID=61187146

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020542436A Active JP7301858B2 (ja) 2018-02-07 2019-02-05 トラゾドンの調製のための継続的なプロセス

Country Status (27)

Country Link
US (1) US12221438B2 (https=)
EP (1) EP3749668B1 (https=)
JP (1) JP7301858B2 (https=)
KR (1) KR102646651B1 (https=)
CN (1) CN111886235B (https=)
AU (1) AU2019217490B2 (https=)
BR (1) BR112020015885A2 (https=)
CA (1) CA3089552A1 (https=)
CY (1) CY1125298T1 (https=)
DK (1) DK3749668T3 (https=)
EA (1) EA202091834A1 (https=)
ES (1) ES2916406T3 (https=)
GE (2) GEAP202215429A (https=)
HR (1) HRP20220733T1 (https=)
HU (1) HUE058990T2 (https=)
IL (1) IL276483B2 (https=)
LT (1) LT3749668T (https=)
MD (1) MD3749668T2 (https=)
MX (1) MX394182B (https=)
PL (1) PL3749668T3 (https=)
PT (1) PT3749668T (https=)
RS (1) RS63323B1 (https=)
SG (1) SG11202006948XA (https=)
SI (1) SI3749668T1 (https=)
SM (1) SMT202200277T1 (https=)
UA (1) UA126870C2 (https=)
WO (1) WO2019154770A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116253696A (zh) * 2021-12-10 2023-06-13 安徽省化工研究院 一种噁草酮的连续流制备方法
CN114891019B (zh) * 2022-02-25 2024-06-04 复旦大学 一种乙烯基硫醚化合物的连续流制备方法
CN117358178A (zh) * 2023-12-08 2024-01-09 天津凯莱英医药科技发展有限公司 丙硫菌唑的连续化合成系统及方法
CN118162064B (zh) * 2024-05-15 2024-08-30 济南大学 一种美罗培南母核中间体的连续化生产装置及方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
US4252806A (en) * 1979-09-24 1981-02-24 Mead Johnson & Company Triazoloquinolones
US4254124A (en) 1979-09-24 1981-03-03 Mead Johnson & Company Antidepressant agent
HU201324B (en) 1988-07-29 1990-10-28 Egyt Gyogyszervegyeszeti Gyar New process for production of substituated 1,2,4-triasole (4,3-a)-piridin-2 (2h)-on
AU663057B2 (en) 1990-09-28 1995-09-28 Pharmacia & Upjohn Company Anthelmintic and anticoccidal 3-carbamoyl-4-hydroxycoumarins
CA2182241C (en) 1996-07-29 2002-09-17 Bo Lei Methods for the manufacture of nefazodone
IT1314283B1 (it) 1999-12-16 2002-12-06 Acraf Trazodone cloridrato ed un procedimento per prepararlo.
ITMI20071603A1 (it) 2007-08-03 2009-02-04 Acraf Trazodone e trazodone cloridrato in forma purificata
WO2017166050A1 (zh) * 2016-03-29 2017-10-05 深圳市泛谷药业股份有限公司 一种盐酸曲唑酮的制备方法
CN105777745A (zh) 2016-03-29 2016-07-20 深圳市泛谷药业股份有限公司 一种盐酸曲唑酮的制备方法

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