JP2021511344A5 - - Google Patents

Info

Publication number
JP2021511344A5
JP2021511344A5 JP2020540459A JP2020540459A JP2021511344A5 JP 2021511344 A5 JP2021511344 A5 JP 2021511344A5 JP 2020540459 A JP2020540459 A JP 2020540459A JP 2020540459 A JP2020540459 A JP 2020540459A JP 2021511344 A5 JP2021511344 A5 JP 2021511344A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
day
composition according
compound
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020540459A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021511344A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/014489 external-priority patent/WO2019144098A1/en
Publication of JP2021511344A publication Critical patent/JP2021511344A/ja
Publication of JP2021511344A5 publication Critical patent/JP2021511344A5/ja
Pending legal-status Critical Current

Links

JP2020540459A 2018-01-22 2019-01-22 癌を治療する組成物および方法 Pending JP2021511344A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862620209P 2018-01-22 2018-01-22
US62/620,209 2018-01-22
PCT/US2019/014489 WO2019144098A1 (en) 2018-01-22 2019-01-22 Compositions and methods of treating cancer

Publications (2)

Publication Number Publication Date
JP2021511344A JP2021511344A (ja) 2021-05-06
JP2021511344A5 true JP2021511344A5 (enExample) 2022-02-24

Family

ID=65279826

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020540459A Pending JP2021511344A (ja) 2018-01-22 2019-01-22 癌を治療する組成物および方法

Country Status (13)

Country Link
US (2) US20190224205A1 (enExample)
EP (1) EP3743076A1 (enExample)
JP (1) JP2021511344A (enExample)
KR (1) KR20200112904A (enExample)
CN (1) CN111629731A (enExample)
AU (1) AU2019209435A1 (enExample)
BR (1) BR112020014574A2 (enExample)
CA (1) CA3088542A1 (enExample)
EA (1) EA202091751A1 (enExample)
IL (1) IL276203A (enExample)
MX (1) MX2020007526A (enExample)
SG (1) SG11202006823XA (enExample)
WO (1) WO2019144098A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2726206C2 (ru) 2015-05-21 2020-07-09 Кемосентрикс, Инк. Модуляторы ccr2
EP3687525B1 (en) 2017-09-25 2025-10-29 ChemoCentryx, Inc. Combination therapy using a chemokine receptor 2 (ccr2) antagonist and a pd-1/pd-l1 inhibitor
US20190269664A1 (en) 2018-01-08 2019-09-05 Chemocentryx, Inc. Methods of treating solid tumors with ccr2 antagonists
WO2022032187A1 (en) 2020-08-07 2022-02-10 Bristol-Myers Squibb Company Fgf21 combined with ccr2/5 antagonists for the treatment of fibrosis

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2706547T3 (es) 1998-12-23 2019-03-29 Pfizer Anticuerpos monoclonales humanos para CTLA-4
ES2539411T3 (es) 1999-08-23 2015-06-30 Dana-Farber Cancer Institute, Inc. PD-1, receptor para la B7-4 y su utilización
NZ517202A (en) 1999-08-24 2004-05-28 Medarex Inc Human CTLA-4 antibodies and their uses
ES2367430T3 (es) 2002-12-23 2011-11-03 Wyeth Llc Anticuerpos contra pd-1 y sus usos.
US7163937B2 (en) 2003-08-21 2007-01-16 Bristol-Myers Squibb Company Cyclic derivatives as modulators of chemokine receptor activity
EP3530736A3 (en) 2005-05-09 2019-11-06 ONO Pharmaceutical Co., Ltd. Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics
KR101704734B1 (ko) 2005-07-01 2017-02-09 이. 알. 스퀴부 앤드 선즈, 엘.엘.씨. 예정 사멸 리간드 1 (피디-엘1)에 대한 인간 모노클로날 항체
WO2007113648A2 (en) 2006-04-05 2007-10-11 Pfizer Products Inc. Ctla4 antibody combination therapy
PT2170959E (pt) 2007-06-18 2014-01-07 Merck Sharp & Dohme Anticorpos para o receptor humano de morte programada pd-1
US8168757B2 (en) 2008-03-12 2012-05-01 Merck Sharp & Dohme Corp. PD-1 binding proteins
MX356367B (es) 2008-12-09 2018-05-25 Genentech Inc Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t.
CN102484041B (zh) * 2009-08-21 2015-09-23 第一太阳能有限公司 高温计
US8383812B2 (en) * 2009-10-13 2013-02-26 Bristol-Myers Squibb Company N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-A][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide, a dual modulator of chemokine receptor activity, crystalline forms and processes
EP3279215B1 (en) 2009-11-24 2020-02-12 MedImmune Limited Targeted binding agents against b7-h1
ES2699965T3 (es) 2011-03-10 2019-02-13 Provectus Pharmatech Inc Una combinación de rosa de bengala y anticuerpo anti-CTLA4 para su uso en el tratamiento del cáncer
CA2833636A1 (en) 2011-04-20 2012-10-26 Amplimmune, Inc. Antibodies and other molecules that bind b7-h1 and pd-1
BR112014012819B1 (pt) 2011-11-28 2022-08-16 Merck Patent Gmbh Anticorpo anti-pd-l1 ou fragmento de ligação ao antígeno do mesmo e composição
US9856320B2 (en) 2012-05-15 2018-01-02 Bristol-Myers Squibb Company Cancer immunotherapy by disrupting PD-1/PD-L1 signaling
US9175082B2 (en) 2012-05-31 2015-11-03 Sorrento Therapeutics, Inc. Antigen binding proteins that bind PD-L1
RS61400B1 (sr) 2013-05-02 2021-02-26 Anaptysbio Inc Antitela usmerena protiv programirane smrti-1 (pd-1)
CA3175360C (en) 2013-05-31 2024-05-28 Sorrento Therapeutics, Inc. Antigen binding proteins that bind pd-1
CN104250302B (zh) 2013-06-26 2017-11-14 上海君实生物医药科技股份有限公司 抗pd‑1抗体及其应用
SMT202300039T1 (it) 2013-09-13 2023-03-17 Beigene Switzerland Gmbh Anticorpi anti-pd1 e loro uso come terapia e per diagnostica
CR20160319A (es) 2013-12-12 2016-11-08 Jiangsu Hengrui Medicine Co Anticuerpo pd-1, fragmento de union al antigeno de este y uso médico de este
TWI681969B (zh) 2014-01-23 2020-01-11 美商再生元醫藥公司 針對pd-1的人類抗體
UA122479C2 (uk) 2014-01-24 2020-11-25 Дана-Фарбер Кенсер Інстітьют, Інк. Виділена молекула антитіла, яка зв’язується з людським білком програмованої смерті-1 (pd-1)
CA2971734C (en) 2014-12-22 2025-11-18 Pd-1 Acquisition Group, Llc Anti-pd-1 antibodies
MA42971A (fr) 2015-03-13 2018-08-15 Cytomx Therapeutics Inc Anticorps anti-pdl1, anticorps anti-pld1 activables, et leurs procédés d'utilisation
DK3303394T3 (da) 2015-05-29 2020-07-06 Agenus Inc Anti-ctla-4-antistoffer og fremgangsmåder til anvendelse deraf
WO2016197367A1 (en) 2015-06-11 2016-12-15 Wuxi Biologics (Shanghai) Co. Ltd. Novel anti-pd-l1 antibodies
RU2766890C2 (ru) * 2015-06-16 2022-03-16 Мерк Патент Гмбх Комбинированные способы лечения антагонистами pd-l1
WO2017020291A1 (en) 2015-08-06 2017-02-09 Wuxi Biologics (Shanghai) Co. Ltd. Novel anti-pd-l1 antibodies
WO2017024465A1 (en) 2015-08-10 2017-02-16 Innovent Biologics (Suzhou) Co., Ltd. Pd-1 antibodies
WO2017024515A1 (en) 2015-08-11 2017-02-16 Wuxi Biologics (Cayman) Inc. Novel anti-pd-1 antibodies
MX392711B (es) 2015-08-11 2025-03-24 Wuxi Biologics Ireland Ltd Anticuerpos anti-pd-1 novedosos.
AR105654A1 (es) 2015-08-24 2017-10-25 Lilly Co Eli Anticuerpos pd-l1 (ligando 1 de muerte celular programada)
JP6869987B2 (ja) 2015-09-01 2021-05-12 アジェナス インコーポレイテッド 抗pd−1抗体及びその使用方法
CN108367069B (zh) 2015-12-14 2022-08-23 宏观基因有限公司 对于pd-1和ctla-4具有免疫反应性的双特异性分子及其使用方法
EP3389581A2 (en) * 2015-12-15 2018-10-24 The Procter and Gamble Company Leg gasketing cuff with tackifier-free adhesive
JP7082051B2 (ja) 2016-01-11 2022-06-07 アルモ・バイオサイエンシーズ・インコーポレイテッド 抗原特異的cd8+t細胞の産生におけるインターロイキン-10及びその使用方法
WO2017132827A1 (en) 2016-02-02 2017-08-10 Innovent Biologics (Suzhou) Co., Ltd. Pd-1 antibodies
EP3402255B1 (en) 2016-02-02 2021-03-31 Huawei Technologies Co., Ltd. Emission power verification method, user equipment, and base station
WO2017165125A1 (en) * 2016-03-24 2017-09-28 Millennium Pharmaceuticals, Inc. Use of a pd-1 antagonist and an anti-ccr2 antibody in the treatment of cancer
SMT202200088T1 (it) * 2017-07-20 2022-03-21 Bristol Myers Squibb Co Procedimento per la preparazione di n-((1r,2s,sr)-5-(tert-butilammino)-2-((s)-3-(7-tert-butilpirazolo[1,5-a][1,3,5]triazin-4-ilammino)-2-ossopirrolidin-1-il)cicloesil)acetammide

Similar Documents

Publication Publication Date Title
JP2020514311A5 (enExample)
JP2020519295A5 (enExample)
JP2021059564A (ja) 癌治療のための併用療法
TW201922793A (zh) Pd-1抗體和vegfr抑制劑聯合治療小細胞肺癌的用途
JP2019517549A5 (enExample)
JP2022511394A5 (enExample)
JP2016520082A5 (enExample)
JP2016530323A5 (enExample)
RU2018146886A (ru) Пути терапевтического применения ингибитора c-raf
JP2021520406A5 (enExample)
JP6425653B2 (ja) 抗腫瘍剤及び抗腫瘍効果増強剤
RU2018103064A (ru) Комбинация ингибитора hdac и анти-pd-l1-антитела для лечения злокачественной опухоли
JP2022512826A5 (enExample)
JP2022512851A5 (enExample)
JP2019506392A5 (enExample)
JP2018512402A5 (enExample)
JP2022527334A5 (enExample)
JPWO2022270524A5 (enExample)
JP2024016209A5 (enExample)
JP2022523045A5 (enExample)
Cheng et al. Antibody-mediated blockade of phosphatidylserine enhances the antitumor effect of sorafenib in hepatocellular carcinomas xenografts
JP2022501332A5 (enExample)
TW202128224A (zh) 抗pd-1抗體和組蛋白去乙醯化酶抑制劑的藥物組合及其用途、使用方法
JP2020536068A5 (enExample)
CA2483826A1 (en) Epothilone derivative for the treatment of hepatoma and other cancer diseases